1.The Effect of Clonidine Added to Bupivacaine on Intercostal Nerve Block for Postoperative Pain Control.
Woo Jong YOU ; Hyun Soo JANG ; Han Mok YOU ; Sang Ha LEE
Korean Journal of Anesthesiology 2000;39(2):196-201
BACKGROUND: The addition of clonidine to local anesthetics for regional block has been shown to increase the duration of anesthesia and analgesia. This study was designed to determine whether the addition of clonidine to bupivacaine would produce an extension of the analgesic effect after intercostal nerve block (ICNB). METHODS: After informed consent, 30 ASA 1 or 2 patients undergoing appendectomy under general anesthesia were randomly divided into two groups. Before induction of anesthesia, ICNB using a posterior approach was performed with 15 ml of 0.25% bupivacaine plus epinephrine 1:200,000 with (Group BEC; n = 15) or without (Group BE; n = 15) clonidine 75 microgram. Analgesia was assessed by cold testing at 1/min intervals until cold sensation decreased. The duration of analgesia (time between injection and onset of pain) was recorded. We also recorded the visual analogue scale (VAS) of pain, the number of supplemental analgesics, heart rate and blood pressure, and side effects over 24 hours postoperatively. RESULTS: The onset time, duration of analgesia, number of analgesics, and heart rate and blood pressure were comparable in both groups. VAS scores were significantly lower in Group BEC than in Group BE at 12, 16, and 20 hours postoperatively. CONCLUSIONS: The addition of clonidine to bupivacaine with epinephrine may be a useful adjunct and can prolong the duration of analgesia after ICNB without significant side effects.
Analgesia
;
Analgesics
;
Anesthesia
;
Anesthesia and Analgesia
;
Anesthesia, General
;
Anesthetics, Local
;
Appendectomy
;
Blood Pressure
;
Bupivacaine*
;
Clonidine*
;
Epinephrine
;
Heart Rate
;
Humans
;
Informed Consent
;
Intercostal Nerves*
;
Pain, Postoperative*
;
Sensation
2.A case of congenital giant pigmented nevus.
Seung Wan LEE ; Wu Ha YOU ; Chang Bin IM ; Chang Woo LEE ; Chan Kum PARK
Journal of the Korean Pediatric Society 1992;35(5):723-728
No abstract available.
Nevus, Pigmented*
4.A study of calcium and inorganic phosphorus levels in maternal and cord blood.
Woo Ha YOU ; Seung Wan LEE ; Jong Lin RHI ; Hyun Joo JEONG ; Yong Joon SHIN ; Chung Hak PARK
Journal of the Korean Pediatric Society 1992;35(4):492-498
No abstract available.
Calcium*
;
Fetal Blood*
;
Phosphorus*
6.Clinical study on cesarean hysterectomy.
Sung Hun HA ; You Dong CHO ; Man Chul PARK ; Joo Hyun NAM ; Yong Woo LEE ; Won Sop OH ; Jwa Koo CHUNG
Korean Journal of Obstetrics and Gynecology 1993;36(7):1822-1827
No abstract available.
Hysterectomy*
7.Acute renal failure due to bilateral pyelonephritis.
Byoung Ha KIM ; Woo Taek TAK ; You Sik CHOI ; Jong Tae CHO ; Sung Chul YOON
Korean Journal of Medicine 2002;62(3):297-301
Acute renal failure is a rare complication of acute pyelonephritis. Therefore, acute pyelonephritis is not usually considered in the differential diagnosis of acute renal failure. However, it is important to consider this entity because of potential for recovery of renal function if appropriate early antibiotics are instituted. We report a case of biopsy proven acute pyelonephritis which was manifested as acute renal failure. A 38 year old women was admitted to this hospital owing to abdominal distension and generalized edema. On admission she was started on hemodialysis because of severe hyperkalemia and marked uremic sypmtoms. She had pyuria and hematuria, but no organism was isolated at urine. We initially don't know the cause of renal failure. She was improved with antimicrobial therapy and hemodialysis. A kidney biopsy was performed on the 26th hospital day because of persistent proteinuria. Microscopic examination revealed focal tubular atrophy, necrosis or loss with heavy infilteration of leukocytes and histocytes in interstitium. Atrophic tubules contain pus casts. The patient was treated with ciprofloxacin for 4 weeks. At about 2 month follow up, proteinuria completely disappeared and serum creatinine level decreased to 1.0 mg/dL.
Acute Kidney Injury*
;
Adult
;
Anti-Bacterial Agents
;
Atrophy
;
Biopsy
;
Ciprofloxacin
;
Creatinine
;
Diagnosis, Differential
;
Edema
;
Female
;
Follow-Up Studies
;
Hematuria
;
Humans
;
Hyperkalemia
;
Kidney
;
Leukocytes
;
Necrosis
;
Proteinuria
;
Pyelonephritis*
;
Pyuria
;
Renal Dialysis
;
Renal Insufficiency
;
Suppuration
8.Maternal and neonatal outcomes after multiple administration of dexamethasone to patients with preterm premature rupture of membranes.
Tae Joong KIM ; Woo Youg KIM ; Jin Kyung YOU ; Jong Dae WHANG ; Soon Ha YANG ; Je Ho LEE ; Cheong Rae ROH
Korean Journal of Obstetrics and Gynecology 2000;43(9):1646-1651
No abstract available.
Dexamethasone*
;
Humans
;
Membranes*
;
Rupture*
9.Multiplex Ligation Dependent Probe Amplification (MLPA) Assay on Joseon Mummified Samples from Archaeological Sites of South Korea.
You Soo KIM ; Chang Seok OH ; Jong Ha HONG ; Moon Woo SEONG ; Dong Hoon SHIN
Korean Journal of Physical Anthropology 2015;28(3):137-143
Multiplex Ligation dependent Probe Amplification (MLPA) to detect large deletions or duplications has been widely used as a diagnostic tool for various disease clinically. As this method requires only a small amount of template DNA and is very simple and high throughput, it has numerous advantages for the analysis of the human specimen obtained from archaeological sites. In this study we therefore tried to perform MLPA analysis for detecting any of duplications or deletions in mummy samples (n=4) from medieval Joseon tombs of Korea. Of them, we could not get any authentic data from 3 samples by MLPA method while only one case (HD2) showed the possible presence of duplications or deletions during her lifetime. Although the current report reveal that MLPA is a promising tool for anthropological study in South Korea, more studies are still needed to make up for the validity problem of commercial MLPA kit used in this study.
DNA
;
Humans
;
Korea*
;
Multiplex Polymerase Chain Reaction*
;
Mummies
10.Death due to Aspergillus Tracheobronchitis: An Autopsy Case
Tack Kune YOU ; Byung Ha CHOI ; Bong Woo LEE ; Young Shik CHOI
Korean Journal of Legal Medicine 2018;42(4):164-167
Aspergillus infection is the most common cause of death due to fungi in immunocompromised hosts. Aspergillus tracheobronchitis is an uncommon but severe form of invasive pulmonary aspergillosis, which is limited entirely or mainly to the tracheobronchial tree and can often be life-threatening. We report a case of a 54-year-old man who died from Aspergillus tracheobronchitis without an underlying disease. Autopsy revealed an extensive yellowish plaque adhering to the trachea and bronchial wall. The microscopic examination of the trachea and bronchus revealed septate branching hyphae of Aspergillus.
Aspergillus
;
Autopsy
;
Bronchi
;
Bronchitis
;
Cause of Death
;
Fungi
;
Humans
;
Hyphae
;
Immunocompromised Host
;
Invasive Pulmonary Aspergillosis
;
Middle Aged
;
Trachea
;
Tracheitis
;
Trees