Objective To investigate the effect of Dougenguanshitong oral liquids (DGGST) on the treatment of esophageal carcinoma model rats. Methods Esophageal carcinoma rats model were made by Wistar rats that were treated with MANA 5 mg/kg (s.c. once weekly) for 20 weeks. Control group were given Ftorafur. The rats were sacrificed to examine esophageal carcinoma histopathology change under sight and microscope after treated by DGGST. Result The morbidity and canceration rate of tumour of all Chinese medicine treated groups and chemotherapy group were lower than the model group. The difference between each Chinese medicine treated group and chemotherapy group was remarkable (P

Objective To evaluate the influence of Bisoprolol on the cariac function and heart rate of in the cor pulmonale patients with heart failure. Methods 55 heart failure patients associated with cor pulmonale were randomly divided into two groups. The patients of treatment group(n=35) were orally given. The patients of control group(n=20) only received routine therapy. Bisoprolol except routing therapy. During the treatment the changes of cariac function and heart rate of all patients were observed, and before the Bisoprolol treatment and at 6th and 12th weeks after Bisoprolo treatment, the levels of creatinine, uricemia(UA), total cholesterol(TC), triglyceride(TG), high density lipoprotein cholesterol(HDL-C), and fasting plasma glucose were measured. Results In Bisoprolol treatment group the total effective rate was 94 3%, and was 75% in the control group(P0 05). Conclusion The ? 1-receptor blocker Bisoprolol was effective, and safe for treating the heart failure associated with cor pulmonale.

Objective To investigate the relationship between metabolic syndrome and related factors and recurrence of ischemic stroke.Methods 90 in-and out-patients with ischemic stroke in Jiangbei District Hospital of Traditional Chinese Medicine during May 2013 and May 2014 were enrolled.In 90 cases,4 patients with cerebral hemorrhage were excluded.Basic data of the 86 patients were investigated,which including gender,age,abdominal circumference,smoking,drinking,family history of stroke,diabetes,hypertension,hyperlipidemia,a history of atrial fibrillation,transient ischemic attacks,fasting blood glucose,triglyceride,cholesterol,uric acid,homocysteine,urinary protein-creatine ratio,carotid ultrasound examination.We investigated patients with or without recurrent stroke during one year of telephone visit and follow-up.Patients with recurrent stroke were investigated.Results During the one year follow-up,24 cases in the 86 patients with ischimic stroke were recurrent,the recurrence rate was 27.9 ％.2 cases in the recurrent patients died because of massive cerebral infarction,accounted for 8.3％ of the patients with recurrent stroke.According to Chi-square test,smoking,high fasting plasma blood glucose,hypertension,elevated low density lipoprotein cholesterol,high uric acid,high homocysteine and carotid atherosclerosis all had correlation with recurrent stroke(P＜0.05).In this logistic-regression model,smoking,high fasting plasma blood glucose,hypertension,elevated low density lipoprotein cholesterol,high uric acid,high homocysteine and carotid atherosclerosis were all predictors for recurrence of ischemic stroke.Conclusion Cntrolling the risk factors after the first stroke as a long term strategy has important clinical significance for secondary prevention of ischemic stroke.

Changes in the cytotoxicity of tetrandrine before and after liposome encapsulation on rat alveolar macrophages in vitro were ohserved. Results suggested that there was a siginificant differentiation on the adsorptive capacity to yeast, and the level in cytoplasmic free calcium and potassium, and the cytoskeletal control of macrophages at the concentration of 40?g/ml. Experiments showed that liposome encapsulation may attenuate cytotoxicity of tetrandrine.

Adult ; Humans ; Orthodontics, Corrective ; methods ; Periodontium

Biomedical Research ; Child, Preschool ; China ; Humans ; Pediatrics

Education, Medical, Continuing ; methods ; Evidence-Based Medicine ; Humans ; Pediatrics ; Periodicals as Topic ; Physicians ; Problem-Based Learning

Child ; Humans ; Immunologic Deficiency Syndromes

Child ; Child Welfare ; legislation & jurisprudence ; China ; Humans ; Law Enforcement ; Legislation as Topic ; Pediatrics ; legislation & jurisprudence ; Physician's Role

Child ; Genetic Association Studies ; Genetic Predisposition to Disease ; genetics ; Genotype ; Humans ; Mutation ; Pediatrics ; Phenotype ; Physicians ; Polymorphism, Single Nucleotide ; genetics