1.A study to the workers exposed to organic solvents by neurobehavioral tests.
Seong Kyu KANG ; Ho Keun CHUNG ; Jeong Pyo HONG ; Ki Woong KIM ; Young Sook CHO
Korean Journal of Preventive Medicine 1993;26(2):210-221
In order to evaluate the confounding factors of neurobehavioral tests and the neurobehavioral effects in the workers exposed to organic solvents, NCTB was carried out on 100 workers. 46 workers had never been exposed to neurotoxic substances, and the others were being exposed to the solvents, mainly toluene. Simple reaction time, digit symbol, Santa Ana dexterity test and persuit aiming were different with age in non exposure group. Simple reaction time was carried out well in males, and digit symbol and persuit aiming were in females. There was no difference at educational level when the subject was educated over 12 years. Santa Ana dexterity and Benton visual test differed according to exposure level to toluene, however simple reaction time didn't. The acute neurotoxic effect was not excluded in this study. But, NCTB could be used to evaluate and prevent neurobehavioral changes in workers exposed to neurotoxic solvents in Korea.
Female
;
Humans
;
Korea
;
Male
;
Reaction Time
;
Solvents*
;
Toluene
2.Correction of pseudoptosis occurred after blepharoplasty.
Seon Woong KIM ; Yeon Soo KIM ; In Pyo HONG ; Jong Whan KIM ; Young Ho KIM
Journal of the Korean Society of Aesthetic Plastic Surgery 2000;6(2):109-113
No Abstract Available.
Blepharoplasty*
3.Bladder Preservation by Combuned Modality Therapy for Invasive Bladder Cancer: A Five-Year Follow-up.
Jae Ho CHO ; Jihoon LIM ; Jinsil SEONG ; Hong Ryull PYO ; Woong Soup KOOM ; Chang Ok SUH ; Sung Jun HONG
The Journal of the Korean Society for Therapeutic Radiology and Oncology 2001;19(4):359-368
No absract available.
Follow-Up Studies*
;
Urinary Bladder Neoplasms*
;
Urinary Bladder*
4.Usefulness of Artificial Dermis ( Alloderm and Terudermis ) for Reconstruction of Soft Tissue Defect.
Seon Woong KIM ; Yeon Soo KIM ; In Pyo HONG ; Jong Whan KIM
Journal of the Korean Society of Plastic and Reconstructive Surgeons 2000;27(6):653-658
There remains many difficult problems for plastic surgeons when they try to reconstruct soft tissue defect, especially defect on lower extremity with poor vascularity. We experienced two kinds of artificial dermis, Alloderm (LifeCell Corporation, USA) and Terudermis(Terumo, Japan). We applied them for 12 patients from October 1998 to May 1999. Their wounds had various causes. The authors debrided the necrotic tissue and got the artificial dermis soaked enough in saline. After fixing the artificial dermis with suture fixation, thin STSG was harvested. Applying the thin STSG on artificial dermis and Tie-over dressing were done to prevent mobilization. From our experience we had several suggestions to keep in mind. Preoperatively, you have to decrease the discharge with frequent dressing change. Intraoperativeiy, in order to avoid the mobilizaion between the artificial dermis and STSG, you have to fix them well with suture fixation. Postoperatively, the larger is the exposed bone or tendon, the longer the splint applying time is required. Nine patients out of 12 patients(75%) had no problem. Three patients underwent partial loss. Two patients suffered from infection or rough dressing. One patient failed due to careless mobilization before the artificial dermis is completely settled. The authors recommend to appky the artificial dermis rather than more aggressive procedures when the wound size is smaller than 2 x 4 cm with bone or tendon exposure. The authors think that the artificial dermis is also very useful to prevent postoperative scar contracture.
Bandages
;
Cicatrix
;
Contracture
;
Dermis*
;
Humans
;
Lower Extremity
;
Splints
;
Sutures
;
Tendons
;
Wounds and Injuries
5.Population pharmacokinetics and bayesian feedback method for nortriptyline dosage optimisation.
Sang Goo SHIN ; Jong Inn WOO ; In Jin JANG ; Chan Woong PARK ; Jae Jin KIM ; Jin Pyo HONG ; Kyeong Hun LEE
Journal of Korean Neuropsychiatric Association 1992;31(5):884-894
No abstract available.
Nortriptyline*
;
Pharmacokinetics*
6.The Preliminary Study on the Validation of Schizotypal Personality Questionnaire-Korean Version.
Hee Ok MOON ; Ik Hong YANG ; Heung Pyo LEE ; Myo Eun KIM ; Woong HAM
Journal of Korean Neuropsychiatric Association 1997;36(2):329-343
In order to product and develop questionnaire which can assess the schizotypal personality by model of criteria in DSM-III-R it was presented 1311owing questions in this study. First, far the validation and manufacture of scale and sub-subscale that assess overall feature, nine characteristics of the schizotypal personality disorder, this study was concerned with validity, reliability and factor-analysis results of schizotypal personality questionnaire. Second, we would be present how schizotypal personality disorder trend is connected with trait-anxiety, hopelessness and self-concept. Also the difference Is compared with. Finally, 396(male 216 Ss/53,8%, female 180 Ss/45.5%) college students with mean age 21.2 years were sampled. Raine's schizotypal personality questionnaire(SOQ) which assess nine characterisitics of schizotypal personality disorder in DSM-III-R was translated and used. In this results, Raine's schizotypal personality questionnaire was appeared to have high internal validity, split-half reliability and test-retest reliability Also, 6 factors were affirmed by empirical confirmation through factor-analysis. 6 factors have been very reliable internal validity that ranges from .78 to .83. In these 6 factors, idea of reference, odd or eccentric behavior and odd speech were corresponded to the category model after DSM-III-B in Raine's scale. 'Cognitive, perceptive' dimension was centered of factor 1, 'Emotive, affective' dimension was centered of factor 2, social anxiety and constricted affect were constituted to 2nd factor. No close friends, schizoid trend and suspiciousness of schizotypal characteristics were constituted to 3rd factor by' interpersonal relationship' dimension. These empirical outcomes which confirmed through factor-analysis were very valid and connected much to Raine's scale which assessed schizotypal personality disorder, thus possibility of development and manufacture of schizotypal personality disorder scale through item revision was lighten. In 2nd study the higher schizotypal personality disorder trend, trait-anxiety and hoplessness were higher. But on the contrary, self-concept was lower. The group of high score in schizotypal personality questionnaire had more trait-anxiety and hopelessness than the group of low score in schizotypal personality questionnaire. Contrastly, positive self-concept was high in the group of low score. Also, the most predictable variable to the trait-anxiety was factor 2, predictable power R2 of factor 2 was 29.1%. To the hopelessness, factor 2 was the most powerful predictable variable. Predictable power of factor 2 was 11.2%, also. In self-concept, factor 2 explained 20.8% of self-concept, thus it was presented that factor 2 had the most powerful explanatory quantity. In these consequences, the factors which have meaningful connection to the trait-anxiety, hopelessness and low self-concept within 6 factors were really factor 2, 3, 1. Among these factors, 'Emotive' feature of factor 2 including social anxiety and constricted affect have the most effect on trait-anxiety, hopelessness and serf-concept. And next to factor 2, the isolated interpersonal relation which include no close friends and schizoid trend was some influential variable. Also peculiar, unusual perceptual experience, eccentric belief and magical thinking had some effect though small. The college students who had strong schizotypal personality trend had more social anxiety and more constricted emotional empathic ability, less self-expression, less social skill than common college students. These elements threaten, interrupt and retard identity establishment and intimacy-seeking which are important developmental tasks within this period. These experiences is accepted to ego-dystonic to schizotypal college students who have some or moderate reality testing, adaptive ability. Moreover, These peoples would feel locus of control externally, not internally and would have more control-failure experiences. All these elements elevate anxiety level, give rise to low self-concept and low expectation to the future. These outcomes all confirmed questions which presented in this study.
Anxiety
;
Female
;
Friends
;
Humans
;
Internal-External Control
;
Interpersonal Relations
;
Magic
;
Surveys and Questionnaires
;
Reality Testing
;
Schizotypal Personality Disorder
;
Thinking
7.A Case of Scalp Neurothekeoma.
Sang Keun PARK ; Seon Woong KIM ; Jong Hwan KIM ; In Pyo HONG ; Hee Jin CHANG
Journal of the Korean Society of Plastic and Reconstructive Surgeons 2001;28(4):435-438
Neurothekeoma is a relatively uncommon tumor of nerve sheath origin. Most of these tumors are benign and malignant transformation was not reported. Usually, these tumors arise during childhood or early adulthood life with female preponderance. They have a predilection for the head, neck and shoulder region but any part of the body may be affected. Their usual size is between 0.5-3.0 cm. Rapid growth and ulceration are rare, and local recurrence tends to occur after incomplete excision. We report a case of neurothekeoma developed in the scalp of a 21-year-old woman. It was first noticed about 1year ago. This mass had been increasing in size slowly. On physical examination, 2 x 1.5 cm sized papule with localized alopecia was identified on the frontal scalp area. It was excised in 5.5 x 3.6 cm. The histologic finding of the lesion showed that lobules, fascicles or rests of spindle shaped or epitheloid cells in a myxoid of mucosubstance. The tumor cells were positive for S-100 and vimentin but showed negative for EMA, cytokeratin, desmin, actin and HMB45. After surgical excision of tumor, split-thickness skin graft was done. Three months after the operation, rectangular shape tissue expander (180 cc Sebbin(R)) was inserted on both sides of the previous wound. After removal of tissue expander, the wound closed with local flap. The patient did not have any evidence of recurrence for 6 months.
Actins
;
Alopecia
;
Desmin
;
Female
;
Head
;
Humans
;
Keratins
;
Neck
;
Neurothekeoma*
;
Physical Examination
;
Recurrence
;
Scalp*
;
Shoulder
;
Skin
;
Tissue Expansion Devices
;
Transplants
;
Ulcer
;
Vimentin
;
Wounds and Injuries
;
Young Adult
8.Assessment of Occupational Exposure to Cadmium in Korea.
Seong Kyu KANG ; Jeong Pyo HONG ; Ki Woong KIM ; Jae Yeon JANG ; Ho Keun CHUNG ; Kyou Chull CHUNG
Korean Journal of Occupational and Environmental Medicine 1994;6(2):252-258
Twenty-four factories registered at the Ministry of Labor as factories using or producing cadmium in 1991 were investigated to know the present state of occupational exposure to cadmium in 1992. Nine factories among 24 stopped using or changed to other substances and 1 factory didn't produce any more, but delivered it to other factories through imports. Therefore, only 14 factories were producing or using cadmium. But, alloying materials were uspplied to about 20 and more factories, however, they couldn't be investigated because of limited information. Three factories had less than 50 workers were 3, 6 had 50-300 and 5 had more than 300. About 167 workers were exposed to cadmium. According to the classification by process, there were 4 alloy processes, 2 refinary, 2 elctroplating, 2 dry cell making, 1 industrial battery and 1 copper refinary. 8 factories used metal cadmium, 3 cadmium oxide, 2 cadmium sulfide, and 1 cadmium hyroxide. One factory was importing cadmium stearates only and supplying them to the PVC making factories. The amount of metal cadmium producing in 2 refinary factories was about 50-65 ton per month. The other cadmium compounds were imported. According to exposure level of cadmium in air of the 10 factories examined, each factory could be divided into high, moderate and low exposure groups. 1 battery recycling factory and 3 alloy factories were in the high exposure group and their mean air concentrations were 0.06679, 0.05481, 0.02492, and 0.003mg/m3, respectively. Refinary and industrial battery making factories were in the middle exposure group and their mean air concentrations were 0.00773 and 0.00613 mg/m3, respectively. Finally, low exposure group were copper smelting, dry cell case making, duplicator drum making and electroplating factory and their mean air concentrations were 0.00096, 0.00071, 0.00057 and 0.00054 mg/m3 respectively.
Alloys
;
Cadmium Compounds
;
Cadmium*
;
Classification
;
Copper
;
Electroplating
;
Korea*
;
Occupational Exposure*
;
Osmeriformes
;
Recycling
;
Stearates
9.Effects of Dimethyl Sulfoxide (DMSO) on the Contraction of the Rat Iris Muscle.
Yoon hee KIM ; Sang hoon RAH ; Hyun woong SHIN ; Wook pyo HONG
Journal of the Korean Ophthalmological Society 2001;42(7):1096-1101
PURPOSE: To evaluate the effects of DMSO on the iris muscle contractility and to compare DMSO with other detergents(ethanol and triton-x 100). METHODS: After anesthesizing rats with an intraperitoneal injection of pentobarbital sodium, each animal was fixed under microscope. The pupil response to the drugs was examined by CCD camera and the video edge motion detector was used for measurement of alteration of the pupil size. The pupil response to the drugs was recorded by MacLab chart(version 3.6/s). RESULTS: Miosis induced by DMSO was initiated after 5 minutes, peaked at around 30 minutes and maintained until 3 hours after instillation. Miotic effect of DMSO was in a dose dependent manner ranging 0.01%-10% and was not reversed after washout. All detergents used in the present experiment induced miosis, however, DMSO elicited the strongest miotic response. After pretreatment with atropine, DMSO-induced miotic response was not affected, showing similar changes with control group. CONCLUSIONS: Taken together, it is concluded that DMSO induces miosis by inducing relaxation of iris dilator muscle.
Animals
;
Atropine
;
Detergents
;
Dimethyl Sulfoxide*
;
Injections, Intraperitoneal
;
Iris*
;
Miosis
;
Miotics
;
Pentobarbital
;
Pupil
;
Rats*
;
Relaxation
10.Osteoma after Reduction Malarplasty.
Shang Back SHIM ; Jong Hwan KIM ; In Pyo HONG ; Seon Woong KIM
Journal of the Korean Society of Aesthetic Plastic Surgery 2002;8(1):37-40
Osteoma is a benign tumor arising from cancellous or compact bone. Frontal sinus is the most common site, followed by the ethmoidal sinus, maxillary sinus, sphenoidal sinus, maxilla and mandible. Very few cases involving the mandible have been described. A 26-year-old woman who had a limited range of mouth opening was reffered to our clinic. The limited opening had been gradually increasing in severity after first operation(reduction malarplasty and angle resection). Computed tomography images showed a radiopaque mass between left mandibular notch and zygomatic arch. After surgical removal of mass, diagnosis of mass was osteoma from clinical pathology. The postoperative course was uneventful, the patient could open the mouth about 40 mm, 5 months after the operation.
Adult
;
Diagnosis
;
Female
;
Frontal Sinus
;
Humans
;
Mandible
;
Maxilla
;
Maxillary Sinus
;
Mouth
;
Osteoma*
;
Pathology, Clinical
;
Sphenoid Sinus
;
Zygoma