1.Impacts of different intervention on the effects of patients with hypertension
Chinese Journal of Primary Medicine and Pharmacy 2010;17(z2):20-21
Objective To investigate and compare the impacts of health education and psychological intervention on the clinical effects of patients with hypertension. Methods 102 hypertension cases were collected and were randomly divided into three groups, health education group (36 cases), psychological intervention group (30 cases) and comparison group (36 cases). Compliance with prescription,anxiety level and blood pressure were observed both before and after the health education and psychological intervention. Result After health education,compliance with prescription in health education group was significantly improved ( P < 0. 01 ), and blood pressure control of health education group was more preferable than the comparison group ( P < 0. 01 ). After psychological intervention,anxiety level in psychological intervention group was significantly decreased ( P < 0. 05 ), and blood pressures control of psychological intervention group was more preferable than the comparison group ( P < 0. 01 ). Blood pressures had no statistical significance between health education group and psychological intervention group. Conclurion Health education could improve compliance with prescription, and paychological intervention could improve patients' mentl health, and both of them were conducive to the control of blood pressure of patients.
2.Carcinosarcoma of common bile duct: report of a case.
Chinese Journal of Pathology 2006;35(3):192-192
3. Clinical observation on change of immunological function after chemotherapy in combination with ubenimex for malignant tumors
Tumor 2013;33(4):382-384
Objective: To explore the effect of chemotherapy in combination with ubenimex on immunological function of patients with malignant tumors. Methods: The changes of counts of T-lymphocyte subsets and NK (natural killer) cells in peripheral blood of patients with malignant tumors after chemotherapy alone (n = 150) or in combination with ubenimex (n = 150) were examined by FCM (flow metry). Results: The proportions of CD3+ and CD4+ T-lymphocyte subsets, NK cells (CD3-/CD16+ CD56 +) and the ratio of CD4+/CD8+ in peripheral blood of patients with malignant tumors after chemotherapy in combination with ubenimex were significantly higher than those of patients receiving chemotherapy alone (P < 0.05). The proportion of CD8+ T-lymphocytes was obviously lower in patients receiving chemotherapy in combination with ubenimex than that in patients receiving chemotherapy alone (P < 0.05). Conclusion: Use of ubenimex may improve the immunological function of patients with malignant tumors after chemotherapy. Copyright © 2013 by TUMOR.
5.Significance and Assaying of Serum Interleukin-1?,Interleukin-6,Interleukin-8 and Tumor Necrosis Factor-? in Highly Pathogenic Avian Influenza Viral Pneumonia in Mice
hong-xia, ZHAO ; xian-zhu, XIA ; ji-rong, LU
Journal of Applied Clinical Pediatrics 2006;0(16):-
Objective To study the interrelation between highly pathogenic avian influenza viral pneumonia(HPAIVP) and cellular factors interleukin-1?(IL-1?),interleukin-6(IL-6),interleukin-8(IL-8)and tumor necrosis factor-?(TNF-?) in HPAIVP.Me-thods Sixty Kunming mice were divided into 2 groups randomly:experiment group and control group,each group consisted of 30 mice.The highly pathogenic avian influenza virus was used to establish HPAIDP models.The expressions of serum IL-1?,IL-6,IL-8 and TNF-? in experiment group of different moment and control group were detected by enzyme linked immunosorbent assay(ELISA).Result The levels of serum IL-1?,IL-6 and TNF-? in experiment group were significantly higher than those in control group(Pa
7.Extramammary Paget's disease due to underlying anal canal adenocarcinoma.
Shan-xian LOU ; Li-xia WANG ; Hong-qi SHI
Chinese Journal of Pathology 2006;35(11):701-701
Adenocarcinoma
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metabolism
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secondary
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surgery
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Anal Canal
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chemistry
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pathology
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surgery
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Anus Neoplasms
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metabolism
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pathology
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surgery
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Carcinoembryonic Antigen
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analysis
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Diagnosis, Differential
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Humans
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Immunohistochemistry
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Keratin-20
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analysis
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Male
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Middle Aged
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Mucin-1
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analysis
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Paget Disease, Extramammary
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metabolism
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secretion
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surgery
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Skin Neoplasms
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metabolism
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secretion
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surgery
9.Two Species of Paragonimus Examined in the Potamon Soid by Mengla Market
Wenlin WANG ; Lin LEI ; Benjiang ZHOU ; Daiguang XIA ; Xian ZHANG
Journal of Kunming Medical University 2001;22(1):27-29
The potamon that were sold by Mengla market were examined positive for two species of paragonimus metacercariae andexcyted metac ercariae, this is the first report in Yunnan Province. The potamon that were sold by cities market from other suburbs may cause epdemic or outbreak of paragonimiasis, there is of momentous significance in epidemiology.
10.Comparison of the efficacy and safety between the use of ropivacaine alone and ropivacaine with sufentanil in epidural labor analgesia
Xian WANG ; Fan XIA ; Shanwu FENG ; Shiqin XU ; Xiaofeng SHEN
The Journal of Clinical Anesthesiology 2016;32(8):761-764
Objective To compare the analgesic efficacy and safety of the sole local anesthetic ropivacaine with the combination of both local anesthetic ropivacaine and opioidergic analgesic sufen-tanil given epidurally on the labor pain control.Methods After institutional review board approval and patient consent,a total of 481 nulliparas requesting epidural labor analgesia were randomized into two groups:a sole local anesthetic group (0.125% ropivacaine,group R)and a combination of local anesthetic and opioidergic analgesic group (0.125% ropivacaine+0.3 μg/ml sufentanil,group RS). Analgesic efficacy was measured using numerical rating scale (NRS)of pain and maternal visual ana-logue scale (VAS)analgesia satisfaction with regard to the first and the second stage of labor.Anal-gesic safety was measured with the Bromage scale of maternal safety and epidural labor analgesia re-lated side effects,as well as fetal safety including Apgar scoring and umbilical cord artery blood gas a-nalysis.Results A total of 346 participants completed the study,with 1 64 and 182 women in each group R and RS,respectively.The median NRS pain score during the first stage of labor was signifi-cantly lower in the combination group (2.2,IQR:1.8-2.7 )comparing to the sole local analgesic group (2.4,IQR:2-2.8)(P <0.001).No significant difference was observed in NRS pain score dur-ing the second stage of labor.Patients in both groups were rated the same VAS satisfaction of analge-sia.Patients in the sole local analgesic group experienced fewer side effects than those in the combina-tion group (37.7% versus 47.2%,P =0.082).The incidence of 1-min Apgar≤7 was lower in the sole local analgesic group 2 (1.2%) than the combination group 10 (5.5%) (P < 0.05 ). Conclusion The sole local anesthetic ropivacaine produces a comparable labor analgesic effect as the combination of both local anesthetic ropivacaine and opioidergic analgesic sufentanil but the former has less maternal side effects,and less incidence of lower 1-min Apgar scoring.