Objective To sort out the organisational support strategies adopted by typical public hospitals to improve the mental health of healthcare workers,to provide reference for hospitals around the world,and to enhance the healthcare health force.Methods In December 2023,57 cases of organisational support for healthcare workers'mental health in public hospitals were searched and screened,and the textual content of specific measures in the case hospitals was coded using thematic framework analysis.Two rounds of expert consultation were conducted to further screen typical cases.Results 4 General strategies of system optimisation,professional services,promotion and education,and humanistic care and their corresponding 9 sub-strategies were identified based on the coding content.The 11 typical cases screened by experts were further summarised and analysed to distil the specific practices carried out by each hospital to improve the mental health of healthcare workers.Conclusion The mental health status of healthcare workers is not optimistic,and hospitals need to pay full attention to it and take supportive organisational measures to address the existing problems.For example,expanding the reserve of psychological professionals,enhancing the application of information technology,and improving the willingness of healthcare professionals to accept mental services.

Objective To sort out the organisational support strategies adopted by typical public hospitals to improve the mental health of healthcare workers,to provide reference for hospitals around the world,and to enhance the healthcare health force.Methods In December 2023,57 cases of organisational support for healthcare workers'mental health in public hospitals were searched and screened,and the textual content of specific measures in the case hospitals was coded using thematic framework analysis.Two rounds of expert consultation were conducted to further screen typical cases.Results 4 General strategies of system optimisation,professional services,promotion and education,and humanistic care and their corresponding 9 sub-strategies were identified based on the coding content.The 11 typical cases screened by experts were further summarised and analysed to distil the specific practices carried out by each hospital to improve the mental health of healthcare workers.Conclusion The mental health status of healthcare workers is not optimistic,and hospitals need to pay full attention to it and take supportive organisational measures to address the existing problems.For example,expanding the reserve of psychological professionals,enhancing the application of information technology,and improving the willingness of healthcare professionals to accept mental services.

Objective To sort out the organisational support strategies adopted by typical public hospitals to improve the mental health of healthcare workers,to provide reference for hospitals around the world,and to enhance the healthcare health force.Methods In December 2023,57 cases of organisational support for healthcare workers'mental health in public hospitals were searched and screened,and the textual content of specific measures in the case hospitals was coded using thematic framework analysis.Two rounds of expert consultation were conducted to further screen typical cases.Results 4 General strategies of system optimisation,professional services,promotion and education,and humanistic care and their corresponding 9 sub-strategies were identified based on the coding content.The 11 typical cases screened by experts were further summarised and analysed to distil the specific practices carried out by each hospital to improve the mental health of healthcare workers.Conclusion The mental health status of healthcare workers is not optimistic,and hospitals need to pay full attention to it and take supportive organisational measures to address the existing problems.For example,expanding the reserve of psychological professionals,enhancing the application of information technology,and improving the willingness of healthcare professionals to accept mental services.

Objective To sort out the organisational support strategies adopted by typical public hospitals to improve the mental health of healthcare workers,to provide reference for hospitals around the world,and to enhance the healthcare health force.Methods In December 2023,57 cases of organisational support for healthcare workers'mental health in public hospitals were searched and screened,and the textual content of specific measures in the case hospitals was coded using thematic framework analysis.Two rounds of expert consultation were conducted to further screen typical cases.Results 4 General strategies of system optimisation,professional services,promotion and education,and humanistic care and their corresponding 9 sub-strategies were identified based on the coding content.The 11 typical cases screened by experts were further summarised and analysed to distil the specific practices carried out by each hospital to improve the mental health of healthcare workers.Conclusion The mental health status of healthcare workers is not optimistic,and hospitals need to pay full attention to it and take supportive organisational measures to address the existing problems.For example,expanding the reserve of psychological professionals,enhancing the application of information technology,and improving the willingness of healthcare professionals to accept mental services.

Objective To sort out the organisational support strategies adopted by typical public hospitals to improve the mental health of healthcare workers,to provide reference for hospitals around the world,and to enhance the healthcare health force.Methods In December 2023,57 cases of organisational support for healthcare workers'mental health in public hospitals were searched and screened,and the textual content of specific measures in the case hospitals was coded using thematic framework analysis.Two rounds of expert consultation were conducted to further screen typical cases.Results 4 General strategies of system optimisation,professional services,promotion and education,and humanistic care and their corresponding 9 sub-strategies were identified based on the coding content.The 11 typical cases screened by experts were further summarised and analysed to distil the specific practices carried out by each hospital to improve the mental health of healthcare workers.Conclusion The mental health status of healthcare workers is not optimistic,and hospitals need to pay full attention to it and take supportive organisational measures to address the existing problems.For example,expanding the reserve of psychological professionals,enhancing the application of information technology,and improving the willingness of healthcare professionals to accept mental services.

Objective To sort out the organisational support strategies adopted by typical public hospitals to improve the mental health of healthcare workers,to provide reference for hospitals around the world,and to enhance the healthcare health force.Methods In December 2023,57 cases of organisational support for healthcare workers'mental health in public hospitals were searched and screened,and the textual content of specific measures in the case hospitals was coded using thematic framework analysis.Two rounds of expert consultation were conducted to further screen typical cases.Results 4 General strategies of system optimisation,professional services,promotion and education,and humanistic care and their corresponding 9 sub-strategies were identified based on the coding content.The 11 typical cases screened by experts were further summarised and analysed to distil the specific practices carried out by each hospital to improve the mental health of healthcare workers.Conclusion The mental health status of healthcare workers is not optimistic,and hospitals need to pay full attention to it and take supportive organisational measures to address the existing problems.For example,expanding the reserve of psychological professionals,enhancing the application of information technology,and improving the willingness of healthcare professionals to accept mental services.

Objective To sort out the organisational support strategies adopted by typical public hospitals to improve the mental health of healthcare workers,to provide reference for hospitals around the world,and to enhance the healthcare health force.Methods In December 2023,57 cases of organisational support for healthcare workers'mental health in public hospitals were searched and screened,and the textual content of specific measures in the case hospitals was coded using thematic framework analysis.Two rounds of expert consultation were conducted to further screen typical cases.Results 4 General strategies of system optimisation,professional services,promotion and education,and humanistic care and their corresponding 9 sub-strategies were identified based on the coding content.The 11 typical cases screened by experts were further summarised and analysed to distil the specific practices carried out by each hospital to improve the mental health of healthcare workers.Conclusion The mental health status of healthcare workers is not optimistic,and hospitals need to pay full attention to it and take supportive organisational measures to address the existing problems.For example,expanding the reserve of psychological professionals,enhancing the application of information technology,and improving the willingness of healthcare professionals to accept mental services.

Objective To sort out the organisational support strategies adopted by typical public hospitals to improve the mental health of healthcare workers,to provide reference for hospitals around the world,and to enhance the healthcare health force.Methods In December 2023,57 cases of organisational support for healthcare workers'mental health in public hospitals were searched and screened,and the textual content of specific measures in the case hospitals was coded using thematic framework analysis.Two rounds of expert consultation were conducted to further screen typical cases.Results 4 General strategies of system optimisation,professional services,promotion and education,and humanistic care and their corresponding 9 sub-strategies were identified based on the coding content.The 11 typical cases screened by experts were further summarised and analysed to distil the specific practices carried out by each hospital to improve the mental health of healthcare workers.Conclusion The mental health status of healthcare workers is not optimistic,and hospitals need to pay full attention to it and take supportive organisational measures to address the existing problems.For example,expanding the reserve of psychological professionals,enhancing the application of information technology,and improving the willingness of healthcare professionals to accept mental services.

Objective:To investigate the infection rate in close contacts of COVID-19 patients before and after the last negative nucleic acid test, evaluate the effect of dynamic nucleic acid test in determining the infectivity of COVID-19 patients.Methods:Dynamic nucleic acid test results of COVID-19 cases were collected in a retrospective cohort study. COVID-19 cases with negative nucleic acid test results before their first positive nucleic acid tests were selected as study subjects. Close contacts of the index cases and the secondary close contacts were kept isolation for medical observation to assess their risk of infection.Results:This study included 89 confirmed cases from two local COVID-19 epidemics in Ningbo. A total of 5 609 close contacts were surveyed, the overall infection rate was 0.20%. No close contacts of the COVID-19 cases before the last negative nucleic acid test were infected, and the infection rate in the close contacts of the COVID-19 cases after the last negative nucleic acid test was 1.33%, all of these close contacts lived together with the index cases. No secondary close contacts were infected.Conclusion:COVID-19 patient becomes infectious after the last nucleic acid is negative, and has no infectivity before the last nucleic acid negative.

Objective:To evaluate the early diagnostic value of tissue inhibitor of matrix metalloproteinase-2 (TIMP-2) and insulin-like growth factor binding protein-7 (IGFBP-7) in acute kidney injury induced by sepsis.Methods:A total of 85 sepsis patients admitted to the EICU and GICU in Shanghai East Hospital from September 2017 to June 2019 were divided into theAKI group ( n=37) and the non-AKI group ( n=48) according to KIDGO diagnostic criteria, and 20 healthy volunteers were served as the control group. The clinical data were recorded and samples of urine were collected at 0 h, 6 h, 12 h, 1 d, 3 d and 7 d post sepsis. The levels of TIMP-2 and IGFBP-7 in the urine were analyzed with ELISA at different time points. Based on the receiver operating characteristic curve (ROC) and the area under the curve (AUC), the early diagnostic value of urinary TIMP-2 and IGFBP-7 in sepsis-induced AKI patients was determined. Results:Compared with the control group, the levels of TIMP-2 and IGFBP-7 of the AKI group were significantly higher at the above time points ( P<0.05), while those of the non-AKI group showed no significant differences. The levels of TIMP-2 and IGFBP-7 of the AKI group were significantly higher than the those of the non-AKI group ( P<0.05). ROC analysis showed that when the AUC of urine TIMP-2 peaked at 1 d, the sensitivity and specificity reached 97.5% and 81.2%, separately with the cutoff value of 151.23 ng/mL. Furthermore, when the AUC of urine IGFBP-7 peaked at 12 h, the sensitivity and specificity reached 100% and 72.8%, separately with the cutoff value of 14.91 ng/mL. Interestingly, when the AUC of combined TIMP-2×IGFBP-7 peaked at 12 h, the sensitivity reached 98.0% and specificity reached 91.5% with the cutoff value of 2.09 [(ng/mL) 2/1 000]. There was no significant correlation between the levels of TIMP-2 and IGFBP-7 with SOFA and APACHEⅡ score at 1 d, 3 d and 7 d post sepsis in the AKI group ( P>0.05). Conclusions:Urine TIMP-2 and IGFBP-7 have early diagnostic value in sepsis-induced AKI. Besides, the combination of the two biomarkers have superior predictive value than each single of them.