1.A case report of cerebral sparganosis associated with seizure.
Kyung Sik KOH ; Tae Yul CHOI ; Ik YANG ; Woo Suk CHOI ; Sun Yung SHIN ; Hwan Jo SUH
Korean Journal of Infectious Diseases 1993;25(4):393-398
No abstract available.
Seizures*
;
Sparganosis*
2.Toxicological Profiles of Poisonous, Edible, and Medicinal Mushrooms.
Woo Sik JO ; Md Akil HOSSAIN ; Seung Chun PARK
Mycobiology 2014;42(3):215-220
Mushrooms are a recognized component of the human diet, with versatile medicinal properties. Some mushrooms are popular worldwide for their nutritional and therapeutic properties. However, some species are dangerous because they cause toxicity. There are many reports explaining the medicinal and/or toxic effects of these fungal species. Cases of serious human poisoning generally caused by the improper identification of toxic mushroom species are reported every year. Different substances responsible for the fatal signs and symptoms of mushroom toxicity have been identified from various poisonous mushrooms. Toxicity studies of mushroom species have demonstrated that mushroom poisoning can cause adverse effects such as liver failure, bradycardia, chest pain, seizures, gastroenteritis, intestinal fibrosis, renal failure, erythromelalgia, and rhabdomyolysis. Correct categorization and better understanding are essential for the safe and healthy consumption of mushrooms as functional foods as well as for their medicinal use.
Agaricales*
;
Bradycardia
;
Chest Pain
;
Diet
;
Erythromelalgia
;
Fibrosis
;
Functional Food
;
Gastroenteritis
;
Humans
;
Liver Failure
;
Mushroom Poisoning
;
Poisoning
;
Renal Insufficiency
;
Rhabdomyolysis
;
Seizures
3.A Clinical Study of TravogenR and TravocortR / TravogenR Therapy in Superficial Fungal Diseases: Multicenter Trials.
Do Sik SONG ; Byung In RO ; Chin Yo CHANG ; Kang Woo LEE ; Kyung Jin RHIM ; Yong Woo CINN ; Kyung Sool KWON ; chang Jo COH ; Jang Kyu PARK
Korean Journal of Dermatology 1984;22(3):255-262
Isoconazole nitrate is one of the broad-spectrum antimycotic agents recently developed from imidazole derivatives. Authors performed ulticenter trials to evaluate the therapeutic effect of Travogen and Travocort in superficial fungal diseases. In the usual superficial fungal diseases, Travogen was applied 4 weeks. In the inflammatory and eczematoid superficial fungal diseases, Travocort was applied 2 weeks initially and then followed by 2 weeks application of Travogen. One hundred and ninty one patients with superficial fungal diseases were included in this study during g months from December, 1982 to August, 19$3 The obtained results were as follows; The overall cure rate of Travogen and Travocort in each superficial fungal diseases were gl 7g (tinea pedis), 98. L% (tinea cruris), 1ppg, (tinea corporis), 9g. 100% (tinea manus), 1ppg (tinea capitis) and 1pgg (candidiasis) respectively. Trichophyton rubrum(51. 3%), Trichophyton mentagrophytes(29.3g), Tricho -countinue-
Humans
;
Trichophyton
4.In vitro activities of eight antibiotics against methicillin-resistant S. aureus and S. epidermidis strains isolated in Korea.
Woo Hyun CHANG ; Myung Sik CHOI ; Hee Young CHUNG ; Whan Jo SEO ; Tae Yeol CHOI ; Yun Sop CHONG ; Jae Sik KIM ; Sun Sik CHUNG ; Suk Hee HONG
Journal of Korean Medical Science 1988;3(2):45-50
Staphylococcus aureus and Staphylococcus epidermidis strains isolated at eight large medical centers in Korea were examined for methicillin resistance and resistance to eight other antibiotics; cefazolin, cefamandole, cefuroxime, cefoxitin, cefotaxime, moxalactam, penicillin G and vancomycin. Methicillin resistance was found in 296 of 1225 strains (24.2%) of S. aureus and 126 of 348 strains (36.2%) of S. epidermidis. Methicillinresistant strains were isolated from all sources with the frequency of isolation ranging from 11% to 60%. From pleural effusion, throat swab and blood, methicillin-resistant strains of S. aureus were more frequently isolated with statistical significance (Chi-squared test, 95% confidence). Almost all of Methicillin-resistant S. aureus (MRSA) and S. epidermidis (MRSE) strains were multiply resistant to one or more tested eight antibiotics. However only 7(2.4%) of 296 MRSA strains and 2(1.6%) of 126 MRSE strains were resistant to vancomycin. Vancomycin was the most effective antibiotic against staphylococcal isolates as well as MRSA and MRSE.
Anti-Bacterial Agents/*pharmacology
;
Cross Infection/microbiology
;
Drug Resistance, Microbial
;
Humans
;
Korea
;
Staphylococcal Infections/microbiology
;
Staphylococcus aureus/*drug effects/isolation & purification
;
Staphylococcus epidermidis/*drug effects/isolation & purification
5.A Clinical Study on Staphylococcus Aureus Bacteremia.
Hwa Jeong HONG ; Chung Hwan LEE ; Chong Oh PARK ; Il Woo JUNG ; Seung Ho LEE ; Kyung Sik KO ; Koo Yeop KIM ; Hwan Jo SUH
Korean Journal of Medicine 1997;53(3):359-370
OBJECTIVE: Staphylococcus aureus has persisted and is now resurging as an important hospital and community pathogen. Nosocomial infection caused by methicillin-resistant S.aureus(MRSA) is a major problem which may be connected with heavy or prolonged use of antibiotics S.aureus bacteremia caused acute complications, which occasionally resulted in death, and infectious/suppurative complications, which necessitated prolonged antibiotic therapy, sometimes in conjunction with surgery. Therefore, S.aureus bacteremia is a serious medical problem in association with high morbidity and mortality. METHODS: 130 patients with S.aureus bacteremia who were admitted in the Kyung Hee University Hospital from January, 1991 to December, 1994 were analyzed retrospectively. We compared the clinical and laboratory characteristics, and antibiotics resistances between MRSA and MSSA bacteremia and also we evaluated risk factors that contribute to fatal outcome in patients with S.aureus bacteremia. RESULTS: 1) of 130cases, 80 were male and 50 were female. The mean age was 44.5+/-25.1 years. 2) 84(65%) of S.aureus bacteremia were nosocomial and 46(35%) were community-acpuired. The percentage of MRSA stains studied was 55%(71/130) and The percentage of MRSA bacteremia in hospital-acpuired and community-accquired S. aureus bacteremia were 64% (54/84) and 36%(17/46), respectively. Sources of bacteremia were uncertain in 85(65%) with intravascular catheter(20%) and skin wound sites (8%) being the most common sources in remainder(35%) 3) 110(85%) of 130 patients had one or more underlying diseases. Common underlying dieases were cerebrovascular disease(33%), malignancy(17%), Diabetes mellitus(15%), chronic renal failure(8%) and liver cirrhosis(6%). 4) Acute complications occurred in 35 patients and were fatal in 21 5) The risk factors associated with MRSA bacteremia were various severe underlying diseases, vairous invasive procedures, IV catheter-associated infection, hypoalbuminemia, previous use of antibiotics, male sex and old age. 6) The Case fatality rate for patients with S. aureus bacteremia was 18% and those for patients with MRSA and MSSA bactermia were 20% and 12%, respectively. The risk factors that contribute to the increment of mortality rate in patients with S. aureus bacteremia were acute complication, low serum level of total protein, hypoalbuminemia, various invasive procedures and IV catheter-associated infection, 7) In the antibiotic sensitivity test S. aureus was resistant to penicillin in 98.5%, ofloxacin in 73%, cefotaxime in 67%, erythromycin in 58%, aztreonam in 56%, clindamycin in 52%, vancomycin in 0%. 8) In the multiple antibiotic resistance of S. aureus, 43(68%) of MRSA was resistant to more than 10 antibotics, revealing multiply resistant nature of strains, While all but one MSSA was resistant to 1 to 4 antibiotics, one revealing resistance to 8 antibiotics. CONCLUSION: S. aureus bacteremia is a cause of considerable morbidity and mortality in hospitalized patients who especially, exposed to various risk factors. MRSA revealed higher resistance rate to most antibiotics tested and more marked multiply resistant nature than MSSA. But there was no significant difference in case fatality rate between patients with MRSA and MSSA bacteremia.
Anti-Bacterial Agents
;
Aztreonam
;
Bacteremia*
;
Catheter-Related Infections
;
Cefotaxime
;
Clindamycin
;
Coloring Agents
;
Cross Infection
;
Drug Resistance, Microbial
;
Erythromycin
;
Fatal Outcome
;
Female
;
Humans
;
Hypoalbuminemia
;
Liver
;
Male
;
Methicillin Resistance
;
Methicillin-Resistant Staphylococcus aureus
;
Mortality
;
Ofloxacin
;
Penicillins
;
Retrospective Studies
;
Risk Factors
;
Skin
;
Staphylococcus aureus*
;
Staphylococcus*
;
Vancomycin
;
Wounds and Injuries
6.A Clinical Review of Geriatric Anesthesia - an Analysis of 601 Cases .
Kang Woo LEE ; Man Sik YANG ; Yoon Gie MIN ; Byung Jo CHOI
Korean Journal of Anesthesiology 1981;14(4):443-452
A total of 601 anesthesias given to the patients over age 60 who were admitted to Han Gang Sung Shim Hospital during the period from Jan. 1976 to Dec. 1980, were subjected to this clinical review. 1) Of the total 15,609 cases, 601 cases(3.8%) were over 60 years of age consisting of 315 male(52.4%) and 286 female(47.6%). 2) Among the 601 geriatric patients, 453 cases were 60~69 years of age(75.4%), 128 cases were 70~79 years of age(21.3%) and 20 cases were over 80 years of age(3.3%). 3) In the surgical group, 358 cases(59.7%) were general surgery, 120 cases(20.0%) were orthopedic surgery, 34 cases(5.6%) were urology, 20 cases(3.3%) were gynecology respectively. 4) The techniques of anesthesia were 545 cases(90.7%) of general anesthesia, 22 cases(3.7%) of spinal anesthesia and 17 cases(2.8%) of axillary block. 5) Anesthetics were diethly-ether 24 cases(36.3%) and halothane 22 cases(33.3%) in 1976. But there were 5 diethly-ether cases(0.3%) and 120 halothane cases(91.6%) in 1980. 6) For the duration of anesthesia, 81 cases(13%) were within 1 hour, 238 cases(39.6%) within 2 hours, 156 cases(26.0%) within 3 hours and 21 cases over 5 hours. 7) In the classification of physical status of the geriatric patients, 42 cases(7.0%) were class l, 201 cases(33.2%) were class ll, 109 cases (18.1%) were class lll and 8 cases(1.3%) were class lV. 8) Emergency cases were 223 cases(37.1%) and 378 cases(62.9%) were elective. 9) The findings of preoperative chest X-rays revealed that 227 cases(48.8%) were within normal limits, 56 cases(12.0%) had hypertensive heart disease, 24 cases(5.1%) had senile fibrosis, 22 cases(5.1%) had unstabilized tuberculosis and 14 cases(3%) had pneumonis. 10) In the preoperative R.K.G., which covered 50% of the patients, 115 cases(38.3%) were within normal limit, 41 cases(13.6%) showed L.V.H., 30 cases(10.0%) had sinus bradycardia, 13 cases (4.3%) had myocardial lschemia and 7 cases(2.3%) had R.B.B.B. 11) Post-operative mortality rate was 5.8% in 1976, 4.0% in 1977, 3.6% in 1978 and 2.1% in 1980, and over all mortality rate was 3.1%.
Anesthesia*
;
Anesthesia, General
;
Anesthesia, Spinal
;
Anesthetics
;
Bradycardia
;
Classification
;
Emergencies
;
Fibrosis
;
Gynecology
;
Halothane
;
Heart Diseases
;
Humans
;
Mortality
;
Orthopedics
;
Thorax
;
Tuberculosis
;
Urology
7.Double-blind, Placebo-controlled, Multi-center Study for Therapeutic Effects of Mountain Panax Ginseng C.A. Meyer Extract in Men with Erectile Dysfunction: a Preliminary Report.
Hong Sik KIM ; Seung Hyo WOO ; Shunghwan JO ; Eun Joo HAHN ; Nae Young YOUN ; Hyung Lae LEE
Korean Journal of Andrology 2006;24(2):84-88
PURPOSE: We investigated the effect of 100-year-old mountain ginseng(Panax ginseng C.A. Meyer, PG-CAM) extract on patients with erectile dysfunction(ED). MATERIALS AND METHODS: A total of 35 patients with ED(23 patients in PG-CAM administration group, 12 in placebo group) were enrolled in this double-blind study. The drug was administered for 12 weeks. Before and after administration, patients took the self-administered IIEF-5 questionnaire and were tested for serum hormone levels(testosterone, LH, FSH, estradiol), complete blood count, liver and renal function test, and urinalysis. RESULTS: The IIEF-5 scores for the placebo group were 19.7+/-2.3 and 19.9+/-3.6 before and after treatment, respectively. For all patients taking PG-CAM, IIEF-5 scores increased 18.1+/-5.6 to 20.2+/-4.5. For those patients with initial scores below 17, IIEF-5 scores increased from 12.4+/-6.2 to 19.7+/-6.7. These results indicate that PG-CAM may increase erectile function in ED patients, particularly those with poor erection. No changes were detected in hormonal levels or blood tests. No toxic side effect were reported. CONCLUSIONS: IIEF-5 score improved significantly in ED patients treated with PG-CAM, suggesting that PG-CAM extract could be a treatment candidates for ED.
Blood Cell Count
;
Double-Blind Method
;
Erectile Dysfunction*
;
Hematologic Tests
;
Humans
;
Liver
;
Male
;
Panax*
;
Penis
;
Surveys and Questionnaires
;
Urinalysis
8.Double-blind, Placebo-controlled, Multi-center Study for Therapeutic Effects of Mountain Panax Ginseng C.A. Meyer Extract in Men with Erectile Dysfunction: a Preliminary Report.
Hong Sik KIM ; Seung Hyo WOO ; Shunghwan JO ; Eun Joo HAHN ; Nae Young YOUN ; Hyung Lae LEE
Korean Journal of Andrology 2006;24(2):84-88
PURPOSE: We investigated the effect of 100-year-old mountain ginseng(Panax ginseng C.A. Meyer, PG-CAM) extract on patients with erectile dysfunction(ED). MATERIALS AND METHODS: A total of 35 patients with ED(23 patients in PG-CAM administration group, 12 in placebo group) were enrolled in this double-blind study. The drug was administered for 12 weeks. Before and after administration, patients took the self-administered IIEF-5 questionnaire and were tested for serum hormone levels(testosterone, LH, FSH, estradiol), complete blood count, liver and renal function test, and urinalysis. RESULTS: The IIEF-5 scores for the placebo group were 19.7+/-2.3 and 19.9+/-3.6 before and after treatment, respectively. For all patients taking PG-CAM, IIEF-5 scores increased 18.1+/-5.6 to 20.2+/-4.5. For those patients with initial scores below 17, IIEF-5 scores increased from 12.4+/-6.2 to 19.7+/-6.7. These results indicate that PG-CAM may increase erectile function in ED patients, particularly those with poor erection. No changes were detected in hormonal levels or blood tests. No toxic side effect were reported. CONCLUSIONS: IIEF-5 score improved significantly in ED patients treated with PG-CAM, suggesting that PG-CAM extract could be a treatment candidates for ED.
Blood Cell Count
;
Double-Blind Method
;
Erectile Dysfunction*
;
Hematologic Tests
;
Humans
;
Liver
;
Male
;
Panax*
;
Penis
;
Surveys and Questionnaires
;
Urinalysis
9.Three Cases of Primary Ovarian Pregnancy.
Hyuk Woo LEE ; Sang Kug BYUN ; Jae Chul PARK ; Yong Ho JO ; Eui Sik JUNG
Korean Journal of Obstetrics and Gynecology 2002;45(11):2081-2086
Primary ovarian pregnacy is a rare form of ectopic pregnacy of which an estimated overall incidence is highly variable, but improved diagnosis of acute hemoperitoneum of ovarian may reveal a higher incidence than reported earlier. Ovarian pregnancy is uaually accompanied with the rupture of the ovary and massive hemoperitoneum. It usually presents with abdominal pain, menstural irregularities, vaginal bleeding, a palpable adnexal mass and other symptoms which are very similar to those of tubal ectopic pregnacy and hemorrhgic corpus luteum cysts. Risk factors to ovarian pregnancy include a history of pelvic inflammatory disease (PID), prior pelvic surgery, and use of an intrauterine contraceptive devices (IUD). We have experienced three cases of ovarian pregnancy, which are presented with a brief review of the literature.
Abdominal Pain
;
Diagnosis
;
Female
;
Hemoperitoneum
;
Incidence
;
Intrauterine Devices
;
Ovarian Cysts
;
Ovary
;
Pelvic Inflammatory Disease
;
Pregnancy
;
Pregnancy, Ectopic*
;
Risk Factors
;
Rupture
;
Uterine Hemorrhage
10.Three Cases of Primary Ovarian Pregnancy.
Hyuk Woo LEE ; Sang Kug BYUN ; Jae Chul PARK ; Yong Ho JO ; Eui Sik JUNG
Korean Journal of Obstetrics and Gynecology 2002;45(11):2081-2086
Primary ovarian pregnacy is a rare form of ectopic pregnacy of which an estimated overall incidence is highly variable, but improved diagnosis of acute hemoperitoneum of ovarian may reveal a higher incidence than reported earlier. Ovarian pregnancy is uaually accompanied with the rupture of the ovary and massive hemoperitoneum. It usually presents with abdominal pain, menstural irregularities, vaginal bleeding, a palpable adnexal mass and other symptoms which are very similar to those of tubal ectopic pregnacy and hemorrhgic corpus luteum cysts. Risk factors to ovarian pregnancy include a history of pelvic inflammatory disease (PID), prior pelvic surgery, and use of an intrauterine contraceptive devices (IUD). We have experienced three cases of ovarian pregnancy, which are presented with a brief review of the literature.
Abdominal Pain
;
Diagnosis
;
Female
;
Hemoperitoneum
;
Incidence
;
Intrauterine Devices
;
Ovarian Cysts
;
Ovary
;
Pelvic Inflammatory Disease
;
Pregnancy
;
Pregnancy, Ectopic*
;
Risk Factors
;
Rupture
;
Uterine Hemorrhage