Descending necrotizing mediastinitis (DNM) is one of the most lethal form of mediastinitis originating from an oropharyngeal infection. It requires an early and aggressive sugical treatment, but the operative approach and optimal form of mediastinal drainage remains controversial. We report a case of DNM in a 45-year-old male who underwent right cervicomediastinotomy to drain the deep neck space, upper mediastinum and anterior mediastinal drainage was accomplished through a subxiphoid approach. After this procedure, he steadily improved and was dischrged on hospital day 36. We report this case with a brief review of the literature.
Drainage ; Humans ; Male ; Mediastinitis* ; Mediastinum ; Middle Aged ; Neck

No abstract available.

No abstract available.
DiGeorge Syndrome*

No abstract available.
Aprotinin* ; Heart* ; Hemostasis* ; Thoracic Surgery*

No abstract available.
Heart* ; Thoracic Surgery* ; Thyroid Gland*

No abstract available.
Humans ; Infant, Newborn* ; Rhabdomyoma*

No abstract available.
Humans ; Immunoglobulin G* ; Immunoglobulins* ; Pneumonia*

The purpose of this study was to examine the mRNA levels of TNF-alpha and IL-6 in the cell lines of normal oral keratocyte and oral squamous cell carcinoma. Total RNA was extracted from these cell lines, observed under UV light, developed by radiographic films of PCR products via reverse transcriptase polymerase chain reaction (RT-PCR) amplication, and measured with densitometer. Each mRNA level of these cell lines divided by beta-actin mRNA level was compared to that of normal control group. The results were as follows : 1. Higher mRNA expression of TNF-alpha than IL-6 in the normal oral epithelial cell line. 2. In general, expression of mRNA of IL-6 appeared 3-4 times more in tumor cell lines than in control group. 3. mRNA expression of TNF-alpha showed variable expression in tumor cell lines, unlike normal cell line. 4. There are no special connections between differentiation of oral cancer cell lines and mRNA expression of TNF-alpha and IL-6. From the above results, expression of mRNA of IL-6 in the cell lines of squamous cell carcinoma used in this study has higher than the normal oral epithelial cell line, but there are no relationship between the differentiation of oral cancer cell lines and the expression of mRNA of TNF-alpha and IL-6.
Actins ; Carcinoma, Squamous Cell* ; Cell Line* ; Cell Line, Tumor ; Epithelial Cells ; Interleukin-6* ; Mouth Neoplasms ; Polymerase Chain Reaction ; Reverse Transcriptase Polymerase Chain Reaction ; RNA ; RNA, Messenger* ; Tumor Necrosis Factor-alpha* ; Ultraviolet Rays ; X-Ray Film

No abstract available.
Humans ; Lung Neoplasms* ; Lung*

A case of primary malignant fibrous histiocytoma(MFH) of the lung occurring in a 62-year-old man is presented. After preoperative bronchial brushing and washing cytologic diagnosis of poorly differentiated carcinoma, surgical resection and lymph nodes dissection were performed. Subsequent histologic examination revealed a primary MFH. The diagnosis was confirmed by electron microscopic and immunohistochemical examinations. The review of the bronchial brushing and washing cytologic features disclosed many bipolar and a few unipolar spindle tumor cells with a "comet" configuration, mainly single cells, but also forming loose clusters. The nuclei were elongated and hyperchromatic and contained one or more irregular nucleoli. Scattered bizarre, multinucleated tumor giant cells were also present.
Diagnosis ; Giant Cells ; Histiocytoma, Malignant Fibrous* ; Humans ; Lung* ; Lymph Nodes ; Middle Aged