In a completely edentulous patient who cannot have implant-retained overdentures due to medical history and economic circumstances, a suction-effective complete denture utilizing the closed-mouth impression technique is being used to secure high retention. In this case, both a conventional complete denture using the open-mouth impression technique and a suction-effective complete denture using the closed-mouth impression technique were fabricated for a single completely edentulous patient. The results demonstrated that both methods provided excellent outcomes in terms of function, esthetics, and patient satisfaction. Conventional complete dentures increase the area of denture-bearing pressure to ensure retention and stability, whereas suction-effective complete dentures achieve retention by sealing the entire border of the denture. Since there are characteristic differences in the clinical and laboratory procedures due to differences in the concept of denture fabrication, this was compared through this case report.

In a completely edentulous patient who cannot have implant-retained overdentures due to medical history and economic circumstances, a suction-effective complete denture utilizing the closed-mouth impression technique is being used to secure high retention. In this case, both a conventional complete denture using the open-mouth impression technique and a suction-effective complete denture using the closed-mouth impression technique were fabricated for a single completely edentulous patient. The results demonstrated that both methods provided excellent outcomes in terms of function, esthetics, and patient satisfaction. Conventional complete dentures increase the area of denture-bearing pressure to ensure retention and stability, whereas suction-effective complete dentures achieve retention by sealing the entire border of the denture. Since there are characteristic differences in the clinical and laboratory procedures due to differences in the concept of denture fabrication, this was compared through this case report.

In a completely edentulous patient who cannot have implant-retained overdentures due to medical history and economic circumstances, a suction-effective complete denture utilizing the closed-mouth impression technique is being used to secure high retention. In this case, both a conventional complete denture using the open-mouth impression technique and a suction-effective complete denture using the closed-mouth impression technique were fabricated for a single completely edentulous patient. The results demonstrated that both methods provided excellent outcomes in terms of function, esthetics, and patient satisfaction. Conventional complete dentures increase the area of denture-bearing pressure to ensure retention and stability, whereas suction-effective complete dentures achieve retention by sealing the entire border of the denture. Since there are characteristic differences in the clinical and laboratory procedures due to differences in the concept of denture fabrication, this was compared through this case report.

In a completely edentulous patient who cannot have implant-retained overdentures due to medical history and economic circumstances, a suction-effective complete denture utilizing the closed-mouth impression technique is being used to secure high retention. In this case, both a conventional complete denture using the open-mouth impression technique and a suction-effective complete denture using the closed-mouth impression technique were fabricated for a single completely edentulous patient. The results demonstrated that both methods provided excellent outcomes in terms of function, esthetics, and patient satisfaction. Conventional complete dentures increase the area of denture-bearing pressure to ensure retention and stability, whereas suction-effective complete dentures achieve retention by sealing the entire border of the denture. Since there are characteristic differences in the clinical and laboratory procedures due to differences in the concept of denture fabrication, this was compared through this case report.

In a completely edentulous patient who cannot have implant-retained overdentures due to medical history and economic circumstances, a suction-effective complete denture utilizing the closed-mouth impression technique is being used to secure high retention. In this case, both a conventional complete denture using the open-mouth impression technique and a suction-effective complete denture using the closed-mouth impression technique were fabricated for a single completely edentulous patient. The results demonstrated that both methods provided excellent outcomes in terms of function, esthetics, and patient satisfaction. Conventional complete dentures increase the area of denture-bearing pressure to ensure retention and stability, whereas suction-effective complete dentures achieve retention by sealing the entire border of the denture. Since there are characteristic differences in the clinical and laboratory procedures due to differences in the concept of denture fabrication, this was compared through this case report.

The authors present a 67-year-old man who developed trigeminal neuralia caused by a dolichoectatic vertebrobasilar artery. Brain magnetic resonance imaging showed a tubular structure traversed the anterior surface of the sbrainstem, which compressed the left ven trilateral pons in the region of the trigeminal root entry zone. Vertebral angiography demonstrated a tortuous dilated vertebrobasilar artery. Microvascular decompression of the trigeminal nerve from the dolichoectatic vertebral artery and simultaneous selective trigeminal rhizotomy were performed. Postoperatively, the patient was relieved of pain but suffered a hearing deficit in the ipsilateral side.
Aged ; Angiography ; Arteries ; Brain ; Hearing ; Humans ; Magnetic Resonance Imaging ; Microvascular Decompression Surgery ; Pons ; Rhizotomy ; Trigeminal Nerve ; Trigeminal Neuralgia* ; Vertebral Artery*

BACKGROUND: A management protocol for hepatitis C virus (HCV) after liver transplantation (LT) has not been established in Korea. We therefore investigated HCV transplant protocols and post-transplant results from liver transplant centers in Korea. METHODS: The HCV protocol and medical data of individual cases from eight major liver transplant centers were compiled and analyzed. RESULTS: A post-transplant protocol biopsy was performed in only three centers. In these centers, HCV treatment was considered when pathological abnormalities were confirmed on the protocol biopsy (irrespective of liver function). In the other five centers, biopsies were performed when biochemical parameters were aggravated. Only two out of the eight centers performed preemptive or prophylactic therapy. A total of 5,663 adult LTs were performed between 2000 and 2010. HCV-related liver disease was responsible for 277 LTs (4.9%). Pre-transplant data were not available in many patients, including HCV genotype and serum HCV RNA level. Tacrolimus was more frequently used for initial maintenance immunosuppression than cyclosporine A (61.7% vs. 36.8%). Post-transplant HCV treatment was performed in 135 patients (48.7%). Sixty-seven recipients (24.2%) died during follow-up after LT and 11 HCV-related graft loss (4.0%) developed. The cumulative patient survival rate was 74.7% at 5 years and 67.9% at 10 years after LT. CONCLUSIONS: The HCV management protocol after LT varied markedly between the eight Korean transplant centers and a standard protocol did not exist. A nationwide multicenter study is required to investigate the most effective treatment for HCV after LT, with the goal of establishing the most effective standard protocol.
Adult ; Biopsy ; Cyclosporine ; Follow-Up Studies ; Genotype ; Hepacivirus ; Hepatitis ; Hepatitis C ; Humans ; Immunosuppression ; Korea ; Liver ; Liver Diseases ; Liver Transplantation ; RNA ; Survival Rate ; Tacrolimus ; Transplants

Cordyceps bassiana has long been used as an oriental medicine and reported to possess diverse biological activities. The fruiting bodies of Cordyceps bassiana was extracted with ethanol and then further fractionated with n-hexane, ethyl acetate, n-butanol and water. The butanol fraction from Cordyceps bassiana (CBBF) exhibited the most effective in anti-inflammatory activity in RAW 264.7 macrophages and the roles of CBBF on the anti-inflammation cascade in LPS-stimulated RAW 264.7 cells were studied. To investigate the mechanism by which CBBF inhibits NO, iNOS and COX-2, the activation of IκB and MAPKs in LPS-activated macrophage were examined. Our present results demonstrated that CBBF inhibits NO production and iNOS expression in LPS-stimulated RAW 264.7 macrophage cells, and these effects were mediated through the inhibition of IκB-α, JNK and p38 phosphorylation. Also, CBBF suppressed activation of MAPKs including p38 and SAPK/JNK. Furthermore, CBBF significantly suppressed LPS-induced intracellular ROS generation. Its inhibition on iNOS expression, together with its antioxidant activity, may support its anti-inflammatory activity. Thus Cordyceps bassiana can be used as a useful medicinal food or drug for further studies.
1-Butanol ; Cordyceps* ; Ethanol ; Fruit ; Inflammation* ; Macrophages ; Medicine, East Asian Traditional ; Phosphorylation ; RAW 264.7 Cells* ; Water

A 56-year-old male underwent a screening colonoscopy. An 8-mm sessile polyp was removed from the descending colon using snare polypectomy. Histology showed Langerhans cells and eosinophil infiltration of the submucosa. Immunohistochemical staining was positive for S-100 protein and CD1a antigen, which confirmed the diagnosis of Langerhans-cell histiocytosis. On further workup, there was no evidence of involvement of any other organs. Here, we report a very rare case of colonic Langerhans-cell histiocytosis presenting as an isolated polyp.
Antigens, CD1 ; Colon ; Colon, Descending ; Colonoscopy ; Eosinophils ; Histiocytosis, Langerhans-Cell ; Humans ; Langerhans Cells ; Male ; Mass Screening ; Polyps ; S100 Proteins ; SNARE Proteins

PURPOSE: Serious complications from snake bite envenomization are relatively rare in Korea. According to standrad treatment guidelines for local and systemic injuries, antivenin is not recommended for snake bite cases when victims show minimal clinical symptoms. However, there are no published stidies about the effectiveness of antivenin treatment in such cases in Korea. In order to provide actual documentation to support a standard for treatment, we evaluated the effectiveness of antivenin use by comparing clinical outcomes in snake bite patients exhibiting minimal clinical symptoms (traditional snake bite severity grades 0 and I). METHODS: We retrospectively reviewed 140 snake bite cases of patients with minimal clinical symptoms who visited the emergency departments of Chungnam National University Hospital, Cheonan Medical Center, and Chungnam Seosan Medical Center in Korea from January 2000 to December 2006. We categorized the patients into antivenin (group 1) and non-antivenin (group 2) treatment groups. We compared clinical outcomes and characteristics of the two groups. RESULTS: Neither demographic factors nor clinical outcomes showed statistical significance between the groups. CONCLUSION: In case of snake bite victims in Korea, antivenin treatment should not generally recommended as treatment for victims exhibiting minimlal clinical symptoms.
Antivenins ; Chungcheongnam-do ; Demography ; Emergency Service, Hospital ; Humans ; Korea ; Retrospective Studies ; Snake Bites* ; Snakes* ; Treatment Outcome