2.A Case of Rhabdoid Meningioma.
Jung Ho HAN ; Ho Jun SEOL ; Dong Gyu KIM ; Hee Won JUNG
Journal of Korean Neurosurgical Society 2006;39(2):144-147
Rhabdoid meningioma is an uncommon meningioma variant, which was initially described in 1998 by Perry et al.. It is classified as a variant corresponding to grade III in the recent World Health Organization(WHO) classification of tumors of the nervous system, because of its unique histopathological features and its highly aggressive clinical course. To date there were still a lot of arguments about their developmental patterns and the treatment strategy especially for rhabdoid meningiomas lacking other histological features of malignancy. Although the exact causes of rhabdoid transformation of a benign meningioma are unknown, malignant transformation long duration after surgical resection under an underlying predilection for malignancy is suggested in our case. And we suggest that any histological rhabdoid features in recurrent meningiomas or even in primary cases seem to indicate the malignant clinical course and the need for aggressive treatments, because transformation from a benign or atypical one to a malignant one seems to occur at last.
Classification
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Meningioma*
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Nervous System Neoplasms
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World Health
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World Health Organization
3.Comparison of the Naranjo and WHO-Uppsala Monitoring Centre criteria for causality assessment of adverse drug reactions.
Myoung Kyun SON ; Yong Won LEE ; Han Young JUNG ; Seung Woo YI ; Kwang Hoon LEE ; Seung Up KIM ; Jae Heon JEONG ; Jae Jun PARK ; Jung Won PARK ; Chein Soo HONG
Korean Journal of Medicine 2008;74(2):181-187
BACKGROUND/AIMS: Several criteria have been proposed to increase the objectivity, reliability and validity of causality assessment of adverse drug reactions (ADR). We compared the Naranjo probability scale and the World Health Organization-Uppsala Monitoring Centre (WHO-UMC) causality categories to evaluate the validity and clinical usefulness of these criteria. METHODS: We evaluated 100 ADR cases with the Naranjo probability scale and the WHO-UMC causality categories. The Spearman rank coefficient was used to determine the correlation of these criteria. The evaluation of the ADR was categorized into four groups for the Naranjo system: definite, probable, possible, and doubtful, and six groups for the WHO UMC: certain, probable, possible, unlikely, conditional/unclassified, and unassessable. RESULTS: The criteria used form these two systems showed some differences when compared with the same ADR cases. The Spearman rank coefficient was 0.519 (p<0.001) and the agreement was 55% between the Naranjo probability scale and the WHO-UMC causality categories. The Naranjo probability scale includes measurements for drug concentration, objective evidence of ADR, ADR to previous exposures, responses to placebo, and the dose adjustment of drugs. However, few cases were evaluated for all of these measures. CONCLUSIONS: The Naranjo probability scale may be helpful for assessing unexpected ADRs and useful for evaluators with little experience. However, some of the items are not utilized and there are discrepancies when compared with the WHO-UMC causality criteria.
Drug Toxicity
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Reproducibility of Results
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World Health
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World Health Organization
4.Mid - evaluation activities of the primary school-base helminthiasis control project supported by Who (in 2002 - 2003)
Journal of Malaria and parasite diseases Control 2003;0(1):82-88
The primary school-based helminthiasis control project was carried out in 767 communes (39 districts of 11 provinces). It is a combinate of IEC activities and periodical deworming every 6 months with mebendazole 500mg. 1,217,754 school children times (in 1,146 primary schools) have been drug administrated, coverage 97.2% - 100%. Side effects were not high 0.03% - 0.29%. Stool examinations have shown that the prevalence of infection is 98.4% - 78.8% and 19.2% respectively in the North, Center and the South. The intensity of Ascaris, Trichuris and hookworm infection in almost of schools is not rather high. The KAP surveys have shown that the majority of school children and their parents have knowledges of the reasons and the complications of helminthiasis 62.3% - 80.5% and 99.0%. However, percentage of people using nightsoil as fertilizer is 10.3%
Helminthiasis
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World Health Organization
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Schools
5.Degradation, half-life and residual effects of pyrethroid impregnated nets on an.dirus
Journal of Malaria and parasite diseases Control 2004;0(3):59-66
This study was performed at Hanoi University of Natural Sciences and National Institute of Malaria and Parasitology from April 2001 to May 2002. Biological trials on laboratory strains of An. dirus were carried out according to WHO/VCB/81.806; WHO/CDS/CPC/MAL/98.12 and WHO/VCB/89.981. Analyses were conducted by the method of fluid-fluid extraction with the solvent system of n-hexan. Fendona 10SC,Icon 2,5CS,K-othrin ISC, Imperator 50EC .soaked mosquito bednet had manifested insecticide effect. Their effect of killing An.dirus was maintained for 5 -6 months. The procedure of analysis of pyrethroide compounds in use for soaking mosquito bednet was established and the half live of 125-188 day long period for each compound was determined
Pyrethrins
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metabolism
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world health organization
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6.Pay attention to the updates of 5th edition WHO classification of haematolymphoid tumours.
Chinese Journal of Pathology 2024;53(1):3-5
Two review articles summarizing the fifth edition of the World Health Organization (WHO) classification of haematolymphoid tumours were officially published on Leukemia journal in 2022. This article briefly summarizes some important advances and changes in the fifth edition of WHO classification of haematolymphoid tumours, and describes how to apply the classification dialectically and reasonably in the daily practice of pathologists, so as to accurately guide clinical treatments.
Humans
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Neoplasms
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World Health Organization
7.Examples of Holistic Good Practices in Promoting and Protecting Mental Health in the Workplace: Current and Future Challenges.
Kelly C SIVRIS ; Stavroula LEKA
Safety and Health at Work 2015;6(4):295-304
BACKGROUND: While attention has been paid to physical risks in the work environment and the promotion of individual employee health, mental health protection and promotion have received much less focus. Psychosocial risk management has not yet been fully incorporated in such efforts. This paper presents good practices in promoting mental health in the workplace in line with World Health Organization (WHO) guidance by identifying barriers, opportunities, and the way forward in this area. METHODS: Semistructured interviews were conducted with 17 experts who were selected on the basis of their knowledge and expertise in relation to good practice identified tools. Interviewees were asked to evaluate the approaches on the basis of the WHO model for healthy workplaces. RESULTS: The examples of good practice for Workplace Mental Health Promotion (WMHP) are in line with the principles and the five keys of the WHO model. They support the third objective of the WHO comprehensive mental health action plan 2013e2020 for multisectoral implementation of WMHP strategies. Examples of good practice include the engagement of all stakeholders and representatives, science-driven practice, dissemination of good practice, continual improvement, and evaluation. Actions to inform policies/legislation, promote education on psychosocial risks, and provide better evidence were suggested for higher WMHP success. CONCLUSION: The study identified commonalities in good practice approaches in different countries and stressed the importance of a strong policy and enforcement framework as well as organizational responsibility for WMHP. For progress to be achieved in this area, a holistic and multidisciplinary approach was unanimously suggested as a way to successful implementation.
Education
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Mental Health*
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Occupational Health
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Risk Management
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World Health Organization
8.Healthful living for all by year 2000 through the health education approach.
Yonsei Medical Journal 1990;31(3):193-196
No abstract available.
Goals
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*Health Education
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Health Promotion
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Human
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World Health Organization
10.Analysis of Factors Affecting the Need for Health Education Programs in Middle-aged Women.
Korean Journal of Health Promotion 2015;15(2):63-74
BACKGROUND: This study aimed to analyze the factors affecting health education program needs as defined by the World Health Organization (WHO) for promoting health in middle-aged women. METHODS: Study subjects included 203 middle-aged women ranging in ages between 40 and 59 years, living in S-city. Data were collected from September 10 to 24, 2011. Descriptive statistics, independent t-test, and one-way ANOVA were used to analyze general characteristics and the need for health education programs related to the general characteristics. Hierarchical multiple regression was used to access the factors influencing the need for health education programs. All data were analyzed by SPSS/WIN 17.0 program. RESULTS: The average score of the health promotion behaviors was 3.46 (+/-0.74). The average score of the need for health education programs (including physical, psychological, and social health education programs) was 3.88 (+/-0.13); and this was affected by age (psychological health education programs beta=-0.21), self-actualization (physical, psychological, social health education programs beta=0.28, beta=0.30, beta=0.30), health responsibility (social health education programs beta=0.21), interpersonal support (physical health education programs beta=0.18), and stress management (social health education programs beta=0.18). CONCLUSIONS: Based on the study results, health education for middle-aged women should be impacted less by monthly income and educational background, and should have more specialized, accessible contents considering not only programs that middle-aged women prefer but also the factors influencing the needs of health education.
Female
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Health Education*
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Health Promotion
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Humans
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World Health Organization