Background: Insulin is known to act as second effector that provides potassium transfer from extracellular fluid to intracellular fluid, thus causing hypokalemia and arrythmia. We evaluated the effect of magnesium sulfate treatment on hemodynamics and serum potassium concentration, induced by continuous infusion of regular insulin solution in rabbits. Method: Twenty-four rabbits were divided into four groups for the experiment. Group I was given intravenouse injection of 5 ml of normal saline and continuous dripping of 7.5 U of RI. Group II was pretreated with 30 mg/kg of magnesium sulfate, followed by continuous dripping of 7.5 U of RI. Group III was given 5 ml of normal saline and 15 U of RI. And Group IV was administered 15 U of RI after 30 mg/kg of magnesium sulfate pretreatment. Venouse blood sampling was done before pretreatment, and after 5, 30, 60 and 120 minutes respectively. Heart rate and arterial blood pressure were taken at the same intervals. Result: 1) There was no significant change in serum potassium concentration in groups injected with 7.5 units of RI respectively (groups I and II), regardless of magnesium pretreatment. But in groups injected with 15 units of RI, the group that was not pretreated with magnesium (Groups III) showed a decrease in serum potassium concentration from 3.39+/-0.57 Eq/L to 2.29+/-0.71 mEq/L, while the concentration in the pretreated group (Group IV) decreased more significantly from 3.35+/-0.50 mEq/L to 1.81+/-0.41 mEq/L. 2) Pulse rate did not change significantly in groups that received continuous infusion of 7.5 units of RI (groups I and II) regardless of magnesium pretreatment, but increased significantly in groups injected with 15 units of RI (groups III and IV), pretreated or not. The pretreated group (group IV) had a more significant rise in pulse rate compared with the group that was not pretreated (group III). 3) In all of the groups, those pretreated with magnesium (groups II and IV) and those not pretreated (groups I and III), there was no significant change in systolic and diastolic blood pressures. Nor was arrhythmia detected. Conclusion: The above results indicate that while magnesium sulfate pretreatment at 30 mg/kg with insulin infusion affects serum potassium concentration, has an antiarrhythmic effect, and may induce tachycardia, it does not have any significant effect on blood pressure.
Arrhythmias, Cardiac ; Arterial Pressure ; Blood Pressure ; Extracellular Fluid ; Heart Rate ; Hemodynamics* ; Hypokalemia ; Insulin ; Intracellular Fluid ; Magnesium Sulfate ; Magnesium* ; Potassium* ; Rabbits* ; Tachycardia

No abstract available.
Humans

The paratertiary butylphenol formaldehyde resin (PTBP-FR) is commonly used as a shoe adhesives because it sticks rapidly, is durable and pliable, and maintains good bond strength at raised temperature. We report two cases of allergic contact dermatitis due to PTBP-FR-containing shoes. Two women visited our department because of the skin rash on their .
Adhesives ; Dermatitis, Allergic Contact* ; Exanthema ; Female ; Formaldehyde* ; Humans ; Shoes*

No abstract available.
Giant Cells ; Granuloma, Giant Cell ; Mandible

The common sites of solitary bone cyst(SBC) are humerus, femur and less common sites are tibia, calcaneus, ilium, fibula, radius and ulna. Ischium rib, scapula, spine, clavicle and patella are rare sites of solitary bone cyst. As mentioned above, SBC of patella is very rare and on view of literatures we could find only one reported case which was treated by patellectomy. We also experienced one case of SBC located at patella, so we report this case with review of literatures.
Bone Cysts ; Calcaneus ; Clavicle ; Femur ; Fibula ; Humerus ; Ilium ; Ischium ; Patella ; Radius ; Ribs ; Scapula ; Spine ; Tibia ; Ulna

A 69-year-old-male patient was admitted because of left upper quadrant (LUQ) abdominal pain He had hard palpable mass (abaut 15x l0cm) in LUQ abdomen and mild elevated serum alkaline phosphatase (349 IU/L) and amylase (216 U/L) levels at the admission time. Abdominal CT scan revealed huge, well-marginated cystic mass in enlarged spleen with increased densities in dependent portion of cystic mass, about 8x13cm in size. Another small well-capsulated. cystic mass in anterior aspect of spleen was also seen. After ERCP, urgent surgical intervention was done. Final diagnosis was chronic pancreatitis with large intrasplenic (l2x9.5 cm) and retroperitoneal pseudocysts. So we are reporting above case with pertinent review of literatures.
Abdomen ; Abdominal Pain ; Alkaline Phosphatase ; Amylases ; Cholangiopancreatography, Endoscopic Retrograde ; Diagnosis ; Humans ; Pancreatitis, Chronic* ; Spleen ; Splenomegaly ; Tomography, X-Ray Computed

Sixteen patients with prostatodynia underwent clinical studies including urodynamic study, MMPI, and endoscopy. As a control group, another 19 patients with nonbacterial prostatitis and 16 normal man of 20-40 years of age also underwent urodynamic study. The most characteristic urodynamic findings in patients with prostatodynia was a significant increase in maximum urethral closing pressure as compared to control group (mean, 140.9 : 92.1 : 84.1 cmH20). In prostatodynia group, peak urinary flow rate was also significantly decreased as compared to the control group (mean, 12.0: 17.8 : 23.9cc / sec). 11 of 16 patients with prostatodynia was found to have functional outlet obstruction, probably at sympathetically innervated urethral sphincter. And they were treated with minipress and diazepam, of whom 7 showed significant improvement both symptomatically and urodynamically. On MMPI 7patients with prostatodynia showed significant underlying psychiatric disorders, and were treated by psychiatric treatment, of whom 4 showed significant clinical improvement. 2 patients with prostatodynia showed vermontanal pseudopolyp suggestive of prostatitis, were treated with long term TMF-SMX administration, and showed significant improvement. It is suggested that prostatodynia may develop from urethral sphincter overactivity and underlying psychiatric disorders, and that at least some cases with prostatodynia are in fact prostatitis. Uroflowmetry, urethral pressure profile, MMPI study and repeated EPS study may be of help in deciding the treatment plan of prostatodynia.
Diazepam ; Endoscopy ; Humans ; MMPI ; Prazosin ; Prostatitis ; Urethra ; Urodynamics*

A 38-year-old female patient presented dystrophic nail changes on her all finger and toe nails for 10 years. On examination, nails were uniformly affected with longitudinal ridging, loss of normal luster and brownish discoloration. This patient has not had any inflammatory skin diseases or systernic illness for the past 10 years. Biopsy examination from the dystrophic nail showed non-specific eczematous changes. The clinical and histologic features of this yatient was considered as the consistent findings with the ty enty-nail dystrophy, occured on the idiopathic base, coined by previous authors.
Adult ; Biopsy ; Female ; Fingers ; Humans ; Numismatics ; Skin Diseases ; Toes

Macrostomia is a relatively rare malformation. There have been many surgical methods for the correction of macrostomia. The old method, a simple straight line closure , did not include reconstruction of the orbicularis oris muscle. Postoperatively, a depressed scar and severe contraction on the cheek were found, especially with animation. As a result, many authors have known that reconstruction of the orbicularis oris muscle was very important to avoid a depressed scar for the correction of macrostomia. The tendency toward lateral displacement of the reconstructed commissure has been attributed to linear scar contraction, and Z-plasty is advocated to prevent this deformity. However, we found that the Z-plasty scar may be conspicuous when the patient smiles. So we performed reconstruction of the orbicularis oris muscle to avoid a depressed scar, and straight line closure to avoid a conspicuous scar. In order to prevent linear scar contracture due to straight line closure, we overcorrected the new commissure. We treated 6 cases of macrostomia form May 1, 1996 to April 30, 1999 using straight line closure and reconstruction of the orbicularis oris muscle. Periods of follow-up were from 12 months to 35 months, with an average of 20,2 months. Every patient was analyzed clinically by ordinary scale method and anthropometrically by the ratio of abnormal distances to normal distances between cheilion and crista philtri. In 3 clinical assessments : symmetry of the commissure was excellent: degree of the scar at rest was good: and degree of depression with animation was excellent. The anthropometrical ratio was 1:1.05. Despite the fact that the linear scars were perpendicular to the minimal skin tension lines, the scars were inconspicuous. The muscle repair provided reconstruction to the modiolus and gave a natural appearance to the commissure, however it did not seem to provide sufficient bulkiness around the commissure. The straight line skin closure and repair of the orbicularis oris muscle provide effective functional and aesthetic reconstruction.
Cheek ; Cicatrix ; Congenital Abnormalities ; Contracture ; Depression ; Follow-Up Studies ; Humans ; Macrostomia* ; Skin

BACKGROUND: Intravenous patient-controlled analgesia (IV-PCA) has been widely used for pain relief after cesarean delivery under epidural anesthesia. However, IV-PCA alone has a limited effect on early postoperative pain relief. Epidural morphine injected intraoperatively could alleviate the early postcesarean pain. We evaluated the effects and side effects of intraoperative epidural morphine on postoperative IV-PCA. METHODS: Forty patients scheduled for cesarean section under epidural anesthesia were randomly assigned to one of two groups. The patients in the intravenous group (IV group, n = 20) received intravenous morphine 3 5 mg after the operation in the recovery room when patients complain of pain, and the patients in the epidural group (EPI group, n = 20) received intraoperative epidural morphine 3 mg after fetus delivery. After that, both groups received morphine IV-PCA (no basal infusion, bolus 1.0 mg, lock-out time 6 min). Analgesic efficacy, degree of patient satisfaction, drug consumption and side effects were compared at 4 and 24 hours after surgery. RESULTS: The EPI group had significantly lower VAS for pain at 4h after surgery on movement and resting than the IV group, whereas no significant difference was observed at 24h after surgery. The cumulative morphine consumptions at 4h and 24h after surgery were more in the IV group (each, P < 0.001). Fewer patients in the EPI group had drowsiness at 24h after surgery, but there were no significant differences in other side effects and degree of satisfaction between the two groups. CONCLUSIONS: We conclude that intraoperative epidural morphine was effective with less side effects for postoperative IV-PCA in the cesarean patients under epidural anesthesia.
Analgesia, Patient-Controlled* ; Anesthesia, Epidural ; Cesarean Section ; Female ; Fetus ; Humans ; Morphine* ; Pain, Postoperative ; Patient Satisfaction ; Pregnancy ; Recovery Room ; Sleep Stages