Weber-Christian disease is a relapsing, febrile, nodular, nonsuppurative inflammation of the subcutaneous fat tissue. Many authors reported these cases which illustrate the great variability of the clinical manifestation, such as acute or chronic, fulminating or transient, febrile or non febrile, systemic or cutaneous. Two of our cases have had recurrent painful subeutaneous nodules without fever for several years. Biopsy showed a nonspecific inflammatory panniculitis with lymphocytes chiefly, and small amount of histiocytes and foamy cells. It should be suggested Weber-Christian disease when subcutaneous nodules appear recurrently same areas of the whole body surface except anterior aspects of tibia even if no fever as systemic manifestation. Treatment with steroid and chloroquine diphosphete produced good improvement.
Biopsy ; Chloroquine ; Fever ; Histiocytes ; Inflammation ; Lymphocytes ; Panniculitis ; Panniculitis, Nodular Nonsuppurative* ; Subcutaneous Fat ; Tibia

Urticaria is a common disease and a well known reaction pattern of the skin eharacterized by erythema or wheals and edema, that is the results of a local leakage ef plasma, from minute vessels into the connective tissue of the dermis. Seven hundred and sixty cases of urticaria visited to this department from January 1973 to December 1974 were studied clinically in various ways. Patients were classified as acute and chronic urticaria-acute form when the hives have been present for less than 8 weeks and chronic form when the hives lasted longer. In all patients, a detailed history, a complete physical examination, a total and differential leukocyte count, erythrocyte sedimentation rate and routine stool examination were performed. Foods were incriminated as the exciting causes of urticaria by history, diet elimination test and ingestion test. An ice cube test was done for corroboration of cold allergy. Cholinergic urticaria, was diagnosed by the appearance of small wheals surrounded by erythema after exercise, emotional disturbances or hot drinks. The diagnosis of urticaria due to drug was based on the history of urticaria following the taking of a certain drug. Infection as the inciting cause was determined by history and physical examination. The results: 1. The incidence of urticaria is 4. 6% to total number of dermatologic patients. 2. Among the 760 urticaria patients, acute cases were 498 which were 2 times more than chronic cases, and female patients were 474 cases that revealed marked high incidences than male patients. 3. The age of the patients ranged from 2 months to 87 years, and the patients between 20 and 39 years occupied more than half of the all patients. 4. Abnormal hematologic findings were more marked in acute form; leukocytosis and neutrophilia were dominate in acute form, and lymphocytosis and eosinophilia were more marked in chronic form. 5. Among the etiologic factors, the bacterial infection was the most frequent which occupied 22. 4% of the all urticaria patients. 6. Seven cases of urticaria due to parasites were clonorchis sinensis, in which I had experienced the complete recovery with the treatment of subcutaneous injection of clonorchis sinensis antigen (1: 10,000) 0.01- 0.1ml at the interval of one week. 7. In this study, the inciting or perpetuating causes could not be found in 50.8% of patients-46.2% of acute form and 59.5% of chronic form.
Affective Symptoms ; Bacterial Infections ; Blood Sedimentation ; Clonorchis sinensis ; Connective Tissue ; Dermis ; Diagnosis ; Diet ; Eating ; Edema ; Eosinophilia ; Erythema ; Female ; Humans ; Hypersensitivity ; Ice ; Incidence ; Injections, Subcutaneous ; Leukocyte Count ; Leukocytosis ; Lymphocytosis ; Male ; Parasites ; Physical Examination ; Plasma ; Skin ; Urticaria*

No abstract available.
Humans ; Peptic Ulcer*

One case of cerebral embolism developed during cessation of supraventricular tachycardia in Wolff-Parkinson-White syndrome is reported with brief review. Twenty five years old, male was admitted to Seoul National University hospital with palpitation. He had numerous episodes of paroxysmal tachycardia for 3 years. He was diagnosed as Wolff-Parkinson-White syndrome at this hospital, ca 6 months prior to admission. Wolff-Parkinson-White syndrome was improved with atropine test at that time. The electrocardiogram on admission revealed Wolff-Parkinson-White synd rome associated with supraventricular tachycardia. He developed cerebral embolism after paroxysmal tachycardia of 22 days.
Atropine ; Electrocardiography ; Humans ; Intracranial Embolism* ; Male ; Seoul ; Tachycardia, Paroxysmal* ; Tachycardia, Supraventricular ; Wolff-Parkinson-White Syndrome*

No abstract available.
Adult ; Antigens, CD31/metabolism ; Antigens, CD34/metabolism ; Female ; Hemangioendothelioma, Epithelioid/metabolism/*pathology/radiography ; Humans ; Immunohistochemistry ; Liver Neoplasms/metabolism/*pathology/radiography ; Magnetic Resonance Imaging ; Positron-Emission Tomography ; Tomography, X-Ray Computed ; von Willebrand Factor/metabolism

We report a case of atrophoderma of Pasini and Pierini in which the characteristic soft atrophic patch with cliffdrop border developed on the neck and two well-demarcated indurated atrophic patches were on both shoulders. We took biopsies from centers and margins of each lesion. Histipathologic findings from atrophic center showed marked dermal atrophy comparing to that from margin of the lesion on the neck, but the atrophic center and margin of the lesion on the shoulder showed morphea-like features without, distinct differences between two.
Atrophy ; Biopsy ; Neck ; Shoulder

No abstract available.
Interleukin-6* ; Rabbits*

No abstract available.
Alcoholics* ; Humans

No abstract available.
Cyclophosphamide* ; Hypersensitivity*

Lichen amyloidosis is a chronic, benign and relatively rare disease, but not infrequent in Korea. The patients with lichen amyloidosis visited to Dermatologic Department of Severance Hospital in 1969. The results of clinico-pathological findings observed in above patients were presented. Case 1-A 56 year old farmer has been suffered from pruritic lichenoid papules which developed in the right pretibial area for 10 years. These papules were reddish-brown in color, 1 to 2mm in. diameter and closely aggregated. The whole gross lesion measured 10 by 25 cm. Cases 2-A 32 year old obese house-wife complained of pruritic eruptions in the right pretibial area for 3 years. Shiny firm papules, measuring approximately 2 mm in diameter, were red in color and gross entire lesion was estimated to 7 by 10 cm. Histological examination by employing the stain method of crystal violet and the Nomland test demonstrated the amyloid mass in the papillary portion of dermis. All laboratory studies including complete blood count (CBC), chest X-ray, sedimentation rate, urinalysis (including test for Bence Jones protein), blood glucose, blood urea nitrogen (BUN), serum cholesterol, venereal disease research laboratories test for syphilis (VDRL), stool for occult blood, serum protein electrophoresis, electrocardiogram (ECG) and intravenous congo red test, were within normal limit. The therapeutic results were not promissing, however itching and lichenoid papules were disappeared during the treatment with steroid cream for occlussive dressing therapy.
Adult ; Amyloid ; Amyloidosis* ; Bandages ; Blood Cell Count ; Blood Glucose ; Blood Urea Nitrogen ; Cholesterol ; Congo Red ; Dermis ; Electrocardiography ; Electrophoresis ; Gentian Violet ; Humans ; Korea ; Lichens* ; Middle Aged ; Occult Blood ; Pruritus ; Rare Diseases ; Sexually Transmitted Diseases ; Syphilis ; Thorax ; Urinalysis