Objective:To systematically describe and analyze the influencing factors of care burden among family caregivers for the disabled elderly.Methods:PubMed, Web of Science, Cochrane Library, EBSCO, CNKI, China Biology Medicine disc, VIP and Wanfang Databases were searched for literatures on the influencing factors of care burden among family caregivers of the disabled elderly. The retrieval period was from establishment of databases to 1 March, 2022. The literature screening, data extraction and quality evaluation were completed by two evaluators. RevMan 5.4 software was used for meta-analysis of data, and descriptive analysis was used for influencing factors that could not be combined.Results:A total of 7 literatures including 3 161 caregivers were included. According to caregiver adaptation model, the associated factors could be grouped into care recipient factors and caregiver factors. The results of meta-analysis showed that the main influencing factors of care burden among family caregivers for the disabled elderly included the degree of disability ( WMD=-10.66, 95% CI: -12.08--9.23, P<0.001), cognitive function ( WMD=3.63, 95% CI: 1.24-6.01, P=0.003), occupational status of caregivers ( WMD=-2.64, 95% CI: -4.35--0.93, P=0.002), self-rating health status ( WMD=12.59, 95% CI: 7.36-17.82, P<0.001), years of care ( WMD=-3.04, 95% CI: -5.15--0.93, P=0.005), length of daily care ( WMD=-4.17, 95% CI: -5.24--3.10, P<0.001) and social support levels ( WMD=-7.20, 95% CI: -10.49--3.91, P<0.001) . Conclusions:The care burden of family caregivers of the disabled elderly is widespread. The degree of disability, cognitive function of the elderly, the occupational status, self-assessed health status, years of care, length of daily care and social support level of the caregivers are the main influencing factors of care burden. Individualized interventions should be tailored to modifiable influencing factors to reduce the burden on caregivers and improve the quality of life of the disabled elderly.