Objective To investigate the effect of Dougenguanshitong oral liquids (DGGST) on the treatment of esophageal carcinoma model rats. Methods Esophageal carcinoma rats model were made by Wistar rats that were treated with MANA 5 mg/kg (s.c. once weekly) for 20 weeks. Control group were given Ftorafur. The rats were sacrificed to examine esophageal carcinoma histopathology change under sight and microscope after treated by DGGST. Result The morbidity and canceration rate of tumour of all Chinese medicine treated groups and chemotherapy group were lower than the model group. The difference between each Chinese medicine treated group and chemotherapy group was remarkable (P

Objective To evaluate the influence of Bisoprolol on the cariac function and heart rate of in the cor pulmonale patients with heart failure. Methods 55 heart failure patients associated with cor pulmonale were randomly divided into two groups. The patients of treatment group(n=35) were orally given. The patients of control group(n=20) only received routine therapy. Bisoprolol except routing therapy. During the treatment the changes of cariac function and heart rate of all patients were observed, and before the Bisoprolol treatment and at 6th and 12th weeks after Bisoprolo treatment, the levels of creatinine, uricemia(UA), total cholesterol(TC), triglyceride(TG), high density lipoprotein cholesterol(HDL-C), and fasting plasma glucose were measured. Results In Bisoprolol treatment group the total effective rate was 94 3%, and was 75% in the control group(P0 05). Conclusion The ? 1-receptor blocker Bisoprolol was effective, and safe for treating the heart failure associated with cor pulmonale.

Objective To investigate the relationship between metabolic syndrome and related factors and recurrence of ischemic stroke.Methods 90 in-and out-patients with ischemic stroke in Jiangbei District Hospital of Traditional Chinese Medicine during May 2013 and May 2014 were enrolled.In 90 cases,4 patients with cerebral hemorrhage were excluded.Basic data of the 86 patients were investigated,which including gender,age,abdominal circumference,smoking,drinking,family history of stroke,diabetes,hypertension,hyperlipidemia,a history of atrial fibrillation,transient ischemic attacks,fasting blood glucose,triglyceride,cholesterol,uric acid,homocysteine,urinary protein-creatine ratio,carotid ultrasound examination.We investigated patients with or without recurrent stroke during one year of telephone visit and follow-up.Patients with recurrent stroke were investigated.Results During the one year follow-up,24 cases in the 86 patients with ischimic stroke were recurrent,the recurrence rate was 27.9 ％.2 cases in the recurrent patients died because of massive cerebral infarction,accounted for 8.3％ of the patients with recurrent stroke.According to Chi-square test,smoking,high fasting plasma blood glucose,hypertension,elevated low density lipoprotein cholesterol,high uric acid,high homocysteine and carotid atherosclerosis all had correlation with recurrent stroke(P＜0.05).In this logistic-regression model,smoking,high fasting plasma blood glucose,hypertension,elevated low density lipoprotein cholesterol,high uric acid,high homocysteine and carotid atherosclerosis were all predictors for recurrence of ischemic stroke.Conclusion Cntrolling the risk factors after the first stroke as a long term strategy has important clinical significance for secondary prevention of ischemic stroke.

Changes in the cytotoxicity of tetrandrine before and after liposome encapsulation on rat alveolar macrophages in vitro were ohserved. Results suggested that there was a siginificant differentiation on the adsorptive capacity to yeast, and the level in cytoplasmic free calcium and potassium, and the cytoskeletal control of macrophages at the concentration of 40?g/ml. Experiments showed that liposome encapsulation may attenuate cytotoxicity of tetrandrine.

Adult ; Humans ; Orthodontics, Corrective ; methods ; Periodontium

Biomedical Research ; Child, Preschool ; China ; Humans ; Pediatrics

Objective To investigate the bacterial distribution and resistance of clinical isolates ,so as to provide basis for the clinical medication .Methods The drug susceptibility testing was performed by Kirby‐Bauer method or automated system .The re‐sults were analyzed by WHONET 5 .6 referring to the breakpoints of CLSI 2013 .Results Of 1 240 clinical iso1ates ,the gram‐posi‐tive cocci and gram‐negative bacteria accounted for 32 .7% and 67 .3% respectively .The top five of isolated strains were Escherichia coli ,Klebsiella spp ,coagulase negative staphylococci ,Staphylococcus aureus ,Streptococcus pneumonia;the first five of isolated spec‐imens constitute followed by sputum ,urine ,blood ,secretions and stool .The average prevalence of methicillin‐resistant strains in S . aureus (MRSA) and coagulase‐negative Staphylococcus (MRCNS)was 17 .1% and 74 .7% ,respectively ;no vancomycin ,teicoplanin or linezolid‐resistant strains were found;no vancomycin‐resistant strains were found in Enterococcus spp;Enterobacteriaceae was still highly susceptible to imipenem and meropenem (> 85% );extended spectrum beta‐lactamases(ESBLs) producing strains ac‐counted for 56 .7% of Escherichia coli ,and accounted for 18 .6% of Klebsiella pneumonia;the drug resistance rates of Pseudomonas aeruginosa to imipenem was 11 .9% .The drug resistance rates of Acinetobacter spp to imipenem was 19 .0% .Conclusion The main infection site of patients in this hospital is respiratory tract and attention should be paid to docimastic sample .The top five clinical i‐solates and drug resistance are roughly the same with the results of Chongqing drug resistance monitoring net .

The procedure for Rhizoma Pinelliae(Processed with Licorice and Lime) was combinatively evaluated by L_9(3)~4 orthogonal design with three factors:decocting times for Radix Glycyrrhizae,concentrated volume of decoction and macerating time. The optimum condition is as follows: each 100g of Rhizoma Pinelliae,accompanied with 15g of Radix Glycyrrhizae (decocted with water for two times,then the two decoctions were combined,and concentrated to 150ml.)and 10g of calx,was macerated in concentrated decoction of Radix Glyeyrrhizae for six days

Education, Medical, Continuing ; methods ; Evidence-Based Medicine ; Humans ; Pediatrics ; Periodicals as Topic ; Physicians ; Problem-Based Learning

Child ; Humans ; Immunologic Deficiency Syndromes