No abstract available.
Melanoma* ; Proliferating Cell Nuclear Antigen*

No abstract available.
Cleft Lip*

A case of Vogt-Koyanagi-Harada syndrome was presented with some clinical observation. Special feature was the presence of cyst-like elevated portions at the peripheral iris, in addition to secondary glaucoma, alopecia, poliosis and vitiligo. Of the iris, the surface of elevated portion was thin and depigmented. A light red fundus reflex was observed through the surface of iris cyst as in case of the albino and neovascularization was seen in the peripheral iris. Neither hyperglycemia in blood nor pleocytosis of spinal fluid was found in laboratory examination. In neurological examination including hearing disturbance, none of abnormality was found.
Alopecia ; Glaucoma ; Hearing ; Hyperglycemia ; Iris ; Leukocytosis ; Neurologic Examination ; Reflex ; Uveomeningoencephalitic Syndrome* ; Vitiligo

The choristoma is a tumor like mass of normal cells in an abnormal location. Intraoral osseous and cartilaginous choristoma is distinctly uncommon. The etiology of choristoma is unknown. It is suggested that the intraoral choristoma is a developmental lesion. Correct diagnosis can be obtained only after histopathologic examination. The treatment of choice is surgical excision. We present a case of osseous and cartilaginous choristoma, occurred on the tongue base and treated by peroral excision, with review of the literatures.
Choristoma* ; Diagnosis ; Tongue*

Benign tumors of the esophagus occur rarely as compared with the incidence of carcinomas. Among the benign tumors of the esophagus such as leiomyoma, lipoma, hemangioma, papilioma. polyp, cystetc. leiomyoma is the most common, although less than 10 percents of leiomyomas of the gastrointestinal tract are found in the esophagus. Most of leiomyomas of the esophagus present as solitary lesions but multiple tumors occur in about 4 percents of cases. Leiomyomas of the esophagus are diagnosed by thorough clinical evaluation, esophagogram and upper gastrofiberscopic examination but histological confirmation requires surgical or necropsy specimens. Occasionally gastrofiberscopic polypectomized specimens are used. We report one case of multiple leiomyomas of the esophagus located in between 25 cm and 40 cm distance from the incisor in a 38-year-old man who complained of vague substernal discomfort for about 10 years. Gastrofiberscopic polypectomized specimen was used for preoperative histological confirmation. The pathologic examination of the specimen showed leiomyoma of the esophagus.
Adult ; Esophagus* ; Gastrointestinal Tract ; Hemangioma ; Humans ; Incidence ; Incisor ; Leiomyoma* ; Lipoma ; Polyps

PURPOSE: This study was to examine the effect of electrical muscle stimulation therapy on chronic knee pain and depression for the aged. METHOD: Design was one-group pretest-posttest design. Samples were 32 elderly of 60 years old and above with chronic knee pain and depression. Measures were the S-F McGill Pain Questuionnaire for chronic knee pain and the Korean Elderly Depression Scale for depression. Electrical muscle stimulation therapy, experimental treatment, was applied for 12 weeks, 3 times/week, 15 min/time. Data were collected from January 2005 to May 2005. Data were analyzed using SPSS PC+ 12 version. RESULTS: After receiving electrical muscle stimulation therapy, chronic knee pain (t=-88.034, P=.000) and depression (t=-114.659, P=.000) were significantly decreased. CONCLUSION: Electrical muscle stimulation therapy can be a better effective primary nursing intervention on chronic knee pain and depression for community dwelling elders.
Aged ; Depression* ; Electric Stimulation Therapy ; Humans ; Knee* ; Middle Aged ; Primary Nursing ; Therapies, Investigational

Extensive clinical research has demonstrated that the 585-nm pulsed dye laser(PDL) is effective in eradicating port-wine stains(PWS) and telangiectasia with an extremely low incidence of scarring. The successful treatment of laser therapy is based on selective photothermolysis of blood vessels without damaging the normal overlying epidermis. Unfortunately, the native epidermal melanin acts as an optical shield that absorbs the laser light and reduces the heat generated in blood vessels. When melanin absorbs laser light, the resultant temperature increase can induce epidermal blistering. In these patients, the laser treatment dosages must be kept low, often subtherapeutic, to avoid damage to the epidermis and to prevent the possibility of scarring. Cryogen spray cooling of skin may be an effective method for minimizing epidermal thermal injury. The objective of this study is to determine histologically the effectiveness of the cryogen cooling by spraying the skin with a brief spurt of cryogen prior to the laser pulse, so as to reduce epidermal damage (hypo/hyperpigmentation) caused by this laser. We present a histologic study of the thermal response of the skin of the Sprague-Dawley rats to spray cooling in conjunction with 585-nm pulsed dye laser irradiation with 6J/cm. Both treatment sites with and without the use of the cryogen spray were compared. Under light microscope, the epidermal and dermal histologic changes were compared. A significant reduction in epidermal damage was found in study groups using the cryogen cooling without changing the efficacy of the laser treatment statistically. And a significant reduction in healing periods was observed in study groups using the cryogen cooling prior to the laser pulse. This study suggests that cryogen cooling can reduce epidermal damage during PWS treatment with the 585-nm PDL without reducing treatment efficacy. The absence of epidermal damage suggests that precooling with the cryogen may allow the use of higher laser input to expedite clearance without inducing epidermal change.
Blister ; Blood Vessels ; Cicatrix ; Epidermis ; Hot Temperature ; Humans ; Incidence ; Laser Therapy ; Lasers, Dye* ; Melanins ; Port-Wine Stain ; Rats, Sprague-Dawley ; Skin ; Telangiectasis ; Treatment Outcome

Chronic atrophic gastritis is a result of chronic inflammation characterized by the replacement of oxyntic and antral gastric glandular structures by connective tissue or by glandular structures inappropriate for location such as metaplastic atrophy. Chronic atrophic gastritis is considered as one of the major risk factors for noncardiac gastric cancer or mucosa associated lymphoid tissue lymphoma. Since chronic inflammation is generally considered to be triggered by Helicobacter pylori infection, many studies have evaluated whether H. pylori eradication therapy could make histologic improvement or reversal. However, it is controversial whether eradication of H. pylori improves atrophy or metaplasia. There has been a lot of conflict, but many previous studies including meta-analyses tend to demonstrate that it is possible that gastric atrophy could be improved after H. pylori eradication in the corpus but not in the antrum. Also, intestinal metaplasia seems to be irreversible even after H. pylori eradication.
Atrophy ; Carbamates ; Connective Tissue ; Gastritis, Atrophic ; Helicobacter pylori ; Inflammation ; Lymphoma, B-Cell, Marginal Zone ; Metaplasia ; Organometallic Compounds ; Risk Factors ; Stomach Neoplasms

Chronic atrophic gastritis is a result of chronic inflammation characterized by the replacement of oxyntic and antral gastric glandular structures by connective tissue or by glandular structures inappropriate for location such as metaplastic atrophy. Chronic atrophic gastritis is considered as one of the major risk factors for noncardiac gastric cancer or mucosa associated lymphoid tissue lymphoma. Since chronic inflammation is generally considered to be triggered by Helicobacter pylori infection, many studies have evaluated whether H. pylori eradication therapy could make histologic improvement or reversal. However, it is controversial whether eradication of H. pylori improves atrophy or metaplasia. There has been a lot of conflict, but many previous studies including meta-analyses tend to demonstrate that it is possible that gastric atrophy could be improved after H. pylori eradication in the corpus but not in the antrum. Also, intestinal metaplasia seems to be irreversible even after H. pylori eradication.
Atrophy ; Carbamates ; Connective Tissue ; Gastritis, Atrophic ; Helicobacter pylori ; Inflammation ; Lymphoma, B-Cell, Marginal Zone ; Metaplasia ; Organometallic Compounds ; Risk Factors ; Stomach Neoplasms

BACKGROUND: Recently, using propofol as intravenous anesthetic agent is increasing. And it is known that propofol has little effects on liver function even after long operation such as plastic surgery. But its effect on liver functon after hepatobilliary operation which may damage liver was not studied. Thus, authors carried out this study to evaluate the effect of propofol on liver function by comparing with enflurane in the patients who had laparoscopic cholecystectomy. METHODS: Patients's anesthesia records and hospital charts from January 1994 to June 1996 were anlaysed retrospectively. Three hundred and thirty three patients who had normal liver function preoperatively and had no complications during and after operation were selected. They were divided into two groups ; propofol group (n=191) and enflurane group (n=142). The preoperative values of aspartate aminotransferase (AST), alanine aminotransferase (ALT) and alkaline phosphatase (ALP) were compared with those of 1 and 3 days after operation. RESULTS: One day after operation, both propofol and enflurane group showed significant increase in AST and ALT (p<0.05) and decrease in ALP (p<0.05). But there was no difference between two groups. CONCLUSION: Concerned to liver function, propofol is as useful as enflurane to the patients who scheduled for laparoscopic cholecystectomy.
Alanine Transaminase ; Alkaline Phosphatase ; Anesthesia* ; Aspartate Aminotransferases ; Cholecystectomy, Laparoscopic* ; Enflurane* ; Humans ; Liver* ; Propofol* ; Retrospective Studies ; Surgery, Plastic