The paper summarized the current situation of diagnosis and treatment of pancreatic endocrine tumors (PETs)in China.In recent sixty years, we understand PETs more deeply, and have all kinds of imaging technique to localize the tumors.It makes more cases having been diagnosed.Operation is the most important and the first choice of treatment.The concept of minimal-invasion runs through the surgical procedure.Multi-model strategy is used in therapy for malignant PETs with liver metastasis.Basic research is focused in mechanism and early diagnosis and it helps the clinical practice.Specialization and co-operation are emphasized in the development of PETs diagnosis and treatment.

The theory of'preventing possible disease'in Traditional Chinese Medicine(TCM) is an important content of present theoretical and applied researches in TCM.After learning Daoxue and Chinese medicine,the author believes that ancient people give more attention to vitality than physique.Most of the diseases are caused by the injury of vitality,so the key to 'preventing possible disease'is not only conservation of the physique,but also conservation of the vitality.It is emphasized that the heart can communicate with natural pneuma,and the body can follow the qi transformation of nature when the human body is in the natural state.When one concentrates his spirit internally and keeps a sound mind,the genuine qi will come in the wake of it,and illness can be avoided.Researches on the theory of'preventing possible disease'must not ignore the apprehension and exploration of vitality.

From April 2011 to October 2013,68 patients scheduled for complex hepatobiliary and pancreatic surgery underwent full-thickness suturing of abdominal incision with subcutaneous negative pressure drainage.There was no such complications as wound dehiscence or sinus formation.Except for 2 cases of wound infection,primary healing was achieved.Two infected cases were followed up for 1 year and there was incisional hernia.The full-thickness suturing of abdominal incision plus subcutaneous negative pressure drainage could prevent postoperative wound infection and promote wound healing.And this simple and practical approach is worthy of wider clinical application.

As the newest anti-vascular endothelial grown factor (VEGF) drug,alfibercept binds to all forms of VEGF-A,VEGF-B, and PIGF.So far, intravitreal injection of alfibercept has already been used to treat certain opthalmological diseases, such as neovascular age-related macular degeneration, polypoidal choroidal vasculopathy, central retinal vascular occlusion, diabetic macular edema, corneal neovascular,and retinopathy of prematurity.In this article,we contrasted alfibercept to the other anti-VEGF drugs, conducted a review of the recent research progress of alfibercept in opthalmological diseases and introduced the questions which still need to be solved and the probably research direction of alfibercept in the future.

Antiinflammatio No. 6 (AI6) is an effective anti-infective drug composed of four traditional Chinese medicines, namely, Lonicera japonica Thunb, Taraxacum mongolican I-Iand-Mazz, Isatis tinctoria L. and Houttuynia cordata Thunb. It was demonstrated in our experiments that the drug was able to enhance the oxidative burst of rat peritoneal macrophages as shown by increased production of H_2O_2 and exaggerated reduction of nitroblue tetrazolium (NBT). It seems likely that by these means AI6 could promote the bactericidal function of macrophagcs. NBT rcduction of macrophages was examined both by spectrophotometric quantification and electromicroscopic observation.

Adult ; Humans ; Orthodontics, Corrective ; methods ; Periodontium

Colorectal cancer is one of the most commonly seen malignant tumors,and the metastatic colorectal cancer is of poor prognosis. The median overall survival for chemotherapy is only 1-1. 5 years. Recently,molecular targeted therapy targeting at vascular endothelial growth factor and epidermal growth factor receptor was used widely for metastatic colorectal cancer and becoming a hot spot of related researches. This article focused on the strategy and hypothesis of molecular targeted therapy for treatment of metastatic colorectal cancer.

Objective:Based on the level evaluation model of tuberculosis control established by analytic hierarchy process model, put forward the method of comprehensive evaluation of the quality of tuberculosis(TB) control and prevention work.Methods: The evaluation target of tuberculosis disease control and prevention was analyzed using analytic hierarchy process. At the same time, the weight of each evaluation index was established by the comparison of the pairwise comparison judgment matrix. And 3 TB control institutions in Beijing were evaluated.Results:Using this model, the comprehensive evaluation index of 3 TB control institutions was 65.6, 54.2 and 57.7 respectively.Conclusion: Analytic hierarchy process is a combination of qualitative and quantitative analysis. It is comprehensive, flexible and simple. At the same time, it is a good method for the evaluation of tuberculosis control and prevention in hospitals, and can be used as an effective tool for the management of tuberculosis control and prevention.

Objective: To observe clinical and serologic effects of self-made Chinese drug Liangxue Baidu Decoction Granules combined with azithromycin on early syphilis. Methods: 68 cases of early syphilis were randomly divided into two groups. The treatment group (u=43) were treated by Liangxue Baidu Decoction Granules combined with azithromycin and the control group (n=23) by simple azithromycin. Their therapeutic effects were compared. Results: There were significant differences between the two groups in the returning-negative rate of TRUST 1, 3, 6, 9 and 12 months after treatment (P

Objective To investigate the acoustic f eatures of voice in patients with abnormal lung function, evaluate the effect o f lung dysfunction on acoustics of voice,and observe the relationship between re spiration and phonation. Methods The voice signals of sustained vowel /a/ were mea sured by a micro-computer with Dr.speech science for windows software in 50 pati ents with abnormal lung function and 50 healthy adults. The acoustic parameters( F0,jitter,shimmer,intensity,NNE) were collected and analysed in lowest pitch,no rmal pitch and highest pitch.All patients were divided into two groups according to sex. Results In patients with abnormal lung function ,the pa rameters (shimmer, jitter, NNE,)were significantly increased or others(F0,inten sity) were significantly decreased in lowest pitch. Intensity decreased si gnificantly in highest pitch . There was a positive relationship between the de grees of lung dysfunction and the parameters of acoustics. Conclusion Abnormal lung function affected significantly on acoustics of voice in three different pitches; The changes of the parameters were related to the degrees of lung function.The results showed that respiratory activities play an important role in phonation.