The gross tissue specimens are a valuable aid to the teaching of pathology and anatomy. However, traditional methods for storage and handling of them are discouragingly difficult and, recently, minimal surgical resections as well as preoperative interventions make it more difficult to have instructive gross specimens. Plastination is a process of tissue preservation by impregnation with silicone polymers or epoxy resins. The process in our study involves dehydration by cryosubstitution in aceton, defatting, forced impregnation of silicon polymer in a vacuum, curing and finishing. We submitted 40 surgically resected specimens to plastination. The resulting specimens are odorless, relatively dry, durable, life-like, non-hazardous, maintenance-free, and do not deteriorate with time. Plastinated specimens are a useful adjunct to the teaching of pathology, particularly suited for use in small groups, and appropriate method of tissue preservation. They are much preferred to wet preparation and conventional pots by both students and teachers owing to their accessibility, superior illustrative powers, and comparative ease of interpretation.
Dehydration ; Epoxy Resins ; Humans ; Pathology* ; Polymers ; Silicones ; Tissue Preservation ; Vacuum

There have been many reports about surgical treatments of flexible flatfoot in children and acquired adult flatfoot deformity due to posterior tibial tendon dysfunction common in the 5th and 6th decades. However there has been a controversy for surgical treatment guideline for painful idiopathic flexible flatfoot deformities in young adults. Therefore, we present a 27-year-old female with severe painful idiopathic flexible flatfoot who was treated with medial sliding calcaneal osteotomy and subtalar arthroereisis using Kalix(R) (Newdeal SA, Vienne, France) endoprosthesis and had good clinical outcome with high patient satisfaction at 10 months follow-up postoperatively.
Adult* ; Child ; Congenital Abnormalities ; Female ; Flatfoot* ; Follow-Up Studies ; Humans ; Osteotomy* ; Patient Satisfaction ; Posterior Tibial Tendon Dysfunction ; Young Adult

PURPOSE: To assess the clinical difference between cubital tunnel syndrome with anconeus epitrochlearis (AE) and idiopathic cubital tunnel syndrome without known other causes. METHODS: This cross-sectional study included the 326 patients who were subjected to surgery because of cubital tunnel syndrome from 2008 to 2014. After exclusion of patients with other known causes of cubital tunnel syndrome, a total of 107 patients were divided into two groups; patients with and without AE. The clinical differences between two groups were analyzed retrospectively; age, sex, presence of intrinsic muscle atrophy, interval from symptom development to surgery, pinch power, the disabilities of the arm, shoulder and hand score and the nerve conduction velocity (NCV). RESULTS: Thirty four (10.4%) patients, being subjected to surgery had the AE. Among 107 patients who had no other known causes, 26 patients had AE. 19 out of 26 patients with AE was male. Average age of patients with AE was significantly younger. The interval from symptom development to surgery in AE patients was significantly shorter. Motor NCV of ulnar nerve at above elbow joint in comparison with that at below elbow joint in AE patient was more significantly decreased (14.3 m/sec vs. 8.3 m/sec). CONCLUSION: The AE in cubital tunnel syndrome is no more rare structure. In younger male patients with rapidly progressive worsening cubital tunnel symptoms, and if there is significant decrease of ulnar motor nerve velocity at above elbow in comparison with at below elbow, the AE should be considered as cause of ulnar neuropathy.
Arm ; Cross-Sectional Studies ; Cubital Tunnel Syndrome* ; Elbow ; Elbow Joint ; Hand ; Humans ; Male ; Muscular Atrophy ; Neural Conduction ; Retrospective Studies ; Shoulder ; Ulnar Nerve ; Ulnar Neuropathies

Total of 53 patients of unresectable and recurrent rectal cancer treated with neutron beam during the period from Oct. 1987 to Apr. 1992 were analyzed. Dose fractionation for the neutron only group was 1.5 Gy per fraction, 3 fraction per week, 21 Gy/41/2 wks for 42 patients out of 53(76%). Neutron only but modified fractionation schedule (10% more or less of total dose) was applied for 9 patients, and mixed team (neutron boost) was for 4 patients. Complete tumor response was obtained in 40 patients(76% response rate). Local control rate was 28 out of 53(53%). Statistically significant better prognostic factors for local control were age below 49 years old (15/22, 68%) than above 50 years old (13/31, 42%), male (20/32, 63%) than female(8/21, 38%), tumor size less than 5 cm and non-metastatic(16/24, 67%) than size more than 5 cm or metastatic(12/29, 4l%). Major complication had developed in 7 patients (13%). Two year overall survival rate by Kaplan-Meier method was 30%, but it was rised to, 47% when the tumor was less than 5cm non-metastatic.
Appointments and Schedules ; Dose Fractionation ; Humans ; Male ; Middle Aged ; Neutrons* ; Rectal Neoplasms* ; Survival Rate

No abstract available.
Hypoglycemia ; Paresis*

The aim of this study was to evaluate the effect of mouthrinse products containing deep sea water. We used original deep sea water (DSW) and processed deep sea water desalinated by reverse osmosis at one time (DDW-1), by reverse osmosis at two times (DDW-2) and concentrated by reverse osmosis (CDW). We made 2 kinds of mouthrinse products containing CDW and other agents for smell and taste and one product without deep sea water. The negative control was distilled water. In vivo study, the dental plaque index scores and the gingival index scores were reduced after 4 weeks mouthrinsing three times daily with 4 kinds of deep sea water and 3 kinds of mouthrinse products(p<0.05). The pH of dental plaque in 1 minute after mouthrinsing was not higher than 5.5 in all solutions, but the pH in 20 minutes after mouthrinsing was higher than 5.7 in DSW, CDW and 3 kinds of products which had higher mineral contents. In vitro study, the mouthrinse solutions containing the higher mineral contents were also the more effective in reduction of methyl mercaptan which is one of the causes of halitosis. The 2 kinds of products containing deep sea water killed Streptococcus mutans (ATCC 25175) in culture plates in one minute. These results indicate the usability of deep sea water in mouthrinses for oral hygiene management.
Dental Plaque ; Dental Plaque Index ; Halitosis ; Hydrogen-Ion Concentration ; Oral Hygiene ; Osmosis ; Periodontal Index ; Seawater* ; Smell ; Streptococcus mutans ; Water

Myoepithelial carcinoma is a very rare malignant tumor accounting for less than one percent of the salivary gland neoplasms. This uncommom tumor, showing almost exclusively tumor cells with myoepithelial differentiation, is most commonly diagnosed in the parotid gland and in the minor silivary glands of the palate. We report a 77-year-old woman with myoepithelial carcinoma originating from maxillary sinus, one of the most unusual locations. The patient presented with progressive nasal obstruction and signs of a space-occupying lesion in the left maxillary sinus. A frozen biopsy identified a malignant tumor and a radical maxillectomy was performed. Histology confirmed the presence of a malignant myoepithelial carcinoma. Patient was followed up for one year without any recurrence or distant metastasis.
Accounting ; Aged ; Biopsy ; Female ; Humans ; Maxillary Sinus ; Myoepithelioma ; Nasal Obstruction ; Neoplasm Metastasis ; Palate ; Parotid Gland ; Recurrence ; Salivary Gland Neoplasms

We tried to establish the theoretical basis of clinical use of combined modality of hyperthermia and radiation therapy. For this purpose, we made an in vitro experiment in order to get the synergistic and/or additive effects on the cell killing of hyperthermia combined with radiation therapy by using the microwave-hyperthermia machine already installed at our department. In our experiment, we use two human cell lines: MKN-45(adenocarcinoma of stomach) and K-562(leukemia cell lines). In cases of combined treatments of hyperthermia and gamma-irradiation, the therapeutic effect was the highest in the simultaneous trial. Hyperthermia after gamma irradiation showed slightly higher therapeutic effect than that before irradiation without significant difference, but its effect was the same in the interval of 6 hours between hyperthermia and irradiation. The higher temperature and the longer treatment time were applied, the higher therapeutic effects were observed. We could observe the thermoresistance by time elapse at 43 degree C. When hyperthermia was done for 30 minutes at the same temperature, thermal enhancement ratio(TER) at D0.01(dose required surviving fraction of 0.01) were 2.5+/-0.08, 3.75+/-0.18, and 5.0+/-0.15 at 43 degree C, 44 degree C, and 45 degree C respectively in K-562 leukemia cell lines. Our experimental data showed that more cell killing effect can be obtained in the leukemia cell lines, although they usually are known to be radiosensitive, when treated with combined hyperthermia and radiation therapy. Furthermore, our data show that leukemia cell lines May have various intrinsic radiosensitivity, especially in vitro experiments. The magnitude of cell killing effect, however, will be less than that of MKN-45.
Cell Line* ; Fever* ; Homicide ; Humans* ; Leukemia ; Radiation Tolerance

PURPOSE: Eventhough cadaveric renal grafts are increasing, kidneys from living donors remain as the major mode of renal transplantations and there is a need to establish theoretical bases for securing the safety of the donors. Follow-up of donors was done for a year using several indices of renal function to evaluate the function of the remaining kidneys after donor nephrectomies. MATERIALS AND METHODS: Two hundred and sixty one living donors were included in this study. Blood urea nitrogen(BUN), serum creatinine, 24 hour creatinine clearance, 24 hour urine protein, and blood pressure were checked preoperatively. The same indices were checked at one, six, and twelve months after the operation. These indices were compared with those before the operation. RESULTS: Although some increase was observed in serum BUN, creatinine, and 24hr urine protein, and decrease in creatinine clearance after donor nephrectomies, all were within normal limits, which did not show clinically significant differences. All indices did not deviate from the normal limits through-out one year. CONCLUSIONS: Renal indices varied within normal limits and donor nephrectomies seemed to cause no significant harmful effect on the donors. Prospective and long term follow-up of the donors after donor nephrectomies are needed to ensure a high quality life of living donors.
Blood Pressure ; Cadaver ; Creatinine ; Follow-Up Studies* ; Humans ; Kidney ; Kidney Transplantation ; Living Donors ; Nephrectomy* ; Tissue Donors* ; Transplants ; Urea

Kawasaki disease is an acute systemic vasculitis of unknown origin. Coronary aneurysm or ectasia is one of the most serious complications of Kawasaki disease. The major complication of Kawasaki coronary disease is myocardial infarction caused by thrombus formation inside the aneurysm or by organic obstructive lesion following the regression of aneurysm. Percutaneous balloon angioplasty, rotational ablation, directional coronary artherectomy, stent insertion and coronary artery bypass graft can be used to treat coronary artery stenosis or occlusion. We describe a 6-year old boy who had an episode of Kawasaki disease with giant coronary artery aneurysm diagnosed at the age of 3 years. Surveillance echocardiogram showed giant coronary aneurysm with stenosis and large mural thrombus in the proximal portion of left main coronary artery. So we inserted two polytetrafluoroethylene(PTFE) covered graft stent without complication.
Aneurysm ; Angioplasty, Balloon ; Child ; Constriction, Pathologic* ; Coronary Aneurysm* ; Coronary Artery Bypass ; Coronary Disease ; Coronary Stenosis ; Coronary Vessels ; Dilatation, Pathologic ; Humans ; Male ; Mucocutaneous Lymph Node Syndrome* ; Myocardial Infarction ; Stents* ; Systemic Vasculitis ; Thrombosis* ; Transplants*