PURPOSE: CD5+ B (B1) cell is a subpopulation of B cells and CD5+ B cells constitute a large fraction of B cells in neonates. CD5 B cells are closely related with autoimmune diseases but the roles and functions in neonates are still unknown. The quantitative changes of CD5+ B cells in neonatal infections were examined to investigate the involvement of CDS+ B cells in neonatal immune reaction to general immunologic stimuli such as infections. Methods: Ten normal neonates and eight neonates with acute febrile diseases were studied. Venous blood was drawn and mononuclear cells were separated by Ficoll-Hypaque. Half was double-stained with FITC-conjugated anti-CD5 and PE-conjugated anti-CD19, and another half with FITC-conjugated anti-CD4 and PE-conjugated anti-CD8. Stained samples were analyzed using fluorescent-activated cell sortor. ...continue...
Autoimmune Diseases ; B-Lymphocytes* ; Humans ; Infant, Newborn

No abstract available.
Child* ; Humans ; Kidney Transplantation*

No abstract available.
Cerebrospinal Fluid* ; Child* ; Humans ; Lymphocytosis* ; Meningitis, Bacterial*

No abstract available.
Korea* ; Tuberculosis*

No abstract available.
Paraquat* ; Poisoning*

No abstract available.
Achondroplasia*

No abstract available.
Brain Neoplasms* ; Brain* ; Child* ; Humans

No abstract available.
Hydronephrosis*

No abstract available.
Humans ; Oxidoreductases* ; Urinary Tract Infections* ; Urinary Tract*

No abstract available.
Adrenal Hyperplasia, Congenital* ; Adrenogenital Syndrome*