No Abstract Available.
Retinal Detachment* ; Retinal Perforations* ; Retinaldehyde*

No abstract available.
Travel Medicine

Topical fluorouracil therapy is an advanced treatment for actinic keratoses, Bowen's disease, multiple basal cell epithelioma and other precancerous skin lesions. Because of extensive and frequent use of 5-fluorouracil(5 F-U) cream, some untoward effects, mostly allergic contact dermatitis and irritation dermatitis, can be anticipated. We have experienced a case of crural ulcer after accidental application of 5 F-U cream for treating the tinea cruris at drug store. The patient was 21 year oid man who had suffered from erythema, erosion and shallow ulceration with oozing, serosanguinous discharge, buming and stinging sensation on the both groins and its adjacent area of the scrotum. The skin lesion was not well responded to topical corticosteroid but controlled by wet dressing and zinc oxide lotion within 10 days of hospitalization. At the 20th hospital day, the skin was healed with remained follicular hyperpigmentation. A few days later, the tinea cruris was confirmed by direct microsopic examination and culture. Generally, topical 5 F-U spares normal cell, while selectively destroying the more rapidly proliferating celI, but there are some possible factors to induce destruction of non-proliferating cell in the highly penetrating area The skin penetration can be different depending upon the anatomical location.
Bandages ; Bites and Stings ; Bowen's Disease ; Carcinoma, Basal Cell ; Dermatitis ; Dermatitis, Allergic Contact ; Erythema ; Fluorouracil ; Groin ; Hospitalization ; Humans ; Hyperpigmentation ; Keratosis, Actinic ; Scrotum ; Sensation ; Skin ; Tinea ; Ulcer* ; Zinc Oxide

No abstract available.
Osteotomy* ; Rabbits*

No abstract available.
Osteotomy* ; Rabbits*

No abstract available.
Heart Valve Diseases* ; Heart Valves* ; Heart*

No abstract available.
Animals ; Cadmium Poisoning* ; Cadmium* ; Olfactory Mucosa* ; Rats*

Frason' a new topical steroid ointment containing 0.05% 17-desoxymethason and 0.5 % framycetin, was in trial for several kinds of dermatoses. Total 40 patients including 8 cases of contact dermatitis, 6 seborrheic dermatitis, 4 atopic dermatitis, 4 pityriasis rosea, 4 acne vulgaris, 3 nummular eczema, 3 psoriasis vulgaris, 3 pustulosis palmaris et plantaris and 1 folliculitis were treated with Frason', and the results were as follows. 1) 29 patients revealed excellent or good therapeutic effects (72.5%) with unoccluded application of Frason ointment, 2 or 3 times daily, among the 40 patients. 2) In comparison with the 0.05% Frason' ointment and the 0.05% betamethasone- gentamycin cream, the 0.05% Frason' ointment was found to be slightly more effeetive in the aspect of anti-inflammatory and anti-bacterial action. 3) W/0 base of Frason' ointment had slightly irritating reaction compare to O/W base of betamethasone cream, There was no side effect except 1 patient who complained of buming sensation after initial application of Frason ointment.
Acne Vulgaris ; Betamethasone ; Dermatitis, Atopic ; Dermatitis, Contact ; Dermatitis, Seborrheic ; Eczema ; Folliculitis ; Framycetin ; Gentamicins ; Humans ; Pityriasis Rosea ; Psoriasis ; Sensation ; Skin Diseases

Epidermal nevus syndrome, which used to combine congenital abnormalities of the central nervous and skeletal system and others, are not ingrequently encountered. Until now fer cases of epidermal nevus with intemal malignancy were reported in the literatures, Since the report on this epidermal nevus associated with intemal malignancy, the newer finding was interested by dermatologist. A case of 3 and half months old boy who had nevus unius lateris and retroperitoneal leiomyosarcoma since at birth was seen at St. Mart's Hospital. He did not mongolian and cafe au lait spots on the vack which seemed to be a characteristicaign of epidermal nevus syndrome, His developmenta percmtile was 25 of his matched age group. He was bome with spontaneous normal delibery in the hospital. His parents were relatively healthy and his morher had no history of any kind of medicine taken during the pregnancy. There were no family history of epidermal nevuys like skin lesions and hereditary disorders.
Cafe-au-Lait Spots ; Congenital Abnormalities ; Humans ; Leiomyosarcoma ; Male ; Nevus* ; Parents ; Parturition ; Pregnancy ; Skin

Dissecting aortic aneurysm is an emergency condition which requires prompt diagnosis and management. From January 1992 to December 1996, 54 patients were admitted to our department. Patients were categorized according to the Stanford classification of aortic dissection and investigation of the clinical records utilized the retrospective method. Male constituted the majority, according for 38(70.4%) of the total number of patients, whereas females accounted for 16(29.6%). Mean age was 52.1+/-2.2 years old (range:25~82). Clinical findings included chest pain in 46 cases(85.2%), renal failure in 11(20.4%), aortic insufficiency in 10(18.5%) and stroke in 9(16.7%). Predisposing factors were hypertension in 48 cases(88.9%), Marfan's syndrome in 5(9.3%) and diabetes mellitus in 1(1.8%). 21 patients(type A:12, type B:9) underwent surgical treatment. There were three(2 in type A and 1 in type B) deaths in the surgical treatment group and nine(5 in type A and 4 in type B) deaths in the medical treatment group. These results reflect our current policy in the management of dissecting aortic aneurysm.
Aortic Aneurysm* ; Causality ; Chest Pain ; Classification ; Diabetes Mellitus ; Diagnosis ; Emergencies* ; Emergency Service, Hospital* ; Female ; Humans ; Hypertension ; Male ; Marfan Syndrome ; Renal Insufficiency ; Retrospective Studies ; Stroke