1.Roles of IL-8 and eotaxin in airway inflammation and lung function injury of chronic obstruction pulmonary disease
Chinese Journal of General Practitioners 2011;10(8):579-580
The clinical data of 25 patients with acute exacerbations of chronic obstruction pulmonary disease (AECOPD) admitted from March 2009 to October 2010 were analyzed. The sputum samples were collected and the levels of inflammatory cell, interleukin-8 (IL-8) and eotaxin in sputum were determined. The lung function was measured. Twenty healthy subjects served as controls. The counts of neutrophils and eosinophils, and the levels of IL-8 and eotaxin in sputum of AECOPD were higher than those of health subjects. There was a positive correlation between the levels of IL-8 and the counts of neutrophils (P < 0. 01), and between the levels of eotaxin and the counts of eosinophils in sputum ( P < 0.01). The levels of IL-8 and eotaxin were negatively correlated with the lung function (FEV1% ).
2.Study on psychological health of army talented medical people
Chinese Journal of Behavioral Medicine and Brain Science 2001;10(1):53-54
Objective Analysis and assessment the level of psychological health of army talented medical people. Method Basing on tri-blindness paradigm, 71 talented medical people and controls from different military medical institutions or hospitals were tested with Psychological Health Inventory (PHI). Results There was significant differences between excellent workers and its controls in psychopathic deviate, anxiety, unrealistic, and excellent workers was lower than controls; there was, however, no significant difference in somatization, hypomania, hypochondria, depression. Conclusion Some certain psychological health facts play a important role in those medical talented people' career development and achievement.
3.Advances and clinical application of artificial joint materials in orthopedics
Chinese Journal of Tissue Engineering Research 2007;0(19):-
This study aimed to review the improvement of artificial joint materials to search ideal materials for artificial joint. The developing process of metal artificial joint, high polymer artificial joint, ceramic-made artificial joint and compound material artificial joint was introduced and the material surface processing was explored. Selection of materials for artificial joint is determined by many factors. Each material has the specific benefits and drawbacks, so we can improve their performance by certain processing. Although there are many studies about materials for artificial joint, no ideal material is identified. To develop the materials for artificial joint with high mechanical strength, good biocompatibility, strong abradability and long-term service life is the focus in future bone tissue engineering.
4.Outcomes of mass screening for HIV antibody in Tianjin from 2005 to 2006
Chinese Journal of AIDS & STD 2006;0(04):-
Objective To analyze the data of HIV antibody mass screening in Tianjin from 2005 to 2006 and to evaluate current screening strategy.Methods Confirmation tests were conducted for 601 samples received form HIV screening laboratories in Tianjin in line with the procedures and methods defined by the National Guideline for HIV/AIDS Detection.Results Of the 601 samples,215 were HIV antibody positive(with complete bands);24 samples were positive with special reactive blots,of which 10 cases were followed up with 7 confirmed to be infected with HIV and with 3 confirmed to be excluded;51 samples were uncertain with indeterminate blots,of which 8 cases were followed up and all were proved to be HIV antibody negative.Conclusion Routine HIV screening as part of medical examinations for patients in health care settings or for detained personnel in police and judicial organizations represents an important approach to detect cases of HIV infection,Samples with special reactive blots or indeterminate blots should be handled with caution;they should be followed up and may be tested by other approaches,such as blot test or viral genome detection.
5.General precoder design for mitigation of intercarrier interference in OFDM mobile systems
Journal of Pharmaceutical Analysis 2007;19(1):46-50
For orthogonal frequency-division multiplexing (OFDM) communication systems, the frequency offset in mobile radio channels distorts the orthogonality between sub-carriers, which results in Intercarrier Interference(ICI) and seriously degrades the performance of systems. Based on ICI coefficients analysis, a novel precoder design scheme is proposed for mitigation of ICI. In this technique, precoder matrix is designed by the way of linear counteraction and inserted in the former transmitter signal. Computer simulation results show that this new scheme can effectively reduce ICI and significantly provide the carrier-interference power ratio improvement. Compared with existing ICI mitigation schemes with channel estimation, the proposed scheme has lower computational complexity, and compared with self-cancellation scheme, the bandwidth efficiency can be improved in this proposed scheme. The proposed scheme also has better convergence stability for time-varying frequency selective fading channel.
6.Progress in treatment of childhood atopic dermatitis
International Journal of Pediatrics 2021;48(5):327-330
Atopic dermatitis is a complex chronic, relapsing inflammatory skin disease.Atopic dermatitis in children is usually less severe than in adults, but it is with a high incidence and is susceptible to relapse.Therefore, the physical and mental health of children and their family maybe seriously affected.In the past, the treatments of atopic dermatitis have been limited to glucocorticoids and immunosuppressants.It is unsafe for children because of their toxicities.With the in-depth understanding of pathogenesis, more and more new therapies that focus on intervening in the inflammatory pathway by targeting specific cytokines or their receptors have been found and applied.This article reviews the progress of treatment of the disease to provide new insights for the optimal treatment of atopic dermatitis.
7.The neurohistology of the rotator cuff and capsule of shoulder
Qingsheng ZHU ; Chunming XIA ; Jinyu ZHU
Chinese Journal of Orthopaedics 2001;0(01):-
Objective The articular neurohistology is a new approach to explore stabilized and chronic pain mechanisms for joint research. Furthermore, the distribution of mechanoreceptors and their functional condition play an important role in the movement and stability of joint. The animal experimental study suggest that there is a various characteristics of the type and amount of mechanoreceptors in different joints. Pacini corpuscle, Ruffini corpuscle and Golgi tendon organs as joint mechanoreceptors are widely distributed on nearly all of human joint, and have impact on stabilization of joint. The present investigates the neurohistological features of Pacini corpuscle, Ruffini corpuscle and Golgi tendon organs in the rotator cuff and the capsule, and explores their behaviors for maintaining stability of the shoulder joint. Methods Six rotator cuffs and capsules of shoulder joint were obtained from cadavers died of the accident. The tendinous tissue of subscapularis, supraspinatus、infraspinatus, and teres minis were resected from the interface of tendon and muscle to great and lesser tuberosity of humerus, the capsule tissues of glenohumeral were harvested as well. Then, the tissues were cut into a small fragments fixed with the formalin buffer solution, and embed in paraffin. The section was made along the longitudinal axis of the tendon at 150 ?m interval with Leitz 1516 machine. The modified Bielschowsky staining and the S-100 immuohistochemical staining were adopted to observe the mechanoreceptors of Pacini corpuscle, Ruffini corpuscle and Golgi tendon organs. The distribution density and size of the sensitive nerve endings were analyzed with Leica imaging process system. Results The tendinous part of rotator cuff could be divided into three layers: synovial, intermediate and articular layer. The morphology of the these three types of mechanoreceptors, Pacini corpuscle, Ruffini corpuscle and Golgi tendon organs, could be identified clearly in the every layer of the tendious tissues under microscopic examination. Pacini corpuscle was ellipse and had multi layer capsule with the thickness of 20-40 ?m; Ruffini corpuscle was columnar and 350-550 ?m in size; Most of Golgi tendon organs were found at the interface of tendon and muscle. Among of them, the Pacini corpuscle and Ruffini corpuscle were much more than the Golgi tendon organs in rotator cuff and capsule of shoulder. The results of immuohistochemical staining and the counting of nerve ending assisted by the computer showed the number of sensory nerve endings in the subscapularis, supraspinatus and anterior capsule of the shoulder were much more than in the infraspinatus, teres minis and posterior capsule. The diameter of nerve bundle in the subscapularis, supraspinatus and anterior capsule was thicker than in the other periarticular structures. In periarticular structures, the mean value of nerve fiber counting were 25 in infraspinatus, 25 in supraspinatus, 13 in subscapularis, 10 in teres minis, 22 in anterior capsule and 12 in posterior capsule. Conclusion Shoulder capsule and rotator cuff are rich in the three type of mechanoreceptors, Pacini corpuscle, Ruffini corpuscle and Golgi tendon organs. However, there are a different distribution density and size of them in rotator cuff and capsule of shoulder, but the three of mechanoreceptors are mainly concentrated in the subscapularis, supraspinatus and the anterior capsule. S-100 immuohistochemical staining is much more sensitive than the modified Bielschowsky silver staining in displaying the innervations of the rotator cuff and capsule. The characters of the sensory nerve ending distribution in shoulder imply that the innervations of the shoulder play an important role in keeping the stability and mobility of the shoulder.
8.Reliability and validity of idol worship scale in college students
Zhibing YANG ; Jieqiong GUO ; Liang XIA ; Xia ZHU
Chinese Journal of Behavioral Medicine and Brain Science 2012;21(1):89-91
ObjectiveTo develop the scale on idol worship for college students.Methods54 items were determined by reviewing items in relating literatures and scales,interview and panel discussion.Then about 110,182 and 277college students were picked out randomly as samples from colleges of Guangzhou.Item analysis,exploratory factor analysis,reliability analysis and confirmatory factor analysis were used to analyse the data.ResuitsIdol worship scale comprised four subscales:fascination,rational knowledge,the degree of concern and behavioral modification.The scale was comprised of 20 items,and the factor loading of the items ranged from 0.552 to 0.841.Cronbach's α coefficient of the four subscales were 0.894,0.715,0.769,0.758,and the Cronbach's α coefficient of the scale was 0.889.Confirmatory factor analysis showed a higher goodness of fit( RESEA =0.064,GFI =0.89,NFI =0.96,NNFI =0.98,CFI =0.98,IFI =0.98 ).ConclusionThe idol worship scale has good psychometric properties,and can be used as a measurement tool for measuring the idol worship of college students.
9.Significance and Assaying of Serum Interleukin-1?,Interleukin-6,Interleukin-8 and Tumor Necrosis Factor-? in Highly Pathogenic Avian Influenza Viral Pneumonia in Mice
hong-xia, ZHAO ; xian-zhu, XIA ; ji-rong, LU
Journal of Applied Clinical Pediatrics 2006;0(16):-
Objective To study the interrelation between highly pathogenic avian influenza viral pneumonia(HPAIVP) and cellular factors interleukin-1?(IL-1?),interleukin-6(IL-6),interleukin-8(IL-8)and tumor necrosis factor-?(TNF-?) in HPAIVP.Me-thods Sixty Kunming mice were divided into 2 groups randomly:experiment group and control group,each group consisted of 30 mice.The highly pathogenic avian influenza virus was used to establish HPAIDP models.The expressions of serum IL-1?,IL-6,IL-8 and TNF-? in experiment group of different moment and control group were detected by enzyme linked immunosorbent assay(ELISA).Result The levels of serum IL-1?,IL-6 and TNF-? in experiment group were significantly higher than those in control group(Pa