IgA nephropathy was found in a 21-year-old woman with psoriasis vulgaris. She was first diagnosed as psoriasis vulgaris at 12 years age and had exhibited microscopic hematuria and proteinuria since 20 years of age. The histological findings of the renal biopsy showed mesangial proliferative glomerulonephritis and sclerosis. Mensangial deposits of IgA were observed by immunofluorescence. Therefore, we diagnosed this case as IgA nephropathy. Immune abnormalities have been reported in both diseases. The pathogenesis of psoriasis vulgaris and IgA nephropathy may be related through an immune mechanism. The overlapping or coexistence of these conditions has rarely been reported. Thus we described with IgA nephropathy associated with psoriasis vulgaris, psoriatic arthritis, and review the literatures.
Arthritis, Psoriatic* ; Biopsy ; Female ; Fluorescent Antibody Technique ; Glomerulonephritis ; Glomerulonephritis, IGA* ; Hematuria ; Humans ; Immunoglobulin A* ; Proteinuria ; Psoriasis* ; Sclerosis ; Young Adult