No abstract available.
Congenital Hypothyroidism*

No abstract available.
Lipodystrophy, Congenital Generalized*

Takayasu's arteritis is an arterial inflammatory disease of unknown etiology, which most commonly affects the aorta and its large branches, and the pulmonary artery. This pathological condition which is prevalent in. Asian females results in occlusive changes in the lamina, often combined with dilation and secondary thrombus formation. It is associated with four main complications, which is Takayasu's retinopathy. secondary hypertension, aortic regurgitation and aortic or arterial aneurysms. The authors have experienced a case of Takayasu's arteritis (25 years old female) with severe retinopathy, complicated cataract. cyanotic engorged conjunctival vessels and new vessels as a collateral circulation in both eyes.
Aneurysm ; Aorta ; Aortic Valve Insufficiency ; Asian Continental Ancestry Group ; Cataract ; Collateral Circulation ; Female ; Humans ; Hypertension ; Pulmonary Artery ; Takayasu Arteritis* ; Thrombosis

There are 3 basic methods for surgical treatment of axillary osmidrosis; 1) method that removes only subcutaneous cellular tissue without removing skin 2) method that removes skin and subcutaneous cellular tissue en bloc, and 3) method that partially removes skin and subcutaneous cellular en bloc as well as removing the subcutaneous cellular tissue of the adjacent region. We studied the results of partial removal of the skin and subcutaneous cellular tissue en bloc, as well as the removal of subcutaneous cellular tissue of the adjacent region to compare the results of the bipedicled flap with the graft conversion method. There was no difference between two methods in results and complication rates. There are 3 advantage to this procedure. First, about 70-80% of apocrine glands were centrally distributed among the axillary hairbearing region therefore, resection of the central portion of axillary hair distribution area is important for good result. Second, the preservation of the subdermal plexus with careful excision of adjacent underlying subcutaneous tissue under the aid of the magnifying surgical loupe, is important for good wound healing. Third, the central excision of the axillary hair distribution area provides good exploration for undermining and defatting of the undersurface of the adjacent area, therefore it tooks a shorter operation time.
Apocrine Glands ; Hair ; Skin ; Subcutaneous Tissue ; Transplants ; Wound Healing

No abstract available.
Bandages* ; Gentian Violet* ; Gentiana* ; Methicillin-Resistant Staphylococcus aureus* ; Wounds and Injuries*

The maxillary alveolar ridge separates the palate from the lip and clefts of the primary palate have a cleft of the alveolus as well. In the most common clefts of the primary palate, the alveolar portion of the cleft is located between the lateral incisor, if present, and the canine. The cleft may also pass between the central incisor and the lateral incisor, rarer forms of clefts may pass between the central incisor or more distally on the maxillary arch. There are still considerable differences of opinion as to the optimal time for closure of alveolar defects, with or without concomitant bone grafting. But the preferred time for the operation with bone graft is between age 9 and 11 before the canine teeth have fully erupted. As an alternative to primary bone grafting, Skoog developed the periosteoplasty, or "boneless bone graft" technique, in which periosteal continuity was established between maxillary segments by the transfer of local periosteal flaps from the anterior maxillary wall. this procedure, which takes advantage of the propensity of periosteum to form bone in young children, leads to the formation of new bone within the alveolar cleft in spite of the fact that no bone graft is used.This study attempts to defin the effectiveness of early alveolar cleft repair with gingivo-vestibular-mucoperiosteal flap.The results in 6 unilateral alveolar clefts and 1 bilateral alveolar cleft, which is corrected early by gingivo-vestibular-mucoperiosteal flap, have been satisfactory alveolar arch continuity and alveolar bone formation with tooth eruption.
Alveolar Process ; Bone Transplantation ; Child ; Cuspid ; Humans ; Incisor ; Lip ; Osteogenesis ; Palate ; Periosteum ; Tooth Eruption ; Transplants

BACKGROUND: Methicillin-resistant Staphylococcus aureus (MRSA) is hardly controllable organism among the pathogen of nosocomial infection, because it is resistant to most antibiotics except vancomycin and local treatment with most antiseptics are not effective to eradicate MRSA from the infected wounds. There is increasing fear that MRSA infection can be spread widely in the hospitals. The effectiveness of Gentian Violet against MRSA was reported by Saji et al in 1992 for the first time. We tried Gentian Violet dressing on MRSA infected wounds to evaluate whether at not the Gentian Violet is effective to eradicate 11RSA which existed in the open wound. METHODS: 24 patients were treated by wet dressing with 0.1%Gentian Violet soaked gauze twice daily. They included 10 cases of sacral and trochanteric pressure sore, 6 cases of postoperative wound infectious, 3 cases of posttraumatic skin defects, 2 cases of DM foot, 1 case of post infectious skin defect and 2 cases of electrical burn, The wound culture was evaluated for elimination of MRSA infection twice weekly. RESULTS: The clinical results revealed that MRSA was not detected in all cases within 34days (average 13.5 days) after topical administration 0.1% Gentian Violet. CONCLUSION: There is no evidence of tissue irritation with Gentian Violet dressing on open wound or wound margin. After negative conversion of MRSA with Gentian Violet dressing, gram (-) organism was isolated in a half of the cases. 0.1% Gentian Violet topical administration is a useful treatment method of wound infection with MRSA.
Administration, Topical ; Anti-Bacterial Agents ; Anti-Infective Agents, Local ; Bandages* ; Burns ; Cross Infection ; Femur ; Foot ; Gentian Violet* ; Gentiana* ; Humans ; Methicillin-Resistant Staphylococcus aureus* ; Pressure Ulcer ; Skin ; Vancomycin ; Viola ; Wound Infection* ; Wounds and Injuries*

CD44 is a family of transmembrane glycoproteins involved in cell-cell and cell-matrix interactions. Expression of CD44 isofonns (splice variants) has been shown to be associated with poor prognosis in several human cancers. We evaluated the expression patterns of the CD44 isofortn (CD 44 splice variant v6) in infiltrating ductal carcinoma of the breast by immunohistochemical and RT-PCR method. Paraffin embedded blocks from seventy-five cases of mastectomized samples were analyzed immunohistochemically using monoclonoal antibody against CD44v6. CD44v6 was detected in fifty-seven cases (76%) of the tumor samples. Adjacent normal myoepithelial cells and ductal epithelial cells revealed focal positive reaction to CD44v6. Thirtytwo cases (80.0%) with lymph nodal metastasis revealed overexpression of CD44v6 monoclonal antibody, but twenty-five cases (71.4%) without nodal metastasis also showed positive reaction to CD44v6 monoclonal antibody, and there is no statistically significant value. Other prognostic factors of infiltrating ductal carcinoma, such as tumor size, histologic grade and hormonal receptors did not show any significant correlation with CD44v6 expression. The RT-PCR studies for 9 cases of infiltrating ductal carcinoma showed the same band patterns both in the normal and tumor tissues. From the above results, it is concluded that the expression of CD44v6 is not a valuable prognostic marker of infiltrating ductal carcinoma of breast.
Breast* ; Carcinoma, Ductal* ; Epithelial Cells ; Glycoproteins ; Humans ; Neoplasm Metastasis ; Paraffin ; Prognosis

No abstract available.
Ascites* ; Cystic Adenomatoid Malformation of Lung, Congenital*

The following results were obtained through the screening survey to detect the prevalence of hematuria & proteinuria in the healthy Korean schoolchildren. A total of 2,888 primary schoolchildren in Seoul, examined to be healthy by the author were tested for hematuria and proteinuria during the period of 3 months from Apr. 1979 to June 1979. Hemacombistix of Ames Company, U.S.A. was used in this examination. 1. The prevalence of hematuria detected with Hema-combistix was 1.97%(57 children) and that of microscopic hematrua was 0.93% (27 children). The prevalence of proteinuria was noted in 2.04%(59 children). 2. The prevalence of hematuria detected with Hema-combistix was higher in female children as 2.66% among 1,355 children, compared to 1.37% among 1,533 male children, which was ore prominent in the age 9 year-old group. The prevalence in female was higher than in male in all but 7 year-old age group. 3. The prevalence of microscopic hematuria was higher in female children as 1.40% compared to 0.52% in male. The prevalence was higher in female children in all but 7 year-old age group. 4. The correlation of tests of hematuria between Hema-combistix and microscopcy showed 85.2% in sensitivity and 59.0% in specificity. And there showed a statistically significant difference in the prevalence rates detected as above one positive in the both tests. 5. The prevalence of proteinuria was higher in female children as 2.8%, compared to 1.37% in male, which was more prominent in the 11 year-old age group. The age prevalence of proteinuria showed increasing frequency as age increases. The highest age prevalence was 1.94% in 12 year-old age group among males and 4.91% in 11 year-old age group among females. 6. The prevalence of co-existence of microscopic hematuria and proteinuria was 0.07%, which was noted in 2 cases in each 8 year and 10 year-old group. 7. Microscopic hematuria was present mostly in the range of one positive(5-20 RBC/HPF), which was prominent in female children. However, hematuria detected as above three positive (above 40 RBC/HPF) was found in male children. 8. Proteinuria was noted mostly in the range of one positive(30mg/dl) and the prevalence of proteinuria above 100mg/dl was 9.52% in males & 13.16% in females. And proteinuria above 300 mg/dl was noted in one male child.
Child* ; Female ; Hematuria* ; Humans ; Male ; Mass Screening ; Prevalence ; Proteinuria* ; Sensitivity and Specificity ; Seoul