1.Eosinophilic Myocarditis Associated with Hypereosinophilia.
Jin Sook RYU ; In Whan SEONG ; Jae Joong KIM ; Eun Sil YU ; Seong Wook PARK ; Seung Jung PARK ; Jong Koo LEE
Korean Circulation Journal 1991;21(3):626-632
A variety of disease states are marked by prolonged and profound eosinophilia associated with localized or widespread eosinophilic infiltrates. Cardiac involvement maybe a major cause of morbidity and mortality of this disease. We report a case of acute peri-myocarditis with eosinophilia, which was confirmed as eosinophilic myocardilic myocarditis by endomyocardial biopsy.
Biopsy
;
Eosinophilia
;
Eosinophils*
;
Mortality
;
Myocarditis*
2.The Effect of Wrist Position on the Conduction Velocity of the Ulnar Nerve.
Min Wook KIM ; Young Jin KO ; Seong Hoon LIM
Journal of the Korean Academy of Rehabilitation Medicine 2003;27(5):708-711
OBJECTIVE: The purpose of this study was to investigate the effect of wrist position on the ulnar nerve conduction velocity. METHOD: Ulnar motor nerve conduction studies were performed bilaterally in twenty healthy adult volunteers. For each limb, nerve conduction study was carried out in two different positions. In the first position, shoulder were abducted, elbow and wrist flexed to 90o. For the second position, all joints were kept constant except for the wrist where it was extended. Routine conduction study was performed in both wrist positions. All data were statistically analyzed. RESULTS: The average conduction velocities in the wrist flexed position were 61.6 m/sec for the forearm segment and 62.3 m/sec across elbow. With the wrist extended, the average was 62.6 m/sec and 64.1 m/sec, respectively. The differences in conduction velocities between two different wrist positions were statistically significant (p<0.05). In the wrist flexed position, the average measured latencies were 2.3 msec with wrist, 5.4 msec below elbow, and 7.4 msec above elbow stimulation, compared to wrist extended which showed 2.4, 5.4 and 7.2 msec, respectively. The difference of latencies at wrist between the two wrist positions was statistically significant (p<0.05). CONCLUSION: The authors conclude that wrist position affect ulnar nerve conduction velocity.
Adult
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Elbow
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Extremities
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Forearm
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Humans
;
Joints
;
Neural Conduction
;
Shoulder
;
Ulnar Nerve*
;
Volunteers
;
Wrist*
3.Hypophosphatemic Rickets.
Kyung Mo KIM ; Seong Hoon HA ; Dong Kyu JIN ; Kwang Wook KO
Journal of the Korean Pediatric Society 1990;33(4):437-447
No abstract available.
Rickets, Hypophosphatemic*
4.Epidemiological Characteristics of Field Tick-Borne Pathogens in Gwang-ju Metropolitan Area, South Korea, from 2014 to 2018
Jung Wook PARK ; Seung Hun LEE ; Gi Seong LEE ; Jin Jong SEO ; Jae Keun CHUNG
Osong Public Health and Research Perspectives 2020;11(4):177-184
The importance of tick-borne diseases is increasing because of climate change, with a lack of long-term studies on tick-borne pathogens in South Korea. To understand the epidemiological characteristics of tick-borne diseases, the monthly distribution of field ticks throughout the year was studied in South Korea between May 2014 and April 2018 in a cross sectional study. The presence of various tick-borne pathogens ( During the study period there were 11,717 ticks collected and 4 species identified. In conclusion, due attention should be paid to preventing tick-borne infections in humans whilst engaged in outdoor activities in Spring and Autumn, particularly in places where there is a high prevalence of ticks.
8.Risk factors of delirium in elderly inpatients.
Seong Wook HWANG ; Seong Wook KANG ; Young Gon KANG ; Seung Gon CHOI ; Jin LEE ; Moon Jong KIM ; Young Jin LEE ; Chul Young BAE
Journal of the Korean Academy of Family Medicine 2002;23(1):112-121
BACKGROUND: This study was done to investigate the clinical risk factors of delirium in general hospital's elderly inpatients. METHODS: A case-control study design was used. Forty cases and age -sex matched 120 contols were identified using hospital discharge data from June 1995 to May 2001. The controls were selected during the same period. The clinical records of each subject were reviewed using discharged disease code to select cases. Subsequent7, the data were recorded from clinical records. RESULTS: The subjects admitted with delirium tended to have increased age (P=0.007), hypoxia(P=0.018), low hemoglobin(P =0.011),sleep disturbance (P=0.001), more ADL total dependence ( P=0.018), diagnoses with infections (P=0.006), diabetes (P=0.046), and hypertension (P=0.041). Above risk factors seemed to be clinically associated with delirium. CONSLUSION: These findings indicate that rapid infection control, maintenance of good sleep hygiene, well-controlled diabetes and hypertension, and correction of hypoxia may help to prevent delirium in general hospital's elderly inpatients.
Activities of Daily Living
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Aged*
;
Anoxia
;
Case-Control Studies
;
Delirium*
;
Diagnosis
;
Humans
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Hygiene
;
Hypertension
;
Infection Control
;
Inpatients*
;
Risk Factors*
9.Expression of Vascular Endothelial Growth Factor in Hepatocellular Carcinomas.
Seong Woo HONG ; Hee Jung WANG ; Yun Mi JIN ; Wook Hwan KIM ; Eu Young SO ; Myung Wook KIM
Journal of the Korean Surgical Society 1999;57(1):81-85
BACKGROUND: A tumor must continuously stimulate the growth of new capillary blood vessels for the tumor itself to grow and metastasize. Vascular endothelial growth factor (VEGF) promotes vascular permeability and endothelial cell growth. A hepatocellular carcinoma (HCC) is a typical hypervascular tumor. METHODS: We evaluated the expression of VEGF in 36 cases of HCC by using immunohistochemical staining in order to define its prognostic value. RESULTS: The expression rate of VEGF was 44.4% (16/36) in tumor cells and 0% (0/36) in non- tumorous liver parenchyme. VEGF expression did not correlate with any clinicopathological characteristics. And patients with expression of VEGF in tumor cells had no survival difference in comparison to those without VEGF expression. CONCLUSIONS: These results suggest that the expression of VEGF in HCC cells by itself may not be a significant factor in the prognosis of HCC.
Blood Vessels
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Capillaries
;
Capillary Permeability
;
Carcinoma, Hepatocellular*
;
Endothelial Cells
;
Humans
;
Liver
;
Prognosis
;
Vascular Endothelial Growth Factor A*
10.Clinical Implications of VEGF and p53 Expression in Squamous Cell Carcinoma of the Cervix Treated with Radiation Therapy.
Jin Oh KANG ; Seong Eon HONG ; Dong Wook KANG
Cancer Research and Treatment 2003;35(5):440-444
PURPOSE: The present study was designed to analyze the relationship between vascular endothelial growth factor (VEGF) and p53, and their impact on clinical outcome in squamous cell carcinoma of the cervix treated with radiation therapy. MATERIALS AND METHODS: This immunohistochemical study involved 23 patients with available paraffin blocks among 46 patients who were treated during the period from 1994 to 1997 in Eulji University Hospital in Korea. Anti-VEGF mouse monoclonal antibody and DO-7 anti- p53 mouse monoclonal antibody were used as the primary antibodies. Antibody binding was detected with a LSAB kit. Staining was defined as positive for VEGF and p53, when more than 10% and 5% of the tumor cells were stained out of 500 cells counted, respectively. RESULTS: FIGO stage (p=0.05) and tumor size (p=0.04) were significant prognostic factors for survival. p53 expression was present in 17 (77%) cases. There was no significant relationship between p53 staining and the clinicopathologic factors, such as FIGO stage (p=0.98), tumor size (p=0.43), lymph node status (p=0.82), parametrial invasion (p=0.96), and age (p=0.18). The five year survival rates according to the p53 expression status were 80% for the p53 negative group and 66% for the p53 positive group (p=0.58). Positive VEGF expression was observed in 11 (47%) of the total of 23 patients. Statistical evaluation of VEGF expression according to stage (p=0.36), tumor size(p=0.11), lymph node status (p=0.82), parametrial invasion (p=0.49), and age (p=0.55) revealed no significant difference in any of these parameters. The five year survival rates according to the VEGF expression status were 89% for the VEGF negative group and 41% for the VEGF positive group (p=0.07). CONCLUSION: We suggest that VEGF expression may have an effect on the prognosis of cervix cancer patients treated with radiation therapy, and further evaluation with a large sample size is warranted.
Animals
;
Antibodies
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Carcinoma, Squamous Cell*
;
Cervix Uteri*
;
Female
;
Humans
;
Korea
;
Lymph Nodes
;
Mice
;
Paraffin
;
Prognosis
;
Radiotherapy
;
Sample Size
;
Survival Rate
;
Uterine Cervical Neoplasms
;
Vascular Endothelial Growth Factor A*