1.A comparative study of the cranicial complex in korean with Down's syndrome.
Young Chul JANG ; Won Yong YANG ; Doo Hyung LEE
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1993;20(2):272-293
No abstract available.
Down Syndrome*
2.The diagnostic value of barium enema in acute appendicitis.
Dae Young WOO ; Nae Won JANG ; Ki Ho PARK
Journal of the Korean Surgical Society 1991;41(6):796-807
No abstract available.
Appendicitis*
;
Barium*
;
Enema*
3.Triennial Report of Endocrinology and Metabolism, 2015 to 2017.
Eun Jung RHEE ; Hey Yeon JANG ; Won Young LEE
Endocrinology and Metabolism 2018;33(2):195-201
No abstract available.
Endocrinology*
;
Metabolism*
4.Factors Affecting Acute Pain Management for Ureter Stone Patients in the Emergency Department.
Jong Won BAEK ; Won Young SUNG ; Jang Young LEE ; Won Suk LEE ; Young Mo YANG ; Sang Won SEO
Journal of the Korean Society of Emergency Medicine 2013;24(4):410-419
PURPOSE: The most important step for patients who come to the emergency department with ureter stones is acute pain management. There have been insufficient studies on what factors affect acute pain management for ureteral colic the most. In this study, patients with ureteral colic were divided into two groups: one group, in which the pain was first managed with an analgesic, and another group with unmanaged pain, to find factors that most affect additive analgesics administration for ureter stones. METHODS: There were 121 patients, eventually confirmed for the presence of ureter stones through a computed tomography CT scan, included in this study. When ureter stones were suspected after the initial patient evaluation, initial pain was assessed through numerical rating scale (NRS) and the first analgesic was administered once. Pain was reassessed through NRS after 30 minutes. At that time, if the pain was managed, the patient was assigned to Group 1. If the pain persisted, another analgesic was administered for the second and third time, and the patient was assigned to Group 2. Finally, ureter stones were identified through CT scan. RESULTS: There were 58 patients (47.9%) in Group 1 and 63 patients (52.1%) in Group 2. There were no statistically significant differences in average age, serum creatinine, size of ureter stone, and severity of hematuria between the two groups. The differences in NRS measured initially and after 30 minutes were statistically significant (7.6+/-1.4 vs. 8.6+/-1.2, p<0.001; 1.4+/-1.3 vs. 6.6+/-1.9, p<0.001, respectively). The presence of hydronephrosis and perirenal edema were also statistically significant (p<0.001, p=0.007). The affecting factor for the administration of additive analgesics was hydronephrosis (odds ratio 7.213, p<0.001). CONCLUSION: Hydronephrosis is an important factor in the treatment of patients with additive analgesics. It can also be used as a predictive index to assess the severity of pain in patients with ureter stones.
Acute Pain
;
Analgesics
;
Creatinine
;
Edema
;
Emergencies
;
Hematuria
;
Humans
;
Hydronephrosis
;
Renal Colic
;
Ureter
;
Urolithiasis
5.Serous Cystadenoma of the Pancreas: A case report.
Young Kyoung BAE ; Woo Young JANG ; Kyoung Chan CHOI ; Joon Hyuk CHOI ; Won Hee CHOI
Korean Journal of Pathology 1996;30(1):68-71
Serous cystadenoma of the pancreas, also known as microcystic adenoma or glycogen-rich cystadenoma, is an unusually benign tumor. It is usually large and composed microscopically of many small cysts lined by small, cuboidal or flattened cells containing abundant glycogen. It has been suggested that serous cystadenoma probably arise from the ductular cells or centroacinar cells. Herein, we report on a case of serous cystadenoma of the pancreas in a 55-year-old female. The tumor, measuring 13.5x11.5x10.0 cm, was located in the head of the pancreas and the cut surface revealed a sponge-like appearance due to innumerable tiny cysts containing clear serous fluid. Microscopic analysis showed cystic spaces lined by cuboidal cells with intracytoplasmic glycogen.
Female
;
Humans
;
Cysts
;
Adenoma
6.Epidural Butorphanol Reduces the Side Effects from Epidural Morphine after Cesarean Section.
Dong Gi JANG ; Won Young CHANG ; So Young YOON ; Kyung Bae KIM
Korean Journal of Anesthesiology 1997;33(2):297-303
BACKGROUND: Epidural morphine has side effects, especially pruritus, nausea, and vomiting. Butorphanol has been added in studies to reduce these side effects in post cesarean patients. The purpose of this study was to evaluate the side effects and analgesic efficacy when a combination of epidural morphine and butorphanol was administered in patients having combined local anesthetic and opioid epidural infusion. METHODS: Sixty patients having epidural anesthesia for cesarean section were randomly divided into two groups. Group M (n=30) received a bolus of 0.25% bupivacaine 4 ml, morphine 2 mg, and saline 0.75 ml, whereas group B (n=30) received a bolus of 0.25% bupivacaine 4 ml, morphine 2 mg, and butorphanol 1.5 mg (0.75 ml). Continuous epidural infusion was done by Two-day Infusor containing either 0.25% bupivacaine 75 ml, morphine 5 mg, and saline 20 ml in group M or 0.25% bupivacaine 75 ml, morphine 5 mg, butorphanol 4 mg (2 ml), and saline 18 ml in group B. We compared the side effect and analgesic effect of group M to those of group B for 2 days. RESULTS: The incidence of pruritus and vomiting were reduced significantly in group B (p<0.05). There were no significant differences between both groups in the incidence of nausea or other side effects as well as no differences in analgesic effect. CONCLUSIONS: We conclude that the addition of butorphanol to morphine in combined local anesthetic and opioid epidural infusion for postoperative analgesia decreases the occurrence of pruritus and vomiting without significant increase of other side effects and adverse effect on analgesia.
Analgesia
;
Anesthesia, Epidural
;
Bupivacaine
;
Butorphanol*
;
Cesarean Section*
;
Female
;
Humans
;
Incidence
;
Infusion Pumps
;
Morphine*
;
Nausea
;
Pregnancy
;
Pruritus
;
Vomiting
7.A Study on the Angle Between the Abdominal Aorta and the Superior Mesenteric Artery by 3D Image Reconstruction.
Young Ill JANG ; Won Jung KIM ; Young Nam HEO
Journal of Korean Society of Medical Informatics 2002;8(1):55-62
SMAS(Superior Mesenteric Artery Syndrome) is a disease caused by a chronic obstruction of the duodenum(transverse portion), which is hardly detectable. However, it is known that when the superior mesenteric artery and abdominal aorta form a narrow angle, that the transverse portion of the duodenum is pressed down between the superior mesenteric artery and the abdominal aorta, and that this can lead to obstruction of the duodenum. Measuring this angle is a complicated job using conventional angiography, and results often turns out to be inaccurate. In addition, no attempt has been made to determine the value of this angle in Koreans. In this study, we conducted abdominal CT angiography using MIP(maximum intensity projection) on patients with no clinical evidence of SMAS in order to determine the angle at which the superior mesenteric artery branches from the abdominal aorta by using PC based software(Rapidia ver. 1.2) for the image reconstruction. Accordingly, we found that the mean angle between the abdominal aorta and the superior mesenteric artery was 50.05+/-15.87 degrees on average, and that the angle in men(53.64+/-16.57 degrees) is higher than in women(46.46+/-14.98 degrees). We hope that the angles determined by our study will serve as an important indicator for detecting SMAS.
Angiography
;
Aorta, Abdominal*
;
Duodenum
;
Hope
;
Humans
;
Image Processing, Computer-Assisted*
;
Mesenteric Arteries
;
Mesenteric Artery, Superior*
;
Superior Mesenteric Artery Syndrome
;
Tomography, X-Ray Computed
8.A Study on the Angle Between the Abdominal Aorta and the Superior Mesenteric Artery by 3D Image Reconstruction.
Young Ill JANG ; Won Jung KIM ; Young Nam HEO
Journal of Korean Society of Medical Informatics 2002;8(1):55-62
SMAS(Superior Mesenteric Artery Syndrome) is a disease caused by a chronic obstruction of the duodenum(transverse portion), which is hardly detectable. However, it is known that when the superior mesenteric artery and abdominal aorta form a narrow angle, that the transverse portion of the duodenum is pressed down between the superior mesenteric artery and the abdominal aorta, and that this can lead to obstruction of the duodenum. Measuring this angle is a complicated job using conventional angiography, and results often turns out to be inaccurate. In addition, no attempt has been made to determine the value of this angle in Koreans. In this study, we conducted abdominal CT angiography using MIP(maximum intensity projection) on patients with no clinical evidence of SMAS in order to determine the angle at which the superior mesenteric artery branches from the abdominal aorta by using PC based software(Rapidia ver. 1.2) for the image reconstruction. Accordingly, we found that the mean angle between the abdominal aorta and the superior mesenteric artery was 50.05+/-15.87 degrees on average, and that the angle in men(53.64+/-16.57 degrees) is higher than in women(46.46+/-14.98 degrees). We hope that the angles determined by our study will serve as an important indicator for detecting SMAS.
Angiography
;
Aorta, Abdominal*
;
Duodenum
;
Hope
;
Humans
;
Image Processing, Computer-Assisted*
;
Mesenteric Arteries
;
Mesenteric Artery, Superior*
;
Superior Mesenteric Artery Syndrome
;
Tomography, X-Ray Computed
9.A clinical analysis of neurilemmoma originated from the head and neck.
Young Mook LIM ; Si Young WON ; Ki Sang RHA ; Jang Yoorl YOO ; Chan Il PARK
Korean Journal of Otolaryngology - Head and Neck Surgery 1991;34(4):769-774
No abstract available.
Head*
;
Neck*
;
Neurilemmoma*
10.Cyto - molecular Biologic Characterization of c - myc , erb B and EGF - Receptor in Squamous Cell Carcinoma.
Kyu Suk LEE ; Yoon Yae CHOI ; Joon Young SONG ; In Jang CHOI ; Sung Ik JANG ; Won Ki BAEK ; Min Ho SUH
Korean Journal of Dermatology 1994;32(2):223-233
BACKGROUND: Oncogenes and EGF-Receptor(EGFR) may be involved n different stages of the multistep carcinogenesis process. A specific pattern of karyotypic abnormalities in solid tumors can be detected by cytogenetic methods. OBJECTIVE: This study is intnded to observe the cytomolecular kiologic chracterization of c-myc, erb B and EGFR genes in squasnous cell carcinoma(SCC) of the skin and cervix. METHODS: We have eytogenet,ically examined the short-term culturs from SCC. The rearrangement, amplification or expressi.on of erb B, c-myc, and EGFR genes were studied by Southern blot, analysis of genomic DNA and by slot blot analysis of tota! RNA extracted from biopsies of normal skin and SCC tissues. EGFR expression was examined immunohistochemially using monoclonal antibodies and the localizat,ion of the c-myc oncogene mRNA by in situ hybridization. RESULTS: A remarkably structural aberration was del 6(q21-qter) counted 20 metaphases among 28 metaphases ana1yzed. In nunierical aberration, all chromosomes were lost or gained randomly. Amenploid including triploid and tetraploid were observed in 8 metaphases, 6 tumor cells contained marker chromosome. In Southern blot analysis, rearrangement and amglificaton of EGFR in primary squamous cell carcinoma of cervix uteri and skin respectively. In slot blot analysis, the levels of c-myc, erb B and EGFR mRNA increaaed respectively 3.5, 2.5 and 2.8 times in SCC when compared to normal tissues. In immunoperoxidase stain, EGFR was present, in SCC where keratinocytes with strong cyto-plasmic staining but no membr, line labelling, where as in normal skin the were primarily present in t,he membrane and cytoplasm of basal cells. In situ hybridization with c-myc cDNAs allowed detection of grains representative of biotin labelled cDNA-mRNA hybrids in the frozden section of SCC tissues. CONCLUSION: These results suggest that specific patterns of karyotypir abnormalites, rearrangement, or amplification of EGFR gene, and overexpression of oncogenes and EGFR gene may be associated with the carcinogenesis of SCC.
Antibodies, Monoclonal
;
Biopsy
;
Biotin
;
Blotting, Southern
;
Carcinogenesis
;
Carcinoma, Squamous Cell*
;
Edible Grain
;
Cervix Uteri
;
Cytogenetics
;
Cytoplasm
;
DNA
;
DNA, Complementary
;
Epidermal Growth Factor*
;
Female
;
Genes, erbB-1
;
In Situ Hybridization
;
Keratinocytes
;
Membranes
;
Metaphase
;
Oncogenes
;
RNA
;
RNA, Messenger
;
Skin
;
Tetraploidy
;
Triploidy