Available conventional pathologic diagnostic tools for lung cancer include sputum cytology, lung biopsy using bronchoscopy, and washing and brushing cytology. In addition, fine needle aspiration (FNA) cytology is now available and has become popular. In this study, an attempt was made to compare the relative sensitivity between conventional cytopathologic methods and FNA cytology, to study the clinical characteristics of lung cancer in which the diagnosis was established by FNA cytology, and to study the cellular findings and diagnostic criteria of lung cencers. Cases included in this study were selected from 105 patients who had been diagnosed an lung cancer at Yonsei University Medical Center during the 5-year period from January 1984 to December 1988. These 105 cases were reviewed with respect to medical records and pathologic slides and then the following conclusions were made. The mean age of cases was 58.5 years, and the sex ratio of males to females was 3.5:1. Tumors were mostly solitary in number and were mainly located at the periphery of the lung. The sensitivity of FNA cytology, sputum, and bronchial washing was as follows: FNA cytology was 0.93, sputum, 0.2, and bronchial washing, 0.14. The coincidence rate of cytopathologic diagnosis with histologic diagnosis was as follows: epidermoid carcinoma was 92%, adenocarcinoma 83%, undifferentiated large cell carcinoma 66%, and undifferentiated small cell carcinoma 100%. The false negativity of FNA cytology was 7%, which was mainly due to material insufficiency. For the differential diagnosis of histologic type, some brief criteria could be summarized. Differential diagnostic points of each histologic type were as follows: epidermoid carcinoma showed a large cellular group with keratinized cytoplasms and hyperchromatic and pyknotic nuclei, adenocarcinoma showed a glandular or ball-like arrangement by monotonous round cells, undifferentiated large cell carcinoma was mainly composed of irregular large cells and showed emperipolesis, and undifferentiated small cell carcinoma showed an Indian file appearance with molding by small, round hyperchromatic cells. In conclusion, FNA cytology is a more efficient, definite, and sensitive method for diagnosing lung cancer than other cytopathologic studies, so that careful selection of patients and experienced technique will improve the diagnostic accuracy of FNA cytology in diagnosing lung cancer.
Female ; Male ; Humans ; Diagnosis, Differential ; Adenocarcinoma ; Biopsy ; Lung Neoplasms

Available conventional pathologic diagnostic tools for lung cancer include sputum cytology, lung biopsy using bronchoscopy, and washing and brushing cytology. In addition, fine needle aspiration (FNA) cytology is now available and has become popular. In this study, an attempt was made to compare the relative sensitivity between conventional cytopathologic methods and FNA cytology, to study the clinical characteristics of lung cancer in which the diagnosis was established by FNA cytology, and to study the cellular findings and diagnostic criteria of lung cencers. Cases included in this study were selected from 105 patients who had been diagnosed an lung cancer at Yonsei University Medical Center during the 5-year period from January 1984 to December 1988. These 105 cases were reviewed with respect to medical records and pathologic slides and then the following conclusions were made. The mean age of cases was 58.5 years, and the sex ratio of males to females was 3.5:1. Tumors were mostly solitary in number and were mainly located at the periphery of the lung. The sensitivity of FNA cytology, sputum, and bronchial washing was as follows: FNA cytology was 0.93, sputum, 0.2, and bronchial washing, 0.14. The coincidence rate of cytopathologic diagnosis with histologic diagnosis was as follows: epidermoid carcinoma was 92%, adenocarcinoma 83%, undifferentiated large cell carcinoma 66%, and undifferentiated small cell carcinoma 100%. The false negativity of FNA cytology was 7%, which was mainly due to material insufficiency. For the differential diagnosis of histologic type, some brief criteria could be summarized. Differential diagnostic points of each histologic type were as follows: epidermoid carcinoma showed a large cellular group with keratinized cytoplasms and hyperchromatic and pyknotic nuclei, adenocarcinoma showed a glandular or ball-like arrangement by monotonous round cells, undifferentiated large cell carcinoma was mainly composed of irregular large cells and showed emperipolesis, and undifferentiated small cell carcinoma showed an Indian file appearance with molding by small, round hyperchromatic cells. In conclusion, FNA cytology is a more efficient, definite, and sensitive method for diagnosing lung cancer than other cytopathologic studies, so that careful selection of patients and experienced technique will improve the diagnostic accuracy of FNA cytology in diagnosing lung cancer.
Female ; Male ; Humans ; Diagnosis, Differential ; Adenocarcinoma ; Biopsy ; Lung Neoplasms

No Abstract Available.
Choroid*

We studied the change in intraocular pressure (IOP) in 15 consecutive cataract patients who underwent extracapsular cataract extraction and posterior chamber lens implantation between Feb. 1993 and Apr. 1993 to evaluate the effect of this surgery on postoperative IOP. To evaluate the clinical usefulness of non-contact tonometer, the intraocular pressures were measured with Kowa non-contact tonometer (TM-2000, Japan) as well as Goldmann applanation tonometer. There was a decrease in IOP of 3.4±2.9mmHg (p<0.001) 3 months after this surgery and the intraocular pressure differences between pseudophakic eyes and contralateral phakin eyes at 3 months postoperatively were 2.4±3.8mmHg (p<0.05). The correlation coefficient between non-contact tonometer and Goldmann tonometer was 0.8876 (p=0.001) in the postoperative 76 eyes. Therefore, out results suggest that extracapsular cataract extraction and posterior chamber lens implantation alone can be a useful surgical method in cataract patient with ocular hypertension, and non-contact tonometer was relatively accurate in measuring the postoperative intraocular pressure.
Cataract Extraction* ; Cataract* ; Humans ; Intraocular Pressure* ; Methods ; Ocular Hypertension

Malignant melanoma is considered as one of the tumor originated from precancerous melanosis and predilected in the iris and choroid. The Authors experienced a case of malignant melanoma affecting the upper palpebral conjunctiva in 39 year old female. The tumor mass was excised radically and followed by X-Ray therapy. Slight opacities of lens body is developed after X-ray irradiation.
Adult ; Choroid ; Conjunctiva* ; Female ; Humans ; Iris ; Melanoma* ; Melanosis ; X-Ray Therapy

Since that first description of the so-called granular cell myoblastoma by Abrikossoff in 1926, it has been reported as occuring in many sites. This tumor is an unusual but not rare tumor. From the number of reviewed case reports(550) upto now, it appears that the occurence of multiple granular cell tumors (36) is much more common (7–16%) than traditionally believed. The precise histogenesis of this tumor is open to question. Most of this tumor is benign, but malignant ones have been reported. A case of malignant granular cell myoblastoma which was histologically proven and metastasized to the coracoid process of left scapula, the lung, and the skull, is presented with a brief of the literature.
Axilla ; Granular Cell Tumor ; Lung ; Sarcoma, Alveolar Soft Part ; Scapula ; Skull

No abstract available.
Animals ; Evoked Potentials, Motor* ; Rats* ; Spinal Cord*

Reviewing 16 patients of fractures and dislocations of the cervical spine treated and managed at Department of Orthopedic Surgery, Kyungpook National University Hospital from January 1963 to August 1970 We came to the following conclusions: 1. The incidence of trauma was high in the young men, most frequent in the 3rd and 4th decades. 2 Most of the injuries were the results of automobile accidents or of falls on the head and neck. 3. Twelve of sixteen patients had dislocations or subluxations associated with the fractures and the remainder of 16 had dislocations or subluxations without demonstrable fractures. These occurred most often at the level of the 5th and 6th cervical vertebra. 4. Twelve of sixteen patients had a total of demonstrable fractures, and compression of a vertebral body was the most common type of fracture. 5. Trauma to the head was the commonest associated injury. 6. Mild or severe cord damage signs had developed in 12 of 16 patients; a case who was assocated with severe cerebral damage was dead, 7 were quadriplegic and 4 returned to former professional life. The remainder of 16 had a good recovery without disability.
Accidental Falls ; Automobiles ; Clinical Study ; Dislocations ; Gyeongsangbuk-do ; Head ; Humans ; Incidence ; Male ; Neck ; Orthopedics ; Spine

Os Subtibiale, inconstant bone over the tip of the medial malleolus, is the very unusual findings and extreme rarity of the condition. We experienced a case of Os subtibiale in a 24 year old man who complained pain and tenderness an the bilateral medial malleolar region. The patient was treated by excision with satisfactory result.
Humans

No abstract available.
Cardiopulmonary Bypass*