No abstract available.

No abstract available.
Scalp* ; Superficial Back Muscles*

No abstract available.
Hand*

Trichorhinophalangeal syndrome (TRPS) was first described in 1966 by Giedion. It is a rare genetic disease and divided into two groups : TRPS type I and TRPS type II. TRPS type I is an autosomal dominant inherited disorder, defined by three characteristic findings : first, sparsely distributed brittle and slow-growing scalp hair, second, a bulbous pear-shaped nose with an elongated philtrum, third brachydactyla with angular deformities. The characteristic radiological features of the hands include cone shaped epiphysis of the proximal interphalangeal joints. Most TRPS type II is sporadic and shows multiple exosteosis, mental retardation and microcephaly in addition to the three chracteristic findings of TRPS type I . A 20-year-old female visited our department for the evaluation of her sparse, slow-growing scalp hair. She also had a bulbous pearshaped nose, ulnar deviated fingers and shortened both hallux. Some relatives of patients show similar symptoms of scalp hair. A Radiologic aly, histopathologic aly and chromosomal study were done, and we established the diagnosis, TRPS type I.
Congenital Abnormalities ; Diagnosis ; Epiphyses ; Female ; Fingers ; Hair ; Hallux ; Hand ; Humans ; Intellectual Disability ; Joints ; Lip ; Microcephaly ; Nose ; Scalp ; Young Adult

No abstract available.
Pregnancy*

This study was undertaken to compare by Atomic Force Microscope the effects of various finishing and polishing instruments on surface roughness of filling and veneering composite resins. Seven composite resins were studied : Silux Plus (3M Dental Products, U.S.A.), charisma (Heraeus Kulzer, Germany), Prisma THP (L.D.Caulk, Dentsply, U.S.A.), Photoclearfil (Kuraray, Japan), Cesead (Kuraray, Japan), Thermoresin LC (GC, Japan), Artglass (Heraeus Kulzer, Germany), samples were placed and polymerized in holes (2mm thick and 8.5mm in diameter) machined in Teflon mold under glass plate, ensuring excess of material and moulded to shape with polyester matrix strip, Except control group (polyester mztrix strip), all experimental groups were finished and polishied under manufacturer's instructions. The finishing and polishing procedure were : carbide bur (E.T. carbide set 4159, Komet, Germany), diamond bur (composite resin polishing bur set, GC, Japan), aluminum-oxide disc (Sof-Lex Pop-On, 3M Dental Products, U.S.A.), diamond-particle disc (Dia-Finish, Renfert Germany), white stone bur & rubber point(composite finishing kit, EDENTA, Swiss), respectively. Each specimens were evaluated for the surface roughness with Atomic Force Microscope (AutoProbe CP, Park Scientific Instruments, U.S.A.) under contact mode and constant height mode. The results as follows : 1. Except Thermoresin LC, all experimental composite resin groups showed more rougher than control group after finishing and polishing(p<0.1). 2. A surface as smooth as control group was obtained by Al2O3 disc all filling composite resin groups except Charisma and all veneering composite resin groups except Thermoresin LC(p<0.05). 3. In case of Thermoresin LC, there were no statistically significant differences before and after finishing and polishing(p>0.1). 4. Carbide bur, diamond bur showed rough surfaces in all composite resin groups, so these were inappropriate for the final poslishing instruments.
Bisphenol A-Glycidyl Methacrylate ; Composite Resins* ; Dental Instruments ; Fungi ; Glass ; Polyesters ; Polymers ; Polytetrafluoroethylene ; Rubber

Internuclear ophthalmoplegia (INO) is characteristic of lesions of the medial longitudinal fasciculus (MLF) between the third and sixth cranial nerve nucleus. Bilateral INO is due to bilateral lesions of MLF. We present here one case of bilateral INO in tuberculous meningitis.
Abducens Nerve ; Ocular Motility Disorders* ; Tuberculosis, Meningeal

The definition of tissue engineering by Langer is "an interdisciplinary field that applies the principles of engineering and the life sciences toward the development of biological substitutes that restore, maintain, or improve tissue function." This technology has achieved remarkable growth in the past 20 years, provoked by its potential role in regenerating new tissues and naturally healing injured or diseased organs. Although stem cells are still in the research phase, their pluripotency and unlimited capacity for self-renewal may enable significant advances for reconstructive and cosmetic procedures with this engineering technology. This article aims at outlining the principles of tissue engineering and its recent advances and future prospects.
Biological Science Disciplines ; Reconstructive Surgical Procedures ; Regenerative Medicine ; Stem Cells ; Tissue Engineering* ; Tissue Scaffolds

No abstract available.
Progeria*

Previous successful results of neocartilage formation using tissue engineering technique in immunocompromised nude mouse xenograft model were reported. For clinical application, autogenous cell is preferrable to allogenic or xenogenic cell for circumvention of immune rejection. This study evaluates the feasibility of producing a engineered cartilage using autogenous chondrocytes. Chondrocytes were isolated from the auricular cartilage of New Zealand White rabbit and seeded onto PGA polymer coated with polylactic acid in round pattern(diameter 0.7 cm, thickness 0.1 cm) at a concentration 7 x 10(7) chondrocytes per cm3. Each Autogenous Cell-polymer constructs were implanted subcutaneously into the left side of dorsum of twelve rabbits. Polymer templates not containg cells were implanted into the right side as a control. Twelve rabbits were sacrificed at the following intervals: 5 rabbits at nine weeks, 7 rabbits at twelve weeks New autogenous cartilage formation which retained the approximate dimensions of original round polymer template in 11 of 12 cell seeded implants. Histological examination using hematoxyline and eosin stain revealed vast majority of implants developed into mature cartilage. This study opens up the possibility of autologus cell transplant to construct autogenous cartilge.
Animals ; Cartilage* ; Chondrocytes* ; Ear Cartilage ; Eosine Yellowish-(YS) ; Hematoxylin ; Heterografts ; Mice ; Mice, Nude ; New Zealand ; Polymers ; Rabbits ; Tissue Engineering ; Transplants