1.The clinical and histopathological studies on ovarian tumors.
Sung woon CHANG ; Seon Kyung LEE ; Seoung Bo KIM ; Jae Hyun LEE ; Jung Eun MOK
Korean Journal of Obstetrics and Gynecology 1993;36(7):1073-1083
No abstract available.
2.Production of extracellular enzymes and histamine release from rat peritoneal mast cells by aeromonas hydrophila.
Seok Don PARK ; Jung Woon KO ; Byung Deuk JEON ; Seon Hee OH ; Chang Ho SONG ; Myoung Ok KOH
Korean Journal of Dermatology 1991;29(6):745-758
No abstract available.
Aeromonas hydrophila*
;
Aeromonas*
;
Animals
;
Histamine Release*
;
Histamine*
;
Mast Cells*
;
Rats*
3.Nurses' Job Analysis in a Regional Emergency Center Using the DACUM
Hee Je YUN ; Eun Hee JUNG ; Woon Seon JUNG ; Sang Rim LEE ; Young Ok KWON
Journal of Korean Clinical Nursing Research 2020;26(1):26-46
Purpose:
This study aimed to establish the role of and to analyze the job of nurses in a regional emergency center using the Developing a Curriculum(DACUM) process, a job analysis technique.
Methods:
The DACUM committee was organized, and three workshops were held from June 1st to July 4th, 2016. One hundred two nurses in a regional emergency center participated in a survey from October 3rd to 10th, 2016. The frequency, importance and difficulty of each tasks and task elements in the DACUM were investigated on a Likert scale.
Results:
The roles of nurses in a regional emergency center were identified and the DACUM chart was developed with 6 duties, 29 tasks and 153 task elements. According to the survey, some tasks such as ‘CPR,’ ‘acute respiratory distress care,’ and ‘drug administration’ showed high frequency and importance or difficulty in all nursing units in common, and different results reflected the characteristics of each nursing unit were also found.
Conclusion
The results showed the feature of the regional emergency center. Based on these results, it is necessary to develop educational programs for practice.
4.Verruca Vulgaris on Top of a Melanocytic Nevus Simulating Melanoma.
Young Woon PARK ; So Young YOON ; Seung Hwan PAIK ; Eun Jung HWANG ; Seon Pil JIN ; Hyun Sun PARK ; Hyun Sun YOON ; Soyun CHO
Korean Journal of Dermatology 2012;50(10):923-924
No abstract available.
Melanoma
;
Nevus
;
Nevus, Pigmented
;
Warts
5.Clinical Guidelines for the Diagnosis and Treatment of Cushing's Disease in Korea.
Kyu Yeon HUR ; Jung Hee KIM ; Byung Joon KIM ; Min Seon KIM ; Eun Jig LEE ; Sung Woon KIM
Endocrinology and Metabolism 2015;30(1):7-18
Cushing's disease (CD) is a rare disorder characterized by the overproduction of adrenocorticotropic hormone due to a pituitary adenoma that ultimately stimulates excessive cortisol secretion from the adrenal glands. Prior to the detection of pituitary adenomas, various clinical signs of CD such as central obesity, moon face, hirsutism, and facial plethora are usually already present. Uncontrolled hypercortisolism is associated with metabolic, cardiovascular, and psychological disorders that result in increased mortality. Hence, the early detection and treatment of CD are not only important but mandatory. Because its clinical manifestations vary from patient to patient and are common in other obesity-related conditions, the precise diagnosis of CD can be problematic. Thus, the present set of guidelines was compiled by Korean experts in this field to assist clinicians with the screening, diagnoses, and treatment of patients with CD using currently available tests and treatment modalities.
Adrenal Glands
;
Adrenocorticotropic Hormone
;
Corticotropin-Releasing Hormone
;
Cushing Syndrome
;
Diagnosis*
;
Hirsutism
;
Humans
;
Hydrocortisone
;
Korea
;
Mass Screening
;
Mortality
;
Obesity, Abdominal
;
Petrosal Sinus Sampling
;
Pituitary ACTH Hypersecretion
;
Pituitary Neoplasms
6.A case of combined adrenocorticotropic hormone(ACTH) and growth hormone(GH) deficiency.
Hyung Seon RYEU ; Seung Sig SIM ; Mann JUNG ; Chang Hyun PARK ; Chan Woong PARK ; Young Mi LEE ; Seok Bae CHEON ; Sang Ku KANG ; Yong MOON ; Ji Woon KIM
Korean Journal of Medicine 1993;45(4):522-526
No abstract available.
7.Amiodarone Induced Toxic Hepatitis: A case report.
Seon Jung KIM ; Bon Wook KOO ; Jin Ho BAE ; Seung Woon LIM
Korean Journal of Anesthesiology 2007;53(4):528-531
Although amiodarone is a widely used and effective long-term antiarrhythmic drug, it is known to have life-threatening adverse effects, including acute hepatotoxicity. Although the occurrence of acute hepatotoxicity after amiodarone administration is rare, it can be fatal. However, this phenomenon has not been well studied. Here, we describe a 39 year old woman with atrial fibrillation and supraventricular tachycardia who developed acute toxic hepatitis within 8 days of amiodarone administration at the recommended dosage. The drug was withdrawn and the laboratory findings progressively returned to normal.
Adult
;
Amiodarone*
;
Arrhythmias, Cardiac
;
Atrial Fibrillation
;
Drug-Induced Liver Injury*
;
Female
;
Humans
;
Tachycardia, Supraventricular
8.The Effect of Premedication using a Jet-injector in Pediatric Patients.
Geon KIM ; Hyo Seok NA ; Seon Jung KIM ; Seung Woon LIM ; Jin Ho BAE
Korean Journal of Anesthesiology 2007;53(3):291-297
BACKGROUND: This study was designed to evaluate the efficacy and safety of midazolam premedication administered by a jet-injector in pediatric patients. METHODS: Children undergoing outpatient surgery were randomized into three groups: intravenous induction with thiopental sodium (control group, n = 20), oral midazolam premedication (PO-med group, n = 20) or midazolam premedication using a jet-injector (Jet-med group, n = 20). In the PO-med and Jet-med group patients, anesthetic induction was performed by sevoflurane inhalation and an intravenous catheter (IVC) was inserted after the children had been anesthetized by sevoflurane inhalation. For the control group patients, an IVC was placed in the preoperative holding area. Agitation scores were recorded in the preoperative holding area and recovery room. Anesthesia times and the views of the medical staff concerning the technique benefits were also noted. Patients and parents were interviewed on the following day. RESULTS: Maximum agitation scores in the preoperative holding area and during separation with parents were significantly lower in the PO-med and Jet-med groups. The induction time was significantly longer in the PO-med and Jet-med groups. No statistically significant differences were found for the recovery characteristics. Though interviews with patients and parents produced similar results for patients in each group, the medical staff satisfaction levels were significantly higher for patients in the PO-med and Jet-med groups. CONCLUSIONS: The findings of this study suggest that the application of the jet-injector for midazolam premedication may be clinically useful in children who do not have an IVC. The use of the jet-injector could be a substitute for the oral route for midazolam administration.
Ambulatory Surgical Procedures
;
Anesthesia
;
Catheters
;
Child
;
Dihydroergotamine
;
Humans
;
Inhalation
;
Medical Staff
;
Midazolam
;
Parents
;
Preanesthetic Medication
;
Premedication*
;
Recovery Room
;
Thiopental
9.Prediction of the Clinical Course According to the Macroscopic Type by Colonoscopy in Behcet's Colitis.
In Sung SONG ; Chung Yong KIM ; Hyun Chae JUNG ; Dong Ho LEE ; Kyu Wan CHOI ; Seon Hee LIM ; Sun Mi KIM ; Dong Young PARK ; Byung Kwan KIM ; Woon Tae JUNG ; Cheol Joo HAN
Korean Journal of Gastrointestinal Endoscopy 1996;16(1):30-39
The intestinal lesion of Behcet's colitis shows aphthoid or punched-out ulceration. But these morphological characteristics are variable and the clinical course of Behcet's colitis is also diverse. There have been many case reports since 1962, but there is few study for clinical course or for morphological characteristics of intestinal lesion of Behcet's colitis. So we retrospectively investigated the clinical course of Behcet's colitis according to colonoscopic findings. Thirty-two patients with Behcet's colitis were investigated retrospectively from January 1984 to July l994. The patients who had at least two major stigmata of Behcet's syndrome with intestinal lesions were included, and whose colonoscopic films were available and whose follow-up studies were done. The studies used at their follow-up were colonoscopy and/or barium enema. In our study the patients ranged in age from 15 to 64 years old, with mean age of 37 years old; 28% were in 3rd decade. The mean follow-up period was 33 months.
Adult
;
Barium
;
Behcet Syndrome
;
Christianity
;
Colitis*
;
Colonoscopy*
;
Enema
;
Follow-Up Studies
;
Humans
;
Middle Aged
;
Retrospective Studies
;
Stomatitis, Aphthous
;
Ulcer
10.Platinum nanoparticles reduce ovariectomy-induced bone loss by decreasing osteoclastogenesis.
Woon Ki KIM ; Jin Chun KIM ; Hyun Jung PARK ; Ok Joo SUL ; Mi Hyun LEE ; Ji Soon KIM ; Hye Seon CHOI
Experimental & Molecular Medicine 2012;44(7):432-439
Platinum nanoparticles (PtNP) exhibit remarkable antioxidant activity. There is growing evidence concerning a positive relationship between oxidative stress and bone loss, suggesting that PtNP could protect against bone loss by modulating oxidative stress. Intragastric administration of PtNP reduced ovariectomy (OVX)-induced bone loss with a decreased level of activity and number of osteoclast (OC) in vivo. PtNP inhibited OC formation by impairing the receptor activator of nuclear factor-kappaB ligand (RANKL) signaling. This impairment was due to a decreased activation of nuclear factor-kappaB and a reduced level of nuclear factor in activated T-cells, cytoplasmic 1 (NFAT2). PtNP lowered RANKL-induced long lasting reactive oxygen species as well as intracellular concentrations of Ca2+ oscillation. Our data clearly highlight the potential of PtNP for the amelioration of bone loss after estrogen deficiency by attenuated OC formation.
Animals
;
Metal Nanoparticles/*administration & dosage
;
Mice
;
Mice, Inbred C57BL
;
NFATC Transcription Factors/metabolism
;
*Osteoclasts/drug effects/physiology
;
Osteoporosis/drug therapy
;
Ovariectomy/adverse effects
;
Oxidative Stress/drug effects
;
Platinum/*administration & dosage
;
*RANK Ligand/genetics/metabolism
;
Reactive Oxygen Species/metabolism
;
Signal Transduction