No abstract available.
Reference Values*

No abstract available.
Aspergillosis ; Diabetes Mellitus ; Humans ; Liver Cirrhosis ; Liver ; Lung ; Maxillary Sinus

No abstract available.
Intracranial Arteriovenous Malformations* ; Microsurgery*

An adequate supply of dietary iodine is essential for the synthesis of the thyroid hormons. The measurement of dietary iodine intake is important for the clinical assessment of thyroid disease, especially in areas where iodine intake is excessive or deficient.To evaluate dietary iodine intake in Korean and its effects on thyroid function, we measured urinary iodine excretion with morning urine by electrode method in 184 normal subjects, 96 postpartum women and 181 patients with thyroid disease from October 1994 to February 1995. The results were as follows;1) In normal control, the mean value of urinary iodine excretion was 3.8+-2.7mg/L (range 0.1-15.0mg/L). However, there was no sex and age differences in the urinary iodine excretion.2) In postpartum women, the urinary iodine excretion was 9.0+-10.8mg/L who were not taken high iodine diet(Miyok-Guk), the mean value was statistically higher than normal control(p<0.01) and significant increased the urinary iodine excretion after eating of high iodine diet(p<0.01).3) In volunteer, there were increase of urinary iodine excretion more than 10 folds after high iodine diet and medication.4) The urinary iodine excretion in patients with thyroid diseases was not different from normal control, and there were no significant differences of urinary iodine excretion among the patient groups. The urinary iodine excretion in the acute stage of patients with subactue thyroiditis or painless thyroiditis was significantly increased compared to the recovery stage. However, it was not significantly different from that of normal control.In conclusion, urinary iodine excretion in Korean population is very high comparing to the reported data in Western population but similar with Japanese. The urinary iodine excretion is significant increase( more than 10-folds of basal level) after high iodine diet or high iodine containing medication in postpartum women or healthy persons. As a clue of destruction induced thyrotoxicosis, the urinary iodine excretion measurement is not valid in area where iodine intake is excessive like Korea.
Asian Continental Ancestry Group ; Diet ; Eating ; Electrodes ; Humans ; Iodine ; Korea ; Methods ; Postpartum Period ; Thyroid Diseases ; Thyroid Gland ; Thyroiditis ; Thyrotoxicosis ; Volunteers

Osteochondroma is a benign bone tumor that is most commonly found in the extremities and is prevalent in adolescents, with a peak incidence before the age of 20 years. Herein, we present a rare case of a 33-year-old man with an asymptomatic tumor on the right anterior rib that was pathologically confirmed to be a rib osteochondroma after surgical excision. We describe the computed tomography and magnetic resonance imaging (MRI) procedures and highlight the importance of MRI as a critical diagnostic tool for osteochondroma.

Prediction of individual outcome after cardiopulmonary resuscitation is of major medical, ethical, and socioeconomic interest but uncertain. We experienced the case thats the patient got complete neurologic recovery after the 123th day firm cardiac arrest, who had been suspected to go with poor prognosis because she got the findings of Glasgow Coma Scale 4, severe diffuse encephalopathy on encephalogram and generalized tonic-clonic seizure at the 4th day. Recently, a 29 year-old women who sustained from respiratory arrest induced presumably by sedative and anticonvulsant therapy for control of seizure that happened during local lidocaine anesthesia far mamoplasty was transfered to our emergency medical center from local private plastic office. Arrest time was about 20 minutes. On hospital arrival, she had a pulseless bradyasystole and no respiration, but spontaneous circulation was restored at 10 minutes artier CPR started. We started cerebral oriented resuscitation including mild hypothermia(34degrees C), hemodilution, calcium channel blocker infusion. On hospital day 4, patient's glasgow coma scale(GCS) was 4. On hospital clay 7, Brain Magnetic Resonance Imaging(MRI) showed high signal intensity on T2WI, involving the bilateral basal ganglia. After contrast administraton, marked enhancement can be seen at the lesion site. Patient's glasgow coma scale(GCS) increased step by step to 5 on 8th day, 7 on 14th day, 10 on 15th day, 13 on 17th day, 15 on 20th day. 40 days later the patient was discharged with minor neurologic abnormality including hand tremor, dysphonia, amenorrhea and Mini Mental State Examination(MMSE) score(26). Long-term Follow up revealed that all neurologic functional abnormality inducting hand tremor, dysphonia, amenorrhea and MMSE score(26) is completely recovered on 123th day after episode of cardiopulmonary arrest.
Adult ; Amenorrhea ; Anesthesia ; Basal Ganglia ; Brain ; Calcium Channels ; Cardiopulmonary Resuscitation ; Coma ; Dysphonia ; Emergencies ; Female ; Follow-Up Studies ; Glasgow Coma Scale ; Hand ; Heart Arrest* ; Hemodilution ; Humans ; Hypoxia-Ischemia, Brain* ; Lidocaine ; Plastics ; Prognosis ; Respiration ; Resuscitation ; Seizures ; Tremor

The human organic anion transporter 4 (hOAT4) has been identified as the fourth isoform of OAT family. hOAT4 contributes to move several negatively charged organic compounds between cells and their extracellular milieu. The functional characteristics and regulatory mechanisms of hOAT4 remain to be elucidated. It is well known that caveolin plays a role in modulating proteins having some biological functions. To address this issue, we investigated the co-localization and interaction between hOAT4 and caveolin-1. hOAT4 and caveolin-1 (mRNA and protein expression) were observed in cultured human placental trophoblasts isolated from placenta. The confocal microscopy of immuno-cytochemistry using primary cultured human trophoblasts showed hOAT4 and caveolin-1 were co-localized at the plasma membrane of the cell. This finding was confirmed by Western blot analysis using isolated caveolae-enriched membrane fractions and immune-precipitates from the trophoblasts. When synthesized cRNA of hOAT4 along with scrambled- or antisense-oligodeoxynucleotide (ODN) of Xenopus caveolin-1 were co-injected to Xenopus oocytes, the [3H]estrone sulfate uptake was significantly decreased by the co-injection of antisense ODN but not by scrambled ODN. These findings suggest that hOAT4 and caveolin-1 share a cellular expression in the plasma membrane and caveolin-1 up-regulates the organic anionic compound uptake by hOAT4 under the normal physiological condition.
Animals ; Caveolin 1/genetics/*metabolism ; Cells, Cultured ; Female ; Humans ; Immunohistochemistry ; Immunoprecipitation ; Microscopy, Confocal ; Models, Biological ; Oocytes/metabolism ; Organic Anion Transporters/genetics/*metabolism ; Placenta/cytology ; Protein Binding ; Reverse Transcriptase Polymerase Chain Reaction ; Trophoblasts/cytology/*metabolism ; Xenopus

Neurilemmoma (Schwannoma) is a extremely rare benign tumor which origin is thought to be of nerve sheath of peripheral, cranial and sympathetic nerve. Here we report a case of orbital neurilemmoma which has grown more than two years in the female patient of thirty years old. She visited to our hospital because of decreased visual acuity and protrusion of the right eyeball. Surgery of the orbit revealed a wall-nut sized, well encapsulated, gray colored, egg-shaped tumor which was confirmed by biopsy.
Biopsy ; Female ; Humans ; Neurilemmoma* ; Orbit* ; Visual Acuity

PURPOSE: To determine the effect of cataract extraction on visual field damage in glaucoma patients with cataracts. METHODS: Sixty-two eyes of fifty glaucoma patients (primary open-angle glaucoma, angle-closure glaucoma, and normal-tension glaucoma) were divided into three groups according to the MD (mean deviation) value from the Humphrey automatic visual field test. The PSD (pattern standard deviation) values were analyzed before and after the cataract surgery. Additionally, the visual acuity, intraocular pressure and the number of antiglaucomatous agents were compared. RESULTS: All of the three groups, showed significant improvement in visual acuity. However, there was only a significant decrease in intraocular pressure at three months postoperatively. When comparing the mean MD values of each group, there was a statistically significant difference between the mild defect group and the severe defect group, but no statistically significant difference in the moderate defect group. There was also no statistically significant difference in PSD values in the any of the groups before and after cataract surgeries. CONCLUSIONS: In glaucoma patients with cataracts, there were no significant differences in PSD values before and after cataract surgery. Additionally, to perform an adequate cataract operation in advanced glaucoma patients without the progression of visual field damage, lowering intraocular pressure and improving visual acuity is helpful.
Cataract ; Cataract Extraction ; Eye ; Glaucoma ; Glaucoma, Angle-Closure ; Glaucoma, Open-Angle ; Humans ; Intraocular Pressure ; Visual Acuity ; Visual Field Tests ; Visual Fields

Regardless of an appropriate radiation therapy administered to a patient with a brain tumor, clinical and radiological evidence of progression may still develop because of a recurrence of the tumor and/or radiation necrosis, or even rarely, a radiation induced neoplasm. The evaluation of tumor recurrence and radiation-induced necrosis presents a diagnostic challenge. A thirty eight year old woman was treated for a focal motor seizure on the right side of her face.with a fractionated external beam radiotherapy under the impression of cystic astrocytoma in the left frontoparietal region. After 6 months, she developed a headache, nausea and vomiting, dysphagia, and secondary generalized seizure. A follow-up brain MRI showed a high signal mass lesion in a T2 weighted image and a fluorodeoxyglucose PET revealed hypometabolism in the left frontoparietal lobe, suggesting radionecrosis. It was confirmed as radionecrosis with an expanding edema by open biopsy. We report a cerebral radiation necrosis mimicking recurrent brain tumor.
Astrocytoma ; Biopsy ; Brain ; Brain Neoplasms* ; Deglutition Disorders ; Edema ; Female ; Follow-Up Studies ; Headache ; Humans ; Magnetic Resonance Imaging ; Nausea ; Necrosis* ; Radiotherapy ; Recurrence ; Seizures ; Vomiting