Multiple basal cell epithelioma on the face is a rare disease and the lesions are hard to indistinguish from multiple trichoepithelioma. The 15-year-old school girl has been suffered from multiple small pea-sized, slightly waxy appearing skin lesions on the face for 4 years. She has no history of arsenic ingestion; irradia tion and previous dermatoses. Physical examination and X-ray films (chest, mandibule and skull) showed no pathological findings. Biopsy findings revealed basal cell epithelioma cells.
Adolescent ; Arsenic ; Biopsy ; Carcinoma, Basal Cell* ; Eating ; Female ; Humans ; Physical Examination ; Rare Diseases ; Skin ; Skin Diseases ; X-Ray Film

Lidex(Fluacinonide) 0.05% in FAPG base is a new fluorinated topical corticosteroid. 30 patients with different steroid responsive dermatoaes were treated with 0. 05% Lidex. The diagnosis included atopic dermatitis, contact dermatitis, neurodermatitis, seborheic dermatitis, nummular eczema, psoriasis vulgaris, chronic eczema and pustulosis pahmaris et plantaris. In the majority of cases Lidex cream produced excellent to good result(70%) after unoccluded application 3 times daily for 10 days. Two patients complained burning or itching sensation after the initial application of Lidex. 0.05% Lidex was compared with 0. 25% Desoxymethasone cream and 0. 25% Fluocortolone cream and was found slightly more effective in Lidex.
Burns ; Dermatitis ; Dermatitis, Atopic ; Dermatitis, Contact ; Desoximetasone ; Diagnosis ; Eczema ; Fluocinonide* ; Fluocortolone ; Humans ; Neurodermatitis ; Pruritus ; Psoriasis ; Sensation

The diastolic retinal arterial blood pressure was measured by Ophthalmodynamometer in 15 patients of essential hypertension before and after the administration of Raudixin three times a days. The follow up period was 4 to 70 days. The average fall of the systolic brachial blood pressure was 38.1 mmHg(from 174.6 to 136.5 mmHg) 19 days after the treatment, whereas the average fall of the diastolic brachial blood pressure was 19.6 mmHg (from 166.6 to 94.7 mmHg) 24 days after treatment. A positive correlation was demonstrated between the retinal and brachial diastolic blood pressures prior to the treatment. The diastolic brachial blood pressure showed its fall only 15 days after treatment, the average fall being 17.1 mmHg. During this period of time, the average fall of the diastolic retinal arterial pressure was 10.2 mmHg. In 6 cases, the retinal arterial pressure didn't fall back to the normal valures and in 5 cases of Keith-Wagener group II, the retinal arterial pressure remained unchanged in spite of the treatment. The percentage ratio of the retinal to the brachial diastolic blood pressure remained stationary in 3 cases, rose in 4 cases. The number of cases which show fall in this ratio gradually increased and about 80% of the cases demonstrated definite fall one month after treatment. The retinal arterial pressure remained stationary during 2 weeks after treatment in 60% of the cases. The significant lowering of the retinal arterial blood pressure was observed only one month after treatment in the majority of cases. The retinal arterial pressure fell below normal range in no case.
Arterial Pressure* ; Blood Pressure ; Follow-Up Studies ; Humans ; Hypertension ; Rauwolfia* ; Reference Values ; Retinaldehyde*

Experimental ocular siderosis was induced in fourteen albino rabbits by the insertion of iron fragments through the scleral incision made at equatorial region. ERGs were recorded up to 30 days after the insertion of iron, both in scotopic and photopic conditions. Light stimulus used was electronic photoflash of 2 msec duration. The changes in the scotopic b-wave were classified into 3 types. The first type (4 eyes) showed gradual decrease finally attaining 54.6% of the original amplitude. The second type (3 eyes) showed supernormal b-wave during whole period of study, the increase reached 43.0% after 30 days. In the third type (6 eyes) the b-potential remained almost stationary. The scotopic a-wave changed in a similar way as the b-wave. Sometimes negative (-) type ERGs were recorded, especially during the falling stage of the b-potential. The photopic a- and b-waves changed almost parallel to the scotopic components. By slitlamp biomicroscopy and ophthalmoscopy, fibrous connective tissue proliferated around the iron fragments, never extending deep into the vitreous body. Fundi were well visible except the insertion site. Histological section revealed moderate scar tissue formation around the insertion site of iron, and mild visual cell and ganglion cell destructions.
Cicatrix ; Connective Tissue ; Ganglion Cysts ; Iron ; Ophthalmoscopy ; Rabbits ; Siderosis* ; Vitreous Body

The effects of Cryosurgery of the ciliary body on the aqueous humor dynamics of ten albino rabbits were studied by perfusion experiments. The cryo-probe (tip diameter, 3 mm) was frozen by dry ice and alcohol mixture and applied over the full circumference of the eye 2 mm from the limbus for 30 seconds. Eight applications were made in each eye. Intraocular pressure fell during the first 10 days after surgery, the amount of fall averaged 2.5 mmHg (12.6% of the pre-treatment level). Thereafter the intraocular pressure rose gradually in all eyes and reached almost to the original level 3 weeks after surgery. Facility of outflow changed inconsistently, showing no definite pattern. Aqueous flow showed significant reductions during the 2 to 3 weeks after treatment, then gradually recovered. There was no significant reduction in flow after the end of 3 weeks. No complications were encountered except mild iridocyclitis during the first week. The unsatisfactory outcome of this cryotherapy is considered to be due to the insufficient freezing of the ciliary body, and more applications is recommended in order to produce more sustained reduction of intraocular pressure.
Aqueous Humor ; Ciliary Body ; Cryosurgery ; Cryotherapy ; Dry Ice ; Freezing ; Intraocular Pressure ; Iridocyclitis ; Perfusion ; Rabbits*

Malignant melanoma is rare in Asian and one of the poorer prognostic disease. Approximately 25% of all patients with malignant melanoma has been occured at the site of pigmented leasion. Primary location of melanome on palm is known to be 1.3% which is rarer than that of the other site. This report is a case of 65 year old man who has a walnut sized bluish-black tumor(4*5*3cm) on left palm which developed from the brownish black spot. According to the patients statement the spot was started since childhood and gradually increase in size since last 5 years. The mass, however, was rapidly growing with superficial ulceration since 3 months previously. No metastatic skin leasion was found around the tumor mass and left upper extremity. There were no palpable tymphnodes in the left axillary and epitrochlear area. Skin biopsy specimen showed findings consistent with malignant melanoma and cell composition was predominant in the fusiform cell than the cuboidal cell, and exillary lymphnode showed only dermatopathic changes. Bone X-ray of left hand and chest X-ray showed no abnormal findings and metastatic sign. B-E(bellow elbow) smputations on left foream was performed. During postoperativ he has had general and no metastatic signs.
Aged ; Asian Continental Ancestry Group ; Biopsy ; Hand ; Humans ; Juglans ; Melanoma* ; Skin ; Thorax ; Ulcer ; Upper Extremity

This st;udy was to obtain psychosomatic factors influencing cause of chronic ureicaria and alopecia areata with comparison of dermatophytosis. This survey was carried out by Cornell Medical Index from March 1975 to- September 1976 on total 93 persons which constitute 22 chronic urticaria,38 alopecia areata and 33 dermatophytosis at; the out patient clinic of dermatology department of St. Mary hospital Findings were as follow: 1. The average numbr of complaints of over-all section was 47.36+26.89, the somatic section (31. 73+16. l4) and the psychic (l5. 64+-12. 64) in the chranic urticaria. The average number of complaints of over-all section was R8.50+20.89, the somatic section (22. 63+-13. 10) and psychic section (15. 87+-9. 90) in the alopecia areata, For the control, over-all section was 25. 18+18. 87, the somatic section (16. 30+l2. 38) and the psychic(8. 88+8. 96) in the dermatophytosis. Consquently, there was an increased number of complaints in the group of chronic urticaria and alopecia areata than the control group. 2. There was increased complaint of both the somatic and psychic section in the chronic urticaria. 3. There was increased complaint of psychic section than the somatic section in the alopecia areata.
Alopecia Areata* ; Alopecia* ; Cornell Medical Index* ; Dermatology ; Humans ; Tinea ; Urticaria*

No abstract available.

This report offers descriptive data about the drugs utilized in outpatient department (OPD) of Yeungnam University Hospital (YUH) in the period of March to August in 1985. The data in this report were produced by the computerized totalization of the number of mentions of individual drugs included in the prescriptions. The 100 drug entries that were most frequently recorded are listed in rank order. The listing is arbiturarily restricted to the drugs that were prescribed as single preparations, the drugs of basis of compound preparations and the drugs of adjuvant or corrective of compound preparations that have significant therapeutic effects either by generic names. And in addition, the listing also involves the compound preparations used in relatively large frequency, and the individual components of which have the unique pharmacological actions each other by proprietary names. And all routes of administrations were allowed. The 10 drugs most frequently named are diazepam, aluminum compounds, acetaminophen, isoniazid, metoclopramide, polaramine®, carboxymethylcystein, ephedrine, codeine and caroverine in order. The 521, 855 drug mentions listed as above are described by the chief therapeutic usage that each is intended to apply generally. The drugs which account the largest proportion of total mentions were those acting on the central nervous system (20.57%), including tranquillizers and sedative hypnotics (11.71%), analgesic antipyretics (5.55%), antidepressants (2.15%) etc. Gastrointestinal drugs and smooth muscle preparations (18.64%) included antacids and antiulcer drugs (9.24%), antiemetics (3.57%), spasmolytics (3.14%) and others. Respiratory drugs (16.11%) included expectorants and cough preparations (10.99%) and bronchodilators (5.12%). Chemotherapeutic agents (15.12%) included the antiTbc drugs (7.09%) most frequently, and the penicillins (3.33%) accounted the largest proportion among the antibiotics. Cardiovascular drugs (5.64%) included cardiac drugs and coronary vasodilator (4.12%) and antihypertensives and vasodilators (1.06%). And antiinflammatory drugs (4.33%), vitamins of single preparations (3.76%), hormones and their antagonists (3.29%), common cold preparations (3.12%), diuretics (2.81%), drugs supporting liver function (2.02%), drugs affecting autonomic nervous system (1.89%) including antiglaucomas, atropine and cerebral vasodilators, antihistamine drug (1.02%) and disinfectants (0.74%) were following in order. The data in the report were compared to those reported by H. Koch, et al. in United States (US), 1981 as “Drugs Most Frequently Used in Office Practice : National Ambulatory Medical Case Survey, 1981.” Cardiovascular drugs prescribed in YUH were much less in proportion than in US (10.56%), but gastrointestinal drugs accounted the larger proportion than in US (3.72%). Expectorants and preparations in YUH also accounted the larger proportion than in US (2.74%). In conclusion, in the period of March to August, 1985, OPD of YUH prescribed the CNS drugs including diazepam most frequently, and gastrointestinal, respiratory and chemotherapeutic drugs in next orders. It is supposed that the eating habits of Koreans and a unique atmospheric condition in Taegu as a basin were some important factors that affected the proportions of drugs acting on gastrointestinal and respiratory tracts.
Acetaminophen ; Aluminum Compounds ; Antacids ; Anti-Bacterial Agents ; Antidepressive Agents ; Antiemetics ; Antihypertensive Agents ; Antipyretics ; Atropine ; Autonomic Nervous System ; Bronchodilator Agents ; Cardiovascular Agents ; Central Nervous System ; Codeine ; Common Cold ; Cough ; Daegu ; Diazepam ; Disinfectants ; Diuretics ; Eating ; Ephedrine ; Expectorants ; Gastrointestinal Agents ; Humans ; Hypnotics and Sedatives ; Isoniazid ; Liver ; Metoclopramide ; Muscle, Smooth ; Outpatients ; Parasympatholytics ; Penicillins ; Prescriptions ; Respiratory System ; Therapeutic Uses ; United States ; Vasodilator Agents ; Vitamins

Vitreous hemorrhages of white rabbit eyes were obtained by the following three methods and their ultrasonographies were checked several times for four weeks. 1 st group: fresh human blood was injected into the vitreous cavity through the sclera, 2 nd group: oxalated human blood was injected into the vitreous cavity in the same way, 3 rd group: a 26 gauge needle was inserted into the vitreous cavity and retinal vessels were mechanically ruptured to cause vitreous hemorrhage. Ultrasonography of the above groups revealed no definite differences between groups, but a high echo from the vitreous hemorrhages in initial stage changed to several low echoes in later stage. This fact was well matched with funduscopic observation for gradual absorption of the vitreous hemorrhage.
Absorption ; Humans ; Needles ; Retinal Vessels ; Sclera ; Ultrasonography* ; Vitreous Hemorrhage