1.Diurnal variation, moon phase and seasonal variation in onset of stroke
Chinese Journal of Rehabilitation Theory and Practice 2003;9(5):284-285
ObjectiveTo determine the diurnal variation,moon phase,and seasonal variation in the onset of stroke. MethodsThe time parameters,including the time,the moon phase and the season of the stroke occurrence for 905 in-patients from 1989-2001 were investigated.ResultsThere was a significant difference (D=0.155,P<0.01) for circadian rhythm in the onset of 321 cases with cerebral infarction,and the incidence frequency at dawn was much higher than that at other time,but the difference of the moon phase and seasonal rhythm in the onset of cerebral infarction were not significant(P>0.05).There were not diurnal variation,moon phase and seasonal rhythms in the onset for cerebral haemorrhage(P>0.05).ConclusionsThe cerebral infarction occur more frequently at dawn time.
2.Correlative factor analysis of loss of functional status in healthy elderly people
Chinese Journal of Tissue Engineering Research 2005;9(47):144-146
BACKGROUND: Health status of elderly people is an important problem concerned by the whole society. To find the way of preventing loss of functional status of daily life for elderly people is the key to generally improving the quality of life in elderly people.OBJECTIVE: To observe the main characteristics of function loss in healthy elderly people and analyze the influencing factors of the change of functional indexes in elderly people in normal functional status.DESIGN: Contrast observation; Logistic analysis.SETTING: Student's Office, Shangrao Normal College.PARTICIPANTS: All the data were from the sampling questionnaire survey on health status of 1 700 people including retired cadres and employees from 11 cities of Jiangxi province. The survey was conducted by Senile Physical Education Association of Jiangxi Province in January 2004.METHODS: The test was performed depending on 4 indexes in physical self-maintenance scale including dressing, taking food, bathing and toileting along with other indexes of shopping, calling, riding, going upstairs to the third floor, walking for 1 000 m, taking things by fingers and squatting & standing. These 11 indexes were used for evaluating the functional status of daily life in elderly people. According to international definition,people with difficulty in one or more indexes could be defined as ability loss of self-cave in daily life. The participants were demanded to give the score of difficulty in independently completing each activity including not difficult (1), somewhat difficult (2), very difficult (3), completely impossible (4). The total sum of 11 scores was defined as functional status index of daily life. Its value reflected the whole situation of functional status of daily life in elderly people. The higher the index was, the worse the functional status was. Comparison was conducted among groups of different gender and age, and Logistic regression analysis was used for evaluationand analysis.MAIN OUTCOME MEASURES: Evaluation of functional index, function loss rate of daily life, index in independent physical self-maintenance ability of daily life.RESULTS: ① Normal functional status of elderly people is various due to the different age, gender, constitution, marital status, living situation,employment history, economic status and education background etc. ② As far as function loss rate of daily life in healthy elderly people was concerned, male was higher than female, and people taking part-time jobs and rehired after retirement were higher than other retirees. When it came to loss rate of motor function of lower limbs, widowed people were higher than not widowed, and the higher the education, the better motor functional status of lower limbs the male had, while the situation was reversed for female.CONCLUSION: Loss rate of normal functional status of elderly people significantly decreases as their age increases, and it is relevant to the complexity and difficulty of activities of life. Normal functional status of elderly people is related to social support, economic status, psychological and mental status.
3.Investigation and analysis of nursing undergraduate's graduation thesis writing
Chinese Journal of Medical Education Research 2012;11(3):278-280
ObjectiveTo understand the nursing undergraduates' graduation thesis writing,to provide basis for the revised management plan and improve the overall quality of graduation thesis.Methods A self-designed questionnaire was given to 158 four-year program nursing graduates of Grade 2006 by group and the questionnaires were collected timely and analyzed with SPSS 17.0.Results63.19% of students thought it necessary to write thesis,86.71% thought internship beneficial for wrting and 64.6% hoped to finish the thesis writing before the practice because of great pressure.ConclusionStudents' recognition degree to graduation thesis directly affects the quality of thesis writing.A reasonable teaching plan should be made and school resources should be fully used to improve the quality of thesis writing.
4.Effect of optimized disposition of surgical instrument packages on nurses’efficiency
Modern Clinical Nursing 2013;(2):66-69
Objective To study the effect of optimized disposition of surgical instrument packages on nurses’efficiency. Methods 200 cases of surgeries were randomized equally into an experiment group and a control group: the former used optimized disposition of surgical instrument packages and the control group convention surgical instruments package.The two groups were compared in terms of time for counting the instruments and recirculation treatment of postoperative apparatus as well as the effect of the packages on the operation space for nurses.Results The time for counting the instruments and recirculation treatment of postoperative apparatus in the experiment group was significantly shorter than those in the control group(both P<0.01).The weight,volume and space of the packages in the experiment group were significantly smaller than those in the control group(all P<0.01).Conclusion The optimized disposition of surgical instrument package may shorten the nursing operation time,reduce consumption of energy, improve the operational settings and increase the working efficiency.
5.Transpedicular vertebral body bone graft combined with pedicle screw fixation in the treatment of thoracic and lumbar fractures
Chinese Journal of Primary Medicine and Pharmacy 2012;19(14):2122-2123
Objective To investigate the effect of the transpedical interbody bone grafting plus pedicle screw fixation for the treatment of thoracic and lumbar fractures.Methods 67 thoracolumbar fracture patients were treated with transpedicular vertebral body bone graft and pedicle screw internal fixation operation,preoperative,postoperative and follow-up uptake X line inspection,measurement and observation of.vertebral height has no loss,no fracture,internal fixation loosening occurred.Results Patients with neurological injury after operation were improved to different degree,the follow-up of patients with 12 ~ 36(23.8±9.3) average.After 1 year the patient fixation was not removed,internal fixation loosening,fracture,bone graft fusion better,no bone resorption and spinal physiological curvature to maintain good.Postoperative patients,followed for a mean of 36 months of anterior vertebral body height,height of vertebral body,posterior margin of the vertebral body height and the central angle Cobb operation were decreased significantly,the difference was statistically significant(P < 0.05);and 1 week after operation and postoperative follow-up of an average of 36 months each index showed no significant differenec(P >0.05).Conclusion Transpedicular vertebral body bone graft and pedicle screw fixation for the treatment of thoracolumbar fractures has good clinical curative effect,which could effectively maintain the vertebral height of the front,with the value of clinical application.
6.The value of the combine detection of blood lipid,blood glucose,liver function and serum uric acid in the diagnosis of elderly patients with fatty liver
International Journal of Laboratory Medicine 2017;38(15):2040-2042,2045
Objective To explore the application value of blood lipid,blood glucose,liver function and serum uric acid in the diagnosis of fatty liver in elderly patients.Methods A total of 62 elderly patients with fatty liver in our hospital from April 2016 to October 2016 were selected as study group,and 62 healthy persons were selected as control group.All the subjects were drawn fasting venous blood 4 mL.Rate method was used to detected liver function indexes of total bile acid(TBA),gamma glutamyltranspeptidase(GGT) and aspartate aminotransferase(AST),alanine aminotransferase(ALT),total bilirubin(TBIL) levels.The hexokinase method was used to detected blood lipid indexes,including very low density lipoprotein cholesterol(VLDL-C),low density lipoprotein cholesterol(LDL-C),high density lipoprotein cholesterol(HDL-C),cholesterol(TC),triglyceride(TG) levels.The peroxidase colorimetric method was used to detected blood glucose index including glycated hemoglobin(HbA1c) and fasting blood glucose(FBG) levels.MINDRAY BS-400 automatic biochemical analyzer produced in Shenzhen MINDRAY company was used to detect the serum uric acid level.Value of blood lipid,blood glucose,liver function,serum uric acid in diagnosis for fatty liver were made statistical comparison.Results The levels of TBA,GGT,AST,ALT and TBIL in the study group were higher than those in the control group,the level of VLDL-C,LDL-C,TG,TC in the study group were higher than those in the control group,the HDL-C level was lower than that in the control group,the levels of FBG and HbA1c in the study group were higher than those in the control group,the level of serum uric acid in the study group[(447.12±91.03)μmol/L] was higher than that in the control group [(353.41±70.32)μmol/L],the differences were all had statistically significant(P<0.05).The sensitivity(80.65%,79.03%,82.26%,77.42%) and accuracy(90.32%,88.71%,90.32%,88.71%) of blood lipids,blood glucose,liver function,blood uric acid alone in diagnosis of fatty liver were lower than the combined diagnosis(95.16%,96.77%),the differences were statistically significant(P<0.05).Conclusion Fatty liver patients have abnormal blood lipids and blood glucose,liver function and blood uric acid level,combined with the above indexes for diagnosis can improve the sensitivity and accuracy of fatty liver,and provide guidance for the intervention,is worthy of promotion.
7.Analysis of Drug Use in 119 Cases of Acute Myocardial Infarction
China Pharmacy 1991;0(06):-
OBJECTIVE: To investigate the use of ?-receptor blockers,angiotensin converting enzyme inhibitors,aspirin and statins in acute myocardial infarction patients. METHODS: The general information of 119 cases of established acute myocardial infarction in 4 hospitals in Jiangbei district of Chongqing between 1999 to 2004 were analyzed retrospectively. RESULTS: The suitable use rates of ?-receptor blocker and angiotensin converting enzyme inhibitor are 79.0% and 85.7%, respectively, while their actual rates were 35.3% and 43.7%,respectively. Therefore among the suitable patients,55.3% of them did not receive the treatment with ?-receptor blockers and 49.0% did not take angiotensin converting enzyme inhibitors properly. The use rate of aspirin was high to 84.9%. The statins was not used until 2002 and its use rate was 15.1%. CONCLUSION: There exists significant gap between the practice and the requirement in“diagnositic and therapeutic guide for acute myocardial infarction” in the use of these drugs, except the aspirin. However, this situation is being changed.
8.Pharmacodynamic Study on the Antiinflammatory and Analgesic Effects of Jingangteng Dispersible Tablets
China Pharmacy 2007;0(36):-
OBJECTIVE:To study the antiinflammatory and analgesic effect of Jingangteng dispersible tablet (JDT). METHODS:The antiinflammatory effect of JDT was studied on pinna swelling model mice, the voix pedis swelling model rats and the cotton ball granuloma model rats; the writhing experiment in mice was done to study the analgesic effect of JDT, with Jingangteng capsule(JC) as a positive control. RESULTS:JDT significantly inhibited mice's swelling of pinna induced by xylene, rats' swelling of the voix pedis induced by albumen, rats' granulomatous accrementition induced by cotton ball as well as mice's writhing response induced by acetic acid, with effects superior to those of JC(P
9.Omeprazole-induced ADR:Literature Analysis of 96 Cases
China Pharmacy 2001;0(11):-
OBJECTIVE: To study the condition and the related factors of adverse drug reactions (ADR) occurred in our hospital. METHODS: A total of 75 omeprazole-induced ADR reports (96 cases) retrieved from 1996 to Mar. 2007 published in domestic medical journals were analyzed statistically. RESULTS: Omeprazole-induced ADR were mostly seen in males aged from 41 to 60, but which was independent of sex. The ADR induced by oral administration usually appeared within 3 days to 2 weeks, while those induced by injection were more often seen at 3~5 min or 3 days later. The ADR might involve multi-organs or systems, and their clinical manifestations were various and complicated, chiefly characterized by allergic reactions and hypolekocytosis, or even allergic shock in severe cases. CONCLUSION: ADR induced by omeprazole call for great attention in the clinic.
10.Application of syngo RESOLVE MRI diffusion weighted imaging in the diagnosis of ovarian neoplasms
Chinese Journal of Primary Medicine and Pharmacy 2016;23(13):1936-1938,1939
Objective To compare the value of syngo RESOLVE DWI and conventional full field-of-view (f -FOV)DWI in the diagnosis of ovarian tumors with 3.0T MRI scanner.Methods 21 consecutive patients with ovarian tumors confirmed by operation and pathology were selected.All patients underwent routine MRI plain scanning,RESOLVE DWI and f -FOV DWI with a 3.0T MRI scanner.ADC values measured the RESOLVE and the traditional DWI images of ovarian tumors,used the method of four points by two imaging diagnostic doctors to image the display effect of ovarian tumor in subjective ratings.SPSS 13.0 software was used for statistical analysis.Results The subjective score of tumors ovarian showing of RESOLVE DWI was (3.62 ±0.44)points,which of f -FOV DWI was (2.93 ±0.51)points,there was statistically significant difference(Z =-3.787,P <0.05);The average ADC value of ovarian tumor in RESOLVE DWI was (0.824 ±0.157)×10 -3 mm2 /s,that in f -FOV DWI was (0.775 ± 0.147)×10 -3 mm2 /s,there was no statistically significant difference(t =1.038,P >0.05).Conclusion In ovarian tumor MRI DWI examination,compared with f -FOV DWI,RESOLVE DWI can obtain higher space resolution,higher image quality,and obtain accurate quantitative parameter values.