1.Development of limbs in staged humn embryos.
Hyoung Woo PARK ; Yang Ki MIN ; Yong Woon SHIM
Korean Journal of Anatomy 1992;25(1):1-11
No abstract available.
Embryonic Structures*
;
Extremities*
2.Sleep and Suicidal Risk Factors in Korean High School Students.
Ja Hyun JEONG ; Yong E JANG ; Hae Woo LEE ; Hyun Bo SHIM ; Jin Sook CHOI
Sleep Medicine and Psychophysiology 2013;20(1):22-30
OBJECTIVES: Sleep problems has been consistently reported as a suicidal risk factor in adults and, recently, also in adolescents. In this study, dividing study subjects by the previous suicidal behaviors (suicidal vs non-suicidal), we compared the group differences of suicidal risk factors, and examined the possibility of sleep as a suicidal risk factor. METHODS: Study subjects were 561 (271 boys and 290 girls) from a community sample of high school students. Suicidal Risk Behavior Checklist, Center for Epidemiological Study-Depression (CES-D), Symptom Checklist-90-Revision (SCL-90-R) Anxiety and Aggression subscale, Pittsburg Sleep Quality Index (PSQI) were done. RESULTS: Forty six students (8.1%) reported previous actual self-harm behavior as a suicidal attempt, 181 students (32.4%) reported having suicidal thought only. Three hundred thirty four students (59.5%) reported no previous suicidal behavior (thought and attempt, both). Suicidal behavior group showed higher score on risk behaviors such as school violence, substance use and internet addiction. CES-D, SCL-90-R, PSQI showed significant group difference. Logistic regression analysis showed suicidal risk were significantly associated with depression, stress in suicidal risk factors and sleep latency, daytime dysfunction in PSQI. Analysis of variance (ANOVA) shows the most prolonged sleep latency and increased index of all PSQI components except sleep efficiency in suicidal attempt group. CONCLUSIONS: Sleep Problems had a strong association with the suicidal risk behavior in adolescents. Sleep problems, especially, prolonged sleep latency, daytime dysfunction might be important markers for suicidal behavior. Screening for sleep problems in adolescents are encouraged for the parents, school teachers, and related medical physicians.
Adolescent
;
Adult
;
Aggression
;
Anxiety
;
Checklist
;
Depression
;
Humans
;
Internet
;
Logistic Models
;
Mass Screening
;
Parents
;
Risk Factors
;
Risk-Taking
;
Suicide
;
Violence
3.Selective Microscopic Decompression for Lumbar Spinal Stenosis with Osteoporosis: More than 3 Years Follow Up.
Dae Moo SHIM ; Tae Gyun KIM ; Ha Heon SONG ; Yong Woo CHO
Journal of Korean Society of Spine Surgery 1998;5(2):278-283
OBJECTS: There was a trend to perform fusion and instrumentation in spinal stenosis surgery, because of extensive decompression and instability. However, the introduction of microscope in spine operation can minimize the range of excision of anatomical structure and reduced the decompressin level in the multiple lesions and the incidence of spinal fusion. The purpose of this study were to assess the outcome of this procedure in 3 years follow up and to identify the clinical features of the patients and technical aspects of the operation that were associated with a poor outcome. MATERIALS AND METHODS: Twenty-one patients were identified as having had a microscopic decompression without arthrodesis, for degenerative lumbar spinal stenosis over 60 years or their who had osteoporosis with Saville's index 2 or higher. The follow up period was more than 3 years. The clinical results was evaluated by Kim's criteria. RESULTS: Eleven cases were above good results in two levels involved 14 cases, 2 cases above good results in three levels involved 5 cases and 1 case above good results in four levels involved 2 cases. In the cases of affected duration, 7 cases are less than 1 year or more than 5 years each 6 cases and 2 cases were above good results by the criteria. We concluded that the long-term outcome of decompressive surgery in the elderly is good; it does not differ from that reported for younger patients . CONCLUSIONS: Selective microscopic decompression is one of the effective method for the elderly patients or patients with osteoporosis in addition to multiple stenotic lesions.
Aged
;
Arthrodesis
;
Decompression*
;
Follow-Up Studies*
;
Humans
;
Incidence
;
Osteoporosis*
;
Spinal Fusion
;
Spinal Stenosis*
;
Spine
4.Brachial Plexus Palsy after Thoracoscopic Sympathectomy: A case report.
Dong Eon MOON ; Jae Yong SHIM ; Jong Ho CHO ; Yoon Ki LEE ; Sung Woo PARK ; Cheol Joo PARK
Korean Journal of Anesthesiology 1997;33(4):753-756
We experienced a complication of brachial plexus palsy secondary to operative position during thoracoscopic thoracic sympathectomies. His general health was excellent and no previous histories vulnerable to peripheral nerve systems were observed. The thoracic sympathectomies were done under general anesthesia. The patient was placed left lateral position with his right arm abduced 150o on padded arm board. An operation was lasted 2 hours and 30 minutes at this position because of severe right apical lung adhesion. The controlateral side was performed same procedure and lasted 20 minutes. After the patient recovered from the anesthesia, the patient had a complete paralysis of right arm. There was also slightly diminished sensation to pinprick on the arm and hand. Neurologic examination and EMG study revealed brachial plexus palsy. Nerve blocks and physiotherapy were performed to treat brachial plexus injuries. His motor functions were improved day by day and he was discharged with a complete range of motion against gravity on 14th. postoperation day. However, there were loss of muscle powers against some resistances and tingling sensations of fingertips. Two months later, he was recovered completely and there was no residual disabilities.
Anesthesia
;
Anesthesia, General
;
Arm
;
Brachial Plexus*
;
Gravitation
;
Hand
;
Humans
;
Lung
;
Nerve Block
;
Neurologic Examination
;
Paralysis*
;
Peripheral Nerves
;
Range of Motion, Articular
;
Sensation
;
Sympathectomy*
5.A Case of Asymmetric Septal Hypertrophy Combined with Conn's Syndrome.
Mi Ok KIM ; Jang Keun IM ; Yong Woo JANG ; Chun Soo KANG ; Nam Wook KANG ; Won Bo SHIM
Korean Circulation Journal 1995;25(4):868-874
We report a case of a 44 year old femele with unilateral aldosterone-proudcing adrenal adenoma characterized by hypertension, plasma aldosterone excess, and low plasma renin, commonly but not invariably with hypokalemia. She also had asymmetric septal hypertrophy of left ventricle established with two-dimensional echocardiography. The electrocardiogram showed inverted T wave and prominent U wave with high QRS voltage on precordial leads. In the case of this patient, we are not sure whether asymmetric septal hypertrophy was caused by secondary hypertension and chronic aldosterone excess of primary aldosteronism, or hypertrophic cardiomyopathy per se, so further long=term follow-up is required to determine it. Following the successful unilateral adrenalectomy, however, the systemic pressure fell down to the normal level and electrolyte abnormalities were corrected immediaterly within a few days and the modest regression in septal hypertrophy was noted in one year, suggesting that the promary aldosteronism contributes to the development or porgression of asymmetric septal hepertrophy.
Adenoma
;
Adrenalectomy
;
Adult
;
Aldosterone
;
Cardiomyopathy, Hypertrophic*
;
Echocardiography
;
Electrocardiography
;
Follow-Up Studies
;
Heart Ventricles
;
Humans
;
Hyperaldosteronism*
;
Hypertension
;
Hypertrophy
;
Hypokalemia
;
Plasma
;
Renin
6.The cephalometric study of korean mandibular angle.
Jung Ha PARK ; Kyung Gyun HWANG ; Yong Jae KIM ; Soon Seop WOO ; Eem Hak YOO ; Kwang Sup SHIM
Journal of the Korean Association of Oral and Maxillofacial Surgeons 2003;29(4):226-231
The contour of mandibular angle is important for facial esthetics in the oriental population, because the wide and square face is thought to have had an unhappy life. A prominent mandibular angle produces a characteristics quardrangle, coase, and muscular appearance. So, uni- or bi-lateral mandibular angle reduction is usually performed. However, there is little guideline for bi-lateral angle reduction. So, this study was to investigate the pattern of Korean mandibular angle for bi-lateral mandibular angle reduction as guideline. This study was included 66 adult men and women over 19 years old who are having the normal mandibular angle. We measured the posterior border, angle, and inferior border of mandible using cephalometric view. The results of study was as followed : 1. The ratio of posterior mandible was 96.6, 97.3% in male, and 103.0, 106.0% in female. 2. The ratio of mandibular angle(R1-Go/R1-R2) was 120.2% in male, and 117.3% in female. 3. The ratio of inferior mandible(D5, 6, 7, E, F, G/D4) was 97. 3, 90.9, 79.5, 65.2, 57.8, 46.9% in male, and 98.5, 91.2, 80.5, 67.6, 59.1, 50.2 % in female. The results of this study should be useful to decide accurate amount of reduction.
Adult
;
Esthetics
;
Female
;
Humans
;
Male
;
Mandible
;
Young Adult
7.Mesenchymal stem cell therapy for liver fibrosis.
Young Woo EOM ; Kwang Yong SHIM ; Soon Koo BAIK
The Korean Journal of Internal Medicine 2015;30(5):580-589
Currently, the most effective treatment for end-stage liver fibrosis is liver transplantation; however, transplantation is limited by a shortage of donor organs, surgical complications, immunological rejection, and high medical costs. Recently, mesenchymal stem cell (MSC) therapy has been suggested as an effective alternate approach for the treatment of hepatic diseases. MSCs have the potential to differentiate into hepatocytes, and therapeutic value exists in their immune-modulatory properties and secretion of trophic factors, such as growth factors and cytokines. In addition, MSCs can suppress inflammatory responses, reduce hepatocyte apoptosis, increase hepatocyte regeneration, regress liver fibrosis and enhance liver functionality. Despite these advantages, issues remain; MSCs also have fibrogenic potential and the capacity to promote tumor cell growth and oncogenicity. This paper summarizes the properties of MSCs for regenerative medicine and their therapeutic mechanisms and clinical application in the treatment of liver fibrosis. We also present several outstanding risks, including their fibrogenic potential and their capacity to promote pre-existing tumor cell growth and oncogenicity.
Animals
;
Cell Differentiation
;
Cell Proliferation
;
Hepatocytes/immunology/metabolism/pathology/*transplantation
;
Humans
;
Liver/immunology/metabolism/pathology/physiopathology/*surgery
;
Liver Cirrhosis/diagnosis/immunology/metabolism/physiopathology/*surgery
;
Liver Regeneration
;
*Mesenchymal Stem Cell Transplantation/adverse effects
;
*Mesenchymal Stromal Cells/immunology/metabolism/pathology
;
Phenotype
;
Regenerative Medicine/*methods
;
Risk Factors
;
Signal Transduction
;
Treatment Outcome
8.Dual Plate Fixation for Displaced Transverse Fracture of the Lower Sacrum
Dong-Hyuk CHOI ; Ji-Hun PARK ; Seong-Woo SHIM ; Yong-Soo CHOI
The Journal of the Korean Orthopaedic Association 2020;55(2):178-182
Isolated fractures of lower sacrum are commonly treated conservatively in most cases because of low energy damage and stable fracture. However, surgical treatment is required in displaced unstable fracture. But the surgical technique is not established and even case reports are not common. We reported a case of displaced transverse fracture of the lower sacrum that was treated with an open reduction and dual plate fixation.
9.Delayed Pneumothorax after Thoracic Paravertebral Block
Dae Moo SHIM ; Ki Yong AN ; Ki Hyun KWON ; Young Woo CHUNG
The Journal of the Korean Orthopaedic Association 2023;58(1):62-66
This paper reports a case of a patient aged 63 years who developed a delayed pneumothorax after thoracic paravertebral block (TPVB). TPVB is a non-invasive procedure that is known to be relatively safe. A 63-year-old female was admitted with back pain. TPVB T9–10 left was then performed. Two days after the procedure, she complained of dyspnea in the emergency room. X-ray showed a pneumothorax in her left side with partial left lung collapse. The pneumothorax was managed by surgical intervention, and an intercostal tube was inserted. The post-procedural X-ray showed a fully expanded lung. A chest tube was taken out after 72 hours. A delayed pneumothorax can occur after TPVB. Therefore, careful observation is required after this procedure.
10.Clinical Significance of Serum Procalcitonin in Patients with Community-acquired Lobar Pneumonia.
Jin Yong LEE ; Su Jin HWANG ; Jae Won SHIM ; Hye Lim JUNG ; Moon Soo PARK ; Hee Yeon WOO ; Jung Yeon SHIM
The Korean Journal of Laboratory Medicine 2010;30(4):406-413
BACKGROUND: Community-acquired pneumonia (CAP) is a common respiratory disorder in children, which necessitates hospitalization. Bacterial pneumonia, especially lobar pneumonia and parapneumonic effusions, is associated with considerably severe clinical course and extensive alveolar infiltrates. Serum procalcitonin (PCT) level has been used to distinguish bacterial from viral infections, but its usefulness is disputed. The diagnostic accuracy and usefulness of PCT, C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), and white blood cell (WBC) count were determined by comparing their values in the patients with CAP with those in healthy controls. METHODS: The serum PCT levels, as well as CRP level, ESR, and WBC counts, were measured in 76 hospitalized patients with CAP (lobar pneumonia, 16; bronchopneumonia, 60) and 18 healthy controls. Serum PCT level was measured using VIDAS(R) BRAHMS PCT (Biomerieux, France), and ROC curve analysis was performed to evaluate its diagnostic accuracy. RESULTS: Serum PCT levels were higher in the patients with CAP than in healthy controls, especially in the patients with lobar pneumonia than in those with bronchopneumonia. Serum CRP level was also significantly elevated in the patients with CAP, especially in those with lobar pneumonia. The diagnostic accuracy of serum PCT level for the diagnosis of lobar pneumonia was better than those of serum CRP level and ESR. The serum PCT level was significantly correlated with the CRP level, ESR, and WBC count. CONCLUSIONS: Serum PCT level was a better marker than CRP level or ESR for the diagnosis of lobar pneumonia in children with CAP.
Adolescent
;
Biological Markers/blood
;
Blood Sedimentation
;
Bronchopneumonia/complications
;
C-Reactive Protein/analysis
;
Calcitonin/*blood
;
Child
;
Child, Preschool
;
Community-Acquired Infections/complications/*diagnosis
;
Female
;
Humans
;
Infant
;
Infant, Newborn
;
Leukocyte Count
;
Male
;
Pneumonia/complications/*diagnosis
;
Protein Precursors/*blood
;
ROC Curve