1.Outbreak associated with Rotavirus G11,P25 in Korea in 2018
Su-Jin CHAE ; Sunyoung JUNG ; Seung-Rye CHO ; Wooyoung CHOI ; Deog-Yong LEE
Infection and Chemotherapy 2020;52(4):616-620
We here report the first outbreak caused by rotavirus G11,P[25] in Korea in 2018, representing a case of re-assortment with pig-derived rotavirus. The genotype constellation was identical to the virus identified in Korea in 2012 as G11-P[25] -I12-R1-C1-M1-A1-N1-T1-E1-H1. The infection source was not known exactly but it must be considered infection from swine.
2.Sudden Death Due to Undiagnosed Ludwig’s Angina: An Autopsy Case Report
Wooyoung JANG ; Tae Mo KANG ; So Youn IM ; Mowa KANG ; Kwang Soo KO ; Jinhyuk CHOI
Korean Journal of Legal Medicine 2023;47(1):26-30
Ludwig’s angina is a rapidly progressive and gangrenous cellulitis in the submandibular, sublingual spaces, and neck. It is characterized by an elevated tongue and laryngeal edema, resulting in airway compromise and, rarely, in sudden death. The most common cause is an odontogenic infection of a molar tooth. Infection can spread to the superior mediastinum and buccal area through anatomical structures. Herein, we report the sudden death of a 45-year-old male who was not diagnosed with Ludwig’s angina. He died in the emergency room 20 minutes after loss of consciousness. Intubation was impossible owing to severe laryngeal edema. The C-reactive protein level was 33.81 mg/dL. On autopsy, a diffuse light green abscess of the submandibular space was detected, along with severe edema of the epiglottis, aryepiglottic fold, and vocal cords. Subsequently, we confirmed that the airway obstruction was caused by Ludwig’s angina based on a literature review. In conclusion, this report emphasizes the need to identify the infection source and perform a detailed dissection according to the anatomical structure in the autopsy procedure for Ludwig’s angina.
3.Outbreak associated with Rotavirus G11,P25 in Korea in 2018
Su-Jin CHAE ; Sunyoung JUNG ; Seung-Rye CHO ; Wooyoung CHOI ; Deog-Yong LEE
Infection and Chemotherapy 2020;52(4):616-620
We here report the first outbreak caused by rotavirus G11,P[25] in Korea in 2018, representing a case of re-assortment with pig-derived rotavirus. The genotype constellation was identical to the virus identified in Korea in 2012 as G11-P[25] -I12-R1-C1-M1-A1-N1-T1-E1-H1. The infection source was not known exactly but it must be considered infection from swine.
4.A Spontaneous Coronary Artery Dissection Autopsy in a 64-Year-Old Male
Sang Won LEE ; Wooyoung JANG ; Tae Mo KANG ; So Youn IM ; Kyungmin LEE ; Kwang Soo KO ; Jinhyuk CHOI
Korean Journal of Legal Medicine 2025;49(2):51-55
Spontaneous coronary artery dissection (SCAD) is a condition in which an intramural hematoma within the coronary artery leads to acute coronary syndrome without atherosclerosis, trauma, or iatrogenic causes. It predominantly affects middle-aged women and is associated with several predisposing conditions, including fibromuscular dysplasia, systemic inflammatory disorders, connective tissue diseases, and coronary artery spasms. We report the case of a 64-year-old male with a history of hypertension who died of SCAD. His death occurred suddenly and without preceding trauma while the decedent was working overtime at a construction site. On gross examination, a thrombus-like material was identified in a branch of the left anterior descending artery and was initially presumed to be a postmortem clot. However, microscopic examination revealed an intramural hemorrhage, medial dissection, and formation of a false lumen within the coronary artery. This case report highlights the importance of a thorough histopathological examination of the coronary arteries during autopsy, even in the absence of atherosclerosis.
5.Pilot Trial: Impact of a Virtual Reality Stress Reduction Program on Healthcare and Information Technology Professionals During the COVID-19 Pandemic
Daeho KWON ; Wooyoung IM ; Yunsoo KIM ; Jaesung YOO ; Huisu JEON ; Heeyong CHOI ; Hyeyun KIM
Psychiatry Investigation 2025;22(4):451-461
Objective:
This study evaluated the effectiveness of a virtual reality (VR) based stress reduction program tailored for healthcare and information technology (IT) professionals during the coronavirus disease-2019 pandemic.
Methods:
The 2-week program, based on forest healing principles, was designed to alleviate occupational stress and improve sleep quality. Participants (n=54; 46 healthcare, 8 IT professionals) underwent pre- and post-intervention assessments using validated psychological scales and physiological measurements.
Results:
Results showed significant reductions in stress (Perceived Stress Scale [PSS], p=0.001) and anxiety (Hospital Anxiety and Depression Scale [HADS] anxiety, p=0.002) across all participants. Healthcare professionals demonstrated significant decreases in depression (Patient Health Questionnaire-9, p=0.015), anxiety (HADS anxiety, p<0.001), and stress (PSS, p=0.001). Unexpectedly, weekday sleep quality (Pittsburgh Sleep Quality Index) worsened in the healthcare group (p=0.013). The IT group showed no significant changes, possibly due to the small sample size. Physiological measurements revealed significant differences between groups post-intervention, including melatonin levels (p=0.001) and electrocardiogram values (p=0.031), suggesting occupation-specific responses to VR interventions.
Conclusion
Despite limitations such as unequal sample sizes, this study provides valuable insights into the potential of VR-based stress management programs. The findings underscore the need for occupation-specific approaches and further research with larger, balanced samples to validate these results and explore long-term effects.
6.Pilot Trial: Impact of a Virtual Reality Stress Reduction Program on Healthcare and Information Technology Professionals During the COVID-19 Pandemic
Daeho KWON ; Wooyoung IM ; Yunsoo KIM ; Jaesung YOO ; Huisu JEON ; Heeyong CHOI ; Hyeyun KIM
Psychiatry Investigation 2025;22(4):451-461
Objective:
This study evaluated the effectiveness of a virtual reality (VR) based stress reduction program tailored for healthcare and information technology (IT) professionals during the coronavirus disease-2019 pandemic.
Methods:
The 2-week program, based on forest healing principles, was designed to alleviate occupational stress and improve sleep quality. Participants (n=54; 46 healthcare, 8 IT professionals) underwent pre- and post-intervention assessments using validated psychological scales and physiological measurements.
Results:
Results showed significant reductions in stress (Perceived Stress Scale [PSS], p=0.001) and anxiety (Hospital Anxiety and Depression Scale [HADS] anxiety, p=0.002) across all participants. Healthcare professionals demonstrated significant decreases in depression (Patient Health Questionnaire-9, p=0.015), anxiety (HADS anxiety, p<0.001), and stress (PSS, p=0.001). Unexpectedly, weekday sleep quality (Pittsburgh Sleep Quality Index) worsened in the healthcare group (p=0.013). The IT group showed no significant changes, possibly due to the small sample size. Physiological measurements revealed significant differences between groups post-intervention, including melatonin levels (p=0.001) and electrocardiogram values (p=0.031), suggesting occupation-specific responses to VR interventions.
Conclusion
Despite limitations such as unequal sample sizes, this study provides valuable insights into the potential of VR-based stress management programs. The findings underscore the need for occupation-specific approaches and further research with larger, balanced samples to validate these results and explore long-term effects.
7.A Spontaneous Coronary Artery Dissection Autopsy in a 64-Year-Old Male
Sang Won LEE ; Wooyoung JANG ; Tae Mo KANG ; So Youn IM ; Kyungmin LEE ; Kwang Soo KO ; Jinhyuk CHOI
Korean Journal of Legal Medicine 2025;49(2):51-55
Spontaneous coronary artery dissection (SCAD) is a condition in which an intramural hematoma within the coronary artery leads to acute coronary syndrome without atherosclerosis, trauma, or iatrogenic causes. It predominantly affects middle-aged women and is associated with several predisposing conditions, including fibromuscular dysplasia, systemic inflammatory disorders, connective tissue diseases, and coronary artery spasms. We report the case of a 64-year-old male with a history of hypertension who died of SCAD. His death occurred suddenly and without preceding trauma while the decedent was working overtime at a construction site. On gross examination, a thrombus-like material was identified in a branch of the left anterior descending artery and was initially presumed to be a postmortem clot. However, microscopic examination revealed an intramural hemorrhage, medial dissection, and formation of a false lumen within the coronary artery. This case report highlights the importance of a thorough histopathological examination of the coronary arteries during autopsy, even in the absence of atherosclerosis.
8.Pilot Trial: Impact of a Virtual Reality Stress Reduction Program on Healthcare and Information Technology Professionals During the COVID-19 Pandemic
Daeho KWON ; Wooyoung IM ; Yunsoo KIM ; Jaesung YOO ; Huisu JEON ; Heeyong CHOI ; Hyeyun KIM
Psychiatry Investigation 2025;22(4):451-461
Objective:
This study evaluated the effectiveness of a virtual reality (VR) based stress reduction program tailored for healthcare and information technology (IT) professionals during the coronavirus disease-2019 pandemic.
Methods:
The 2-week program, based on forest healing principles, was designed to alleviate occupational stress and improve sleep quality. Participants (n=54; 46 healthcare, 8 IT professionals) underwent pre- and post-intervention assessments using validated psychological scales and physiological measurements.
Results:
Results showed significant reductions in stress (Perceived Stress Scale [PSS], p=0.001) and anxiety (Hospital Anxiety and Depression Scale [HADS] anxiety, p=0.002) across all participants. Healthcare professionals demonstrated significant decreases in depression (Patient Health Questionnaire-9, p=0.015), anxiety (HADS anxiety, p<0.001), and stress (PSS, p=0.001). Unexpectedly, weekday sleep quality (Pittsburgh Sleep Quality Index) worsened in the healthcare group (p=0.013). The IT group showed no significant changes, possibly due to the small sample size. Physiological measurements revealed significant differences between groups post-intervention, including melatonin levels (p=0.001) and electrocardiogram values (p=0.031), suggesting occupation-specific responses to VR interventions.
Conclusion
Despite limitations such as unequal sample sizes, this study provides valuable insights into the potential of VR-based stress management programs. The findings underscore the need for occupation-specific approaches and further research with larger, balanced samples to validate these results and explore long-term effects.
9.Pilot Trial: Impact of a Virtual Reality Stress Reduction Program on Healthcare and Information Technology Professionals During the COVID-19 Pandemic
Daeho KWON ; Wooyoung IM ; Yunsoo KIM ; Jaesung YOO ; Huisu JEON ; Heeyong CHOI ; Hyeyun KIM
Psychiatry Investigation 2025;22(4):451-461
Objective:
This study evaluated the effectiveness of a virtual reality (VR) based stress reduction program tailored for healthcare and information technology (IT) professionals during the coronavirus disease-2019 pandemic.
Methods:
The 2-week program, based on forest healing principles, was designed to alleviate occupational stress and improve sleep quality. Participants (n=54; 46 healthcare, 8 IT professionals) underwent pre- and post-intervention assessments using validated psychological scales and physiological measurements.
Results:
Results showed significant reductions in stress (Perceived Stress Scale [PSS], p=0.001) and anxiety (Hospital Anxiety and Depression Scale [HADS] anxiety, p=0.002) across all participants. Healthcare professionals demonstrated significant decreases in depression (Patient Health Questionnaire-9, p=0.015), anxiety (HADS anxiety, p<0.001), and stress (PSS, p=0.001). Unexpectedly, weekday sleep quality (Pittsburgh Sleep Quality Index) worsened in the healthcare group (p=0.013). The IT group showed no significant changes, possibly due to the small sample size. Physiological measurements revealed significant differences between groups post-intervention, including melatonin levels (p=0.001) and electrocardiogram values (p=0.031), suggesting occupation-specific responses to VR interventions.
Conclusion
Despite limitations such as unequal sample sizes, this study provides valuable insights into the potential of VR-based stress management programs. The findings underscore the need for occupation-specific approaches and further research with larger, balanced samples to validate these results and explore long-term effects.
10.A Spontaneous Coronary Artery Dissection Autopsy in a 64-Year-Old Male
Sang Won LEE ; Wooyoung JANG ; Tae Mo KANG ; So Youn IM ; Kyungmin LEE ; Kwang Soo KO ; Jinhyuk CHOI
Korean Journal of Legal Medicine 2025;49(2):51-55
Spontaneous coronary artery dissection (SCAD) is a condition in which an intramural hematoma within the coronary artery leads to acute coronary syndrome without atherosclerosis, trauma, or iatrogenic causes. It predominantly affects middle-aged women and is associated with several predisposing conditions, including fibromuscular dysplasia, systemic inflammatory disorders, connective tissue diseases, and coronary artery spasms. We report the case of a 64-year-old male with a history of hypertension who died of SCAD. His death occurred suddenly and without preceding trauma while the decedent was working overtime at a construction site. On gross examination, a thrombus-like material was identified in a branch of the left anterior descending artery and was initially presumed to be a postmortem clot. However, microscopic examination revealed an intramural hemorrhage, medial dissection, and formation of a false lumen within the coronary artery. This case report highlights the importance of a thorough histopathological examination of the coronary arteries during autopsy, even in the absence of atherosclerosis.