1.Inheritance on and innovation of traditional Chinese medicine (TCM) flavor theory and TCM flavor standardization principle flavor theory in Compendium of Materia Medica.
Wei ZHANG ; Rui-xian ZHANG ; Jian LI
China Journal of Chinese Materia Medica 2015;40(24):4928-4931
All previous literatures about Chinese herbal medicines show distinctive traditional Chinese medicine (TCM) flavors. Compendium of Materia Medica is an influential book in TCM history. The TCM flavor theory and flavor standardization principle in this book has important significance for modern TCM flavor standardization. Compendium of Materia Medica pays attention to the flavor theory, explain the relations between the flavor of medicine and its therapeutic effects by means of Neo-Confucianism of the Song and Ming Dynasties. However,the book has not reflected and further developed the systemic theory, which originated in the Jin and Yuan dynasty. In Compendium of Materia Medica , flavor are standardized just by tasting medicines, instead of deducing flavors. Therefore, medicine tasting should be adopted as the major method to standardize the flavor of medicine.
Materia Medica
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standards
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Medicine, Chinese Traditional
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Reference Standards
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Taste
2.Herbalogical textual research of Wuyi.
Hai-liang ZHAO ; Rui-xian ZHANG
China Journal of Chinese Materia Medica 2015;40(22):4510-4513
Wuyi is one of the Chinese medicine recorded in Shennong's Herbal Classic and many other herbal books during the long history period. Up to now, Wuyi is still an important medicine used for insecticidal and removing food retention. Recent researches indicated that Wuyi also had the function of anti-malaria and treating herpetic simplex keratitis. Therefore, Wuyi had notable value on clinic and development of new medicine. The herbalogical textual research on Wuyi was conducted through investigation of the literature of materia medica during the long historical period from Han Dynasty. It was demonstrated by this work that the original plants of Wuyi include Ulmus macrocarpa Hance and Hemiptelea davidii (Hance) Planch, in which, U. macrocarpa was the quality specie. U. pumila was the false specie which cause confusing. The medicine Wuyi was the processed product made from the nutlet of the plants through fermentation with other additive agents.
China
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Drugs, Chinese Herbal
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analysis
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Herbals as Topic
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history
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History, Ancient
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Plants, Medicinal
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anatomy & histology
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chemistry
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classification
3.Achievement of Qimin Yaoshu in area of herbalogical textual research.
Hai-Liang ZHAO ; Rui-Xian ZHANG
China Journal of Chinese Materia Medica 2015;40(21):4306-4308
The achievement of Qimin Yaoshu in the area of herbalogical textual research was illustrated in this paper. Qimin Yaoshu quoted and keeped many contents from ancient agriculture books related in herbalogical literature. It also recorded the information of lots of tropical and subtropical plants. The author bringed forwarded many experiences indistinguishing plants and clarified some long last confused or wrong opinions. The studying philosophy and methods of the authors gave us much enlightenment in our herbalogical textual research. It should be taken into account when the herbalogical textual research was carried out.
China
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Drugs, Chinese Herbal
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chemistry
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pharmacology
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Herbals as Topic
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history
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History, Ancient
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Medicine in Literature
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Plants, Medicinal
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anatomy & histology
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chemistry
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classification
4.Achievement of Nongzheng Quanshu in area of herbalogical textual research.
Hai-liang ZHAO ; Rui-xian ZHANG
China Journal of Chinese Materia Medica 2015;40(23):4709-4710
The achievement of Nongzheng Quanshu in area of herhalogical textual research was illustrated in this paper. Nongzheng Quanshu recorded the information of 159 kinds of cultivated plants and 473 kinds of wild plants. It also quoted many contents from lots of ancient agriculture hooks related in herbalogical literature. Many agriculture researchers were encouraged to have done much work in area of herhalogical textual research It also included the materia medica hook Jiuhuang Bencao and Yecaipu therein and promoted their delivery.
Books
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history
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China
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History, Ancient
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Materia Medica
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history
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Medicine in Literature
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Plants, Medicinal
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chemistry
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classification
5.Study on suitable harvest time of Dendrobium officinale in Yunnan province.
Shan-bao ZHANG ; Ke-jun ZHOU ; Zhen ZHANG ; Rui-rui LU ; Xian LI ; Xiao-hua LI
China Journal of Chinese Materia Medica 2015;40(18):3549-3552
In order to determine the suitable harvest time of Dendrobium officinale from different regions in Yunnan province, the drying rate, mannose and glucose peak area ratio, extract, contents of polysaccharide and mannose of D. officinale samples collected from six producing areas in Ynnnan province were determined. The results indicate that drying rate and the contents of polysaccharide and mannose arrived the peak from January to April, extract reached a higher content from September to December, and mannose and glucose peak area ratio from October to February of the coming met the requirment of the Chinese Pharmacopoeia. Hence, the suitable harvesting time of D. officinale in Yunnan province is from December to February of the coming year,according to the experimental results and the request of the Chinese Pharmacopoeia.
China
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Dendrobium
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chemistry
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growth & development
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metabolism
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Glucose
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analysis
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metabolism
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Mannose
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analysis
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metabolism
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Time Factors
6.Clinical study for the artificial nerve canal to prevent irritating neuralgia after peripheral neurilemmoma resection
Rui ZHAO ; Yi JIANG ; Rui CONG ; Hang ZHANG ; Hang XIAN ; Chengwu ZANG
Chinese Journal of Microsurgery 2013;(2):133-136
Objective To investigate the preventive effect of the artificial nerve canal on irritating neuralgia after neurilemmoma resection.Methods Thirty patients diagnosed as neurilemmoma were divided into artificial nerve group and control group at randomly.There were 15 patients in each group.The nerves in artificial nerve group were enclosed using the artificial nerve besides neurilemmoma resection.The nerves in control group only had neurilemmoma resection.All patients were assessed with VAS for the degree of irritating neuralgia at 3 time points after operation.Calculate the incidence of irritating neuralgia and analyze the data using statistical methods.Results In control group,the VAS scores were 7.5,5.1,2.8,and the incidences of irritating neuralgia were 80%,67%,40%,respectively.In artificial nerve group,the VAS scores were 3.2,1.5,0,and the incidences of irritating neuralgia were 33%,13%,0.The VAS scores and the incidences of irritating neuralgia of two groups had significant difference by statistical analysis (P < 0.05).Conclusion The artificial nerve canal can relieve the degree and decrease the incidence of irritating neuralgia after neurilemmoma resection,which is a useful method to prevent irritating neuralgia in clinic.
7.Study on professor Yan Zhenghua's medication regularity in treating heart diseases based on association rules and entropy cluster.
Jia-rui WU ; Wei-xian GUO ; Xiao-meng ZHANG ; Bing ZHANG ; Yue ZHANG
China Journal of Chinese Materia Medica 2015;40(8):1601-1604
In this study, Professor Yan Zhenghua's recipes for treating heart diseases were collected to determine the frequency and association rules among drugs by such data mining methods as apriori algorithm and complex system entropy cluster and summarize Pro- fessor Yan Zhenghua's medication experience in treating heart diseases. The results indicated that frequently used drugs included Salviae Miltiorrhizae Radix et Rhizoma, Parched Ziziphi Spinosae Semen, Polygoni Multiflori Caulis, Ostreae Concha, Poria; frequently used drug combinations included "Ostreae Concha, Draconis Os", "Polygoni Multiflori Caulis, Parched Ziziphi Spinosae Semen" , and "Salviae Miltiorrhizae Radix et Rhizoma, Parched Ziziphi Spinosae Semen". The drug combinations with the confidence of 1 included "Dalbergiae Odoriferae Lignum-->Salviae Miltiorrhizae Radix et Rhizoma", "Allii Macrostemonis Bulbus-->Parched Ziziphi Spinosae Semen", "Draconis Os-->Ostreae Concha", and "Salviae Miltiorrhizac Radix et Rhizoma, Draconis Os-->Ostreae Concha". The core drug combinations included" Chrysanthemi Flos-Gastrodiae Rhizoma-Tribuli Fructus", "Dipsaci Radix-Taxillus sutchuenensis-Achyranthis Bidentatae Radix", and "Margaritifera Concha-Polygoni Multiflori Caulis-Platycladi Semen-Draconis Os".
Drug Interactions
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Drug Therapy, Combination
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Drugs, Chinese Herbal
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chemistry
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history
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therapeutic use
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Entropy
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Heart Diseases
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drug therapy
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history
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History, 20th Century
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History, 21st Century
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Humans
8.Analysis on medication rule in prescriptions for hemoptysis of Menghe physician Ma Peizhi based on knowledge-discovery in database.
Jia-Rui WU ; Wei-Xian GUO ; Xiu-Qin HUANG ; Bing ZHANG ; Xiao-Meng ZHANG
China Journal of Chinese Materia Medica 2014;39(4):627-630
The clinical prescriptions of hemoptysis that built by Menghe physician Ma Peizhi were collected, and were analyzed by the method of unsupervised data mining, such as association rules and clustering algorithm. From the prescriptions, we got the frequency of drugs, the association rules among drugs, 10 core drug combinations and 5 new prescriptions. Accordingly, after the analysis, Menghe physician Ma Peizhi had rich experience in the treatment of hemoptysis. His therapy for hemoptysis was clearing heat and moistening lung, dispel heat from blood to stop bleeding, and enriching yin and blood. And we can also make a conclusion that the TCM inheritance support system is of great practical value for minning the old doctors' clinical experiences.
Data Mining
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Databases, Factual
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Drug Prescriptions
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standards
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Drugs, Chinese Herbal
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chemistry
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therapeutic use
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Hemoptysis
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drug therapy
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Humans
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Practice Patterns, Physicians'
9.Analysis on principle of treatment of cough of yan zhenghua based on apriori and clustering algorithm.
Jia-Rui WU ; Wei-Xian GUO ; Xiao-Meng ZHANG ; Bing YANG ; Bing ZHANG
China Journal of Chinese Materia Medica 2014;39(4):623-626
Based on the data mining methods of association rules and clustering algorithm, the 188 prescriptions for cough that built by Yan Zhenghua were collected and analyzed to get the frequency of drug usage and the relationship between drugs. From which we could conclude the experiences of Yan Zhenghua for the treatment of cough. The results of the analysis were that 20 core combinations were dig out, such as Bambusae Caulis in Taenias-Almond-Sactmarsh Aster. And there were 10 new prescriptions were found out, such as Sactmarsh Aster-Scutellariae Radix-Album Viscum-Bambusae Caulis in Taenian-Eriobotryae Folium. The results of the analysis were proved that Yan Zhenghua was good at curing cough by using the traditional Chinese medicine that can dispel wind and heat from the body, and remove heat from the lung to relieve cough.
Algorithms
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Cough
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drug therapy
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Data Mining
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Drug Prescriptions
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Drug Therapy, Combination
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Drugs, Chinese Herbal
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therapeutic use
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Humans
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Practice Patterns, Physicians'
10.Analysis on medication rules of state medical master Yan Zhenghua from prescriptions with citri reticulatae pericarpium based on data mining.
Jia-Rui WU ; Wei-Xian GUO ; Bing ZHANG ; Xiao-Meng ZHANG ; Bing YANG ; Xiao-Guang SHENG
China Journal of Chinese Materia Medica 2014;39(4):618-622
The prescriptions containing pericarpium citri reticulatae that built by Professor. Yan were collected to build a database based on traditional Chinese medicine (TCM) inheritance assist system. After analyzed by data mining, such as apriori algorithm, the frequency of single medicine, the frequency of drug combination, the association rules between drugs and core drug combinations can be get from the database. Through the analysis of 1 027 prescriptions with pericarpium citri reticulatae, these prescriptions were commonly used to treat stomach aches, cough and other syndromes. The most frequency drug combinations were "Citri Reticulatae Pericarpium-Poria", "Paeoniae Radix Rubra-Citri Reticulatae Pericarpium" and so on. The drug association rules that the confidence was 1 were "Glycyrrhizae Radix ex Rhizoma --> Citri Reticulatae Pericarpium", "Paeoniae Alba Radix-Cyperi Rhizoma --> Citri Reticulatae Pericarpium", "Poria --> Citri Reticulatae Pericarpium", and so on. The drugs in the prescriptions containing pericarpium citri reticulatae that built by Professor Yan mostly had the effects of regulating the flow of Qi and invigorate blood circulation, which reflected the clearly thought when making prescriptions.
Citrus
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chemistry
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Data Mining
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Drug Interactions
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Drug Prescriptions
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Drug Therapy, Combination
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Drugs, Chinese Herbal
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pharmacology
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Humans
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Practice Patterns, Physicians'