1.Changes in brain natriuretic peptide levels before and after Capoten test as well as renal artery intervention in patients with suspected renal artery stenosis
Xia YANG ; Luyue GAI ; Qinhua JIN
Chinese Journal of Tissue Engineering Research 2007;0(39):-
Forty patients with hypertension suspected to stenosis of renal artery were selected from Department of Cardiology, General Hospital of Chinese PLA between June 2007 and March 2008, including 28 males and 12 females with an average age of (60.0?15.6). Capoten test and renal artery angioplasty were performed in all patients to detect brain natriuretic peptide changes before and after the Capoten test and renal artery stent implantation. Among 40 patients underwent Capoten test, 30 showed positive result and 10 negative. The levels of brain natriuretic peptide before and after Capoten test in patients with positive result were statistically different (P 0.05). Among thirty patients with positive Capoten test undergoing renal artery angioplasty, twenty-three patients underwent stent implantation, and their brain natriuretic peptide showed statistical differences between before and after stent implantation (P 0.05). The results of the study show that levels of brain natriuretic peptide can be used to evaluate possible effect of stent implantation for patients with hypertension suspected to stenosis of renal artery.
2.Efficacy of Long xue jie capsule combined with Badger Oil treatment of radiotherapy -induced injuries of skin
Xia WU ; Longxian GAI ; Xuejiang LIU
Chinese Journal of Primary Medicine and Pharmacy 2015;(11):1719-1721
Objective To evaluate the effects of Long xuejie capsule combined with Badger Oil on head and neck cancer radiotherapy -induced radiation injuries of skin application value.Methods The received radiation therapy in Ⅱ -Ⅳacute radioactive skin injury in 128 cases were selected.Used the envelope method,they were ran-domly divided into the research group and the control group.Outside the team starts from a radioactive dermatitis with badger oil apply skin irradiation area,with a dragon dragon's blood powder coating outside skin area.Apply 1 -2 times a day,seven days for a course of treatment until wound healing.The control group from a radioactive dermatitis with 0.9% sodium chloride injection,dexamethasone,gentamycin gauze wet moist wound after 30min,1 -2 times a day, 7 days for a course of treatment.Compare the therapeutic effect of the two groups of wet radioactive dermatitis and interruption of radiotherapy and skin lesion healing time.Results The effective rate of the study group was 90.6%, the cure rate was 100%.The effective rate of the control group was 80%,the treatment rate was 62.5%.There was a significant difference between the two groups (χ2 =14.64,11.86,11.48.P <0.01).The vast majority of the study group in a week skin lesions healed,no patients discontinued radiotherapy,the control group 13 cases of termination of radiotherapy,interruption time study group (3.8 ±1.4)d,group interrupt time (8.8 ±1.6)d,lesion healing time of the study group (5.6 ±0.6)d,lesion healing time in the control group (10.6 ±0.8)d.There was a significant differ-ence between the two groups (χ2 =6.68,6.95,11.48,all P <0.05,significant difference).Conclusion Longxuejie capsule combined Badger Oil has significant efficacy in the treatment of radioactive skin injury.It could shorten the healing time,and the method is convenient,economic,security and has certain clinical value.
3.Analysis of risk factors for gallbladder polyps in shift work nurses
Li GAI ; Tianhui XIA ; Ling FAN
Chinese Journal of Practical Nursing 2021;37(9):707-711
Objective:To analyze the detection of gallbladder polyps among shift nurses in Shengjing Hospital of China Medical University in physical examination and its related influencing factors, so as to provide scientific basis for shift nurses to prevent gallbladder polyps.Methods:A total of 1 119 shift nurses who had physical examination in Shengjing Hospital of China Medical University from January 1 to March 31, 2018 were selected. The patients with gallbladder polyps diagnosed by ultrasound were included in the case group, and those without gallbladder polyps were taken as the control group. Age, gender, body mass index (BMI), night shift frequency, education level, Department, meal regularity, drinking history, smoking history, serum triglyceride, serum total cholesterol, hepatitis B surface antigen, serum alanine aminotransferase and serum aspartate aminotransferase levels were compared between the two groups.Results:Univariate analysis showed that age ( P<0.001), gender ( P=0.028), BMI ( P=0.005), night shift frequency ( P=0.021) were the factors with statistically significant difference between the case group and the control group. There were no statistically significant differences between the case group and the control group in terms of education level, department, dining regularity, drinking history, smoking history, hepatitis B surface antigen, serum triacylglycerol, serum total cholesterol, serum alanine aminotransferase, serum aspartate aminotransferase levels ( P>0.05). Logistic regression analysis showed that age, BMI and night shift frequency were the influencing factors in the regression equation ( P<0.05). Conclusion:Age, BMI and night shift frequency may be related risk factors of gallbladder polyps in shift nurses.
4.Correlation of Videodensitometric Scale and Single Photon Emission Computerized Tomography in Assessment of Myocardial Microperfusion
Xia YANG ; Yundai CHEN ; Hongbin LIU ; Luyue GAI
Chinese Journal of Rehabilitation Theory and Practice 2010;16(11):1034-1035
ObjectiveTo evaluate the feasibility and the value of videodensitometric scale (VDS) in assessing myocardial microperfusion. Methods11 Beagles were embolized small coronary artery with polystyrene microbubble (100 μm). Coronary angiography was performed after the embolization and the VDS was calculated. Single photon emission computerized tomography (SPECT) was also performed after embolization and SPECT scores were also calculated. ResultsVDS after embolization was (15.2±3.8); and SPECT score was (17.6±6.4). VDS correlated negatively with SPECT scores (r=-0.85, P<0.05).ConclusionVDS keeps a closely correlation with SPECT. It can be used to assess myocardial microcirculation in clinical.
5.Experimental Study of Videodensitometric Scale to Assess Myocardial Microperfusion
Xia YANG ; Hongbin LIU ; Luyue GAI ; Luoshan DU ; Lijun WANG
Chinese Journal of Rehabilitation Theory and Practice 2008;14(2):138-140
Objective To evaluate the feasibility and the value of videodensitometric scale(VDS)assessing myocardial microperfusion.Methods The small coronary arteries of 11 dogs were embolized by ejecting polystyrene microbubble(dm= 100 μm),six embolized at left anterior descending branch(LAD)and five embolized at left circumflex branch(LCX).Coronary angiography was performed before and after the embolization.The myocardial contrast echocardiography(MCE)was performed in 12th hour after embolization.VDS was calculated according to coronary angiography.MCE scales were calculated.Results Among the eleven experimental dogs,VDS before embolization was 24.4±4.9 and that after embolization was 15.2±3.8.VDS after embolization was obviously lower than before embolization(P<0.05).VDS between LAD and LCX at the same stage was no difference;MCE scores after embolization were 7.6±2.4.VDS was negatively dependent with MCES after embolization(γ=-0.78,P<0.05).Conclusion As a newly quantitative index and keeping a closely correction with MCE,VDS can be used as a quantitative index to assess myocardial microperfusion in clinic.
6.Initial Application of Video Density Scale to Assess Myocardial Microperfusion
Xia YANG ; Hongbin LIU ; Luoshan DU ; Luyue GAI ; Lijun WANG
Chinese Journal of Rehabilitation Theory and Practice 2007;13(3):279-280
Objective To evaluate the feasibility and the value of video density scale (VDS) for assessing myocardial microperfusion.MethodsVDS and corrected TIMI frame counted (CTFC) were calculated and compared in 58 cases undergoing coronary catheter angiography.ResultsVDS of 58 cases was (22.5±5.8)and 95% confidence interval of normal myocardial microperfusion is(20.2,24.7).The CTFC was (21.1±4.5).It showed negative correlation between VDS and CTFC.ConclusionVDS is feasible to assess myocardial microperfusion quantificationally.The possibility of myocardial microperfusion dysfunction would be increased when VDS is lower than 20.
7.Observation on double - passage annular lacrimal intubation for canalicular laceration
Gui-Ping, LI ; Yan, SHAO ; Xiao, LI ; Yu-Huan, YUE ; Gai-Xiu, XIA
International Eye Science 2014;(9):1726-1727
To evaluate the value of silicone intubation and ring-fixed method in canalicular laceration.
●METHODS: A retrospective study of 36 cases with laceration of lacrimal canaliculus. For all the patients, microscope was used to find the broken ends of the lacrimal canaliculus, and then straight insertion was performed to the distant and near broken ends through the upper and lower lacrimal points, then passed the dacryocyst to insert nasolacrimal canal and ended up in inferior nasal meatus. Thus, clinical data about forming annular support to treat laceration of lacrimal canaliculus was presented here.
● RESULTS: All 36 patients with traumatic canalicular laceration were anastomosed successfully and all patients healed without infection. The surgery went well, intubation was smoothly, all patients were followed - up for another 6mo after the stent was removed. The accidental fall off of the stent was not observed during the follow - up. During the follow - up 10 - 18mo after extubation, when the stent was removed, 32 cases (88. 9%) recovered to normal lacrimal drainage function;4 cases ( 11. 1%) remained epiphora with obstructed lacrimal passage. All cases were no lower eyelid ectropion.
●CONCLUSlON: For the patients with inferior canalicular laceration, the silicone intubation and ring-fixed method is effective, low irritation and less complication.
8. Molecular identification of hippocampus and its adulterants based on COI barcode
Chinese Pharmaceutical Journal 2015;50(17):1469-1473
OBJECTIVE: To establish an accurate identification method of genuine Hippocampus based on COI sequences as DNA barcodes and analyze the relationship between the genuine and adulterants of Hippocampus. METHODS: Two hundred and e-leven pieces of COI sequences were collected from 21 Hippocampus species in this study. After PCR amplification and sequencing of the DNAs, the DNA barcoding gap and phylogenetic cluster analysis were carried out. RESULTS: The COI sequences of the five authentic species all had obvious DNA barcoding gap. For phylogenetic cluster analysis, all of the samples were monophyletic and every species could be discriminated clearly. CONCLUSION: COI is an effective DNA barcode for the identification of the genuine Hippocampus and its adulterants, and have important significance for clinical medication safety.
9. Effects of inflammatory pain on inflammatory reaction and expressions of TNF-α and MCP-1 in peripheral tissue of mice
Journal of Xi'an Jiaotong University(Medical Sciences) 2019;40(1):65-70
Objective: To investigate the effects of inflammatory pain on local tissue structure, inflammatory reaction and expression levels of TNF-α and MCP-1 in formaldehyde-induced inflammatory pain in mice. Methods: Sixty-four adult male mice were randomly divided into NS group (40 μL of saline injected into the wrist of right forelimb), FCOH group (50 mL/L formaldehyde of 40 μL injected into the wrist of right forelimb), L group (5 μg/mL lidocaine of 0.3 mL for brachial plexus anesthesia) and FCOH+L group. Some of the tissue samples were collected at 48 h after formaldehyde modeling to observe the infiltration of inflammatory cells by HE staining. The rest were used to assess the expression levels of TNF-α and MCP-1 by Western blot. Results: Compared with NS group, FCOH group showed peak inflammatory response at 24 h (thickness of injection sites: 1.73 mm vs. 4.02 mm, temperature: 37 ℃ vs. 38.3 ℃, P<0.05). However, FCOH+L group showed intense inflammatory responses at 48 h (thickness of injection sites: 1.68 mm vs. 5.10 mm, temperature: 37 ℃ vs. 38.5 ℃, P<0.05). Furthermore, after 48 h FCOH group had a lower degree of infiltration of inflammatory cells and higher expression levels of TNF-α and MCP-1 than those in FCOH+L group (P<0.05). Conclusion: Inflammatory pain plays a significant role in the healing process of injured issues by facilitating the local inflammation and affecting the duration. The expression levels of TNF-α and MCP-1 in local tissues decrease by interrupting the transmission of pain.
10.Surveillance of Antimicrobial Resistance in Staphylococcus spp and Enterococcus spp
Xiaoping XU ; Xia GAO ; Xiaoxia CHI ; Junhui GAI ; Hui AI ; Zhuocheng LI
Chinese Journal of Nosocomiology 2006;0(03):-
OBJECTIVE To analyze the resistant rates of Staphylococcus spp and Enterococcus spp isolated from clinical infections to antibiotics,and to provide reference method for effective control infections of Staphylococcus.METHODS The Staphylococcus spp and Enterococcus spp were identified with VITEK-32 automicrobiology system(AMS) and GPI card,drug resistance was detected with VITEK-32 AMS and GPS-107 card.Laboratory data were analyzed by WHONET-5 statistic software.RESULTS Among 1 445 Staphylococcus spp and Enterococcus spp strains isolated from clinical samples,330 strains(22.8%) were Staphylococcus aureus,872 strains(60.3%) were coagulase negative Staphylococcus,213 strains(14.7%) were Enterococcus faecalis,and 30 strains(2.1%) were E.faecium.From S.aureus 223 strains(67.6%) were MRSA,718 strains(82.3%) of coagulase negative Staphylococcus were MRCNS.The detectable rates of MRSA and MRCNS in 2004 were 75.3% and(82.3%,) which were higher than those in 2003(48.4% and 78.4%).Neither strains of S.aureus nor strains of coagulase negative Staphylococcus were found resistant to vancomycin.MRSA and MRCNS resistant rates were found(higher) than MSSA and MSCNS.From the isolated strains of E.faecalis in 2004,the resistance rates to(ciprofloxacin,) nitrofurantoin,gentamicin-500,levofloxacin,and penicillin G were found higher than that in 2003.(E.faecium)(resistant) rates were found significantly higher than E.faecalis.CONCLUSIONS Staphylococcus spp and Enterococcus spp are the main pathogens leading to clinical infections.The findings of these(surveillance)(studies) will enhance our knowledge regarding the problem of antimicrobial resistance and will serve as a basis for future policies and practice styles.