1.ApoB gene genetic polymorphism of Han nationality and Mongolian nationality in midwest area of Inner Mongolia.
Yang LIU ; Jun JI ; Wu-Ren-Tu-Ya BAO ; Fan YANG ; Hai-Rong WU
Journal of Forensic Medicine 2014;30(1):52-54
OBJECTIVE:
To study ApoB gene genetic polymorphism of Han nationality and Mongolian nationality in midwest area of Inner Mongolia.
METHODS:
Some unrelated individuals of Han nationality and Mongolian nationality in midwest area of Inner Mongolia were selected. Polymerase chain reaction-restriction fragment length polymorphism technology was used to check the presence of Xba I (X+) and EcoR I (E-) sites of rare alleles. The genotype frequency, allelic frequency and population genetics parameters were calculated.
RESULTS:
The frequencies of Xba I (X+) and EcoR I (E-) rare alleles were 2% and 4.6% in Han population. There was no Xba I (X+) or EcoR I (E-) rare alleles found in Mongolian nationality.
CONCLUSION
The allelic frequencies of ApoB gene Xba I and EcoR I sites are very different in different races. These sites may be used in identification of ethnicity.
Alleles
;
Apolipoprotein B-100/genetics*
;
Asian People/genetics*
;
China
;
Ethnicity
;
Gene Frequency
;
Genotype
;
Humans
;
Mongolia
;
Polymerase Chain Reaction
;
Polymorphism, Genetic
;
Polymorphism, Restriction Fragment Length