Diplopia ; etiology ; Fracture Fixation ; adverse effects ; methods ; Humans ; Orbital Fractures ; diagnosis ; diagnostic imaging ; surgery ; Orbital Implants ; Tomography, X-Ray Computed

Objective To study the chemical constituents in ethanol extract from the carpophore of Xanthoceras sorbifolia and explore a new potential part.Methods The constituents were isolated by macroporous resin and silica gel column chromatography and their structures were elucidated by the phisi-cochemical properties and spectral evidence.Results Compounds Ⅰ-Ⅵ wre obtained and their structures were identified as 21-angeloyl-24-hydroxy-R1-barrigenol(Ⅰ),23-hydroxybetulinic acid(Ⅱ),3?,23-dihydroxy-lup-20(29) en-28-oic acid-3-caffeate(Ⅲ),22,23-dehydroxy-?-chondrillasterone(Ⅳ),3-oxotirucalla-7,24-dien-21-oic(Ⅴ),and ?-spinasterol-3-O-?-D-glucopyranoside(Ⅵ),respectively.Conclusion Compound Ⅰ is a new natural product and compounds Ⅱ-Ⅳ are isolated from the plants of Xanthoceras Bunge for the first time.

Objectives:To study the effect of triptolide(Tri) on fibroblast cells in vitro culture, morphologically and kinetically. Methods:Light microscope(LM)and electron microscope(EM)were employed to detect the morphological changes in Tri group. Cell DNA content and apoptosis were assayed by flow cytometry (FCM). Results:In Tri group, fibroblast cells showed less density, slimmer body, abnormally and typical apoptosis under LM, while rarefaction and content of rough endoplasmic reticulum(RER) decrease, and apoptosis in different stages could be seen under EM. In FCM,AI elevated remarkably in Tri groups, and the effect is dose dependent, with cell cycle uninfluenced at all. Conclusions:The mechanism of triptolide on hypertrophic scars is related to its promotion on fibroblast apoptosis and inhibition of collagen excretion.

Adult ; Arterial Occlusive Diseases ; etiology ; Arteritis ; complications ; Coronary Artery Disease ; etiology ; Female ; Humans

Posterior pedicle fixation-based dynamic stabilization is now densely studied in the non-fusion spine surgery. The method is characterized by the motion preservation of segmental lumbar, avoidance of the stress change after fusion surgery, and adjacent disc degeneration. Posterior pedicle fixation-based dynamic stabilization systems have undergone fast development and are now used for the treatment of degenerative lumbar spine disease. As an innovation of traditional fusion surgery, the clinical evaluation of its efficacy has become a focus of study among spine surgeons. In this paper, we review the recent progress in the clinical efficacy of posterior pedicle fixation-based dynamic stabilization.

Animals ; Electroencephalography ; methods ; Entropy ; Epilepsy ; chemically induced ; physiopathology ; Male ; Nonlinear Dynamics ; Penicillins ; Rats ; Rats, Sprague-Dawley ; Signal Processing, Computer-Assisted

Gout ; therapy ; Humans ; Hyperuricemia ; therapy ; Medicine, Chinese Traditional ; methods

AMPARs are excitatory glutamate receptors that mediate the fast synaptic transmission. AMPARs are homo- or hetero-tetramers composed of selective combinations of four subunits: GluR1, GluR2, GluR3 and GluR4. AMPARs containing GluR2 are mainly in the central nervous system and are Ca2+ impermeable. MPARs-lacking GluR2 are Ca2+ permeable, and GluR2-lacking AMPARs are confined to certain neurons or certain physiological or pathological conditions. Recent research showed that GluR2-lacking AMPARs play special roles in the synaptic function and plasticity and transduction of local signal transduction. This paper reviews the GluR2-lacking AMPARs and their roles in the synaptic function and plasticity.

All previous literatures about Chinese herbal medicines show distinctive traditional Chinese medicine (TCM) flavors. Compendium of Materia Medica is an influential book in TCM history. The TCM flavor theory and flavor standardization principle in this book has important significance for modern TCM flavor standardization. Compendium of Materia Medica pays attention to the flavor theory, explain the relations between the flavor of medicine and its therapeutic effects by means of Neo-Confucianism of the Song and Ming Dynasties. However,the book has not reflected and further developed the systemic theory, which originated in the Jin and Yuan dynasty. In Compendium of Materia Medica , flavor are standardized just by tasting medicines, instead of deducing flavors. Therefore, medicine tasting should be adopted as the major method to standardize the flavor of medicine.
Materia Medica ; standards ; Medicine, Chinese Traditional ; Reference Standards ; Taste

Adult ; Delirium ; chemically induced ; Female ; Humans ; Thiocarbamates ; poisoning