1.A Clinical Study on the Liver Cirrhosis in Children: Review of 40 Cases.
Je Woo KIM ; Ki Sup CHUNG ; Chan Il PARK
Journal of the Korean Pediatric Society 1995;38(11):1506-1514
No abstract available.
Child*
;
Humans
;
Liver Cirrhosis*
;
Liver*
2.A Case of Hernolytio Disease of the Newborn due to Anti-Dib Antibody.
Hee Chung KIM ; Mi Jung KANG ; Jong Hee CHAE ; Woo Sup SHIM ; Chung Hyun NAHM ; Kyou Sup HAH
Korean Journal of Blood Transfusion 1994;5(2):151-158
The Di(a+b-) phenotype is extremely rare among Caucaclans and mostly confined to mongoloids. The incidences of Di antigen among Koreans were reported to be 6.1 to 14.5%, with an average of 9.6%; it can be calculated that the frequency of Di(a+b-) is 0.25% on the average. Authors report the first case of hemolytic disease of the newborn due to anti-Dib in Korea. The Diego phenotypes of the mother, baby and father were Di(a+b-), Di(a+b+) and Di (a-b+), respectively. The mother's serum and eluate from infant's erythrocytes contained anti-DP antibody active in the antiglobulin phase. After transfusions of Di-negative red cells from the mother and mother's relative, the patient was recovered from anemia and jaundice.
Anemia
;
Erythrocytes
;
Fathers
;
Humans
;
Incidence
;
Infant, Newborn*
;
Jaundice
;
Korea
;
Mothers
;
Phenotype
3.Polyorchidism; a case report.
Korean Journal of Urology 1992;33(5):929-931
We describe an 22-yeer-old man with polyorchidism whose both ipsilateral testes were located in the inguinal area and scrotum. Polyorchidism is a rare anomaly with approximately 70 cases reported in the literature. In this report the literature is reviewed and the etiology of this anomaly is discussed briefly.
Scrotum
;
Testis
4.Distribution of 123I, 99mTc-human polyclonal nonspecific IgG and 67Ga-citrate in abscess bearing mice.
Sang Moo LIM ; Kwang Sun WOO ; Wee Sup CHUNG ; Ok Doo AWH ; Yong Sup SEO ; Jong Doo LEE
Korean Journal of Nuclear Medicine 1992;26(1):116-123
No abstract available.
Abscess*
;
Animals
;
Immunoglobulin G*
;
Mice*
5.In Vivo Image and Biodistribution of 123I-15-(p-iodophenyl)-3-R , S - methylpentadecanoic acid ( BMIPP ) in Liposarcoma Bearing Nude Mice.
Chang Woon CHOI ; Sang Moo LIM ; Tae Sup LEE ; Yong Sup SUH ; Kwang Sun WOO ; Wee Sup CHUNG ; Soo Jung LIM ; Ok Doo AWH
Korean Journal of Nuclear Medicine 2001;35(5):324-333
No abstract available.
Animals
;
Liposarcoma*
;
Mice
;
Mice, Nude*
6.Gamma Knife Radiosurgery for Juxtasellar Tumors.
Jong Hee CHANG ; Jin Woo CHANG ; Yong Gou PARK ; Sang Sup CHUNG
Journal of Korean Neurosurgical Society 2000;29(10):1345-1351
No abstract available.
Radiosurgery*
7.Serum gastrin and pepsinogen I, II concentrations in children with Helicobacter pylori infection: the role of CagA and VacA.
Yonsei Medical Journal 1998;39(2):159-165
Serum gastrin and pepsinogen concentrations were measured in 51 children infected with Helicobacter pylori, to investigate the clinical significance and influence of CagA and VacA on serum concentrations of these peptides. CagA+ was 44/51 (86%) and VacA+ was 42/51 (82%). Type I (CagA+/VacA+) included 39/51 (76%), type II (CagA-/VacA-) was 4/51 (8%), and intermediate (CagA-/VacA+, CagA+/VacA-) was 8/51 (16%). There was no significant correlation between endoscopic diagnosis and the state of CagA/VacA. Serum gastrin concentrations were not significantly correlated with the state of CagA/VacA. Serum pepsinogen I and II concentrations were significantly higher in CagA+ than in CagA-, but there was no significant difference between VacA+ and VacA-, Serum pepsinogen I/II ratio was not significantly correlated with the state of CagA/VacA. There was no significant difference between serum concentrations of gastrin, pepsinogen I and H. pylori phenotypes. However, pepsinogen II concentration was significantly higher in type I than type II. Pepsinogen I/II ratio was significantly lower in type I and intermediate than in type II. These findings suggest that CagA positively and phenotype of H. pylori could play a role in the development of upper gastrointestinal diseases in children.
Adolescence
;
Bacterial Proteins/physiology*
;
Bacterial Proteins/blood
;
Child
;
Child, Preschool
;
Female
;
Gastrins/blood*
;
Gastrointestinal Diseases/blood
;
Helicobacter Infections/physiopathology
;
Helicobacter Infections/blood*
;
Helicobacter pylori*/genetics
;
Human
;
Male
;
Osmolar Concentration
;
Pepsinogens/blood*
;
Phenotype
8.Serum Pepsinogen l, ll Levels and Upper Gastrointestinal Diseases in Children with H. pylori Infection.
Journal of the Korean Pediatric Society 1998;41(2):200-208
PURPOSE: In H. pylori infection serum pepsinogen l/ll ratio decreases and pepsinogen ll level is increased. Increased serum pepsinogen ll level correlates with pathologic severity of gastritis. We assayed serum pepsinogen l, ll levels and pepsinogen l/ll ratio to evaluate the relationship between the serum pepsinogen level and upper gastrointestinal diseases. METHODS: One hundred and sixty-five children who had undergone upper gastrodudenal endoscopic examination with CLO test and silver stain were included. Pepsinogen l and ll levels were detected in serum by radioimmunoassay. RESULTS: Age distributions were: 3 patients below 5 years, 55 patients between 6 and 10 and 107 over 11. Thirty-two (19%) were H. pylori positive, and 133 (81%) were negative. Pepsinogen l increased in H. pylori positive children (P<0.01). Pepsinogen ll were higher in the H. pylori positive patients compared to Helicobactor negative group (P<0.001). Pepsinogen l and II were significantly higher (P<0.01 in pepsinogene l: P<0.01 in ll) in children with nodular gastritis with Helicobactor positive than any other disease including H. pylori negative without duodenal ulcer. Pepsinogen l/ll ratio was lower in children with nodular gastritis with H. pylori positive (P<0.001) than in children with any other disease including Helicobacter negative. CONCLUSION: These results suggest that serum pepsinogen levels are inportnat in pathogenesis of upper gastrointestinal disease in children with H. pylori infection.
Age Distribution
;
Child*
;
Duodenal Ulcer
;
Gastritis
;
Gastrointestinal Diseases*
;
Helicobacter
;
Humans
;
Pepsinogen A*
;
Radioimmunoassay
;
Silver
9.The Clinical Results of Conservative Treatment of Frozen Shoulder Using Continuous Passive Motion.
Hoe Jeong CHUNG ; Doo Sup KIM ; Yeo Seung YOON ; Dong Woo LEE ; Kyung Jin HONG
Clinics in Shoulder and Elbow 2015;18(4):217-220
BACKGROUND: The purpose of this study is to administer conservative treatment in 30 patients diagnosed with idiopathic frozen shoulder, following the suggested frozen shoulder rehabilitation program and to assess the clinical outcome using a prospective study. METHODS: Thirty patients diagnosed with idiopathic frozen shoulder, treated with steroid hormone injection on the articular joint with an intra-articular steroid (triamcinolone 40 mg + lidocaine 4 ml) injection and started on stepwise shoulder extension exercise were chosen. The subjects were divided into two groups of 15 people each with one group undergoing rehabilitation with continuous passive motion (CPM) and the other group without it. Follow-ups were done before rehabilitation and at 4-week intervals with the 24th being the final week. At every follow-up, passive range of motion (ROM) was measured and surveys on pain and clinical score were administered. RESULTS: In the last follow-up, both groups showed statistically significant improvements in all evaluation criteria. However, no statistical difference in all values of the ROM and Constant score evaluation criteria was observed between the groups. Only in the last follow-up, group 1 had a visual analog scale (VAS) score of 2.4 +/- 2.1 points, which was lower, with statistical significance, than the VAS score of group 2, which was 4.4 +/- 3.1 points (p<0.001). CONCLUSIONS: Study using CPM in treatment of frozen shoulder has been inadequate, meaning that there is still room for improvement and need for more study on setting a more specific protocol and guidelines for this procedure.
Bursitis*
;
Follow-Up Studies
;
Humans
;
Joints
;
Lidocaine
;
Motion Therapy, Continuous Passive
;
Prospective Studies
;
Range of Motion, Articular
;
Rehabilitation
;
Shoulder
;
Visual Analog Scale
10.Effects of Fetal Nondopaminergic Cortical Tissue Transplantation in the Rat Parkinsonian Model.
Jin Woo CHANG ; Sang Sup CHUNG
Journal of Korean Neurosurgical Society 1994;23(5):487-498
Fetal dopaminergic or nondopaminergic cortical tissues were implanted directly into the denervated striatum of partial lesioned rat parkinsonian models. After transplantation, at rats were behaviourally tested with apomorphine and sacrificed for tyrosine hydroxylase immunohistochemical stain. The results of this study are summarized as follows : 1) Of 45 rats partially lesioned with 6-hydroxydopamine, 17 rats(37.8%) met a criteria(a minimum of 4 times/min to apomorphine-induced rotation test) of the rat parkinsonian model. 2) Eight weeks after transplantation of the fetal dopaminergic tissues into the striatum of the rat parkinsonian model, transplanted dopaminergic cells were found to be alive. Also reinnervated dopaminergic fibers were found in the previously denervated striatum. And the behavioural study suggested that the transplantation of the fetal dopaminergic neurons had influenced on the apomorphine-induced rotation. 3) Eight weeks after transplantation of the fetal nondopaminergic tissues into the striatum of the rat parkinsonian model, dopaminergic cells were not found in the previously denervated striatum. However, reinnervation of the dopaminergic fibers were found in the preciously denervated striatum. However, reinnervation of the dopaminergic fibers were found in the previously denervated striatum as well as the reduction of the apomorphine-induced rotation compared to the pregraft state. The major finding of this study support a trophic hypothesis for the mechanism of recovery in response to fetal dopaminergic or nondopaminergic tissue. The author conclude that fetal nondopaminergic tissue also had some beneficial effect in reducing apomorphine-induced rotational asymmetry probably by promoting recovery or sprouting of remaining dopaminergic fibers at the previously denervated striatum of the rat parkinsonian model.
Animals
;
Apomorphine
;
Dopaminergic Neurons
;
Oxidopamine
;
Rats*
;
Tissue Transplantation*
;
Transplantation
;
Transplants*
;
Tyrosine 3-Monooxygenase