For the patients suffering from extensive deep vein thrombosis (DVT), the placement of an inferior vena cava (IVC) filter in conjunction with anticoagulant therapy has been used to prevent pulmonary embolisms. However, for the patients who anticoagulant is contraindicated or if this is complicated, the use of an IVC filter without concurrent anticoagulation may become the sole treatment for pulmonary embolisms. In this situation, the thrombi trapped in the IVC filter may cause significant clinical problems. We report here on a case of IVC filter thrombosis that was successfully treated by aspiration thrombectomy after placing another filter proximal to the previous filter.
Humans ; Pulmonary Embolism ; Thrombectomy* ; Thrombosis* ; Vena Cava Filters* ; Vena Cava, Inferior* ; Venous Thrombosis

5-fluorouracil(5-FU) and its derivatives have been prescribed preoperatively in Korea for oral administration to patients with gastric cancer as an adjuvant therapy. Since the conditions of the patients after gastrectomy may be different and thereby influence the absorption of 5-fluorouracil, we were interested in the pharmacokinetic changes of 5-fluorouracil absorption after gastric resection. Fourteen of 40 gastric cancer patients, who underwent radical subtotal gastrectomy with D2 lymphnode dissection for gastric cancer, were selected at Ewha Womans University Mok-Dong Hospital from May 1996 to December 1996. The plasma concentrations of 5-fluorouracil were determined before oral administration of 5-FU(500 mg/M2) at 15-min intervals for two hours, and then at 30-min intervals for two hours after oral administration during the pre- and the post-operative periods. High pressure liquid chromatography was used to determine the plasma concentrations of 5-FU. The pharmacokinetic indices included the area under the curve (AUC), the peak concentration (Cmax), and the time to peak concentration (Tmax). The mean postoperative AUC for 5-FU was 25.8+/-14.8% of the mean preoperative AUC, which was a significant decrease in the amount of 5-FU absorption postoperatively. The mean postoperative Cmax was 33.4+/-30.2% of the mean preoperative Cmax, which also meant a significant decrease of the peak concentration postoperatively. The Tmax of most patients were delayed postoperatively, but there was no significant change statistically. In conclusion, we found that the amount of absorbed 5-FU, as calculated by the AUC and the Cmax, significantly decreased after a subtotal gastrectomy by as much as 75 percent compared to the preoperation. Hence, it may be necessary to increase the dose of 5-FU after a subtotal gastrectomy by more than 75% of the preoperative dose. The subtotal gastrectomy did not have a significant effect on the absorptive velocity of 5-FU.
Absorption* ; Administration, Oral ; Area Under Curve ; Chromatography, Liquid ; Female ; Fluorouracil* ; Gastrectomy* ; Humans ; Korea ; Pharmacokinetics ; Plasma ; Stomach Neoplasms

5-fluorouracil(5-FU) and its derivatives have been prescribed preoperatively in Korea for oral administration to patients with gastric cancer as an adjuvant therapy. Since the conditions of the patients after gastrectomy may be different and thereby influence the absorption of 5-fluorouracil, we were interested in the pharmacokinetic changes of 5-fluorouracil absorption after gastric resection. Fourteen of 40 gastric cancer patients, who underwent radical subtotal gastrectomy with D2 lymphnode dissection for gastric cancer, were selected at Ewha Womans University Mok-Dong Hospital from May 1996 to December 1996. The plasma concentrations of 5-fluorouracil were determined before oral administration of 5-FU(500 mg/M2) at 15-min intervals for two hours, and then at 30-min intervals for two hours after oral administration during the pre- and the post-operative periods. High pressure liquid chromatography was used to determine the plasma concentrations of 5-FU. The pharmacokinetic indices included the area under the curve (AUC), the peak concentration (Cmax), and the time to peak concentration (Tmax). The mean postoperative AUC for 5-FU was 25.8+/-14.8% of the mean preoperative AUC, which was a significant decrease in the amount of 5-FU absorption postoperatively. The mean postoperative Cmax was 33.4+/-30.2% of the mean preoperative Cmax, which also meant a significant decrease of the peak concentration postoperatively. The Tmax of most patients were delayed postoperatively, but there was no significant change statistically. In conclusion, we found that the amount of absorbed 5-FU, as calculated by the AUC and the Cmax, significantly decreased after a subtotal gastrectomy by as much as 75 percent compared to the preoperation. Hence, it may be necessary to increase the dose of 5-FU after a subtotal gastrectomy by more than 75% of the preoperative dose. The subtotal gastrectomy did not have a significant effect on the absorptive velocity of 5-FU.
Absorption* ; Administration, Oral ; Area Under Curve ; Chromatography, Liquid ; Female ; Fluorouracil* ; Gastrectomy* ; Humans ; Korea ; Pharmacokinetics ; Plasma ; Stomach Neoplasms

Keloids are benign fibrcus growths which extend beyond the original wound and rarely regress. Available methods of treatment include surgical excision, radiotherapy, intralesional steroid injection, cryotherapy, systemie. chemotherapy, zinc tape strapping, pressure, silicon gel and combined therapy. Postoperative irradiation is a useful and effective method of eradication or prevent.ion of keloid. We describe two cases of the prevention of keloids associated with postoperative irradiation.
Cryotherapy ; Drug Therapy ; Keloid* ; Radiotherapy ; Silicone Gels ; Wounds and Injuries ; Zinc

Osteochondroma is the most common benign bone tumor which commonly occurs in the metaphysis of the long bones such as proximal humerus, tibia, and distal femur. It is rarely found in bones of the foot. Although they are benign lesions, when they occur in the foot, they are typically identified earlier than other regions because of the low proliferation of subcutaneous tissue in the region and may cause symptoms. We experienced a rare case of osteochondroma in a 60-year-old male which cause pain and swelling of the fourth toe.
Femur ; Foot ; Humans ; Humerus ; Male ; Middle Aged ; Osteochondroma ; Subcutaneous Tissue ; Tibia ; Toes

PURPOSE: The purpose of this study was to evaluate the clinical results of the old Achilles tendon rupture treated with modified flexor hallucis longus (FHL) tendon transfer. MATERIALS AND METHODS: Seventeen patients with old Achilles tendon rupture treated with modified FHL tendon transfer between March 2004 and February 2008 were enrolled in this study. Technically FHL was pass through the distal portion of the ruptured tendon instead of the drilled hole made on the calcaneus. The mean age of the patients was 37 years (range, 22~67 years), mean follow-up period was 28 months (range, 12~30 months). Patients' subjective satisfaction, calf circumferential diameter, range of motion of ankle and AOFAS ankle-hind foot score and Arner-Lidholm score was evaluated. RESULTS: The average gap between the ruptured tendon was 52 mm (range, 47~56 mm). The AOFAS score improved from 47 pre-operatively to 91 points at the last follow-up. Sixteen patients were satisfied with the result free from discomfort, a patient had mild discomfort who had DM. fourteen patients had decreased range of motion less than 5 degrees while 2 patients had more than 7 degrees decrease compared to the intact side but had no discomfort in daily activities. Nine patients had less than 1 cm calf circumferential diameter difference and 7 patients had 1 to 3 cm diameter difference compared to the intact side. One who had more than 3 cm diameter difference had deteriorated muscle strength. CONCLUSION: Modified FHL tendon transfer can be a useful technique for the treatment of old Achilles tendon rupture when the gap is with large gap placed too proximal.
Achilles Tendon ; Animals ; Ankle ; Calcaneus ; Follow-Up Studies ; Foot ; Humans ; Mandrillus ; Muscles ; Range of Motion, Articular ; Rupture ; Tendon Transfer ; Tendons

Background and Objectives: Few studies have been reported on the strains that cause postoperative infection after chronic otitis media (COM) surgery. This study examined the direction of empirical antibiotics selection for patients with postoperative infection.Subjects and Method This was a retrospective study of 33 patients who were admitted for antibiotics therapy after suffering intractable post-operative infection of COM surgery at Chonnam National University Hospital from 2011 to 2021. Demographic data and microbial culture results of pre-operation and post-operative infection, as well as selected antibiotics for different time periods were evaluated. Results: Most common pathologic organisms responsible for post-operative infection were Methicillin-resistant Staphylococcus aureus (MRSA) (45.5%) and Ciprofloxacin-resistant Pseudomonas aeruginosa (CRPA) (12.1%). Interestingly, there were only three cases where pre- and post-operative culture tests were the same, testing positive for two MRSA and one CRPA. The antibiotics selected as empirical antibiotics for postoperative infection were ceftazidime (48.5%) and vancomycin (27.3%). The rate of the cases where the selected empirical antibiotic was sensitive to the strain was 63.6%, and the rate of changing the antibiotics according to the microbial culture test result was 39.4%. Conclusion The strains cultured from the otorrhea of post-operatively infected patients had a very high ratio of drug-resistant strains and were different from the strains cultured from the otorrhea before surgery. Therefore, a microbial culture test is essential when an infection occurs after surgery, and regardless of the preoperative culture test results, patients with intractable postoperative infections should be treated with empirical vancomycin.

Child ; Dental Arch ; Diagnosis ; Facial Asymmetry ; Follow-Up Studies ; Humans ; Jaw Relation Record ; Mandible ; Parents ; Splints ; Temporomandibular Joint

Esthesioneuroblastoma, Olfactory ; Humans ; Maxillary Sinus ; Nasal Cavity ; Neural Plate ; Olfactory Mucosa ; Radiotherapy

Right atrial aneurysm is a rare abnormality of unknown origin. Approximately half of patients with right atrial aneurysm show no symptoms. Right atrial aneurysm is usually detected by chance at any time between fetal and adult life and can be associated with atrial arrhythmia and systemic embolism. The diagnosis of right atrial aneurysm can be established with echocardiography, computed tomography (CT) or magnetic resonance imaging (MRI). Because of thromboembolic risk, aneurysmectomy is usually recommended. We review the case report of a 69-year-wold woman with right atrial appendiceal aneurysm, whose diagnosis was established by echocardiography and CT angiography.
Adult ; Aneurysm ; Angiography ; Arrhythmias, Cardiac ; Echocardiography ; Echocardiography, Transesophageal ; Embolism ; Female ; Humans ; Magnetic Resonance Imaging