1.Gastrointestinal neurosis treated by blood-letting.
Chinese Acupuncture & Moxibustion 2011;31(8):759-760
Adolescent
;
Adult
;
Aged
;
Bloodletting
;
Dizziness
;
therapy
;
Female
;
Gastrointestinal Diseases
;
therapy
;
Humans
;
Male
;
Middle Aged
;
Young Adult
2.Leukemic stem cell targeting therapy.
Chinese Journal of Oncology 2006;28(6):401-403
Animals
;
Antineoplastic Agents
;
pharmacology
;
therapeutic use
;
Chromones
;
pharmacology
;
therapeutic use
;
Hematopoietic Stem Cell Transplantation
;
methods
;
Humans
;
Leukemia
;
metabolism
;
pathology
;
therapy
;
Leupeptins
;
pharmacology
;
therapeutic use
;
Morpholines
;
pharmacology
;
therapeutic use
;
NF-kappa B
;
metabolism
;
Neoplastic Stem Cells
;
drug effects
;
Phosphatidylinositol 3-Kinases
;
antagonists & inhibitors
4.Reconstruction of maxillary defects by distraction osteogenesis of zygoma and free fibula composite flap.
Xue-gang NIU ; Xiao-xian HAN ; Yong HAO
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2007;42(9):703-704
Adult
;
Bone Transplantation
;
Fibula
;
transplantation
;
Humans
;
Male
;
Maxilla
;
surgery
;
Osteogenesis, Distraction
;
methods
;
Surgical Flaps
;
Zygoma
;
transplantation
5.Roles of G protein-coupled estrogen receptor in the male reproductive system.
Kai-hong CHEN ; Xian ZHANG ; Xue-wu JIANG
National Journal of Andrology 2016;22(2):175-179
The G protein-coupled estrogen receptor (GPER), also known as G protein-coupled receptor 30 (GPR30), was identified in the recent years as a functional membrane receptor different from the classical nuclear estrogen receptors. This receptor is widely expressed in the cortex, cerebellum, hippocampus, heart, lung, liver, skeletal muscle, and the urogenital system. It is responsible for the mediation of nongenomic effects associated with estrogen and its derivatives, participating in the physiological activities of the body. The present study reviews the molecular structure, subcellular localization, signaling pathways, distribution, and function of GPER in the male reproductive system.
Estrogens
;
metabolism
;
Genitalia, Male
;
metabolism
;
Humans
;
Male
;
Molecular Structure
;
Organ Specificity
;
Receptors, Estrogen
;
chemistry
;
physiology
;
Receptors, G-Protein-Coupled
;
chemistry
;
physiology
;
Reproduction
;
physiology
;
Signal Transduction
6.The application of enzyme-sensitive activatable cell-penetrating peptides to targeted delivery system.
Fan HE ; Li CAO ; Xue-Jing ZHANG ; Bai XIANG ; De-Ying CAO ; Xian-Rong QI
Acta Pharmaceutica Sinica 2015;50(2):141-147
Cell-penetrating peptides (CPPs) offer a non-selective and receptor-independent mode to promote cellular uptake. Although the non-specificity of CPP-mediated internalization allows this approach applicable to a wide range of tumor types potentially, their universality is a significant obstacle to their clinical utility for targeted delivery of cancer therapeutics and imaging agents. Accordingly, many reports have focused on selective switching of systemically delivered inert CPPs into their active form in lesions (tumor). In this review, our attention is mainly confined to such an enzyme-sensitive domain incorporated delivery system with activatable CPPs (ACPPs), which have displayed the exciting strength in balancing the CPPs' pros and cons, and potential in the treatment and diagnosis of some diseases.
Cell-Penetrating Peptides
;
chemistry
;
Drug Delivery Systems
;
Enzymes
;
chemistry
;
Humans
;
Neoplasms
;
drug therapy
8.Chromatographic fingerprint of Cnidium monnieri.
Xian YANG ; Shui-Ping YANG ; Xue ZHANG
Acta Pharmaceutica Sinica 2007;42(8):877-881
To establish the method of HPLC-fingerprint analysis for the quality control of Cnidium monnieri L. Cuss., and identify its active constituents by HPLC-MS, 35 batches of samples were analyzed on a Shimadzu C18 column with a gradient of acetonitrile and 0.1% aqueous aceticacid at a flow rate of 1.0 mL x min(-1) and detected at 245 nm and 322 nm. Furthermore, the typical samples were detected by HPLC-DAD-MS under negative ion mode. 35 batches of Cnidium monnieri L. Cuss. samples were classified into four types based on the results of similarity analysis. According to the comparison of the t(R), MS data and UV maximum absorbance (lambda(max)) values with the standards, 8, 7, 4 and 2 coumarins components were identified in four types of Cnidium monnieri L. Cuss. extracts, separately. The method is repeatable and reliable, and it is capable of effectively controlling the quality of Cnidium monnieri L.
Chromatography, High Pressure Liquid
;
methods
;
Cnidium
;
chemistry
;
Coumarins
;
analysis
;
Ecosystem
;
Plants, Medicinal
;
chemistry
;
Quality Control
;
Reproducibility of Results
;
Seeds
;
chemistry
;
Sensitivity and Specificity
;
Spectrometry, Mass, Electrospray Ionization
;
Spectrophotometry, Ultraviolet
10.Progress in studies on Mycoplasma pneumoniae-produced community-acquired respiratory distress syndrome toxin.
Xue-jing LI ; Shu-xian LI ; Zhi-min CHEN
Chinese Journal of Pediatrics 2013;51(7):555-557
Amino Acid Sequence
;
Animals
;
Bacterial Proteins
;
genetics
;
metabolism
;
Bacterial Toxins
;
genetics
;
metabolism
;
Base Sequence
;
Community-Acquired Infections
;
microbiology
;
Gene Expression Regulation, Bacterial
;
Humans
;
Lung
;
microbiology
;
pathology
;
Mycoplasma pneumoniae
;
Pneumonia, Mycoplasma
;
microbiology
;
Respiratory Distress Syndrome, Adult
;
microbiology