Lipodystrophia centrifugalis ahdominalis infantilis(LCAI), an atypical form of progressive lipodystrophy, is a diseaee named by Imamura et al in 1971, and reported a few cases in japan. We report a case who has diagnosed as LCAI. The patient ia 5 and half year old boy. He had 2cm by 7cm sized, linear depressed leaion with surrounding erythema on the right inguinal region which was noticed 5 months prior to first diagnosis. There was no family history, no physical abnormality except skin lesion. Cornplete blood cell count, urinalysis, stool examination, liver function test and chest X-ray were within normal limit. Biopsy specimens from the depressed lesion and surrounding erythematous area revealed slight atrophy of the epidermis, a mild lymphocyte infiltration around the vesaels and eccrine glands in the upper part of derrnis, markedly decreased amount of subcutaneous adipoae tissue with mild lymph- ocyte infiltration in depressed area and marked lymphocyte infiltration, intermingled with histiocyte in surrounding erythematous area, but normal amount of adipase tissue.
Atrophy ; Biopsy ; Blood Cell Count ; Diagnosis ; Eccrine Glands ; Epidermis ; Erythema ; Histiocytes ; Humans ; Japan ; Lipodystrophy ; Liver Function Tests ; Lymphocytes ; Male ; Skin ; Thorax ; Urinalysis

We describe herein a case of tick bite ocurring to a 23-year-old man who has a characteristic lesion clinically and histopathologically. The tick(Ixodes sp.) was still attached to the brownish and erythematous, indurated skin of the scrotum. The engorged tick which was carefully removed from the skin with a scalpel was 8.7mm in length and 5. 5 mm in width. Histopathologically, characteristic amorphous eosinophilic materigl is deposited around a round space where the hypostorne of the tick was inserted. Heavy inflammatory cell infiltratton in the mid and lower dermis is composed mainly of neutrophils and eosinophils. A certain area of the lower dermis shows edema and capillary dilatation along with the mixed inflammatory cell infiltration, TVide excision of the indurated lesion including the tick was done. The clinical and hsitopathological findings of the tick bite was discussed.
Capillaries ; Dermis ; Dilatation ; Edema ; Eosinophils ; Humans ; Neutrophils ; Scrotum ; Skin ; Tick Bites* ; Ticks* ; Young Adult

No abstract available.
Asthma*

Respiratory effects of acute coronary embolism were studied in mongrel dogs. Coronary embolism was produced by Agress's method and respirtory effects were observed for two hours. In the experimental group, in which coronary embolism was produced, there were relative decreases in respiratory rate and arterial oxygen saturation along with relative increases in tidal volume, minute ventilation, ventilation equivalent and arteriovenous oxygen difference compared to those in the control group. However, differences in these various measurements between tow groups, those in tidal volume and arterial oxygen saturation, have greatly diminished in two hours. These facts suggest that changes in respiratory rate, minute ventilation, ventilation equivalent and arteriovenous oxygen difference in the experimental group are early but short-lasting responses to acute coronary embolism, whereas changes in tidal volume and arterial oxygen saturation occur early and last longer.
Animals ; Dogs ; Embolism* ; Oxygen ; Respiratory Rate ; Tidal Volume ; Ventilation

We recently encountered a case of pemphigus vulgaris, which was localized within the oral mucosa and esophagus. The patient was a 62-year-old women, who had had a few recurrent erosions on the oral mucosa for 1 year. Newly developed erythematous erosions on the esophagus appeared 7 days pre previously. Histopathological findings showed suprabasal blisters in the epithelium of the buccal and esophageal mucosa. On direct immunofluorescence, intercellular IgG and C3 bindings were found in the epithelium of the buccal mucosa. Treatment with oral steroids resulted in a remission of the lesions and the other skin lesions were not found for a period of 6 months.
Blister ; Epithelium ; Esophagus* ; Female ; Fluorescent Antibody Technique, Direct ; Humans ; Immunoglobulin G ; Middle Aged ; Mouth Mucosa* ; Mucous Membrane ; Pemphigus* ; Skin ; Steroids

Herpes gestationis(HG) characterized by the development of autoantibodies to the basement membrane is a pruritic bullous dermatosis of pregnancy and the postpartum period. HG is diag nosed on the basis of clinical findings, and a direct or indirect immunofluorescent test including an assaying for the denmonstration of IgG autoantibody in the serum. We report a case of herpes gestationis in Korea which showed a typical clinical and histopathologic findings accuring in a 30-year old primiparous patient. We could confirm the diagnosis in this case by in vitro C3 staining, and immunoblot analysis which revealed the presence of antibodies in her sertim against 180kD antigen of epidermal protein.
Adult ; Antibodies ; Autoantibodies ; Basement Membrane ; Diagnosis ; Female ; Humans ; Immunoglobulin G ; Korea ; Nose ; Pemphigoid Gestationis* ; Postpartum Period ; Pregnancy ; Skin Diseases

BACKGROUND: Esmolol is a short acting sympathetic beta receptor antagonist, and it was successfully applied to induced hypotension. Esmolol lowers blood pressure by decreasing cardiac output, and does not cause vasodilation. This property of esmolol may help to decrease bleeding during induced hypotension. In this study, we tried to elucidate the effect of esmolol on induced hypotension for total hip arthroplasty. METHOD: Twenty patients receiving total hip arthroplasty were randomly divided to two groups. Esmolol group (10 patients) received esmolol as a hypotensive agent, and sodium nitroprusside (SNP) group (10 patients) received SNP as a hypotensive agent. We measured arterial blood gas analysis, vital sign, amounts of bleeding, amounts of transfusion and administered fluid, and various laboratory findings. RESULTS: Induced hypotension was successfully performed in either esmolol and SNP group. Heart rate increased by SNP, and decreased by esmolol. There were no statistically significant differences between the two groups in amounts of bleeding, amounts of transfusion or administered fluid, and laboratory findings. Arterial oxygen tension was relatively constant in esmolol group, but decreased in SNP group. CONCLUSION: Esmolol can be used as a single hypotensive agent during induced hypotension without significant side effects during total hip arthroplasty.
Arthroplasty, Replacement, Hip* ; Blood Gas Analysis ; Blood Pressure ; Cardiac Output ; Heart Rate ; Hemorrhage ; Humans ; Hypotension* ; Nitroprusside* ; Oxygen ; Sodium* ; Vasodilation ; Vital Signs

No abstract available.
Genomic Library* ; Helicobacter pylori* ; Helicobacter*

The clinical and biological study for Sarcoptes scabiei from 66 scabies patients was performed form Nov. 1974 to April 1975. The diagnosis of these scabies patients were confirmed by method proposed by Muller et al. The results were as follows; 1) Male to female ratio is 5. 6: 1 in total patients and predominant age group is in 16~20 in both sexes(Table 1). 2) 50% of cases had family history of similar troubles and the duration of subjective symptom complaind at their first visit was 1~2 weeks in 20 cases, 3~4 weeks in 25, 2 months in 10, and over 3 months and unknown were 12. 3) Suspected sources of infestation were, 22 cases from one of their family members, 15 at hotel, 7 at boarding house, 2 at camping, 1 at military camp, 19 were unknown. 4) Distribution of burrows was hand(79.4%), wrist(12.4%), foot(3.1%), penis(2.6%) scrotum(2.1%) and axillary area(0.5%). Number of burrows was 1~2 in 61.4%, 3~4 in 19.3%, 5~6 in 5.3%, 7~8 in 1.8%, 9~10 in 5.3% and 10 in 7. 6%. 5) 44 patients (66.7%) were confirmed by finding of female mite and among them 50% had 1 female mite, 36.7% had 2, 6.8% had 3, 2.3% had 4 and 4.5% had 6. 6) 69 among total 79 female mites detected were found at burrow, 6 from papule and 4 from vesicle. Total 7 male mites were found from patients and 4 from papules and 2 from veside and 1 from pustule(Table 5) 7) From total 194 burrows examined 69 female mites (36.1%) were found and non of male mite were found. 8) Mean size of female mite(length*breadth) was 359.3u*266.5u, male mite 21.1u*160.9u, larva 131.8ux94.2u, egg with developing larva 167.3*93.6u, egg with developed larva 159.7u * 92.3u and scybala 18.7u x 12.3u. Sizes of egg with developing larva and egg with developed larva had no significant difference, statistically.
Camping ; Diagnosis ; Female ; Humans ; Larva ; Male ; Military Personnel ; Mites* ; Ovum ; Sarcoptes scabiei ; Scabies*

Perifollicular fibromas are very undsual adnexal tumor of the skin. Clinically, they are small firm akin colored or pinkish papules and usually located on the face and neck. We report a case of perifollicular fibroma which occurred in a 30-year-old woman, who had asymptomatic multiple small skin colored papules on the right side of her face for about 20 years. On physical examination, the papules were ferm and non-tender. The biopsy specimen demonstrated concentric proliferation of fibrous tissue surrounding hair follicles ad the collagen fibers within concentric fibrous sheaths surrounding hair follicles stained green with Masson's trichrome stain, which were quite typical for perifollicular fibroma. Because we could not find any epithelial proliferation in the serial sections, fibrofolliculoma could be ruled out. The skin lesions were removed by electrodesiccation and followed up for 5 months without recurrence.
Adult ; Biopsy ; Collagen ; Female ; Fibroma* ; Hair Follicle ; Humans ; Neck ; Physical Examination ; Recurrence ; Skin