Objective To evaluate the effect of robot-assisted gait training on the walking ability of hemiplegic patients.Methods Sixty hemiplegic patients were randomly divided into a control group and a treatment group,each of 30.Both groups were given traditional rehabilitation and drug therapy.The control group was additionally provided with the traditional gait training,while the treatment group additionally received robot-assisted gait training.The gait training lasted 30 minutes a day,5 days per week.Before and after 8 weeks of training,the time parameters,phase parameters,the joint angles of the lower limbs,and the peak ground reaction forces of both groups were evaluated using a three-dimensional gait analysis system.Results After the intervention,the walking velocity,stride frequency and stride length had increased in the treatment group,while stride width had decreased.Significant improvement was observed in the treatment group in terms of the percentage of swing phase on the paretic side,the percentage of stance phase on the paretic side,the single support time ratio,the percentage of double support phase,the range of motion of the hip and knee joints,and the peak vertical and forward ground reaction force as a percentage of body weight.The improvements were significantly greater than those observed in the control group.Conclusions Compared with traditional walking training,robot-assisted gait training can be more effective in improving the walking ability of hemiplegic patients.

Objective To conduct a comparative study on postoperative complications and patients′quali-ty of life between tension-free inguinal hernia repair with mesh plug(Rutkow operation)and tension-free repair of preperitoneal space with middle incision of lower abdomen(Open TEP operation).Methods A retrospective anal-ysis of 122 cases of inguinal hernia was conducted.And 62 cases of Open TEP operation were concluded into obser-vation group and 60 cases of Rutkow operationinto control group. The basic information of the surgery,postopera-tive complications and the score of quality of life before and after treatment were compared between 2 groups. Results No bladder injury,ductus deferens damage,infections or hematoma on incisions were found after opera-tion and no relapse,patch rejection,infections or atrophia testiculi were seen during the follow-up. The incision pain of observation group lasted shorter than that of control group(P<0.01),while other operational indexes show no great difference(P > 0.05). The incidence of postoperative complications of observation group was 11.29%, much lower than that of control group(P<0.01).Both PCS and MCS scores of 2 groups after treatment increased obviously as compared with those before treatment(P<0.01),but the rise in observation group were more signifi-cant(P<0.01).Conclusion Less postoperative pain and complications,and better life quality are found in the treatment of inguinal hernia with open TEP operation outperforms Rutkow operation.

OBJECTIVE: To examine the expression and clinical significance of the Stat3 and Cyclin D1 in laryngeal squamous cell carcinoma (LSCC). METHOD: The expression of Stat3 and Cyclin D1 in LSCC tissue were detected by the RT-PCR and Western blot method respectively, and then the relationship between Stat3 and Cyclin D1 protein expression level and relevant clinical factors of LSCC was explored. RESULT: Compared to the normal larynx mucosa group, the expression level of Stat3 and Cyclin D1 was significantly higher in LSCC (P < 0.01). The high expression level of Stat3 and Cyclin D1 protein in LSCC was correlated with the clinical stage, tumor differentiation and lymph node metastases (P < 0.01). The expression level of Stat3 was positively correlated with that of Cyclin D1, The correlation coefficient(r) was 0.564 (P < 0.01) for the protein expression and 0.552 (P < 0.01) for the mRNA expression. CONCLUSION Stat3 signaling pathway may play an important role in the tumorigenesis and progression of LSCC. The expression level of Stat3 and its target gene Cyclin D1 can reflect the malignancy degree of LSCC.
Adult ; Aged ; Aged, 80 and over ; Carcinoma, Squamous Cell ; genetics ; metabolism ; pathology ; Cyclin D1 ; genetics ; metabolism ; Female ; Humans ; Laryngeal Neoplasms ; genetics ; metabolism ; pathology ; Male ; Middle Aged ; Neoplasm Staging ; STAT3 Transcription Factor ; genetics ; metabolism