Secondary osteoarthritis of hip joints is a common disease and is frequently followed by chronic sublexation and dislocation. Twenty four case of the secondary osteoarthritis associated with chronic subluxation and dislocation of the hip joints were evaluated with plain radiography and computed tomography. We retrospectively analyzed 1) the ossification and calcification of the acetabular labrum, 2) the thickeness of the quadrilateral plate of the ilium, and 3) anteroposterior diameter of the acetabulum. The changes of the hip joints in subluxation (n=14) revealed ossification of the acetabular labrum in 12 cases (86%), thickening of the quadrilateral plate of the ilium in 11 cases (78%) but anteroposterior diameter of the acetabulum was not changed. The changes of the hip joints in dislocation (n=10) revealed no evidence of the ossification of the acetabular labrum, thickening of the quadrilateral plate of the ilium in 10 cases (100%) and decreased anteroposterior diameter of the acetabulum. We conclude that CT findings of subluxation and dislocation of the hip joints can be helpful in the evaluation of the secondary osteoarthritis of the hip joints.
Acetabulum ; Dislocations* ; Hip Joint* ; Hip* ; Ilium ; Joints ; Osteoarthritis ; Osteoarthritis, Hip ; Radiography ; Retrospective Studies

The recorded cases of ileovesical fistula are surprisingly few. However, when encountered, they present an interesting problem which commands the attention of urologist. Ileovesical fistula due to malignant lymphoma is a rare disease and usually first manifested by a long period of urinary symptom. We report a case of ileovesical fistula due to malignant lymphoma, diffuse, poorly differentiated, lymphocytic type, in sixty-four-year-old male patient with the brief review of literature.
Fistula* ; Humans ; Lymphoma* ; Male ; Rare Diseases

Adenoid cystic carcinoma is a rare disease of which incidence is 10-15 % of bartholins gland carcinoma. The clinical presentation is characterized by a vulval mass that existed for a prolonged period to the onset of symptoms, usually infection, pain, and burningsensation Histologically, this tumor is characterized by cribriform pattern cell growing and perineural invasion. The obtaining of clear surgical margins is the most important aspect of treatment. Here we report a case of adenoid cystic carcinoma of the Bartholins gland with a brief review of literature.
Adenoids* ; Carcinoma, Adenoid Cystic* ; Incidence ; Rare Diseases

Alcohol has been used as sedatives historically. The effect of alcohol on sleep is different according to its dose, timing of ingestion, and drinking frequency. Sleep problems may play a role in the development and course of alcohol-related disorders. Insomnia in alcohol-dependent patients is common and early treatment of insomnia may reduce the rate of relapse. Sleep apnea, restless legs syndrome, periodic limbs movement disorder, and altered circadian rhythm may be more frequent in this patients. Management of sleep and alcohol problems is important in treating alcohol-related disorder and sleep disorders, respectively.
Alcohol-Related Disorders ; Circadian Rhythm ; Drinking ; Eating ; Extremities ; Humans ; Hypnotics and Sedatives ; Movement Disorders ; Recurrence ; Restless Legs Syndrome ; Sleep Apnea Syndromes ; Sleep Wake Disorders ; Sleep Initiation and Maintenance Disorders

No abstract available.
Hepatitis B* ; Hepatitis* ; Thyroid Diseases* ; Thyroid Gland*

BACKGROUND: Wound healing process is a tissue response to trauma which leads to tissue repair through complex biological stages. Sevoflurane is a widely used inhalation anesthetic for surgery, but there has been no study about its effect on wound healing process. This study was undertaken to evaluate the effect of sevoflurane on wound healing process. METHODS: Male Sprague-Dawley rats (200-300 g) were used. Two circular full-thickness skin defects of 8 mm in diameter were made on dorsum of rats. After wound formation, the animals were divided into 4 groups: 1, 2, 4, 8 hr exposure to sevoflurane, respectively. Wound sizes and regional blood flow around the wounds were measured. The expression of basic fibroblast growth factor (bFGF), transforming growth factor beta1 (TGFbeta1), collagen 1, and collagen 3 mRNA were detected 7 days after wound formation by real-time reverse transcriptase-polymerase chain reaction (RT-PCR). RESULTS: Wound size was significantly increased in 8 hr group at 3 and 7 days after wound formation. Regional blood flow was significantly decreased in 4 hr and 8 hr groups at 3 days after wound formation. The bFGF, collagen 1 and 3 mRNA expressions were significantly decreased in 8 hr exposure group. CONCLUSIONS: These results suggest that sevoflurane exposure influences the regional blood flow, wound size, expression of bFGF, and production of collagen 1 and 3 during the wound healing process.
Animals ; Collagen ; Fibroblast Growth Factor 2 ; Humans ; Inhalation ; Male ; Methyl Ethers ; Rats ; Rats, Sprague-Dawley ; Regional Blood Flow ; RNA, Messenger ; Skin ; Transforming Growth Factor beta1 ; Wound Healing

Near-infrared (NIR) fluorescence imaging is a promising method for image-guided surgery, providing robust functional images with relatively good cost-effectiveness. A cyanine vital dye indocyanine green (ICG) is a safe NIR fluorophore emitting 800~840 nm of light and has been used in numerous surgical procedures. The technique has been applied to lymph node navigation of gastric cancer surgery with an expectation of better visualization of lymphatic structures without any risk of radio-hazard compared with a “dual method” using both vital dyes and radioisotopes. Given the characteristics of ICG, such as fast distribution and quenching effect, diluted concentrations, such as 0.05~0.1 mg/ml, are thought to be optimal for sentinel node navigation. Injection into the subserosal layer is feasible; however, endoscopic submucosal injection has advantages of improved accuracy of the injection site and feasibility of injection one day prior to surgery; these advantages are preferred by some investigators due to a smaller number of sentinel nodes compared with injection in the operation theatre. The technology requires evaluation of the sensitivity and specificity, as well as the non-inferiority, compared with the dual method in a large cohort for justification as a safe node navigation method.
Cohort Studies ; Coloring Agents ; Fluorescence* ; Humans ; Indocyanine Green* ; Lymph Nodes* ; Methods ; Optical Imaging ; Radioisotopes ; Research Personnel ; Sensitivity and Specificity ; Sentinel Lymph Node Biopsy ; Stomach Neoplasms* ; Surgery, Computer-Assisted

No abstract available.
Korea*

BACKGROUND: A number of reports have stressed the usefulness of cell kinetic estimations as an aid in the prognostic and diagnostic classification of malignant lymphoma. But very limited information is available concerning cell cycle distirbutions in cutaneous lymphoid infiltrate, although a number of these conditions present tremendous problems in diagnosis and management. OBJECTIVE: The purpose of this study is to evaluate the proliferative activities in various cutaneous lymphoid infiltrates and its usefulness in diagnosis or foretelling a prognosis. METHODS: Fifty two arehival biopsy specimens were studies. These included cases of peripheral T-cell lymphoma, lichen planus, lupus erythematosus, polymorphous light eruptions, and pseudolymphomas such as insect bite, lymphomatoid papulosis, and other lymphocytoma cutis. Ki-67 was identified by immunoperoxidase technique using MIB1, a monoclonal antibody that recognizes a fixation and embedding resistant epitope on the Ki-67 protein. RESULTS: Higher Ki-67 positive rates were observed in high grade angiocentric T-cell lymphomas, which was helpful in differentiating from benign disease. In two cases of lymphomas which Ki-67 positive rate were more than 80 percent despite of minimal lymphoid infiltrate in skin biopsy specimen, evaluation of Ki-67 expression was profoundly helpful in diagnosing them as malignancies. CONCLUSION: Use of this technique was useful in evaluation of proliferative activity of cutaneous lymphoid infiltrate. In some cases, use of this technique may aid us in differential diagnosis of malignant lymphoma from benign chronic inflammatory disease of the skin.
Biopsy ; Cell Cycle ; Classification ; Diagnosis ; Diagnosis, Differential ; Immunoenzyme Techniques ; Insect Bites and Stings ; Lichen Planus ; Lymphoma ; Lymphoma, T-Cell ; Lymphoma, T-Cell, Peripheral ; Lymphomatoid Papulosis ; Prognosis ; Pseudolymphoma ; Skin

BACKGROUND: A number of reports have stressed the usefulness of cell kinetic estimations as an aid in the prognostic and diagnostic classification of malignant lymphoma. But very limited information is available concerning cell cycle distirbutions in cutaneous lymphoid infiltrate, although a number of these conditions present tremendous problems in diagnosis and management. OBJECTIVE: The purpose of this study is to evaluate the proliferative activities in various cutaneous lymphoid infiltrates and its usefulness in diagnosis or foretelling a prognosis. METHODS: Fifty two arehival biopsy specimens were studies. These included cases of peripheral T-cell lymphoma, lichen planus, lupus erythematosus, polymorphous light eruptions, and pseudolymphomas such as insect bite, lymphomatoid papulosis, and other lymphocytoma cutis. Ki-67 was identified by immunoperoxidase technique using MIB1, a monoclonal antibody that recognizes a fixation and embedding resistant epitope on the Ki-67 protein. RESULTS: Higher Ki-67 positive rates were observed in high grade angiocentric T-cell lymphomas, which was helpful in differentiating from benign disease. In two cases of lymphomas which Ki-67 positive rate were more than 80 percent despite of minimal lymphoid infiltrate in skin biopsy specimen, evaluation of Ki-67 expression was profoundly helpful in diagnosing them as malignancies. CONCLUSION: Use of this technique was useful in evaluation of proliferative activity of cutaneous lymphoid infiltrate. In some cases, use of this technique may aid us in differential diagnosis of malignant lymphoma from benign chronic inflammatory disease of the skin.
Biopsy ; Cell Cycle ; Classification ; Diagnosis ; Diagnosis, Differential ; Immunoenzyme Techniques ; Insect Bites and Stings ; Lichen Planus ; Lymphoma ; Lymphoma, T-Cell ; Lymphoma, T-Cell, Peripheral ; Lymphomatoid Papulosis ; Prognosis ; Pseudolymphoma ; Skin