1.Behavioral research on the influence of anxiety on risk decision-making
Yuqing TIAN ; Lefei TENG ; Xuezhi HONG ; Yan LIU ; Xi TAN
Chinese Journal of Behavioral Medicine and Brain Science 2015;24(9):835-837
Objective To explore the differences in behavior of anxiety individuals and the normal control under different feedback (positive feedback,negative feedback).Methods 400 university students were investigated using self-rating anxiety scale(SAS) and state anxiety inventory (SAI) and the data were analyzed with balloon analogue risk task.Results The score of anxiety group(24.28±6.12) was significantly lower (t=-2.25,P<0.05) than that of control group(29.80±7.26) in the number of busting balloons.But in the number of busting balloons of positive and negative feedback condition,scores of anxiety group and control group were not significantly different(t=-1.82,P>0.05;t=-1.78,P>0.05).Conclusions Influence of anxiety on decision-making often manifests as risk aversion.
2.Surgical treating experience of lower eyelid longitudinal laceration combined with lower lacrimal canaliculi disruption
Meng-Fei, WANG ; Xi-Dong, YAN ; Guang-Hong, ZHANG ; Yan-Ming, TIAN ; Peng, LI ; Lei, QIAO
International Eye Science 2014;(10):1898-1900
AIM: To discuss the clinical applications of methods to localize nasal cut ends and the effects of Z-plasty in the surgeries for lower eyelid longitudinal laceration combined with lower lacrimal canaliculi disruption.
METHODS: From September, 2010 to October, 2013, a total of 37 patients ( 37 eyes ) with lower eyelid longitudinal laceration combined with lower lacrimal canaliculi disruption were operated for anastomosis of lacrimal canaliculi disruption and suture of lower eyelid longitudinal. Different methods to search for the nasal cut ends of lacerated lacrimal canaliculi, such as “under a microscope directly”, “guided by probing needle” and“pigtail curved probe”. Then, to repair lower eyelid longitudinal laceration with Z-plasty transposition flaps. Follow up was 3mo~2a after operation.
RESULTS: All nasal cut ends could be found successfully on 37 patients;Lacrimal duct unobstructed in 31 patients (83. 8%), improved in 5 patients (13. 5%), invalid in 1 patient (2. 7%),the overall successful rate was 97. 3%; the eyelids repair was satisfactory, small scars, the appearance and function was normal.
CONCLUSION: The nasal cut ends can be found successfully by “directly under a microscope”, “guided by probing needle” and“pigtail curved probe”;the effect of silicone drainage tube used as lacrimal canaliculi bracket is satisfactory; most patients gained excellent recovery for both appearance and function after Z-plasty.
3.The expression of caspase-10 in differentiated thyroid carcinoma and association with its development and metastasis
Da-long, YIN ; Hai-yan, YANG ; Lian-xin, LIU ; Xi, CHEN ; Lan-tian, TIAN ; Shu-geng, ZHANG ; Hong-chi, JIANG
Chinese Journal of Endemiology 2009;28(5):493-496
Objective To investigate the expression of caspase-10 in differentiated thyroid carcinoma and association with its development and metastasis. Methods Thyroid samples from 37 patients in a period from January 2006 to December 2007, with differentiated thyroid carcinoma were retrospectively analyzed for caspase-10 by immunohistocbemistry(streptavidin-perosidase, S-P), compared to control group of 46 cases with nodtdar goiter. The relationship between the expression of caspase-10 and the clinical pathologic characteristics of thyroid carcinoma were also explored simultaneously. Results caspase-10 were observed as brown or yellow particles located in the cytoplasm or cell membrane of nodular goiter but there were no significant evidence for its positive expression in thyroid carcinoma, caspase-10 expression was markedly down-regulated in differentiated thyroid carcinoma(29.73%,11/37) compared with benign nodules(71.74%,33/46, χ2=14.528, P<0.01). The positive expression in 18 cases with lymph node metastasis(11.11%,2/18) was significantly lower than those in 19 patients without lymph node metastasis(47.37%,9/19; χ2=4.210, P<0.01). There was no significant correlation(P> 0.05) between the expression of caspase-10 and the clinical pathologic characteristics including male, age, TNM stage and pathologic type. Conclusion Down-regulation of caspase-10 may play a critical role in carcinogenesis and development of differentiated thyroid carcinoma.
4.Difference in effect between asthma-based mouse model and Stemona tuberosa extracts.
Xiao-Xi CHEN ; Xiao-Dan ZHANG ; Hong-Yan LI ; Tian-Zhu JIA ; Jing-Xian YANG
China Journal of Chinese Materia Medica 2013;38(23):4084-4087
In this study, OVA-induced asthma mice was taken as the model, and orally administered with different concentration of ethanol extracts of crude and processed Stemona tuberosa, in order to determine the cytokine level released from Th1 and Th2 in splenocytes. RT-PCR was carried out to determine the genetic expression of T-bet/GATA-3 in lung, and compare the differentiation between ethanol extracts of crude and processed S. tuberosa in therapeutic effect on asthma in mice. According to the results, compared with the crude samples, processed samples significantly increased the levels of inflammatory factor INF-gamma (P < 0.05) and decreased IL-5 (P < 0.05) in splenocytes. According to the RT-PCR results, the administration of processed samples could increase the ratio of T-bet/GATA-3 (P < 0.05). The experiment showed that ethanol extracts of both crude and processed S. tuberosa could treat asthma by regulating Th1/Th2 ratio, but processed samples showed more notable effect. This indicated that crude and processed S. tuberosa had significant pharmacological difference. Therefore, it was more rational to apply processed S. tuberosa in clinical treatment of asthma and chronic cough, which layed a foundation for further revealing the processing mechanism of S. tuberosa.
Administration, Oral
;
Animals
;
Asthma
;
drug therapy
;
immunology
;
metabolism
;
Disease Models, Animal
;
Drugs, Chinese Herbal
;
administration & dosage
;
pharmacology
;
therapeutic use
;
GATA3 Transcription Factor
;
metabolism
;
Gene Expression Regulation
;
drug effects
;
Mice
;
Mice, Inbred BALB C
;
Stemonaceae
;
chemistry
;
T-Box Domain Proteins
;
metabolism
;
Th1 Cells
;
drug effects
;
secretion
;
Th2 Cells
;
drug effects
;
secretion
5.Technical improvement in dealing with chronic atrophic gastritis samples.
Hong-xi MA ; Hai-feng WANG ; Zhuang TIAN ; Chang-yan XU
Chinese Journal of Pathology 2012;41(9):637-638
Adult
;
Aged
;
Aged, 80 and over
;
Female
;
Gastritis, Atrophic
;
diagnosis
;
pathology
;
Gastroscopy
;
methods
;
standards
;
Humans
;
Male
;
Middle Aged
;
Specimen Handling
;
methods
;
Tissue Embedding
;
methods
6.Applying the Canadian occupational performance measure in the rehabilitation of stroke patients
Yanling XI ; Ling ZHU ; Xiaoxue DEND ; Kahirman KURBANAM ; Huirong YAN ; Chong TIAN ; Baolan WANG
Chinese Journal of Physical Medicine and Rehabilitation 2012;(10):764-766
Objective To observe the different needs of Uighur and Han stroke patients for oceupational activities using the Canadian occupational performance measure (COPM).Methods The COPM was employed to evaluate 51 stroke patients in hospital before and after treatment.Thirty were from the Han ethnic group and 21 were Uighur.The first evaluation was performed at admission to confirm their occupational activity problems.Interventions were then planned using a patient-centered occupational therapy model.At discharge the second evaluation was performed to assess and compare the effects of treatment.Results In the first evaluation,both the Uighur and Han stroke patients had problems with self-care activities which were more prominent than those with productive and leisure activities.Older Uighur patients had special occupational activity needs resulltng from their religious practices.Compared witb the first evaluation,the total performance and satisfaction scores had improved significantly by the second evaluation for both the Han and Uighur patients,but their satisfaction scores were lower than their occupational activities performance scores.Conclusion Different nationalities may have different occupational activities needs.The COPM is easy to use and helpful in confirming occupational activity problems.Its use can contribute to the plan ning of primary goals for rehabilitation and treatment programs and help assess the effect of rebabilitation.
8.Academic origin of round magnetic needle and standardization operation.
Yan-Ting CHENG ; Tian-Sheng ZHANG ; Li-Qiang MENG ; Rui-Qi SHI ; Lai-Xi JI
Chinese Acupuncture & Moxibustion 2014;34(7):705-708
The origin and development of round magnetic needle was explored, and the structure of round magnetic needle was introduced in detail, including the handle, the body and the tip of the needle. The clinical opera tion of round magnetic needle were standardized from the aspects of the methods of holding needle, manipulation skill, tapping position, strength of manipulation, application scope and matters needing attention, which laid foundation for the popularization and application of round magnetic needle.
Acupuncture Therapy
;
history
;
instrumentation
;
methods
;
standards
;
China
;
History, Ancient
;
Humans
;
Medicine in Literature
;
Needles
;
history
;
standards
9.Tongue base surgery with front neck access and uvulopalatopharyngoplasty for treatment of severe obstructive sleep apnea-hypopnea syndrome.
Qing-Quan ZHANG ; Xi-Cheng SONG ; Tian-Zhen ZHANG ; Yan SUN ; Hua ZHANG
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2005;40(9):704-705
Adult
;
Aged
;
Female
;
Humans
;
Male
;
Middle Aged
;
Otorhinolaryngologic Surgical Procedures
;
methods
;
Sleep Apnea, Obstructive
;
surgery
;
Tongue
;
surgery
;
Uvula
;
surgery
10.Genetic characteristics of breakthrough varicella-zoster virus infection during the varicella outbreaks in Minhang District of Shanghai
Jia LU ; Yan DU ; Xi WANG ; Ye WANG ; Baofang JIN ; Kewen MEI ; Xia TIAN ; Liping ZHANG
Chinese Journal of Microbiology and Immunology 2016;36(4):271-276
Objective To analyze the genetic characteristics of breakthrough varicella-zoster virus infection during the varicella outbreaks in Minhang District of Shanghai in 2013-2014. Methods Samples of the varicella-zoster liquid were collected from patients with chickenpox in Minhang District in 2013-2014 and used for the extraction of genomic DNA. The open reading frame ( ORF) of 22 and 62 regions were se-quenced and further analyzed by using bioinformatics methods. Results A total of 24 samples were success-fully collected and sequenced, and all of them were wild strains. Among the 24 varicella-zoster virus strains, 23 strains were highly homologous to the parental strain ( P-Oka) and the vaccine strain ( V-Oka) , indica-ting that they belonged to J genotype. Only one strain, whose genotype was between M and E, was highly ho-mologous to the mosaic( M) CA123 strain ( M1 genotype) , indicating that it might belong to M1 genotype. Conclusion The epidemic strains of varicella-zoster virus in Minhang District were mainly J genotype. Lo-cal epidemic of M and other genotypes of varicella-zoster virus also existed. There were some gene variations in different strains of J genotype. These varicella-zoster virus strains of non-vaccine genotypes might be one of the reasons causing the breakthrough cases of chicken pox.