The purpose of this study was to compare the microleakage of the IPS Empress ceramic crown according to 1) margin types such as rounded shoulder and bevel, 2) margin locations such as enamel and dentine, 3) resin cement types such as Variolink and Bistite. For this study, 80 extracted premolar teeth were used. After 10 experimental dies were prepared for each group, the IPS Empress ceramic crowns were fabricated on the dies and cemented with one of two types of resin cement. After 1,000 cycles of thermal changes were given with the thermocycling unit, each specimen was sectioned with a low speed diamond saw in both the buccolingual and the mesiodistal direction. The microleakage was then measured with a stereo microscope. The obtained results were as follows : 1. Every experimental group showed microleakage. The microleakage of the crowns which had a rounded shoulder on enamel cemented with Variolink was the lowest of all. The resulting rank of the mean microleakage was rounded shoulder on enamel using Variolink(0.601mm), rounded shoulder on enamel using Bistite (0.794mm), bevel on enamel using Variolink (0.826mm), rounded shoulder on dentine using Variolink(1.054mm), bevel on enamel using Bistite(1.087mm), rounded shoulder on dentine using Bistite(1.176mm), bevel on dentine using Variolink(1.258mm), and bevel on dentine using Bistite(1.467mm). 2. The statistically significant differences in the microleakage were found in 4 cases: rounded shoulder on enamel using Variolink and bevel on dentine using Variolink, rounded shoulder on enamel using Variolink and bevel on dentine using Bistite, rounded shoulder on enamel using Bistite and bevel on dentine using Bistite, bevel on enamel using Variolink and bevel on dentine using Bistite. 3. The microleakage of rounded shoulder finish line was lower than that of bevel finish line. The statistically significant differences were found with respect to the type of finish lines. 4. The microleakage of the finish line on enamel was lower than that of finish line on dentine. The statistically significant differences were found with respect to the location of the finish lines. 5. The microleakage of the Variolink cement was lower than that of the Bistite cement. The statistically significant differences were found with respect to the resin cements.
Bicuspid ; Ceramics* ; Crowns* ; Dental Enamel ; Dentin ; Diamond ; Resin Cements* ; Shoulder ; Tooth

No abstract available.
Humans ; Twins*

Intracranial hypoglossal neurinomas are rare and only about fifty cases have been reported worldwidely. They usually present with hypoglossal nerve palsy preoperatively. The authors experienced, however, two cases of intracranial hypoglossal neurinomas without preoperative hypoglossal nerve palsy. One patient was operated using transcondylar retrosigmoid approach with C1 laminectomy and the other using midline suboccipital craniectomy with C1 laminectomy. Postoperatively hypoglossal nerve palsy was developed in both cases. Absence of preoperative hypoglossal palsy seemed to be related to somewhat different growth pattern in these two cases. When the tumor shows typical radiological findings of hypoglossal neurinoma, it must be included in differential diagnosis despite absence of preoperative hypoglossal nerve palsy.
Diagnosis, Differential ; Humans ; Hypoglossal Nerve Diseases* ; Hypoglossal Nerve* ; Laminectomy ; Neurilemmoma* ; Paralysis

OBJECTIVES: Nurses working in a hospital operate in a special environment where patients require a 24-hour day service. In order to meet the need for manpower, nurses in the wards, ICU, and ER work in 3 shifts per day. This study was designed to evaluate their sleeping patterns and the factors that influence them. METHODS: The subjects were 114 female nurses working at a University Hospital in Kyungi-do. To evaluate their sleeping pattern, a survey containing 11 questions was used. Their were differentiated into insomnia, sleep deprivation, daytime sleepiness, and snoring. Statistical analysis was conducted with independent t test, chi-square test and analysis of covariance. RESULTS: A statistical difference was found between shiftworkers and nonshiftworkers, in terms of sleep initiation time (p<0.05). The occurrences of insomnia, sleep deprivation, daytime sleepiness and snoring differed between the two groups, but not significantly. CONCLUSIONS: Of the numerous factors affecting sleeping patterns, shiftwork has the most deteriorative effect.
Female ; Humans ; Sleep Deprivation ; Sleep Initiation and Maintenance Disorders ; Snoring

OBJECTIVE: To assess the 10-year cumulative survival outcome of polymyositis (PM) and dermatomyositis (DM) as well as the factors associated with the the outcome. METHODS: Eighty five patients with PM and twenty one patients with DM were diagnosed at our university medical center between 1997 and 2007. Thirty six patients with PM and 13 patients with DM were followed up until death or until the end of January, 2008. Gender, age, AST, ALT, CPK, LDH, ESR, CRP, aldolase, drugs of therapy, combined ILD, and cancer, and duration of remission after therapy were assessed as prognostic factors of death by the Kaplan-Meier curve and Cox regression model. RESULTS: The respective 10-year survival rate for PM and DM was 80.8% (95% confidence interval (CI): 73.3~87.2) and 55.9% (95% CI: 40.7~71.1), respectively. The median survival for PM and DM was 11.3 years (95% CI: 9.8~12.9) and 7.0 years (95% CI: 3.6~10.5), respectively. Compared to DM patients, the subjects with PM had a 167.26 fold (95% CI: 7.59~3683.19) combined ILD adjusted risk of mortality (p<0.05) and no other individual factor reached significance as a predictor of death. However, cancer had a hazard ratio (HR) of 17.00 (95% CI: 1.06~281.79) and 2.45 (95% CI: 0.78~12.45) for death in the PM and DM group, respectively. CONCLUSION: According to an analysis of the survival and its prognostic factors in patients with PM and DM, ILD is a risk factor for mortality in PM and cancer was risk factor for mortality in both PM and DM.
Academic Medical Centers ; Dermatomyositis ; Fructose-Bisphosphate Aldolase ; Humans ; Myositis ; Polymyositis ; Risk Factors ; Survival Rate

The clinical manifestations of antisynthetase syndrome are severe interstitial pneumonitis, mild polyarthritis, and myositis. This disease is accompanied by anti-Jo-1 antibodies and anti-Ro/SSA antibodies and occasionally by the concurrence of anti-Jo-1 and anti-Ro/SSA antibodies, which leads to a more severe form of interstitial lung disease. In this case, the patient was transferred to our hospital because of pulmonary fibrosis with myositis and diagnosed with antisynthetase syndrome and the concurrence of anti-Jo-1 with anti-Ro/SSA antibodies. He was refractory to glucocorticoids, and developed leucopenia and thrombocytopenia. He was treated with rituximab infusions, but the interstitial pneumonitis progressed very rapidly and he died.
Antibodies ; Antibodies, Monoclonal, Murine-Derived ; Arthritis ; Glucocorticoids ; Humans ; Lung Diseases, Interstitial ; Myositis ; Pulmonary Fibrosis ; Rituximab ; Thrombocytopenia

Adult onset Still's disease (AOSD) is a systemic inflammatory disorder of unknown etiology. AOSD is characterized by fever, arthralgia, salmon-colored skin rash, hepatosplenomegaly and its laboratory abnormalities include leukocytosis, elevated liver enzyme, negative autoantibody, and hyperferritinemia. The clinical course varied and severe complicated conditions, such as hemophagocytic syndrome, and disseminated intravascular coagulation, occurred occasionally. Such a complication is accompanied with hemolytic anemia and lead to be a fatal course. We report the first case of AOSD with hemolytic anemia, which improved with high dose steroid therapy.
Adult ; Anemia, Hemolytic ; Arthralgia ; Disseminated Intravascular Coagulation ; Exanthema ; Fever ; Humans ; Leukocytosis ; Liver ; Lymphohistiocytosis, Hemophagocytic ; Still's Disease, Adult-Onset

Adult onset Still's disease (AOSD) is a systemic inflammatory disorder of unknown etiology. AOSD is characterized by fever, arthralgia, salmon-colored skin rash, hepatosplenomegaly and its laboratory abnormalities include leukocytosis, elevated liver enzyme, negative autoantibody, and hyperferritinemia. The clinical course varied and severe complicated conditions, such as hemophagocytic syndrome, and disseminated intravascular coagulation, occurred occasionally. Such a complication is accompanied with hemolytic anemia and lead to be a fatal course. We report the first case of AOSD with hemolytic anemia, which improved with high dose steroid therapy.
Adult ; Anemia, Hemolytic ; Arthralgia ; Disseminated Intravascular Coagulation ; Exanthema ; Fever ; Humans ; Leukocytosis ; Liver ; Lymphohistiocytosis, Hemophagocytic ; Still's Disease, Adult-Onset

OBJECTIVES: Blood pressure variation (BPV) and metabolic syndrome is an independent risk factor for cardiovascular events. Ambulatory blood Pressure (ABP) has been shown to be more closely related to cardiovascular events in hypertensive patients than conventional office BP (OBP). Using both OBP and ABP, 4 groups of patients were identified: (1) normotensive patients (NT); (2) white coat hypertensives (WCHT); (3) masked hypertensives (MHT); and (4) sustainedhypertensives (SHT). We investigated the significance of BPV and metabolic risks of these 4 groups. METHODS: This study is a retrospective analysis of patients between January 2008 and May 2013. Echocardiography and 24 hour ABP monitoring were performed. RESULTS: BMI was significantly higher in the MHT compared with the NT. There were progressive increases in fasting glucose level from NT to WCHT, MHT, and SHT.MHT and SHT had higher 24h and nighttime BPV than NT.MHT was significantly related with BMI (r = 0.139, P = 0.010), creatinine (r = 0.144, P = 0.018), fasting glucose (r = 0.128, P = 0.046), daytime systolic BPV (r = 0.130, P = 0.017), and daytime diastolic BPV (r = 0.130, P = 0.017). Dyslipidemia (r = 0.110, P = 0.043), nighttime systolic BPV (r = 0.241, P < 0.001) and nighttime diastolic BPV (r = 0.143, P = 0.009) shown correlation with SHT. In multivariate logistic regression, MHT was independently associated with Body mass index (OR 1.086, 95% CI 1.005–1.174, P = 0.038) and creatinine (OR 1.005, 95% CI 1.001–1.010, P = 0.045). CONCLUSIONS: BPV and metabolic risk factors were found to be greater in MHT and SHT compared with NT and WCHT. This suggests that BPV and metabolic risks may contribute to the elevated cardiovascular risk observed in patients with MHT and SHT.
Blood Pressure* ; Body Mass Index ; Creatinine ; Dyslipidemias ; Echocardiography ; Fasting ; Glucose ; Humans ; Hypertension* ; Logistic Models ; Masked Hypertension ; Masks ; Retrospective Studies ; Risk Factors* ; White Coat Hypertension

BACKGROUND/AIMS: Minor disorders of peristalsis are esophageal motility disorders categorized by the Chicago Classification (CC), version 3.0, which was announced in 2014. This study evaluated the efficacy of anti-reflux therapy in patients with minor peristaltic disorders. METHODS: Patients with minor peristaltic disorders in accordance with CC v3.0 were included. We reviewed the medical records of patients with esophageal high-resolution manometry findings, and investigated the demographic and clinical information as well as the medical therapy. Thereafter, the response to treatment was assessed after at least 4 weeks of treatment. RESULTS: A total of 24 patients were identified as having minor disorders of peristalsis from January 2010 to December 2015. The mean follow-up period was 497 days, and there were 17 patients (70.8%) patients with ineffective esophageal motility. In terms of anti-reflux therapy, proton pump inhibitors (PPIs) with prokinetic agents and PPIs alone were prescribed in 19 patients (79.2%) and 5 patients (20.8%), respectively. When the rate of response to the treatment was assessed, the responders rate (complete+satisfactory [≥50%] responses) was 54.2% and the non-responders rate (partial [<50%]+refractory responses) was 45.8%. Patients in the responder group were younger than those in the non-responder group (p=0.020). Among them, 13 patients underwent 24-hour multichannel intraluminal impedance-pH, and 10 patients (76.9%) were pathologic gastroesophageal reflux. CONCLUSIONS: The majority of esophageal minor peristaltic disorders were accompanied by gastroesophageal reflux, and therefore, they might respond to acid inhibitor. Further well-designed, prospective studies are necessary to confirm the effect of anti-reflux therapy in these patients.
Classification ; Esophageal Motility Disorders ; Follow-Up Studies ; Gastroesophageal Reflux ; Humans ; Manometry* ; Medical Records ; Peristalsis* ; Prospective Studies ; Proton Pump Inhibitors ; Proton Therapy ; Treatment Outcome