Although basal cell carcinoma is the most common skin cancer, it rarely metastasizes. Metastatic basal cell carcinoma may, therefore, initially elude diagnosis and management. We describe the case of a patient with a metastatic basal cell carcinoma present in the lungs. The differential diagnosis of suspected metastatic lesions should include metastases from a cutaneous basal cell carcinoma, in addition to those from more commonly metastasizing carcinomas, especially in patients with a history of a large basal cell carcinoma that has involved the head and neck regions, and was refractory to treatment.
Carcinoma, Basal Cell ; Diagnosis, Differential ; Head ; Humans ; Lung ; Neck ; Neoplasm Metastasis ; Skin Neoplasms

BACKGROUND: Spa therapy is widely used in many countries for the treatment of atopic dermatitis. There have been some reports about the therapeutic efficacies and mechanisms of spa therapy for the treatment of atopic dermatitis (AD) from other countries, but there have been no such reports from Korea. OBJECTIVE: The purpose of this study was to investigate the therapeutic efficacy and the safety of Hae-Un-Dae spa therapy for adult AD patients. METHODS: A total of 15 patients with AD were recruited in this study. The patients were classified into the mild group (n=5) and severe group (n=10) according to their eczema area and severity index (EASI) score at baseline. They had a bath in a Hae-Un-Dae spa three times per week for 4 weeks. To evaluate the therapeutic efficacy, the EASI score, the physician's global assessment (PGA) and the visual analogue scale (VAS) for pruritus were assessed every week. The skin hydration, the skin pH and the transepidermal water loss (TEWL) were also measured weekly to investigate the changes of the skin barrier function during the spa therapy. RESULTS: Compared to baseline, the EASI scores of the total group and the severe group decreased at 2, 3 and 4 weeks. Furthermore, the VAS for pruritus of the total group and the severe group was also decreased. Among the factors of the skin barrier function, the skin pH decreased in the mild group and it increased in the severe group during the spa therapy. Of the 15 patients, one patient experienced exacerbation of symptoms and two patients reported a transient pickling sensation during the spa therapy. CONCLUSION: Our study suggests that Hae-Un-Dae spa therapy could be an effective and safe modality for the management of adult AD, yet more studies should be performed to determine the therapeutic mechanism.
Adult ; Baths ; Dermatitis, Atopic ; Eczema ; Humans ; Hydrogen-Ion Concentration ; Pruritus ; Sensation ; Skin

No abstract available.
Humans ; Telangiectasis

No abstract available.
Hand* ; Hyperpigmentation* ; Vitamin B 12 Deficiency* ; Vitamin B 12* ; Vitamins*

Mycobacterium chelonae is a rapidly growing atypical mycobacterium found in soil and water. In a healthy person, it causes cutaneous infection after an invasive procedure or surgery. Herein, we present a case of a 52-year-old man with multiple erythematous plaques and nodules on the back and left arm, and these occurred at the site of bee sting therapy by a herbal medical doctor. The histologic findings showed a granulomatous infiltration composed of numerous neutrophils, lymphocytes, eosinophils, histiocytes and multinucleated giant cells. Acid fast bacilli were detected by Ziehl-Neelsen stain and Mycobacterium chelonae infection was confirmed by an INNO-LiPA mycobacteria kit. The patient was treated with 1 g of clarithromycin and 200 mg of doxycycline for 6 months and his condition improved considerably.
Arm ; Bees ; Bites and Stings ; Clarithromycin ; Doxycycline ; Eosinophils ; Giant Cells ; Histiocytes ; Humans ; Lymphocytes ; Middle Aged ; Mycobacterium chelonae ; Neutrophils ; Nontuberculous Mycobacteria ; Soil

No abstract available.
Child* ; Humans ; Mucinoses* ; Nevus, Pigmented*

No abstract available.
Asian Continental Ancestry Group ; Humans ; Keratosis ; Male

BACKGROUND: Topical corticosteroids are not uncommonly abused in patients with facial dermatoses. Although it is well known that uncontrolled use of topical corticosteroids cause steroid-induced rosacea, its clinical manifestation is not studied yet in Korean patients. OBJECTIVE: The purpose of this epidemiological study was to investigate a usage history of topical corticosteroid and clinical manifestation of steroid-induced rosacea. METHODS: Among the 424 rosacea patients who visited the dermatologic clinics of Pusan National University Hospital between January 2006 and May 2011, a face-to-face structured questionnaire was given to 66 rosacea patients with a history of topical corticosteroid use on the face for more than 1 month before onset of rosacea symptoms. Investigated factors include sex, age, history about use of topical corticosteroids and clinical manifestations. RESULTS: Of the 66 patients, 41 were female and 25 were male with the mean age of 52.1+/-14.6 (range 16~76) year. Celestone-G(R) (n=14) was the most commonly used product in the 34 patients who remembered the brand name of topical corticosteroids, which they had used. Forty-three patients used topical corticosteroids for treatment of facial skin lesions without diagnosis. Eighteen patients purchased topical corticosteroids without doctor's prescription. The mean duration and frequency of topical corticosteroid use was 3.8 years and 1.3 times per day, respectively. Constant erythema (n=31) was the most common symptom and it started to occur 2 months after use of topical corticosteroid. CONCLUSION: High-potency topical corticosteroids are frequently used for patients with facial dermatoses without correct diagnosis and without doctor's prescription. Besides, abuse of topical corticosteroids cause rosacea symptoms, such as constant erythema. To prevent the occurrence of steroid-induced rosacea, there should be a great social concern for abuse and misuse of topical corticosteroid in patients with facial dermatosis.
Adrenal Cortex Hormones ; Androsterone ; Epidemiologic Studies ; Erythema ; Facial Dermatoses ; Female ; Humans ; Male ; Prescriptions ; Rosacea ; Skin ; Surveys and Questionnaires

Isolated collagenoma usually occurs on the plantar area and is frequently associated with Proteus syndrome. A few reports have described isolated collagenoma on extra-plantar areas such as palm, scalp, face, thigh and finger. Herein, we report a case of isolated collagenoma on the periungual area, which was confused with digital mucous cyst. A 26-year-old man visited our clinic with an asymptomatic, 0.8x0.7 cm-sized, firm, skin-colored nodule on the periungual area of the left fourth finger. The distal nail of the nodule showed a longitudinal groove. Histopathologic findings from periungual nodule showed thickened collagen bundles packing reticular dermis.
Adult ; Collagen ; Dermis ; Fingers ; Humans ; Nails ; Proteus Syndrome ; Scalp ; Thigh