1.Improving comprehensive quality of gastrointestinal surgeons to cope with complicated medical environment.
Chinese Journal of Gastrointestinal Surgery 2012;15(1):8-9
The doctor-patient relationship has become increasingly tense. The requirement of the society for physicians, especially surgeons is higher. Apart from fine professional skills, surgeons must learn some other skills, such as communication, the ability of self-decompression, and the awareness of public relationship to deal with inculpation from the media and society. The medical record is more and more important nowadays, surgeons should pay enough attention to it. The public misunderstanding of the medical profession will surely harm both doctors and patients in the end.
Adaptation, Psychological
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Attitude of Health Personnel
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Communication
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Digestive System Surgical Procedures
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Humans
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Physician-Patient Relations
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Physicians
4.Functions and characteristics of calcium-sensing receptorsand effects of CaSR on characteristics of adult stem cells
Chinese Pharmacological Bulletin 2017;33(4):465-468
Calcium-sensing receptor(CaSR) is a widely distributed G-protein coupled receptor.The activated CaSR plays an important role in many kinds of signaling pathway regulation, such as Ca2+ signaling pathway.It not only maintains the body calcium balance, but also is involved in the regulation of a variety of cell secretion, proliferation, apoptosis, and ion channel opening processes.CaSR expression is involved in stem cell migration, adhesion and homing in hematopoietic stem cells and mesenchymal stem cells.The activated CaSR also regulated the function of itself and characteristics in stem cells through a variety of cell signaling pathways.We introduce the functions and characteristics of CaSR, the relationship between CaSR and disease, and review the effects of the biological characteristics on hematopoietic stem cells and mesenchymal stem cells.
5.Effects of Pine Pollen on Expression of p16 and p21 in Human Embryonic Lung Diploid Fibroblasts
Journal of Zhejiang Chinese Medical University 2007;0(01):-
[Objective] To observe the effects of pine pollen on the changes of p16INK4a and p21WAF1 in 2BS cells.[Method]The 2BS cells were cultured from 28 population doubling(PD)and divided equally into the young control group,old control group,middle-dose pine pollen group(120mg/dl)and high-dose pine pollen group(240mg/dl)randomly.Regulate the phases of cell cycle by flow cytometry,and then the expression of p16INK4a,p21WAF1 mRNA were determined by semi-quantitative RT-PCR.[Result]The amount of cells in G1 phase was depressed in middle-dose pine pollen group(72.73%?1.76%)and high-dose pine pollen group(64.15%?0.87%)than in old control group(81.33%?3.43%)noticeablely(P
6.The clinical analysis of 109 cases of vulvar squamous cell carcinoma
Cancer Research and Clinic 2014;26(4):241-242,249
Objective To analyze the clinical data of vulvar squamous cell carcinoma and discuss the related risk factors.Methods The clinical data obtained from 109 cases of vulvar squamous cell carcinoma were analyzed retrospectively.Results The most common ages of onset were 50-69 years.The course of canceration was usually 6-12 months,and most lesions occurred on the labia majora.The sizes of tumour were around 2-4 cm,and more than 90 % of lesions were well-differentiated squamous cell carcinomas.According to 2009 FIGO new staging of vulva cancer,more patients were reclassified as stage Ⅰ B,while patients with stage Ⅱ and Ⅲ became less.99 out of 109 patients also had nonneoplastic epithelial disorders of vulva.The lesions mostly affected the labia majora and the labia minora,and 60 % of them were pathologically diagnosed as lichen sclerosus.Patients with nonneoplastic epithelial disorders of vulva usually developed into vulvar carcinoma within 10-15 years.Conclusion The incidence of vulvar squamous cell carcinoma is closely related with vulvar nonneoplastic epithelial disorders of the vulva.As the chronic nonneoplastic epithelial disorders of vulva increase the risk of vulvar cancer,periodic follow-up will help its early detection.
7. Expression of PPARγ in rat brain after status epileticus
Academic Journal of Second Military Medical University 2010;31(1):42-45
Objective: To observe the expression of PPARγ in rat brain after status epilepticus. Methods: Male Sprague-Dawley rats were randomly divided into a control group and a status epilepticus group(n=10). Lithium-pilocarpine model was used to prepare epileptic model. Immunohistochemical method and Western blotting analysis were used to examine the changes of PPARγ distribution and expression in rat brain in the two groups. Results: Immunohistochemical staining showed that the expression of PPARγ was weak in the brain of normal rats, and the expression was mainly on the neurons. The expression was strong in astrocytes after status epilepticus, and the expression was also noticed on cells with neuron shape. Western blotting analysis showed that the expression of PPARγ was greatly increased after status epilepticus. Conclusion: The expression of PPARγ is increased on astrocyte after status epilepticus in rats, which may have neuroprotective effect. This finding cast new lights on neuroprotective treatment for epilepsy.
8.Warm Needling Moxibustion at Zhongji (CV 3) and Zusanli (ST 36) for Urinary Retention after Gynecological Surgery
Journal of Acupuncture and Tuina Science 2014;(6):379-382
Objective:To observe the clinical effect of warm needling moxibustion at Zhongji (CV 3) and Zusanli (ST 36) in treatment of urinary retention after gynecological surgery. <br> Methods: Forty patients with urinary retention after gynecological surgery were randomly divided into two groups by the randomized method, 20 cases in each group. Patients in the treatment group were treated by warm needling moxibustion at Zhongji (CV 3) and Zusanli (ST 36). Patients in the control group were treated by inductive urination. The therapeutic effects of the two groups were observed after one course of treatment. <br> Results:The total effective rate was 95.0%in the treatment group and 70.0% in the control group. The difference in the total effective rate between the two groups was statistically significant (P<0.05). <br> Conclusion: Warm needling moxibustion at Zhongji (CV 3) and Zusanli (ST 36) is more effective than inductive urination in treating urinary retention after gynecological surgery.
9.Clinical effect of Qiuxieling associate with Licorzinc in treatment of infantile rotavirus enteritis
Chongqing Medicine 2015;(23):3229-3230
Objective To explore the effects of Qiuxieling associate with Licorzinc therapy on infantile rotavirus enteritis. Methods Infants with rotavirus enteritis were divided into 4 groups (symptomatic and supportive treatment group,Licorzinc group,Qiuxieling group,and Qiuxieling combined with Licorzinc group).The curative effect was analyzed.Results The total ef-fective rates of symptomatic and supportive treatment group,Licorzinc group,Qiuxieling group,and Qiuxieling combined with Licorzinc group were 77.5%,82.5%,85.0% and 92.5%.The average disease courses of symptomatic and supportive treatment group,Licorzinc group,Qiuxieling group,and Qiuxieling combined with Licorzinc group were (6.44 ± 0.79 ),(5.82 ± 0.55 ), (5.66±0.50)and (4.78 ±0.50)days.The curative effects were significantly higher in Qiuxieling combined with Licorzinc group compared to symptomatic and supportive treatment group,Licorzinc group and Qiuxieling group (P <0.05).Conclusion Qiuxiel-ing and Licorzinc were significantly effective in the treatment of infantile rotavirus diarrhea,and can short the disease course.
10.Research of correlative factors between the ultrasonography of trauma-caused deep venous free-floating ;thrombus of lower limbs and the prognosis
Chinese Journal of Ultrasonography 2015;(6):496-499
Objective To analyze the color Doppler ultrasonography of trauma-caused deep venous free-floating thrombus(FFT)of lower limbs,discuss the relations between sonography and the prognosis. Methods Clinical data and color Doppler ultrasound examination results of 130 cases with trauma-caused deep venous FFT of lower limbs were retrospectively analysed.Univariate analysis was conducted to identify the statistically significant factors of patients' prognosis,non-conditional logistic regression analysis was performed to analyse the independent prognostic factors of FFT.Results The non-conditional logistic regression analysis showed that the position of FFT,thrombosis edge definition,floating degree and the volume of detouring blood around the thrombus were independent factors of patients'prognosis(P <0.05). The FFT prognosis of iliofemoral vein was more likely to be fixed than the FFT prognosis of popliteal vein. The FFT prognosis with blurring edges was more likely to be fixed.The more obvious the floating degree of FFT,the higher chance that the FFT prognosis is recanalized.More detouring blood flow around FFT indicated more possibilities that the prognosis could be recanalized.Conclusions The color Doppler ultrasound is able to evaluate the relations between the deep venous free-floating thrombus of lower limbs and prognosis of the patients,which is beneficial for early detection and early treatment,as well as reducing mortality and disability resulted from deep venous thrombus during the orthopaedic perioperative period.