1.A case report of cerebral sparganosis associated with seizure.
Kyung Sik KOH ; Tae Yul CHOI ; Ik YANG ; Woo Suk CHOI ; Sun Yung SHIN ; Hwan Jo SUH
Korean Journal of Infectious Diseases 1993;25(4):393-398
No abstract available.
Seizures*
;
Sparganosis*
2.Toxicological Profiles of Poisonous, Edible, and Medicinal Mushrooms.
Woo Sik JO ; Md Akil HOSSAIN ; Seung Chun PARK
Mycobiology 2014;42(3):215-220
Mushrooms are a recognized component of the human diet, with versatile medicinal properties. Some mushrooms are popular worldwide for their nutritional and therapeutic properties. However, some species are dangerous because they cause toxicity. There are many reports explaining the medicinal and/or toxic effects of these fungal species. Cases of serious human poisoning generally caused by the improper identification of toxic mushroom species are reported every year. Different substances responsible for the fatal signs and symptoms of mushroom toxicity have been identified from various poisonous mushrooms. Toxicity studies of mushroom species have demonstrated that mushroom poisoning can cause adverse effects such as liver failure, bradycardia, chest pain, seizures, gastroenteritis, intestinal fibrosis, renal failure, erythromelalgia, and rhabdomyolysis. Correct categorization and better understanding are essential for the safe and healthy consumption of mushrooms as functional foods as well as for their medicinal use.
Agaricales*
;
Bradycardia
;
Chest Pain
;
Diet
;
Erythromelalgia
;
Fibrosis
;
Functional Food
;
Gastroenteritis
;
Humans
;
Liver Failure
;
Mushroom Poisoning
;
Poisoning
;
Renal Insufficiency
;
Rhabdomyolysis
;
Seizures
3.A Clinical Study of TravogenR and TravocortR / TravogenR Therapy in Superficial Fungal Diseases: Multicenter Trials.
Do Sik SONG ; Byung In RO ; Chin Yo CHANG ; Kang Woo LEE ; Kyung Jin RHIM ; Yong Woo CINN ; Kyung Sool KWON ; chang Jo COH ; Jang Kyu PARK
Korean Journal of Dermatology 1984;22(3):255-262
Isoconazole nitrate is one of the broad-spectrum antimycotic agents recently developed from imidazole derivatives. Authors performed ulticenter trials to evaluate the therapeutic effect of Travogen and Travocort in superficial fungal diseases. In the usual superficial fungal diseases, Travogen was applied 4 weeks. In the inflammatory and eczematoid superficial fungal diseases, Travocort was applied 2 weeks initially and then followed by 2 weeks application of Travogen. One hundred and ninty one patients with superficial fungal diseases were included in this study during g months from December, 1982 to August, 19$3 The obtained results were as follows; The overall cure rate of Travogen and Travocort in each superficial fungal diseases were gl 7g (tinea pedis), 98. L% (tinea cruris), 1ppg, (tinea corporis), 9g. 100% (tinea manus), 1ppg (tinea capitis) and 1pgg (candidiasis) respectively. Trichophyton rubrum(51. 3%), Trichophyton mentagrophytes(29.3g), Tricho -countinue-
Humans
;
Trichophyton
4.In vitro activities of eight antibiotics against methicillin-resistant S. aureus and S. epidermidis strains isolated in Korea.
Woo Hyun CHANG ; Myung Sik CHOI ; Hee Young CHUNG ; Whan Jo SEO ; Tae Yeol CHOI ; Yun Sop CHONG ; Jae Sik KIM ; Sun Sik CHUNG ; Suk Hee HONG
Journal of Korean Medical Science 1988;3(2):45-50
Staphylococcus aureus and Staphylococcus epidermidis strains isolated at eight large medical centers in Korea were examined for methicillin resistance and resistance to eight other antibiotics; cefazolin, cefamandole, cefuroxime, cefoxitin, cefotaxime, moxalactam, penicillin G and vancomycin. Methicillin resistance was found in 296 of 1225 strains (24.2%) of S. aureus and 126 of 348 strains (36.2%) of S. epidermidis. Methicillinresistant strains were isolated from all sources with the frequency of isolation ranging from 11% to 60%. From pleural effusion, throat swab and blood, methicillin-resistant strains of S. aureus were more frequently isolated with statistical significance (Chi-squared test, 95% confidence). Almost all of Methicillin-resistant S. aureus (MRSA) and S. epidermidis (MRSE) strains were multiply resistant to one or more tested eight antibiotics. However only 7(2.4%) of 296 MRSA strains and 2(1.6%) of 126 MRSE strains were resistant to vancomycin. Vancomycin was the most effective antibiotic against staphylococcal isolates as well as MRSA and MRSE.
Anti-Bacterial Agents/*pharmacology
;
Cross Infection/microbiology
;
Drug Resistance, Microbial
;
Humans
;
Korea
;
Staphylococcal Infections/microbiology
;
Staphylococcus aureus/*drug effects/isolation & purification
;
Staphylococcus epidermidis/*drug effects/isolation & purification
5.Evaluation of Severity of Coronary Artery Disease by Exercise Electrocardiographic Test.
Jin Yong HWANG ; Sung Wan KWANG ; Eon Jo WOO ; Shung Chull CHAE ; Jae Eun JUN ; Wee Hyun PARK ; Kee Sik KIM ; Kwon Bae KIM
Korean Circulation Journal 1991;21(1):40-46
Exercise-induced ischemic ST responses were analyzed in 36 patients who presented with chest pain and had exercise test and the results were compared with their coronary angiographic findings. Among 36 exercise test positives, the incidences of one-, two- and three vessel disease, and left main disease were 25%(9 cases), 30%(11 cases), 25%(9 cases) and 9%(3 cases), respectively. The incidence of multivessel disease(i.e., two-to three vessel disease or left main disease) in patients with ST depression > or =2.0mm was 72% and that in those with ST depression of 1.0-1.9mm was 45%. In patients with downsloping ST depression, the incidence of multivessel disease was significantly higher than that of one vessel disease(86% vs 14%, p<0.001). But both incidences of one vessel disease and multivessel disease were similar in patients with flat and slowly upsloping ST depression. More than two thirds of patients with ischemic ST depression appearing in the first 6 minutes of exercise or those lasting past 7 minutes in recovery were associated with multivessel disease. It is concluded that attention to depth, type, appearance time and duration of ST depression during exercise test is particularly helpful in detecting patients with advanced coronary disease.
Chest Pain
;
Coronary Artery Disease*
;
Coronary Disease
;
Coronary Vessels*
;
Depression
;
Electrocardiography*
;
Exercise Test
;
Humans
;
Incidence
6.A Clinical Review of Geriatric Anesthesia - an Analysis of 601 Cases .
Kang Woo LEE ; Man Sik YANG ; Yoon Gie MIN ; Byung Jo CHOI
Korean Journal of Anesthesiology 1981;14(4):443-452
A total of 601 anesthesias given to the patients over age 60 who were admitted to Han Gang Sung Shim Hospital during the period from Jan. 1976 to Dec. 1980, were subjected to this clinical review. 1) Of the total 15,609 cases, 601 cases(3.8%) were over 60 years of age consisting of 315 male(52.4%) and 286 female(47.6%). 2) Among the 601 geriatric patients, 453 cases were 60~69 years of age(75.4%), 128 cases were 70~79 years of age(21.3%) and 20 cases were over 80 years of age(3.3%). 3) In the surgical group, 358 cases(59.7%) were general surgery, 120 cases(20.0%) were orthopedic surgery, 34 cases(5.6%) were urology, 20 cases(3.3%) were gynecology respectively. 4) The techniques of anesthesia were 545 cases(90.7%) of general anesthesia, 22 cases(3.7%) of spinal anesthesia and 17 cases(2.8%) of axillary block. 5) Anesthetics were diethly-ether 24 cases(36.3%) and halothane 22 cases(33.3%) in 1976. But there were 5 diethly-ether cases(0.3%) and 120 halothane cases(91.6%) in 1980. 6) For the duration of anesthesia, 81 cases(13%) were within 1 hour, 238 cases(39.6%) within 2 hours, 156 cases(26.0%) within 3 hours and 21 cases over 5 hours. 7) In the classification of physical status of the geriatric patients, 42 cases(7.0%) were class l, 201 cases(33.2%) were class ll, 109 cases (18.1%) were class lll and 8 cases(1.3%) were class lV. 8) Emergency cases were 223 cases(37.1%) and 378 cases(62.9%) were elective. 9) The findings of preoperative chest X-rays revealed that 227 cases(48.8%) were within normal limits, 56 cases(12.0%) had hypertensive heart disease, 24 cases(5.1%) had senile fibrosis, 22 cases(5.1%) had unstabilized tuberculosis and 14 cases(3%) had pneumonis. 10) In the preoperative R.K.G., which covered 50% of the patients, 115 cases(38.3%) were within normal limit, 41 cases(13.6%) showed L.V.H., 30 cases(10.0%) had sinus bradycardia, 13 cases (4.3%) had myocardial lschemia and 7 cases(2.3%) had R.B.B.B. 11) Post-operative mortality rate was 5.8% in 1976, 4.0% in 1977, 3.6% in 1978 and 2.1% in 1980, and over all mortality rate was 3.1%.
Anesthesia*
;
Anesthesia, General
;
Anesthesia, Spinal
;
Anesthetics
;
Bradycardia
;
Classification
;
Emergencies
;
Fibrosis
;
Gynecology
;
Halothane
;
Heart Diseases
;
Humans
;
Mortality
;
Orthopedics
;
Thorax
;
Tuberculosis
;
Urology
7.Double-blind, Placebo-controlled, Multi-center Study for Therapeutic Effects of Mountain Panax Ginseng C.A. Meyer Extract in Men with Erectile Dysfunction: a Preliminary Report.
Hong Sik KIM ; Seung Hyo WOO ; Shunghwan JO ; Eun Joo HAHN ; Nae Young YOUN ; Hyung Lae LEE
Korean Journal of Andrology 2006;24(2):84-88
PURPOSE: We investigated the effect of 100-year-old mountain ginseng(Panax ginseng C.A. Meyer, PG-CAM) extract on patients with erectile dysfunction(ED). MATERIALS AND METHODS: A total of 35 patients with ED(23 patients in PG-CAM administration group, 12 in placebo group) were enrolled in this double-blind study. The drug was administered for 12 weeks. Before and after administration, patients took the self-administered IIEF-5 questionnaire and were tested for serum hormone levels(testosterone, LH, FSH, estradiol), complete blood count, liver and renal function test, and urinalysis. RESULTS: The IIEF-5 scores for the placebo group were 19.7+/-2.3 and 19.9+/-3.6 before and after treatment, respectively. For all patients taking PG-CAM, IIEF-5 scores increased 18.1+/-5.6 to 20.2+/-4.5. For those patients with initial scores below 17, IIEF-5 scores increased from 12.4+/-6.2 to 19.7+/-6.7. These results indicate that PG-CAM may increase erectile function in ED patients, particularly those with poor erection. No changes were detected in hormonal levels or blood tests. No toxic side effect were reported. CONCLUSIONS: IIEF-5 score improved significantly in ED patients treated with PG-CAM, suggesting that PG-CAM extract could be a treatment candidates for ED.
Blood Cell Count
;
Double-Blind Method
;
Erectile Dysfunction*
;
Hematologic Tests
;
Humans
;
Liver
;
Male
;
Panax*
;
Penis
;
Surveys and Questionnaires
;
Urinalysis
8.Double-blind, Placebo-controlled, Multi-center Study for Therapeutic Effects of Mountain Panax Ginseng C.A. Meyer Extract in Men with Erectile Dysfunction: a Preliminary Report.
Hong Sik KIM ; Seung Hyo WOO ; Shunghwan JO ; Eun Joo HAHN ; Nae Young YOUN ; Hyung Lae LEE
Korean Journal of Andrology 2006;24(2):84-88
PURPOSE: We investigated the effect of 100-year-old mountain ginseng(Panax ginseng C.A. Meyer, PG-CAM) extract on patients with erectile dysfunction(ED). MATERIALS AND METHODS: A total of 35 patients with ED(23 patients in PG-CAM administration group, 12 in placebo group) were enrolled in this double-blind study. The drug was administered for 12 weeks. Before and after administration, patients took the self-administered IIEF-5 questionnaire and were tested for serum hormone levels(testosterone, LH, FSH, estradiol), complete blood count, liver and renal function test, and urinalysis. RESULTS: The IIEF-5 scores for the placebo group were 19.7+/-2.3 and 19.9+/-3.6 before and after treatment, respectively. For all patients taking PG-CAM, IIEF-5 scores increased 18.1+/-5.6 to 20.2+/-4.5. For those patients with initial scores below 17, IIEF-5 scores increased from 12.4+/-6.2 to 19.7+/-6.7. These results indicate that PG-CAM may increase erectile function in ED patients, particularly those with poor erection. No changes were detected in hormonal levels or blood tests. No toxic side effect were reported. CONCLUSIONS: IIEF-5 score improved significantly in ED patients treated with PG-CAM, suggesting that PG-CAM extract could be a treatment candidates for ED.
Blood Cell Count
;
Double-Blind Method
;
Erectile Dysfunction*
;
Hematologic Tests
;
Humans
;
Liver
;
Male
;
Panax*
;
Penis
;
Surveys and Questionnaires
;
Urinalysis
9.A Case of Thoracic Disc Herniation Treated by Transthoracic Transpleural Approach.
Myung Sik KIM ; Il Woo LEE ; Tae Hoon JO ; Jin Un SONG ; Chi Kyung KIM
Journal of Korean Neurosurgical Society 1987;16(1):297-303
Thoracic disc herniation is uncommon and only represents 0.25% to 0.75% of all symptomatic disc lesions. The difficulty in diagnosis has been the one of the major problems in the treatment of thoracic disc herniation. But at now, the use of computed tomography with or without water soluble contrast media makes the diagnosis more acurate. Recently, we diagnosed a case of T4, T5 disc herniation by computed tomography with iopamidol. Operation by transthoracic, transpleural approach was done with microsurgical technique, and the result was good. The case is reviewed and other surgical techniques on the literature is discussed.
Contrast Media
;
Diagnosis
;
Iopamidol
10.Experimental study on the prefabricated tram flap of rabbits with enhanced neovascularization.
Yeong Jo KIM ; Seung Kyu HAN ; Byung IL LEE ; Woo Kyung KIM ; Jae Sik HAN
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1998;25(2):220-230
There are occasions when standard techniques of reconstructive surgery for traumatic injury, tumor resection, and correction of congenital anomalies cannot be used as a result of the unavailability of tissues, absence of healthy vascular pedicle or excessive morbidity in donor area. It is established that autogenous skin, muscle, bone, and other composite tissue can retain their viability in varying degree as a prefabricated `flap with vascular pedicle implantation and the survival rate of these flaps has increased with tissue expansion or PGE1 infusion. The purpose of this study was to demonstrate the reliability of the secondary or prefabricated rectus abdominis musculocutaneous flap, and to evaluate the effect of the several factors on the survival routes of these flaps. Fifty New Zealand white rabbits weighing from 250 to 350 gm were used for the study. On the abdominal area bipedicled skin flaps are elevated as a random pattern flaps and were prefabricated using with rectus muscle. The fifty flaps were studied. They were divided into the five groups as follows; group I, 10 x4 cm classic axial pattern transverse rectus abdominis muscle (TRAM ) flaps were made as a control group (n = 10); groupII, 10 x4 cm random pattern bipedicled skin flaps were prefabricated using right rectus muscle with the delay procedure(n = 10); group III, 5 x4 cm prefabricated musculocutaneous flap were made same as group II on the right, side, tissue expansion was performed on the left side (n = 10); group IV, same procedure was performed as group II, and in addition postoperative intravenous infusion of PGE1 was given(n = 10); group V, same procedure was performed as group III, and in addition postoperative intravenous infusion of PGE1 and tissue expansion was performed(n = 10). Flap survival rates of each group were evaluated and compared. The following results were obtained: 1. Survival rates of prefabricated flaps were lower than that of classic axial pattern flaps regardless of using tissue expansion and PGE1 infusion(p < 0.05). 2. In making a comparison between flap with and without PGE1 infusion, survival rates of prefabricated flaps infused with PGE1 were higher than that of flaps without PGE1 infusion. 3. The prefabricated flaps managed with tissue expansion had higher survival rates than that of flaps without using tissue expansion. 4. The survival rates of prefabricated flaps managed in combination with tissue expansion and PGE1 infusion were significantly higher than that of other groups except control group. In conclusion, this study demonstrated the significance of combiring use of tissue expansion and PGE1 infusion in a prefabricated musculocutaneous flaps as a reliable method.
Alprostadil
;
Humans
;
Infusions, Intravenous
;
Myocutaneous Flap
;
Rabbits*
;
Rectus Abdominis
;
Skin
;
Survival Rate
;
Tissue Donors
;
Tissue Expansion