1.Acupuncture plus Chinese Medicinal Fumigation and Washing for Edema of the Stroke-affected Limb
Journal of Acupuncture and Tuina Science 2014;(5):278-281
Objective: To evaluate the therapeutic efficacy of acupuncture plus Chinese medicinal fumigation and washing in treating edema of the affected limb in post-stroke hemiplegia. <br> Methods: Two hundred patients with edema of the stroke-affected limb from our hospital were randomized into two groups according to their visiting sequence. In the observation group, 100 subjects were intervened by acupuncture plus Chinese medicinal fumigation and washing in addition to oral administration of diuretics, while the other 100 subjects in the control group were only given diuretics. The therapeutic efficacy was evaluated after successive 2-week treatments. <br> Results: The total effective rate was 90.0% in the observation group, significantly higher than 66.0% in the control group, indicating that there was a significant difference in comparing the overall therapeutic effect (P<0.01). <br> Conclusion: Acupuncture plus Chinese medicinal fumigation and washing in addition to oral administration of diuretics is effective in treating edema of the affected limb in post-stroke hemiplegia.
2.Expression of CD40/CD40L in lung tissue of rabbits with hemorrhagic shock
Journal of Chongqing Medical University 1986;0(02):-
Objective:To investigate the expression and the effects of CD40/CD40L in lung tissue of rabbits with hemorrhagic shock.Methods:18 healthy rabbits were randomly divided into control group(group A),hemorrhagic shock 1 hour group(group B) and hemorrhagic shock 2 hours group(group C),with 6 rabbits in each group.Except the rabbits in the control group,rest rabbits were made into hemorrhagic shock models with lung injury according to Wiggers modified method.TNF-?、IL-10 in plasma were measured by ELISA.Expressions of CD40 and CD40L in lung tissue were measured by immunohistohemistry.Water quantity and pathological change in the lung were observed.Results:The lung of group B and C displayed obvious injury,water quantity increased(P
3.Hospital Disinfection Quality Surveillance Analysis:10 Year Results and Impact Factors
Chinese Journal of Nosocomiology 2006;0(09):-
OBJECTIVE To learn about the state of disinfecting quality and its impact factors of our hospital in recent 10 years.METHODS According to GB15982-1995 and GB15981-1995 the sampling and surveillance were carried out to the objects concerned for disinfecting in the hospital.RESULTS It showed ascent trend in its entirety for the qualified rate of sample surveillance(70.53-96.34%).The qualified rates of applying disinfecting liquid,medical treatment necessities and pressure steam sterilizer were also higher in the surveillance each year.CONCLUSIONS The lows and regulations correlated with disinfection and operating technological specification have become more and more perfect and flawless,supervision and management also have been intervened and strengthened,and the level of the consciousness and knowledge of disinfection among the staff have had elevation,all these have elevated the disinfection job of the hospital in quality.
4.Application researches of mesenchymal stem cells combined with statins in diabetic retinopathy
Chinese Journal of Experimental Ophthalmology 2017;35(7):660-663
Diabetic retinopathy (DR) is a common complication of eye in diabetics and is one of the major causes of blindness in adults.The current treatments of DR include surgery and laser therapy,but this does not fundamentally cure DR.Recent studies have found that mesenchymal stem cells (MSCs) for cell therapy to DR have a wide range of applications.MSCs have regenerative potential and play a role in the repairment of the retina,but the survival and homing ability of MSCs are poor after transplantation,which reduces the therapeutic efficiency of MSCs.Statins have a variety of beneficial effects independent of lipid regulation,which can promote the proliferation of MSCs and inhibit the apoptosis of MSCs.This paper reviewed the application and mechanism of MSCs combined with statins in the treatment of DR.
5.Interpretation of“European Evidence Based Consensus on Surgery for Ulcerative Colitis”
Chinese Journal of Gastroenterology 2016;21(12):705-707
The goal of the consensus initiated by the European Crohn’s and Colitis organisation(ECCO)was to establish the European consensus guidelines for surgical treatment of ulcerative colitis. The consensus covered four parts:the preoperative phase,intraoperative phase,postoperative phase and special situations. This consensus guideline was published in“Journal of Crohn’s and Colitis”and posted on the websites of ECCo in 2015. Interpretation of main points of this consensus was presented in this paper.
6.The Effects of P27~(KIP-1) on Proliferation of Airway Smooth Muscle Cells in Asthmatic Rats.
Journal of Medical Research 2006;0(01):-
Objective To investigate the effects of P27Kip-1 on proliferation of airway smooth musde and airway remodeling in asthmatic rats.Methodes 30 healthy,male SD rats were randomly and equally divided into three groups :control group(C),asthmatic 4 weeks group(A1),asthmatic 6 weeks group(A2).A rat asthma model was developed by the sensitized with ovalbumin and Al(OH)3,and repeatedly exposed to aerosolized ovalbumin.After the last challenge,The animals were evaluated for AHR,the airway wall thickness(Wat /Pbm)and the bronchial smooth muscle thickness(Wam/Pbm)were measured by image analysis system.The expression of P27Kip-1 and PCNA was determined by immunohis-tochemical staining.Results(1).The expression of P27Kip-1 protein in two asthmatic groups was significantly lower than that of the control group,respectively(P
7.Progression of brain tumor stem cell markers
Journal of International Oncology 2014;41(12):899-901
Brain tumor stem cells (BTSCs) play a key role in tumorigenesis and tumor development.There are a group of special markers in the surface of brain tumor stem cells,which can sorts stem cells,precursor cells and cancer stem cells.In recent years,the studies of CD133,Nestin,high-mobility group A1,A2B5 have made some breakthroughs.
8.Effect of spironolactone combined with valsartan on renal function in patients with early diabetic nephropathy
Chinese Journal of Biochemical Pharmaceutics 2015;(12):89-91
Objective To investigate the effect of spironolactone combined with valsartan on renal function in patients with early diabetic nephropathy.Methods 158 early diabetic nephropathy patients from May 2014 to June 2015 in department of endocrinology of Nanxun People’s Hospital of Huzhou were selected and divided into control group (79 cases) and experimental group (79 cases).The control group were treated by valsartan and the experimental group were treated with spironolactone on the basis of control group.The changes of renal function, potassium ion and blood rheology were observed and compared after treatment.Results Compared with control group post-treatment, the systolic pressure and diastolic pressure levels were lower, plasma urinary albumin excretion rates (UAER) level was lower (P <0.05), albumin (Alb), serum creatinine (Scr), blood urea nitrogen ( BUN) , creatinine clearance ( Ccr) and K +levels had no significant differences, whole blood specific viscosity, plasma specific viscosity and whole blood specific reduced viscosity were lower ( P <0.05 ) in experimental group.Conclusion Spironolactone combined with valsartan could effectively improve clinical efficacy of patients with early diabetic nephropathy , improve the renal function of patients, recover ion disorder and reduce blood viscosity.
9.Clinical analysis of HPV infection in cervical adenocarcinoma and its relationship with age of onset
Chinese Journal of Clinical and Experimental Pathology 2015;(5):514-517
Purpose To discuss the relationship between age of onset and the HPV types infection in cervical adenocarcinoma. Meth-ods This study included 120 specimens of cervical adenocarcinoma in Jiangxi Maternal and Child Health Hospital. The specimen blocks were sliced by sandwich method. DNA was amplified by SPF10-PCR method. DNA genotyping was used with LiPA method. All biopsy specimens had pathologic diagnosis. The HPV infection of cervical adenocarcinoma specimens was analyzed. Results 120 ade-nocarcinoma cases were included in this study. HPV positive rate was 77. 5% (93/120). HPV 18 was the most prevalent type, which took up 43. 01% (40/93) of the total HPV positive cases, as same as HPV 16, which took up 43. 01%(40/93) of the total HPV pos-itive cases. The average ages of HPV 16 and HPV 18 were 43. 41 and 41. 06 years old respectively, other HPV types were 46. 85 years old, which showed statistically difference (F=3. 58, P=0. 032). Conclusion HPV 18 and HPV 16 are two most prevalent HPV types in cervical adenocarcinoma. The cases of HPV 18 infection are younger than other HPV-types infection.
10.Analysis of factors in outcomes of infants with pulmonary hemorrhage
Journal of Clinical Pediatrics 2014;(9):812-815
Objective To investigate the risk factors in the outcome of neonatal pulmonary hemorrhage. Methods A total of 69 cases of neonatal pulmonary hemorrhage from January 2005 to December 2011 were studied. They were divided into 2 groups according to clinical outcome (death or alive). The data of the two groups were compared using single factor analysis. The risk factors were analyzed using multi-factor analysis. Results The death of neonates with pulmonary hemorrhage was correlated with aspiration pneumonia, coagulation abnormalities, DIC, heart failure and MPV. Multi-factor analysis showed that DIC (OR=6.90, 95%CI:1.514-31.419), heart failure (OR=9.62, 95%CI:1.710-54.150) and MPV<11 prior to pulmonary hemorrhage (OR=7.01, 95%CI:1.475-33.312) were the independent risk factors of neonatal pulmonary hemorrhage. Conclusions For the neonatal pulmonary hemorrhage with DIC, heart failure and low MPV, active intervention should be implemented.