1.A Case of Acantholytic Dyskeratotic Epidermal Nevus.
Gun Yoen NA ; Yong Hyun KIM ; Jeong Woo LEE
Annals of Dermatology 1997;9(1):8-10
We report a case of acantholytic dyskeratotic epidermal nevus in a 28-year-old female. The patient showed unilateral, asymptomatic, grouped, 2 mm sized, brownish, follicular ant non-follicular, keratotic papules disposed along Blaschko´s lines on the right side of th back, flank and abdomen. She had had this condition for 4 years. The biopsy specimen obtaine, from the abdomen showed hyperkeratosis, parakeratosis, acanthosis, acantholytic suprabasal clefts, corps ronds, and grains. Although cryotherapy with liquid nitrogen was per formed on half of the lesions, the whole skin lesions healed with focal hypertrophic scars 4 weeks later. There was no recurrence after a 12 months follow-up period. To our knowledge this is the first reported case of acantholytic dyskeratotic epidermal nevus in Korean dermatologi, literature.
Abdomen
;
Adult
;
Ants
;
Biopsy
;
Cicatrix, Hypertrophic
;
Cryotherapy
;
Darier Disease*
;
Female
;
Follow-Up Studies
;
Humans
;
Nitrogen
;
Parakeratosis
;
Recurrence
;
Skin
2.The Reconstruction with Extracorporeal Irradiated Autograft for Osteosarcoma of Extremities.
Jae Do KIM ; Gun Woo LEE ; So Hak CHUNG
The Journal of the Korean Bone and Joint Tumor Society 2010;16(1):1-7
PURPOSE: With advances in various treatment modalities, limb salvage surgery has been commonly used in osteosarcoma of extremities. An alternative method for skeletal reconstruction is reimplantation of the tumor bearing bone following extracorporeal irradiation (ECI). We report the long-term results of ECI autograft in aspect of the oncological and functional outcomes, and complications. MATERIALS AND METHODS: We retrospectively reviewed 31 osteosarcoma patients who underwent reconstruction with ECI between July 1995 and January 2006. There were 24 males and 7 females with a mean age of 24 (7-74 years) and a mean follow-up of 117 months (17-177 months). Twenty-five cases were reconstructed with ECI autograft, 6 cases with ECI autograft-prosthesis composite. The pathologic subtypes were conventional in 29 cases, periosteal in 1 case, and parosteal in 1 case. The most common location of tumor was distal femur (15 cases) followed by humerus (3), proximal fibula (3) and proximal tibia (3). Musculoskeletal Tumor Society (MSTS) score was used for functional evaluation. The overall survival rate, local recurrence, complications were analyzed. RESULTS: The overall survival rate was 80.6% and the disease-free survival rate was 64.5%. Five patients died of distant metastasis. One patient required above-knee amputation due to local recurrence. All of them, twenty-three complications occurred, which included nonunion in 7 cases, deep infection in 5 cases, joint instability in 4 cases, metal failure in 2 cases, Limb-length discrepancy (LLD) in 2 cases, periprosthetic fracture in 1 case, epiphyseal collapse in 1, local recurrence in 1 case. The mean MSTS functional score was 62.5%. CONCLUSION: Extracorporeal irradiated autograft can be achieved relatively good result in aspect of oncological and functional aspect, but is needed to be additional research about occurring many complications. The reconstruction with ECI after intercalary or fragmentary resection is effective reconstruction in aspect of oncological and functional result, complications.
Amputation
;
Disease-Free Survival
;
Extremities
;
Female
;
Femur
;
Fibula
;
Follow-Up Studies
;
Humans
;
Humerus
;
Joint Instability
;
Limb Salvage
;
Male
;
Neoplasm Metastasis
;
Osteosarcoma
;
Periprosthetic Fractures
;
Recurrence
;
Replantation
;
Retrospective Studies
;
Survival Rate
;
Tibia
;
Ursidae
3.A case of dyskeratosis congenita.
Ji Whan HAN ; Jong Woo BAE ; Woo Gun CHOI ; Hack Ki KIM ; Kyong Su LEE
Korean Journal of Hematology 1991;26(2):425-428
No abstract available.
Dyskeratosis Congenita*
5.Current Management of Talar Fractures
Journal of the Korean Fracture Society 2022;35(1):31-37
Talar fracture management is one of the most challenging tasks for orthopedic surgeons. High complication rates and functional impairments after talar fractures have been well documented, and thus, surgical strategies capable of perfect anatomic reduction and stable fixation are important. The current review was undertaken to provide recommendations regarding updated surgical strategies that include surgical timing, approach, fixation methods, and the prevention and treatment of possible complications.
6.A clinical study of childhood acute mixed lineage leukemia.
Kwang Kook MIN ; Young Woo KIM ; Woo Gun CHOI ; Hack Ki KIM ; Ik Jun LEE ; Kyong Su LEE
Korean Journal of Hematology 1993;28(2):365-371
No abstract available.
Leukemia*
7.Two cases of hybrid leukemia.
Sung Dong CHOI ; Dae Chul JUNG ; Woo Gun CHOI ; Hack Ki KIM ; Kyong Su LEE
Journal of the Korean Pediatric Society 1991;34(1):130-136
No abstract available.
Leukemia*
8.Is 99mTc-MDP Mammoscintigraphy Useful in Patients with Breast Mass Lesions ?.
Seok Gun PARK ; Yeon Hee LEE ; Jin Woo RHYU ; Sun Mee YOU
Korean Journal of Nuclear Medicine 1998;32(2):151-160
PURPOSE: Piccolo et al. advocated the usefulness of Tc-99m-MDP breast scan in differential diagnosis of breast mass with high accuracy. But there are little or no follow-up studies about it as we know. We studied Tc-99m-MDP uptake pattern and lesions/background ratio in patients complaining palpable breast lesions to evaluate the clinical usefulness of Tc-99m-MDP scan. MATERIALS AND METHODS: Total 34 patients were studied with physical examination, mammogram and Tc-99m-MDP scan prospectively. Anteroposterior and both lateral view of breast were obtained 5 minutes after iv injection of 740 MBq Tc-99m-MDP. Breast uptake pattern of Tc-99m-MDP was analyzed by a grade system: 0=no uptake, grade 1=bilateral diffuse uptake, grade 2=asymmetric faint uptake, grade 3=focal hot uptake. 20 cases were pathologically confirmed by excision biopsy or aspiration biopsy. 14 cases were normal in physical examination and mammo-grain. RESULTS: Pathologic results showed 7 carcinomas, 6 benign solid tumors, and 7 fibrocystic changes. Grade 3 pattern of Tc-99m-MDP uptake was noted in 4/7 carcinomas, 3/6 benign solid tumors, and 1/7 fibrocystic changes. Grade 2 pattern was 2/7, 0/7, 3/7 respectively. The average L/B ratio was 1.66 in carcinomas, 1.68 in benign solid masses, 1.20 in fibrocystic diseases, 1.05 in normal patients. L/B ratio was higher in carcinoma and benign mass groups than in fibrocystic change and normal control groups(p=0.005). But there was no statistical difference between L/B ratio of malignant mass group and benign mass group. CONCLUSION: Tc-99m-MDP scan is not suitable to routine clinical use for breast mass diagnosis. It might be used in limited conditions when whole body bone scan is planned.
Biopsy
;
Biopsy, Needle
;
Breast Neoplasms
;
Breast*
;
Diagnosis
;
Diagnosis, Differential
;
Follow-Up Studies
;
Humans
;
Mammography
;
Physical Examination
;
Prospective Studies
;
Technetium Tc 99m Medronate*
9.The Effect of Topical Anesthesia on the Oculocardiac Reflex.
Journal of the Korean Ophthalmological Society 1986;27(5):829-832
Under the general anesthesia the effect of topical anesthesia on the incidence of oculocardiac reflex was investigated by preoperative instillation of 0.5% tetracaine into the 48 eyes during horizontal strabismus muscle surgery. In all cases, recession was done first. The results were as followings: 1. The incidences of oculocardiac reflex in treated and control group were 33% and 71% respectively and the difference was statistically significant(p<0.025). 2. The reduction in the incidence of oculocardiac reflex was noted both in recession and resection. But there was no statistically significant difference between treated group and control group in resection. 3. The incidence of oculocardiac reflex was not related with age, sex, type of strabismus, kind of muscles and type of surgery.
Anesthesia*
;
Anesthesia, General
;
Incidence
;
Muscles
;
Reflex, Oculocardiac*
;
Strabismus
;
Tetracaine
10.The Significance of Sentinel Node Biopsy in Malignant Melanoma and Squamous Cell Carcinoma of Lower Extremities.
Jae Do KIM ; Gun Woo LEE ; Young Ho KWON ; So Hak CHUNG
The Journal of the Korean Bone and Joint Tumor Society 2010;16(2):69-73
PURPOSE: Sentinel lymph node (SLNB) is the first confronted lymph node from primary lesion of tumor through lymphatic drainage, which is important for determining early metastasis and setting guidelines for treatment. We reported significant of sentinel lymph node biopsy in malignant melanoma (MM) and squamous cell carcinoma (SCC) of lower extremities. MATERIALS AND METHODS: Twenty-five cases of surgically treatment and being possible for follow up more than 1 year among the patients who were diagnosed as MM and SCC in this institution from Sep. 2005 to Jan. 2009, and 10 cases of them were performed SLNB. Average age was 64 years old, and 15 cases of male and 10 cases of female were in this group. RESULTS: 3 years overall survival rate was 100% and 3 years disease-free survival rate was 76%. Metastasis occurred in total 6 patients, 4 cases of inguinal lymph nodes, 1 case of soft tissue around knee, 1 case of left achilles tendon. In 15 cases of not performing SLNB, overall survival rate was 93.3% and disease-free survival rate was 73.3%. In 10 cases of performing SLNB, overall survival rate was 100% and disease-free survival rate was 90%. And only 1 case showed positive finding in the biopsy, and none of the 10 cases showed metastasis in follow-up. CONCLUSION: SLNB leads simpler and less complications compared to prior elective lymph node dissection, and shows high degree of accuracy. Throughout the SLNB, setting guidelines for treatment by accurate staging is thought to be helpful for increasing the survival rate in the patient with MM and SCC.
Achilles Tendon
;
Biopsy
;
Carcinoma, Squamous Cell
;
Disease-Free Survival
;
Drainage
;
Female
;
Follow-Up Studies
;
Humans
;
Knee
;
Lower Extremity
;
Lymph Node Excision
;
Lymph Nodes
;
Male
;
Melanoma
;
Neoplasm Metastasis
;
Nitriles
;
Pyrethrins
;
Sentinel Lymph Node Biopsy
;
Survival Rate