1.Gastrointestinal neurosis treated by blood-letting.
Chinese Acupuncture & Moxibustion 2011;31(8):759-760
Adolescent
;
Adult
;
Aged
;
Bloodletting
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Dizziness
;
therapy
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Female
;
Gastrointestinal Diseases
;
therapy
;
Humans
;
Male
;
Middle Aged
;
Young Adult
2.Attempt at and exploration on the practical teaching reform of dermatology staff room
Li XUE ; Xian JIANG ; Xi WANG
Chinese Journal of Medical Education Research 2002;0(01):-
To explore the value and attentive problems of the innovative practical teaching reform of dermatology staff room,the author constructed a new practical teaching system by carrying out advanced teaching methods,gradually establishing the on-line test system and setting up the evaluation and feedback system. The result showed that the innovative practical teaching reform of dermatology staff room had strong applicability and operability.
3.Leukemic stem cell targeting therapy.
Chinese Journal of Oncology 2006;28(6):401-403
Animals
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Antineoplastic Agents
;
pharmacology
;
therapeutic use
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Chromones
;
pharmacology
;
therapeutic use
;
Hematopoietic Stem Cell Transplantation
;
methods
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Humans
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Leukemia
;
metabolism
;
pathology
;
therapy
;
Leupeptins
;
pharmacology
;
therapeutic use
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Morpholines
;
pharmacology
;
therapeutic use
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NF-kappa B
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metabolism
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Neoplastic Stem Cells
;
drug effects
;
Phosphatidylinositol 3-Kinases
;
antagonists & inhibitors
5.Roles of G protein-coupled estrogen receptor in the male reproductive system.
Kai-hong CHEN ; Xian ZHANG ; Xue-wu JIANG
National Journal of Andrology 2016;22(2):175-179
The G protein-coupled estrogen receptor (GPER), also known as G protein-coupled receptor 30 (GPR30), was identified in the recent years as a functional membrane receptor different from the classical nuclear estrogen receptors. This receptor is widely expressed in the cortex, cerebellum, hippocampus, heart, lung, liver, skeletal muscle, and the urogenital system. It is responsible for the mediation of nongenomic effects associated with estrogen and its derivatives, participating in the physiological activities of the body. The present study reviews the molecular structure, subcellular localization, signaling pathways, distribution, and function of GPER in the male reproductive system.
Estrogens
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metabolism
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Genitalia, Male
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metabolism
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Humans
;
Male
;
Molecular Structure
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Organ Specificity
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Receptors, Estrogen
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chemistry
;
physiology
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Receptors, G-Protein-Coupled
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chemistry
;
physiology
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Reproduction
;
physiology
;
Signal Transduction
6.Development of methodology for auditing dosimetric parameters for photon and electron beams under non-reference conditions
Suming LUO ; Zhijian HE ; Kaibao LI ; Xian XUE
Chinese Journal of Radiological Medicine and Protection 2014;34(6):441-445
Objective To develop a methodology for auditing dosimetric parameters using TLD for photon and electron beams in non-reference conditions.Methods The correction experiments have been developed for non-linear dose response,PAAM holder,energy,fading and dispersion using TLD for 60Co γ-ray,high energy X-ray and electron beams.The measuring method was set up for absorbed dose estimation by TLDs in water.3 photon beams and 2 electron beams were selected for research purposes,and 5 photon beams and 4 electron beams for reliability research.Results The research results were evaluated for60Co source,6,10,15 and 18 MV photon beams in non-reference conditions at off-axis,with the relative deviation within-0.1%-7.2% at-off axis (IAEA's acceptable deviation:± 7.0%).The verification results were evaluated for 5 photon beams in non-reference conditions at on-axis,with the relative deviation are within 0.1%-7.0%.The verification results were evaluated for 4 electron beams in non-reference conditions,with the relative deviation within 0-4.7% (IAEA's acceptable deviation:±5.0%).Conclusions It is convenient and accurate to use TLD method for quality audits for clinic dosimetry parameters in radiotherapy.Two kinds of IAEA TLD holders are feasible for use in TLD audits.Absorbed doses for high energy electron beam were corrected using plane parallel chambers and verified using TLD,with good results obtained.
7.Development of the measurement method for MLC small field output factor in intensity modulated radiation therapy (IMRT)
Suming LUO ; Hao WU ; Zhijian HE ; Xian XUE ; Yanqiu DING
Chinese Journal of Radiological Medicine and Protection 2015;35(10):775-779
Objective To develop the methods for using 0.015 cc pinpoint chambers, 0.007 cc miniature chambers and diode detector to measure Multi-leaf collimator (MLC) small field in IMRT.Methods MAX4000 and Unidos electrometers were connected with different types of small chambers and diode detectors.MLC shaped fields of10 cm×10 cm, 6 cm×6 cm, 4 cm×4 cm, 3 cm×3 cm, 2 cm× 2 cm were defined at 100 cm SSD.The field sizes for the Varian accelerator were defined by the tertiary MLC, while the secondary jaws were kept at 10 cm × 10 cm field, with the monitor units of 250 MU.Each field was measured three times to obtain the average value.The readings of all small fields were normalized to 10 cm × 10 cm field values for comparison of measured and published output factors.Results The relative deviations of the MLC small field output factors from the published outputs are 1.0% , 1.7% , 1.5% and 2.4%, respectively, for Unidos electrometer connected with 0.015 cc pinpoint chamber;0.2%, 0.8%, 0.8% and 1.4%, respectively, for Unidos electrometer connected with 0.007 cc miniature chamber;and 0.1%, 0.5%, 0.5% and 0.9%, respectively, for MAX4000 electrometer connected with 0.007 cc miniature chamber.Conclusions The 0.015 cc chamber-measured MLC output factors for 3 cm × 3 cm and 2 cm × 2 cm fields are excellent.As required by IAEA, the relative deviations of the measured output factor from the published output factor are within ± 2% for 2 cm × 2 cm fields and ± 3% for larger fields.The results measured using 0.007 cc chamber are better than those measured using 0.015 cc chamber.The measured results using the diode detector, normalized to the 10 cm × 10 cm field, are consistent with the minimum requirements and excellent when being normalized to the 4 cm × 4 cm field.For dosimetric consideration, MLC small field output factor should be measured using small chamber and diode detector.The method is accurate and reliable, therefore, all measured output factors for MLC small fields should be input into radiation treatment plan system.
8.Reconstruction of maxillary defects by distraction osteogenesis of zygoma and free fibula composite flap.
Xue-gang NIU ; Xiao-xian HAN ; Yong HAO
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2007;42(9):703-704
Adult
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Bone Transplantation
;
Fibula
;
transplantation
;
Humans
;
Male
;
Maxilla
;
surgery
;
Osteogenesis, Distraction
;
methods
;
Surgical Flaps
;
Zygoma
;
transplantation
9.Role of protein tyrosine phosphatase SHP-2 in group I metabotropic glutamate receptors-induced allodynia
Man XUE ; Yunhui YANG ; Zhanwei SUO ; Xian YANG ; Xiaodong HU
Chinese Pharmacological Bulletin 2017;33(2):171-174
Aim To investigate whether the pain modi-fication by group I metabotropic glutamate receptors (mGluRs)required the involvement of Src homology-2 domain-containing phosphatase-2 (SHP-2 ).Methods Co-immunoprecipitation was performed to examine the possible interaction between SHP-2 and group I mGluRs in spinal cord dorsal horn of mice.By measur-ing the paw withdrawal thresholds,the effects of SHP-2 inhibitor NSC-87877 or its catalytically inactive SHP-2 (C459S ) mutant on allodynia induced by group I mGluRs agonist DHPG (50 nmol)were observed.Re-sults Anti-mGluR5 antibody was able to co-immuno-precipitate SHP-2 from spinal dorsal horn of mice, while no SHP-2 was precipitated by anti-mGluR1 anti-body.Inactivation of SHP-2 by NSC-87877 (6 nmol) or SHP-2 (C459S ) effectively attenuated allodynia caused by DHPG.Conclusion SHP-2 can physically interact with mGluR5.The activation of SHP-2 may be necessary for group I mGluRs to process the nocicep-tive information.
10.Optimization of taxol extraction from Taxus baccata L.
Xian YANG ; Shuiping YANG ; Xue ZHANG ; Jie TAN
Journal of Third Military Medical University 2003;0(19):-
Objective To optimize and establish the extractive technology of taxol from Taxus baccatal L.. Methods HPLC was applied to determine the content of taxol. The orthogonal test was adopted to examine the effects of the 4 factors consisting of ethanol concentration,ethanol volume,extractive times and extractive time. Results Ethanol concentration and ethanol volume were essential factors influencing the extraction of taxol. High concentration and amount of ethanol facilitated the extraction. Extractive times and extractive time were also important. By single-factorial effect,2 h and 2 times in each extraction of taxol were the best. Conclusion The optimum extractive condition is T9 (A3B3C2D1) and T8 (A3B2C1D3).