We assessed the accuracy of Goldmann or Schi-(phi)tz tonometric readings in the gas filled vitrectomized eyes. We performed pars plana vitrectomy with or without lensectomy in 8 rabbit eyes, and in 6 enucleated porcine eyes. Fluid-air exchange was done at the end of the procedure. Intraocular pressure was measured using Goldmann tonometer and Schi-(phi)tz tonometer and was compared with true pressure which was monitored by manometer with indwelling catheter in the intravitreal cavity. Goldmann and Schi-(phi)tz tonometry always showed lower presure value than manometeric one(P<0.05) and the discrepancy was greater at higher range of intraocular pressure. Between these two methods Goldmann tonometry was more accurate in the rabbit eye (P>0.05).
Catheters, Indwelling ; Intraocular Pressure* ; Manometry ; Reading ; Vitrectomy

One of the complication during or after subclavian vein cannulation is intravascular catheter or wire embolization. Although some studies have reported safety of retaining foreign body embolization, and even death. The intravascular foreign body can be removed surgically or non-surgically. With improvement in instrument technology and technique, percutaneous retrieval of intravascular foreign bodies has become a relatively common procedure. Commonly used methods to remove intravascular foreign bodies are loop snare and basket technique. Sometimes biopy forcep can be used. We have experienced 2 cases of non-surgical removal of intravascular foreign bodies. One of the foreign bodies was 7cm wire fragment in right atrium(RA), the other was a 50cm guide wire. We used the standard loop snare technique for removal of 7cm wire fragment in RA and stone removal basket and 3.0mm ACS PTCA balloon to remove the 50cm short guide wire.
Catheterization ; Catheters ; Foreign Bodies* ; SNARE Proteins ; Subclavian Vein ; Surgical Instruments

No abstract available.
Animals ; Astrocytes* ; Interleukin-1* ; Interleukin-10* ; Interleukin-12* ; Interleukin-1beta* ; Interleukin-2* ; Interleukin-6* ; Melanoma* ; Mice* ; Mycoplasma pneumoniae* ; Mycoplasma* ; Pneumonia, Mycoplasma*

In this study, the distribution and reisolation of Mycoplasma pneumoniae(Mp) were observed from the various tissues of BALB/c mice which were intraperitoneally pre-inoculated with Mp. In addition, the effect of Mp on the growth, phagocytic activities and nitric oxide production of microglial cells were also examined. The results were as follows; 1) Mp was reisolated from the various tissues such as lymph node, spleen, liver, kidney, brain and blood from one hour through 48 hours after intra-peritoneal inoculation of Mp in mice by the cultural method. Furthermore, it could also be confirmed from those tissues up to 72 hours by the indirect immunofluorescent antibody method. 2) There was no difference in the phagocytic activities between the control microglial cells and Mp stimulated microglial cells. 3) The growth of microglial cells in the medium was significantly increased by the stimulation with Mp compared with that of the control. 4) Nitric oxide production of mouse microglial cells was increased by the combined treatment if IFN-r and LPS or IFN-r and Mp or IFN-r, LPS and Mp, whereas, no increase was observed by either LPS or Mp alone. 5) Nitric oxide production of microglial cells primed with IFN-r was closely related with the dose of LPS and Mp in the dose dependent manner rather than that of the IFN-r. These results suggest that; i) Mp spreads to the various tissues of mice within one hour after intraperitoneal inoculation, ii) the growth of microglial cells increases by the infection of Mp, iii) microglial cells have phagocytic activities to C.albicans and iv) nitric oxide production of microglial cells was augmented by the infection of Mp. Increased nitric oxide production of microglial cells is regarded as an increase of the intracellular bactericidal activiteis of microglial cells. It is suggested, nonetheless, that the inflammatory response of the Mp infected tissues is augmented by the increase of nitric oxide.
Animals ; Brain ; Kidney ; Liver ; Lymph Nodes ; Mice* ; Mycoplasma pneumoniae* ; Mycoplasma* ; Nitric Oxide* ; Pneumonia, Mycoplasma* ; Spleen

Adjustable sutures increased the rate of success with a single procedure, but sometimes fails because of changes in the angle of deviation which develops a few days after surgery. Therefore, the delayed adjustment was attempted;however, the postoperative adhesion following strabismus surgery make delayed adjustment impossible. We studied 45 eyes of 25 rabbits; adjustable strabismus surgery underwent a hang-back technique in the superior rectus muscle. In experimental group, a sponge was soaked in 5-Fluorouracil, and the sponge was placed between the conjunctiva and the sclera for 5 minutes during the operation. We studied the possible time of delayed adjustment and estimated the minimal forces required for the adjustment. The experimental group A (5-Fluorouracil, 50mg/ml) allowed for a 6 day delayed adjustment after surgery, control group allowed for a 2 day delayed adjustment after surgery. These results suggest that 5-Fluorouracil may valuable resource to delayed adjustment strabismus surgery by reduce postoperative adhesion.
Conjunctiva ; Fluorouracil* ; Porifera ; Rabbits ; Sclera ; Strabismus* ; Sutures

The purpose of this study was to evaluate the surface roughness of Ni-Cr-Be alloy(Verabond ~, Aalba Dent Inc. USA) according to electrolyte concentration and etching time. Total of 150 metal specimens (12x 10 X 1.5mm) composed of 5 polisded specimens, 5 sandblasted specimens, 140 etched specimens were prepared. Etched groups were divided into 28 groups by the HC1O4 con= centrations(10, 30, 50, 70%) and etching times(15, 30, 60, 120, 180, 240, 300 seconds). The mean surface roughness(Ra) and the etching depth were measured with Optical 3-dimensional surface roughness measuring machine(Accura 1500M, Intek Engineering Co., Korea) and observed under SEM. The results obtaind were as follows 1. Surface roughness(Ra) and etching depth were affected by the order of etching time, electrolyte concentration, and their interaction (NO.05) . 2. Surface roughness(Ra) and etching depth were increased with etching time in 10%, 30% electrolyte concentrations, but they had no significant difference with etching time in 70%(P<0.05). 3. Surface roughness(Ra) and etching depth decreased in the order of 30, 10, 50, 70% electrolyte concentrations from 120 seconds etching time(p<0.05). 4. The remarkable morphologic changes in etched surface were observed along the grain boundaries in 15, 30 seconds of 10%, 30% concentrations and the morphologic changes could be denoted in the grains themselves as well as along the boundaries with the lapse of time. Even though the noticeable morphologic changes also took place in etched surface with 50% concentration, the degree of changes were less than that of changes with 10%, 30%. However, there were little morphologic changes with 70% concentration regardless of etching time. 5. Surface roughness(Ra) of sandblasting group with 50um A1203 had no significant difference with 30%-30 seconds etched group(p<0.05).
Alloys* ; Edible Grain

PURPOSE: Giant retinal cyst is formed by a localized and circumscribed splitting of the retina into two layers. It may often be confused with retinal detachment. We describe three cases of giant retinal cysts associated with retinal detachment associated with uveitis, and proliferative diabetic retinopathy. METHODS: A retrospective, observational case series. RESULTS: Two cases of giant retinal cyst were associated with uveitis: one detected during pars plana vitrectomy for total retinal detachment associated with chronic uveitis, and the other detected after scleral buckling procedure for retinal detachment associated with pars planitis. These cysts completely disappeared following drainage of fluid and laser photocoagulation to the flattened cyst. A case of retinal cyst secondary to proliferative diabetic retinopathy and vitreous hemorrhage was observed to be free of complication and progression without any surgical intervention for 9 months. CONCLUSIONS: Giant retinal cyst may result from intraretinal degenerative change caused by retinal capillary ischemia, vitreous traction and intraretinal leakage from the neovascularization. The cyst is considered to be stable without treatment in some cases, and in others it may be resolved with pars plana vitrectomy, fluid drainage and laser photocoagulation.
Capillaries ; Diabetic Retinopathy ; Drainage ; Ischemia ; Light Coagulation ; Pars Planitis ; Retina ; Retinal Detachment ; Retinaldehyde* ; Retrospective Studies ; Scleral Buckling ; Traction ; Uveitis ; Vitrectomy ; Vitreous Hemorrhage

Purpose: Digital Imaging and Communications in Medicine (DICOM), a standard file format for medical imaging data, contains metadata describing each file. However, metadata are often incomplete, and there is no standardized format for recording metadata, leading to inefficiency during the metadata-based data retrieval process. Here, we propose a novel standardization method for DICOM metadata termed the Radiology Common Data Model (R-CDM). Materials and Methods: R-CDM was designed to be compatible with Health Level Seven International (HL7)/Fast Healthcare Interoperability Resources (FHIR) and linked with the Observational Medical Outcomes Partnership (OMOP)-CDM to achieve a seamless link between clinical data and medical imaging data. The terminology system was standardized using the RadLex playbook, a comprehensive lexicon of radiology. As a proof of concept, the R-CDM conversion process was conducted with 41.7 TB of data from the Ajou University Hospital. The R-CDM database visualizer was developed to visualize the main characteristics of the R-CDM database. Results: Information from 2801360 cases and 87203226 DICOM files was organized into two tables constituting the R-CDM. Information on imaging device and image resolution was recorded with more than 99.9% accuracy. Furthermore, OMOP-CDM and RCDM were linked to efficiently extract specific types of images from specific patient cohorts. Conclusion R-CDM standardizes the structure and terminology for recording medical imaging data to eliminate incomplete and unstandardized information. Successful standardization was achieved by the extract, transform, and load process and image classifier. We hope that the R-CDM will contribute to deep learning research in the medical imaging field by enabling the securement of large-scale medical imaging data from multinational institutions.

Malignant lymphoma of the gastrointestinal tract is a rare lesion, which comprises 1~4% of the malignant neoplasms of the gastrointestinal tract. Abdominal pain and weight loss are the most common symptoms and an abdominal mass, the most common physical finding. This tumor is often discovered at a late stage; a diagnosis should be done on all patients undergoing an emergency operation for an obstruction, hemorrhage, or perforation. We report a case of a multiple ulcerating malignant lymphoma of the gastrointestinal tract with perforation in a 60 year-old male. The patient visited our hospital because of a sudden onset of acute abdominal pain. The operative finding was multiple masses on the small bowel, sigmoid colon, and stomach, plus multiple perforations of the small bowel. We performed a multiple small bowel segmental resection and an anastomosis at the site of the perforated lesion. The pathologic evaluation diagnosed it as a malignant lymphoma and the patient was treated with cyclophosphamide, adreiamycin, and vincristine. We report this rare disease with a review of the literature.
Abdominal Pain ; Colon, Sigmoid ; Cyclophosphamide ; Diagnosis ; Emergencies ; Gastrointestinal Tract* ; Hemorrhage ; Humans ; Lymphoma* ; Male ; Middle Aged ; Rare Diseases ; Stomach ; Ulcer* ; Vincristine ; Weight Loss

Report of right atrial thrombus complicating pulmonary embolism after cardiac surgery is rare. A 54-year-old woman operated on the atrial septal defect 10 months ago was admitted for left pleuritic pain and dyspnea. Multiple segmental perfusion defects were detected in lung perfusion scan. Transesophageal echocardiography showed a large mobile right atrial mass attached to the free wall of the right atrium with a stalk. Despite the intravenous heparinization for 13 days, follow-up echocardiography revealed the right atrial mass had not diminished in size. The mass which was confirmed as an organizing thrombus was excised under cardiopulmonary bypass. The patient recovered uneventfully and was discharged on warfarin therapy.
Cardiopulmonary Bypass ; Dyspnea ; Echocardiography ; Echocardiography, Transesophageal ; Female ; Follow-Up Studies ; Heart Atria ; Heart Septal Defects, Atrial* ; Heparin ; Humans ; Lung ; Middle Aged ; Perfusion ; Pulmonary Embolism* ; Sutures* ; Thoracic Surgery ; Thrombosis* ; Warfarin