1.A Case of Adenomyotic Cyst Within Myometrium Accompanied with Endometriosis.
Won Yeon JANG ; Chul Sung BAE ; Jae Chul SIM ; Hae Won YOON ; Me Woon KIM
Korean Journal of Gynecologic Oncology and Colposcopy 2000;11(3):318-321
Adenomyotic cyst is very rare disease, their sizes are mostly lesser 5mm. The intrauterine adenomyotic cyst may arise from progressive expansion of cyst due to progressive menstrual bleeding. Authors experienced a case of large adenomyotic cyst within myometrium occuring in a l9-year-old woman, and who was accompanied with endometriosis. The cyst was about 3 x 3em sized, and had chocolate colored thick viscous contents, We experienced one case of adenomyotic cyst which was thought to be degenerated uterine myoma, so we report the case with a brief review of the concerned literatures.
Animals
;
Cacao
;
Endometriosis*
;
Female
;
Hemorrhage
;
Humans
;
Leiomyoma
;
Mice
;
Myometrium*
;
Rare Diseases
2.A clinical review of the patients with upper gastrointestinal bleeding and factors influencing the prognosis.
Bong Soo LEE ; Hee Jang LEE ; Woon Sung JANG ; Chae Woen SEO ; Chul Soo KIM ; Sung Min PARK ; Yoo Hwan PARK
Journal of the Korean Academy of Family Medicine 1993;14(12):787-796
No abstract available.
Hemorrhage*
;
Humans
;
Prognosis*
3.Clinical Correlations between Duration of Epilepsy and Anticonvulsant Treatment Response in Temporal Lobe Epilepsy.
Jin Woon PARK ; Jang Sung KIM ; Jae Hyeon PARK
Journal of the Korean Neurological Association 1996;14(2):433-439
We have studied the clinical correlations between duration of epilepsy and anticonvulsant treatment response in temporal lobe epilepsy. We evaluated correlations between the duration of epilepsy before control and frequencies after six and twelve months of antiepileptic drug treatment, respectively. And we analyzed differences of epilepsy duration between no recurrence group, reduced seizure frequencies below 25% of before control frequencies and reduced seizure frequencies above 25% of before control frequecies groups respectively. We concluded that there are no positive correlations between the duration of epilepsy and seizure frequencies after antiepileptic drug treatment (Spearman correlation coefficients 0.2801 p=0.354 at six months antiepileptic drug treatment, 0.2797 p=0.355 at twelve months). We also concluded that there are no differencies of epilepsy duration between no recurrence group, group with reduced seizure frequencies below 25% of before control frequencies and group with reduced seizure frequencies above 25% of before control frequecies after six months of antlepileptic drug treatment(p=0.6511)and after twelve months of antiepileptic drug treatment (p=0.9469).
Epilepsy*
;
Epilepsy, Temporal Lobe*
;
Recurrence
;
Seizures
;
Temporal Lobe*
4.Acute Pulmonary Edema Caused by Direct Current Shock during Cardiac Surgery - A case report.
Choon Ho SUNG ; Hyuk E WHANG ; Jang Sig CHOI ; Woon Hyok CHUNG
Korean Journal of Anesthesiology 1983;16(4):449-452
There are various etilogic factors concerned in the formation of pulmonary edema but it is rare that pulmonary edema is elicited as a consequence of direct current shock. The cause of this complication is unknown. The mechanism of pulmonary edema is suspected that acute alteration or disparities in atrial or ventricular mechanical function of the heart consequent to the application of electrical discharge precipitate pulmonary congestion. A case of acute pulmonary edema following the use of direct current shock during anesthesia for mitral commissurotomy was experienced. The patient was treated with oxygen, diuretics, steroid, continuous positive pressure ventilation and partial cardiopulmonary bypass. The patient recovered without further event.
Anesthesia
;
Cardiopulmonary Bypass
;
Diuretics
;
Estrogens, Conjugated (USP)
;
Heart
;
Humans
;
Oxygen
;
Positive-Pressure Respiration
;
Pulmonary Edema*
;
Shock*
;
Thoracic Surgery*
5.A case of pheochromocytoma with electrocardiographic changes mimicking angina pectoris, and hypotensive crises.
Tae Ho JUNG ; Jae Kwon JANG ; Hong Su JUNG ; Sung Kee KIM ; Jong Woon AN ; Kyung Ho JANG ; Yong Keun JO ; Yong Koo OH
Korean Journal of Medicine 1993;45(6):801-807
No abstract available.
Angina Pectoris*
;
Electrocardiography*
;
Pheochromocytoma*
6.Allele Distribution of Human Surfactant Protein A in Otitis Media with Effusion.
Kyung Yuhl HAN ; Cheon Hwan OH ; Hyuck Soon JANG ; Jang Moog KIM ; Sung Woon KIM ; Myung Ho OH
Korean Journal of Otolaryngology - Head and Neck Surgery 2006;49(12):1145-1150
BACKGROUND AND OBJECTIVES: Surfactant protein A (SP-A) which plays a role in the innate host defense of lung is also expressed in Eustachian tube. However the genes underlying the susceptibility to otitis media with effusion (OME) are known insufficiently. The current study attempts to evaluate the difference in the allele distribution of SP-A1 and SP-A2 between normal subjects and subjects with otitis media with effusion. SUBJECTS AND METHOD: PCR-cRFLP-based methodology was used to detect SP-A genotypes in the 38 children with OME, and in the 55 normal newborns for control. RESULTS: The frequencies of specific genotypes such as 6A(2), 1A(2) were increased in OME group, but the frequency of 6A3 was increased in control group. CONCLUSION: It is presumed that SP-A alleles may be inductive (6A(2), 1A(2)) or protective (6A(3)) factors for OME. Specific genoytypes of SP-A may be an important determinant for the predisposition to OME.
Alleles*
;
Child
;
Eustachian Tube
;
Genotype
;
Humans*
;
Infant, Newborn
;
Lung
;
Otitis Media with Effusion*
;
Otitis Media*
;
Otitis*
;
Pulmonary Surfactant-Associated Protein A*
7.The Effects of Paclitaxel-Coated Nylon Thread on the Proliferative Cholangitis in a Rat.
Jae Woon CHOI ; Guang Bi JIN ; Dong Gyu LEE ; Sang Jeon LEE ; Lee Chan JANG ; Rohyun SUNG ; Dong Woon KIM ; Seon Mee PARK
Korean Journal of Hepato-Biliary-Pancreatic Surgery 2003;7(1):77-86
BACKGROUND/AIMS: Local drug delivery to the bile duct may be effective to prevent proliferative cholangitis (PC) through capability of high dose administeration with minimal systemic side effects. Paclitaxel is an anticancer drug whose side effect on the stabilization of microtubule leads to cell death. The aims of this study were to establish the proliferative cholangitis model in rat, mimicking biliary stricture in human, and to test whether paclitaxel-coated nylon thread prevents biliary stricture in a PC model of rat. METHODS: PC was induced by introducing a fine nylon thread into the bile duct in a rat from 1 week to 4 week. To evaluate the effects of paclitaxel as a locally-delivered anti-proliferative drug, dog gallbladder epithelial cells were exposed to sequential concentrations of paclitaxel (0.1microM, 1microM, 10microM, and 100microM) for 20 min. in vitro, and inhibition of proliferation was measured by (3)H-thymidine uptake assay. Paclitaxel- coated 5-0 nylon threads (1.8+/-0.5 ug/3 cm thread, measured by HPLC) were made by immersion of ethanolic paclitaxel (50 mg/ml) and evaporation of the solvent. Nylon threads were inserted into the bile duct of male Sprague-Dawley rats weighing 200~50 g. Paclitaxel (n=15) and control (n=15) groups were divided with or without paclitaxel-coating procedure. The paclitaxel effects were assessed by histomorphological examination one week after thread implantation. RESULTS: The decrease of (3)H-thymidine uptake was observed at 100microM of paclitaxel exposured for 20 minutes in the presence of epidermal growth factor (50 nM/ml) than control. PC model characterized by epithelial-glandular proliferation and fibrous thickening of the bile duct wall through 1~ week. This model was established at 1 week. The effect of paclitaxel-coated nylon thread into the bile duct were evaluated after 1 week. In paclitaxel treated the luminal area, luminal length and the ratio of lumen to bile duct cross sectional area increased by 276% (p=0.044), 87% (p=0.012) and by 330% (p=0.000), respectively, versus control. The total wall area, epithelial-glandular area, and stromal area were similar between paclitaxel treated group and control (p>0.05). The bile duct wall thickness of paclitaxel group decreased by 33% (p=0.011, 273 (90)microM vs 410 (95)microM, paclitaxel vs control). CONCLUSION: Paclitaxel-coated nylon thread into bile duct was effective for the suppression of luminal stenosis, and may offer a therapeutic option for biliary stricture and biliary stricture associated disease.
Animals
;
Bile Ducts
;
Cell Death
;
Cholangitis*
;
Constriction, Pathologic
;
Dogs
;
Epidermal Growth Factor
;
Epithelial Cells
;
Ethanol
;
Gallbladder
;
Humans
;
Immersion
;
Male
;
Microtubules
;
Nylons*
;
Paclitaxel
;
Phenobarbital
;
Rats*
;
Rats, Sprague-Dawley
8.Four Unrecorded Wood Decay Fungi from Seoul in Korea.
Yeongseon JANG ; Sung Wook LEE ; Seokyoon JANG ; Young Woon LIM ; Jin Sung LEE ; Jae Jin KIM
Mycobiology 2012;40(3):195-201
During the investigation of Korean indigenous fungi from Seoul, three genera-Fuscoporia, Porostereum, and Trametopsis, and four species-Fuscoporia senex, Phlebia acerina, Porostereum spadiceum, and Trametopsis cervina were found. Their morphological characteristics were examined and their identification was confirmed by molecular analysis based on internal transcribed spacer (ITS) and nuclear large subunit ribosomal DNA region sequences. These fungi are new to Korea and registered here with descriptions.
Basidiomycota
;
DNA, Ribosomal
;
Fungi
;
Korea
;
Wood
9.The Frequency Unexpected Antibodies at Kyungpook National University Hospital.
Jung Ran PARK ; Woon Bo HEO ; Sung Hwa PARK ; Kwan Suk PARK ; Jang Soo SUH
Korean Journal of Blood Transfusion 2007;18(2):97-104
BACKGROUND: Unexpected antibody screening and identification tests are very important pre-transfusion tests for preventing transfusion reactions. Nowadays, the column agglutination test is widely used in Korea. The results of many studies that used this method showed the decreased frequency of nonsignificant cold antibodies and an increased frequency of warm antibodies when compared with other studies that used the tube test or the microplate test. This study was performed in order to determine the accurate frequency and distribution of unexpected alloantibody by using the column agglutination test. METHODS: We analyzed the results from 32,218 antibody screening tests with using LISS/Coombs cards and ID-DiaCell I and II for the transfusion candidates and patients with hemolytic anemia who were seen at Kyungpook National University Hospital during a recent eight-year period. RESULTS: According to the results of the antibody screening test, 188 samples (0.58%) out of all 32,218 samples, were shown to be positive. Unexpected alloantibodies were detected in 86 patients (0.27%) with using the antibody identification test. The antibodies that were detected most frequently were anti-E (29 samples), followed by anti-D (8 samples), anti-M (8 samples) and anti-c (7 samples). CONCLUSION: The frequency and distribution of unexpected antibodies at our hospital are similar with those obtained in other Korean studies. The detection rates of warm antibodies, including Rh antibodies, were high. The proportion of Rh antibodies in patients with a gestation history was significantly higher than that in the patients without a gestation history. This study shows once again that pregnancy affects the antibodies and this supports the relationship between pregnancy and antibody formation.
Agglutination Tests
;
Anemia, Hemolytic
;
Antibodies*
;
Antibody Formation
;
Blood Group Incompatibility
;
Gyeongsangbuk-do*
;
Humans
;
Isoantibodies
;
Korea
;
Mass Screening
;
Pregnancy
10.Coverage of Donor Site Defect of Radial Forearm Free Flap by using Terudermis(R).
Jun Sung LEE ; Jong Wook LEE ; Jin Sik BURM ; Young Chul JANG ; Ji Woon HA
Journal of the Korean Society of Plastic and Reconstructive Surgeons 2001;28(4):357-361
Split-thickness skin grafting is commonly used to cover donor site defect of radial forearm free flap. One of disadvantages in this method is contour reflection of underlying structures (tendons and muscles) with irregularity which was caused by incomplete soft tissue replacement, and we called it 'silhouette phenomenon'. To promote soft tissue replacement, we have used Terudermis(R) (atelocollagen). In 10 cases of radial forearm free flap surgery of 10 patients, Terudermis(R) was applied on flap donor site just after flap surgery, followed by split-thickness skin grafting for resurfacing after 2 weeks. In all cases, Terudermis(R) and skin graft were taken well with no complications such as skin necrosis and loss. We successfully overcame silhouette phenomenon in all cases in the follow-up period of mean 8 months. Terudermis(R) , as a tissue-restoring biomaterial, is expected to be easily used for coverage of donor site defect of radial forearm free flap.
Follow-Up Studies
;
Forearm*
;
Free Tissue Flaps*
;
Humans
;
Necrosis
;
Skin
;
Skin Transplantation
;
Tissue Donors*
;
Transplants