1.A roentgenocephalometric study on soft tissue profile changes in pre-post treatment of Angle's Class II division I malocclusion.
Korean Journal of Orthodontics 1983;13(2):193-198
No abstract available.
Malocclusion*
2.A study of diagnostic value on fine needle aspiration cytology of the breast masses.
Korean Journal of Cytopathology 1993;4(1):1-8
No abstract available.
Biopsy, Fine-Needle*
;
Breast*
3.Radiologic evaluation of ankle fractures
Won Wha LEE ; Hae Won PARK ; In Kyu PARK
Journal of the Korean Radiological Society 1983;19(4):851-856
The injuries to the ankle joint complex can cause not only bony fractures but also assoicated ligamentrupture. Understanding of the mechanism of those injuries is important for the radiologist to give moreinformation to the orthopedist to identify ligament injuries and then to fix the fractures. In 1948, Lauge-Hansendevised a classification of ankle fractures based on the position of the foot and direction of injuring force atthe time of injury. On the vasis of location and appearance of the fibular fracture, 4 type of injuries areidentified; pronation-abduction (PA), prnation-external rotation (PER), supination-adduction (SA), andsupination-external rotation (SER). 60 cases of ankle fracures treated at Kyung Pook, National University Hospitalfrom Jan, 1973 to Dec. 1982 were analized and classified. The results are as follows; 1. Male was more frequetnlyaffected than female and the sex ratio was 4:1. 2. The most commonly affected age group was 20's. 3. Right sidewas more frequetnly affected than left. 4. Among 4 types, the most common was SER type (33.3%) and next were PER(30.3%), SA(16.7%), and PA(13.3%) types.
Ankle Fractures
;
Ankle Joint
;
Ankle
;
Classification
;
Female
;
Foot
;
Humans
;
Ligaments
;
Male
;
Sex Ratio
4.Malignant Mixed Mesodermal Tumors of Ovary: 3 cases report.
Dong Won KIM ; Tae Jung KWON ; Dong Wha LEE
Korean Journal of Pathology 1988;22(2):169-179
Malignant mixed mesodermal tumor (MMMT) of the ovary is endometrioid tumor containing epithelial and mesenchymal components. The mesenchymal component may be homologous, in which case the term carcinosarcoma is often used, or heterologous, containing cartilage, striated muscle, osteoid, bone, or fat, or combination of these elements. MMMT usually afflicts the postmenopausal woman and occurs more often in the nulliparous female. The disease is usually advanced (stage III) when diagnosed. Cliniopathologic data were presented for 3 cases of MMMT of the ovary with review of literatures. Clinical history substantiated previous reports in postmenopausal women wit this tumor. Symptoms were the same as for ovarian malignancy in general. All the patients presented wit stage II disease, according to the International Federation fo Gynecology and Obstetrics (FIGO) classification. Two patients died of tumor 4 and 10 months after operation, respectively. One patient had been alive at 2 months after operation. None of 3 cases demonstrate evidence of endometriosis in the remaining ovaries. Microscopically, periodic acid-Schiff (PAS)-positive, diastase-resistant hyaline droplets were found frequently in undifferentiated mesenchymal stroma and epithelial structures. The clinical significance and origin of the hyaline droplets in MMMT should be further explored.
Female
;
Humans
5.Immunohistochemical Study on the Expression of Mutated p53 Protein and Bcl-2 Protein in Melanocytic Lesions of Skin.
Wha Jin LEE ; Joon Hyuk CHOI ; Won Hee CHOI
Korean Journal of Pathology 1997;31(2):112-120
To investigate the immunohistochemical expression of mutated p53 protein and bcl-2 protein in the cutaneous melanocytic lesion, 15 cases of compound nevus, 10 cases of congenital melanocytic nevus, 15 cases of primary malignant melanoma(4 cases less than 1.5 mm thick and 11 cases more than 1.5 mm thick), and 10 cases of metastatic malignant melanoma(7 cases in lymph node and 3 cases in soft tissue) were examined. All cases of compound nevi and of congenital melanocytic nevi showed no immunoreactivity for p53 protein. p53 protein overexpression was observed in 75%(3/4) wth primary malignant melanoma less than 1.5 mm thick, 81%(9/11) with primary malignant melanoma more than 1.5 mm thick, and 100%(10/10) with metastatic malignant melanoma. The difference in p53 protein overexpression was statistically significant between benign nevi and malignant melanoma(p<0.01). Bcl-2 protein expression was observed in 73%(11/15) with compound nevus, 70%(7/10) with congenital melanocytic nevus, 75% (3/4) in primary malignant melanoma less than 1.5 mm thick, 54%(6/11) with primary malignant melanoma more than 1.5 mm thick, and 40%(4/10) with metastatic malignant melanoma. These findings suggested that mutation of p53 gene may be an important mechanism in the development of malignant melanoma. Although bcl-2 protein was expressed in cutaneous melanocytic lesion, no correlation was found between p53 protein and bcl-2 protein expression in malignant melanoma.
Genes, p53
;
Lymph Nodes
;
Melanoma
;
Nevus
;
Nevus, Pigmented
;
Skin*
6.Immunohistochemical Study on the Expression of Mutated p53 Protein and Bcl-2 Protein in Melanocytic Lesions of Skin.
Wha Jin LEE ; Joon Hyuk CHOI ; Won Hee CHOI
Korean Journal of Pathology 1997;31(2):112-120
To investigate the immunohistochemical expression of mutated p53 protein and bcl-2 protein in the cutaneous melanocytic lesion, 15 cases of compound nevus, 10 cases of congenital melanocytic nevus, 15 cases of primary malignant melanoma(4 cases less than 1.5 mm thick and 11 cases more than 1.5 mm thick), and 10 cases of metastatic malignant melanoma(7 cases in lymph node and 3 cases in soft tissue) were examined. All cases of compound nevi and of congenital melanocytic nevi showed no immunoreactivity for p53 protein. p53 protein overexpression was observed in 75%(3/4) wth primary malignant melanoma less than 1.5 mm thick, 81%(9/11) with primary malignant melanoma more than 1.5 mm thick, and 100%(10/10) with metastatic malignant melanoma. The difference in p53 protein overexpression was statistically significant between benign nevi and malignant melanoma(p<0.01). Bcl-2 protein expression was observed in 73%(11/15) with compound nevus, 70%(7/10) with congenital melanocytic nevus, 75% (3/4) in primary malignant melanoma less than 1.5 mm thick, 54%(6/11) with primary malignant melanoma more than 1.5 mm thick, and 40%(4/10) with metastatic malignant melanoma. These findings suggested that mutation of p53 gene may be an important mechanism in the development of malignant melanoma. Although bcl-2 protein was expressed in cutaneous melanocytic lesion, no correlation was found between p53 protein and bcl-2 protein expression in malignant melanoma.
Genes, p53
;
Lymph Nodes
;
Melanoma
;
Nevus
;
Nevus, Pigmented
;
Skin*
7.A Case of Desmoplastic Fibroma of the Mandible.
Dong Won KIM ; Tae Jung KWON ; Dong Wha LEE
Korean Journal of Pathology 1988;22(3):340-347
A case of desmoplastic fibroma of mandible in a 18 years old woman is presented. She had complained progressive swelling of right mandible for 4 years. Radiographically, a multilocular radiolucent of right hemimandibulectomy showed multinodular external surface without cortical destruction. Cut surfaces revealed grayish white, fibrous homogeneous appearance with firm consistency, sparing head portion. The maximum diameter of the tumor was 13 cm. Microscopically, the tumor was composed of interlacing bundles of monomorphic spindle-shaped cells with abundant intercellular collagen. Ultrastructurally, most tumor cells were fibroblastic-like cells with abundant RER and cytoplasmic fibrils, but a few disclosed transition to myofibroblasts. However, no fully developed myofibroblasts were seen.
Female
;
Humans
8.A Case of Desmoplastic Fibroma of the Mandible.
Dong Won KIM ; Tae Jung KWON ; Dong Wha LEE
Korean Journal of Pathology 1988;22(3):340-347
A case of desmoplastic fibroma of mandible in a 18 years old woman is presented. She had complained progressive swelling of right mandible for 4 years. Radiographically, a multilocular radiolucent of right hemimandibulectomy showed multinodular external surface without cortical destruction. Cut surfaces revealed grayish white, fibrous homogeneous appearance with firm consistency, sparing head portion. The maximum diameter of the tumor was 13 cm. Microscopically, the tumor was composed of interlacing bundles of monomorphic spindle-shaped cells with abundant intercellular collagen. Ultrastructurally, most tumor cells were fibroblastic-like cells with abundant RER and cytoplasmic fibrils, but a few disclosed transition to myofibroblasts. However, no fully developed myofibroblasts were seen.
Female
;
Humans
9.Clinical Study for Achilles Tendon Rupture
Wha Hyun PARK ; Won Gap LEE ; Hong Woo KIM
The Journal of the Korean Orthopaedic Association 1980;15(2):321-328
Achilles tendon is the most powerful tendon of the body and increases efficiency in weight bearing and walking capability. Since pares' report about the rupture of the Achilles tendon many authors have reported various causes, diagnostic and therapeutic methods. Most of the authors emphasized the early diagnosis and treatment resulted in good prognosis. There are many methods for the diagnosis of the Achilles tendon, roentgeography, angiography, electromyography, histologic examination and Thompsons test. The causes of the rupture of the Achilles tendon are direct and indirect injury. The two methods of treatment are conservative management and surgical treatment. Whether the cause of the injury is direct or indirect, restoration of function after treatment must be emphasized and the proper method of treatment must be determined by the degree of injury. Clinical analysis was done on 15 cases of Achilles tendon rupture treated at Orthopedic Department of Capital Armed Forces General Hospital from Oct. 1973 to Oct. 1978 with the following results. 1. In sex distribution, there were 13 male cases and 2 female cases and the age range of 20 to 30 years old was the most frequent (67%). 2. There was no difference In frequency between the right and the left side. 3. Achilles tendon rupture was two times more frequent in indirect cause than direct cause, especially after falling from heights and exercises. 4. The most frequent site of rupture was 2–5 Cm. above the insertion of the tendon (80%). 5. By means of a cost immobilization, good result was obtained in fresh partial rupture of the tendon. 6. Good results were obtained by end-to-end suture in fresh cases and reconstructive surgery in old cases. 7. Most of the patients returned to their jobs about 6 months after the operation.
Accidental Falls
;
Achilles Tendon
;
Angiography
;
Arm
;
Clinical Study
;
Diagnosis
;
Early Diagnosis
;
Electromyography
;
Exercise
;
Female
;
Hospitals, General
;
Humans
;
Immobilization
;
Male
;
Methods
;
Orthopedics
;
Prognosis
;
Rupture
;
Sex Distribution
;
Sutures
;
Tendons
;
Walking
;
Weight-Bearing
10.A case ileal duplication with intussusception.
Gyoung Wha CHOI ; Gyoung Sun KANG ; Byung Uk PARK ; Wha Mo LEE ; Young Seak JEEN ; Tae Won LEE
Journal of the Korean Pediatric Society 1992;35(4):563-568
No abstract available.
Intussusception*